This paper reports the most prominent contributions in the field of biodegradable polymeric nanoparticles from poly (lactic-co-glycolic acid) (PLGA) used as a protein/drug delivery. We use a combination of Human Serum...This paper reports the most prominent contributions in the field of biodegradable polymeric nanoparticles from poly (lactic-co-glycolic acid) (PLGA) used as a protein/drug delivery. We use a combination of Human Serum Albumin (HSA)-superparamagnetic iron oxide nanoparticles (SPIONs) loaded PLGA nanoparticles. To obtain protein stabilization, the optimization of each step of synthesis nanoparticle is required. One of the most common problems in encapsulating protein to PLGA nanoparticles is the presence of several challenges as a problem of instability. We explained how the effect of the various sonication processing on the synthesis HSA-SPIONs loaded PLGA nanoparticles would be one of the crucial parameters for stability.展开更多
文摘This paper reports the most prominent contributions in the field of biodegradable polymeric nanoparticles from poly (lactic-co-glycolic acid) (PLGA) used as a protein/drug delivery. We use a combination of Human Serum Albumin (HSA)-superparamagnetic iron oxide nanoparticles (SPIONs) loaded PLGA nanoparticles. To obtain protein stabilization, the optimization of each step of synthesis nanoparticle is required. One of the most common problems in encapsulating protein to PLGA nanoparticles is the presence of several challenges as a problem of instability. We explained how the effect of the various sonication processing on the synthesis HSA-SPIONs loaded PLGA nanoparticles would be one of the crucial parameters for stability.
