Since the Cenozoic,the Tibetan Plateau has experienced large-scale uplift and outgrowth due to the India-Asia collision.However,the mechanism and timing of these tectonic processes still remain debated.Here,using apat...Since the Cenozoic,the Tibetan Plateau has experienced large-scale uplift and outgrowth due to the India-Asia collision.However,the mechanism and timing of these tectonic processes still remain debated.Here,using apatite fission track dating and inverse thermal modeling,we explore the mechanism of different phases of rapid cooling for different batholiths and intrusions in the southeastern Tibetan Plateau.In contrast to previous views,we find that the coeval granitic batholith exposed in the same tectonic zone experienced differential fast uplift in different sites,indicating that the present Tibetan Plateau was the result of differential uplift rather than the entire lithosphere uplift related to lithospheric collapse during Cenozoic times.In addition,we also suggest that the 5-2 Ma mantle-related magmatism should be regarded as the critical trigger for the widely coeval cooling event in the southeastern Tibetan Plateau,because it led to the increase in atmospheric CO_(2)level and a hotter upper crust than before,which are efficient for suddenly fast rock weathering and erosion.Finally,we propose that the current landform of the southeastern Tibetan Plateau was the combined influences of tectonic and climate.展开更多
目的探究手术室不同输血方式与骨伤科患者术后感染的相关性。方法按照输血方式不同将98例骨伤科患者分为自体输血组及异体输血组,收集患者手术时间、失血量、输血量等围术期指标及术后感染发生情况,测定患者术前及术后3、7 d时白细胞(W...目的探究手术室不同输血方式与骨伤科患者术后感染的相关性。方法按照输血方式不同将98例骨伤科患者分为自体输血组及异体输血组,收集患者手术时间、失血量、输血量等围术期指标及术后感染发生情况,测定患者术前及术后3、7 d时白细胞(WBC)计数、红细胞(RBC)计数、血红蛋白(Hb)、血小板(PLT)计数等血常规指标及白细胞介素-8(IL-8)及肿瘤坏死因子(TNF-α)等炎症因子水平。结果两组患者手术时间、术中出血量、输血量等临床资料比较,差异无统计学意义(P>0.05);异体输血组患者术后感染总发生率显著高于自体输血组(P<0.05);术后3 d WBC计数较术前升高,RBC计数、Hb水平及PLT计数较术前显著下降(P<0.05);自体输血组患者Hb水平及PLT计数升高或下降的幅度小于异体输血组患者,差异具统计学意义(P<0.05);自体输血组术后各时间段免疫因子水平较术前显著升高(P<0.05),而异体输血组各时间段较术前无显著性差异(P>0.05)。结论骨伤科手术术中应用自体输血方式患者造血功能恢复较快,免疫抑制程度较异体输血轻微,可减少异体输血引起的术后感染及并发症。展开更多
基金supported by National Natural Science Foundation of China(Grant Nos.42025301,41730213 and 41890831)the Second Tibetan Plateau Scientific Expedition and Research Program(Grant No.2019QZKK0702)+2 种基金Hong Kong RGC GRF(Grant No.17307918)HKU Internal Grants for Member of Chinese Academy of Sciences(Grant No.102009906)for Distinguished Research Achievement Award(Grant No.102010100)。
文摘Since the Cenozoic,the Tibetan Plateau has experienced large-scale uplift and outgrowth due to the India-Asia collision.However,the mechanism and timing of these tectonic processes still remain debated.Here,using apatite fission track dating and inverse thermal modeling,we explore the mechanism of different phases of rapid cooling for different batholiths and intrusions in the southeastern Tibetan Plateau.In contrast to previous views,we find that the coeval granitic batholith exposed in the same tectonic zone experienced differential fast uplift in different sites,indicating that the present Tibetan Plateau was the result of differential uplift rather than the entire lithosphere uplift related to lithospheric collapse during Cenozoic times.In addition,we also suggest that the 5-2 Ma mantle-related magmatism should be regarded as the critical trigger for the widely coeval cooling event in the southeastern Tibetan Plateau,because it led to the increase in atmospheric CO_(2)level and a hotter upper crust than before,which are efficient for suddenly fast rock weathering and erosion.Finally,we propose that the current landform of the southeastern Tibetan Plateau was the combined influences of tectonic and climate.
文摘目的探究手术室不同输血方式与骨伤科患者术后感染的相关性。方法按照输血方式不同将98例骨伤科患者分为自体输血组及异体输血组,收集患者手术时间、失血量、输血量等围术期指标及术后感染发生情况,测定患者术前及术后3、7 d时白细胞(WBC)计数、红细胞(RBC)计数、血红蛋白(Hb)、血小板(PLT)计数等血常规指标及白细胞介素-8(IL-8)及肿瘤坏死因子(TNF-α)等炎症因子水平。结果两组患者手术时间、术中出血量、输血量等临床资料比较,差异无统计学意义(P>0.05);异体输血组患者术后感染总发生率显著高于自体输血组(P<0.05);术后3 d WBC计数较术前升高,RBC计数、Hb水平及PLT计数较术前显著下降(P<0.05);自体输血组患者Hb水平及PLT计数升高或下降的幅度小于异体输血组患者,差异具统计学意义(P<0.05);自体输血组术后各时间段免疫因子水平较术前显著升高(P<0.05),而异体输血组各时间段较术前无显著性差异(P>0.05)。结论骨伤科手术术中应用自体输血方式患者造血功能恢复较快,免疫抑制程度较异体输血轻微,可减少异体输血引起的术后感染及并发症。
