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羟基磷灰石/壳聚糖复合材料的制备及其在骨组织再生中的应用
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作者 彭晰明(综述) 周楚超 杨艳清(审校) 《中国美容医学》 2025年第3期189-193,共5页
羟基磷灰石人工骨是最有前途的生物医用材料之一,在骨科领域和药物释放方面有着广泛的应用和研究。然而单独的羟基磷灰石脆性高,降解速度慢,限制了其在临床上的使用。聚合物在结构上与细胞外基质类似,具有良好的生物相容性,可调控的生... 羟基磷灰石人工骨是最有前途的生物医用材料之一,在骨科领域和药物释放方面有着广泛的应用和研究。然而单独的羟基磷灰石脆性高,降解速度慢,限制了其在临床上的使用。聚合物在结构上与细胞外基质类似,具有良好的生物相容性,可调控的生物降解性。羟基磷灰石/壳聚糖复合材料具有良好的生物相容性和合适的力学性能,逐渐成为骨修复生物材料研究的热点。本文综述了羟基磷灰石/壳聚糖复合材料的制备及其在骨组织再生中的应用,并对羟基磷灰石/壳聚糖复合材料的研究发展方向进行展望。 展开更多
关键词 羟基磷灰石 壳聚糖 复合材料 生物材料 药物递送
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全扩张法外耳再造术在52例先天性小耳畸形患者中的应用体会 被引量:2
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作者 杨静 贾东辉 +3 位作者 乔嘉璐 彭晰明 陈相儒 杨艳清 《中国美容整形外科杂志》 CAS 2024年第4期210-212,232,共4页
目的总结采用大容量扩张器全扩张法外耳再造术对先天性小耳畸形患者的临床应用体会。方法回顾性分析自2013年9月至2022年8月,武汉市第三医院整形外科收治的52例先天性小耳畸形患者,手术分3期进行,一期行残耳耳后皮肤软组织扩张器置入术... 目的总结采用大容量扩张器全扩张法外耳再造术对先天性小耳畸形患者的临床应用体会。方法回顾性分析自2013年9月至2022年8月,武汉市第三医院整形外科收治的52例先天性小耳畸形患者,手术分3期进行,一期行残耳耳后皮肤软组织扩张器置入术,充分扩张耳后皮肤;二期手术取出扩张器,并取右侧肋软骨雕刻耳软骨支架,埋植于扩张后皮瓣下,得到立体耳形态;三期手术进行再造耳局部修整,使整体效果更加接近于正常耳。结果52例患者术后获随访6~36个月,46例再造耳耳部结构清晰立体,与健耳对称性好,软骨支架无移位变形。4例颅耳角变浅,三期行全厚皮片移植加深颅耳角;2例支架吸收,再造耳形态欠佳。结论对于先天性小耳畸形患者采用全扩张法外耳再造术,再造耳结构清晰立体,皮肤色泽质地均匀良好,并发症较少,解决了传统扩张法需要植皮的弊端,值得临床推广应用。 展开更多
关键词 小耳畸形 全耳郭再造术 皮肤软组织扩张器 颅耳角
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Paleomagnetic results from Late Carboniferous to Early Permian rocks in the northern Qiangtang terrane, Tibet, China, and their tectonic implications 被引量:6
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作者 YANG XingFeng CHENG Xin +6 位作者 ZHOU YaNan MA Lun ZHANG XiaoDong YAN ZhaoSheng peng ximing SU HaiLun WU HanNing 《Science China Earth Sciences》 SCIE EI CAS CSCD 2017年第1期124-134,共11页
Results of a systematic paleomagnetic study are reported based on Late Carboniferous to Early Permian sedimentary rocks on the north slope of the Tanggula Mountains, in the northern Qiangtang terrane (NQT), Tibet, C... Results of a systematic paleomagnetic study are reported based on Late Carboniferous to Early Permian sedimentary rocks on the north slope of the Tanggula Mountains, in the northern Qiangtang terrane (NQT), Tibet, China. Data revealed that magnetic minerals in limestone samples from the Zarigen Formation (CP^z)are primarily composed of magnetite, while those in sandstone samples from the Nuoribagaribao Formation (Pnr) are dominated by hematite alone, or hematite and magnetite in combination. Progressive thermal, or alternating field, demagnetization allowed us to isolate a stable high temperature component (HTC) in 127 specimens from 16 sites which successfully passed the conglomerate test, consistent with primary remnance. The tilt-corrected mean direction for Late Carboniferous to Early Permian rocks in the northern Qiangtang terrane is D°=30.2°, Is=-40.9°, ks=269.0, a95=2.3°, N=16, which yields a corresponding paleomagnetic pole at 25.7°N, 241.5°E (alp/rim=2.8°/1.7°), and a paleolatitude of 23.4°S. Our results, together with previously reported paleomagnetic data, indicate that: (1) the NQT in Tibet, China, was located at a low latitude in the southern hemisphere, and may have belonged to the northern margin of Gondwana during the Late Carboniferous to Early Permian; (2) the Paleo-Tethys Ocean was large during the Late Carboniferous to Early Permian, and (3) the NQT subsequently moved rapidly northwards, perhaps related to the fact that the Paleo-Tethys Ocean was rapidly contracting from the Late Permian to Late Triassic while the Bangong Lake-Nujiang Ocean, the northern branch of the Neo-Tethys Ocean, expanded rapidly during this time. 展开更多
关键词 Northem Qiangtang terrane Late Carboniferous Early Permian Rock magnetism Conglomerate test Paleomagnetic pole
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