The perovskite-like NaMgF3 polycrystalline powder samples, pure and rare earth doped, were synthesized by conventional solid state reaction method. The perovskite material was doped with 0.2 mol.% of EuF3 and CeF3 imp...The perovskite-like NaMgF3 polycrystalline powder samples, pure and rare earth doped, were synthesized by conventional solid state reaction method. The perovskite material was doped with 0.2 mol.% of EuF3 and CeF3 impurity. Phase purity of synthe-sized compounds was analyzed by powder X-ray diffraction technique. The thermoluminescence response of polycrystalline samples showed a linear response up to 12 Gy and then became sub linear at higher doses. The order of kinetics （b）, activation energy （E） and other trapping parameters were calculated using peak shape method and variable heating rate method. From glow curve analysis the symmetric factor was calculated. The glow curve showed two peaks at 404 and 488 K, and both of them confirmed the thermolumi-nescence in the phosphor, which obeyed second-order kinetics. The experimental resulted showed that this phosphor could have po-tential applications in radiation dosimetry.展开更多
Crude phlorotannins from Eisenia bicyclis(CPEb),a common perennial brown seaweed were screened for pharmacological activities such as anti-inflammatory,antioxidant,and antidiabetic effects.Crude Phlorotannins(CPEb)stu...Crude phlorotannins from Eisenia bicyclis(CPEb),a common perennial brown seaweed were screened for pharmacological activities such as anti-inflammatory,antioxidant,and antidiabetic effects.Crude Phlorotannins(CPEb)studied by FT-IR,LC-MS,UHPLC,and UV chromatography showed the occurrence of dieckol,8,8’-bieckol,fucofuroeckol,and the carotenoid,zeaxanthin(0.5 mg/kg).LPS,an inflammatory mediator,enhanced the production of cytokines such IL-1(interleukin-1),IL-6(interleukin-6),IL-8(interleukin-8),IL-10(interleukin-10),TNF-α(tumour necrosis factor-α),chemokine CXCL10,and NF-κB(nuclear factor kappa-light-chain-enhancer of activated B cells)in differentiated THP1 macrophage cells.On differentiated human monocytic cell line LPS-induced THP1 cells,CPEb was found to have anti-inflammatory effects by reducing the expression of IL-1,IL-6,IL-8(1.2 fold),CXCL10,NF-κB,and TNF-α.CPEb promoted 2-NBDG absorption in differentiated C2C12 myotubes under both basal(16.08%)and insulin-stimulated(51.09%)conditions.CPEb increased IRS/AKT-dependent glucose absorption and also activates the AMPK pathway.Anti-α-glucosidase,anti-inflammatory and antioxidant activity of CPEb indicate their role in treating hyperglycemia by scavenging ROS and inflammatory responses.展开更多
基金Project supported by Indira Gandhi Centre for Atomic Research(IGCAR),Department of Atomic Energy,Government of India(W.O.N.O.IGC/SG/RSD/WO/2009)
文摘The perovskite-like NaMgF3 polycrystalline powder samples, pure and rare earth doped, were synthesized by conventional solid state reaction method. The perovskite material was doped with 0.2 mol.% of EuF3 and CeF3 impurity. Phase purity of synthe-sized compounds was analyzed by powder X-ray diffraction technique. The thermoluminescence response of polycrystalline samples showed a linear response up to 12 Gy and then became sub linear at higher doses. The order of kinetics （b）, activation energy （E） and other trapping parameters were calculated using peak shape method and variable heating rate method. From glow curve analysis the symmetric factor was calculated. The glow curve showed two peaks at 404 and 488 K, and both of them confirmed the thermolumi-nescence in the phosphor, which obeyed second-order kinetics. The experimental resulted showed that this phosphor could have po-tential applications in radiation dosimetry.
文摘Crude phlorotannins from Eisenia bicyclis(CPEb),a common perennial brown seaweed were screened for pharmacological activities such as anti-inflammatory,antioxidant,and antidiabetic effects.Crude Phlorotannins(CPEb)studied by FT-IR,LC-MS,UHPLC,and UV chromatography showed the occurrence of dieckol,8,8’-bieckol,fucofuroeckol,and the carotenoid,zeaxanthin(0.5 mg/kg).LPS,an inflammatory mediator,enhanced the production of cytokines such IL-1(interleukin-1),IL-6(interleukin-6),IL-8(interleukin-8),IL-10(interleukin-10),TNF-α(tumour necrosis factor-α),chemokine CXCL10,and NF-κB(nuclear factor kappa-light-chain-enhancer of activated B cells)in differentiated THP1 macrophage cells.On differentiated human monocytic cell line LPS-induced THP1 cells,CPEb was found to have anti-inflammatory effects by reducing the expression of IL-1,IL-6,IL-8(1.2 fold),CXCL10,NF-κB,and TNF-α.CPEb promoted 2-NBDG absorption in differentiated C2C12 myotubes under both basal(16.08%)and insulin-stimulated(51.09%)conditions.CPEb increased IRS/AKT-dependent glucose absorption and also activates the AMPK pathway.Anti-α-glucosidase,anti-inflammatory and antioxidant activity of CPEb indicate their role in treating hyperglycemia by scavenging ROS and inflammatory responses.
