<strong>Background:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> Hypertriglyceridemia in children means increased plasma fasti...<strong>Background:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> Hypertriglyceridemia in children means increased plasma fasting Triglyceride levels above the 95</span><sup><span style="font-family:Verdana;">th</span></sup><span style="font-family:Verdana;"> percentile for age and sex. For children aged 0 to 9 years, a triglyceride level greater than or equal to 100 mg/dl is considered above the 95</span><sup><span style="font-family:Verdana;">th</span></sup><span style="font-family:Verdana;"> percentile. Hypertriglyceridemia can be mild to borderline high, moderate to high, very high, severe and very severe (>2000 mg/dl).</span></span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">We present the case of a 1</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">month and </span><span style="font-family:Verdana;">3 </span><span style="font-family:Verdana;">week</span><span style="font-family:Verdana;">s </span><span style="font-family:Verdana;">old baby who presented with difficulty in breathing. </span><span style="font-family:Verdana;">It </span><span style="font-family:;" "=""><span style="font-family:Verdana;">was accidentally found to have strawberry yoghurt like blood during phlebotomy, of which upon investigation had very high triglyceride levels of >2000 mg/dl. </span><b><span style="font-family:Verdana;">Case Presentation:</span></b><span style="font-family:Verdana;"> 1 month and 3</span></span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">weeks old female baby, admitted as referral from nearby health centre presenting with difficulty in breath, her blood sample was incidentally found to appear as strawberry yoghurt like. Clinically the infant had features suggestive of respiratory distress, with no other systemic abnormalities noted. Chest X</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">ray that was done had features of pneumonia. The working diagnosis on admission was Pneumonia, Electrolyte imbalance. The strawberry yoghurt like blood raised suspicions of hypertriglyceridemia. Our triglyceride levels in the infant were very high at 136 mmol/l (12,046 mg/dl).</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">The patient was treated with IV antibiotics for pneumonia, electrolytes were corrected and Rosuvastatin was started. This patient improved remarkably and was discharged with Rosuvastatin. Lipid profile was followed up for 4 consecutive months in our outpatient clinic with a drastic drop in triglyceride and cho</span><span><span style="font-family:Verdana;">lesterol. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">We report a case of infantile hypertriglyceridemia </span></span><span style="font-family:Verdana;">found accidentally during phlebotomy. Despite limited resource to evaluate further on primary cause of this condition as well as family’s poor economic status to seek further medical evaluation outside the country, this case report raises awareness on how to deal with this condition in a low resource setting. It also highlights the role of statins in the treatment of hypertriglyceridemia.</span></span>展开更多
Background: Orphans are potentially at greater risk of malnutrition because they are more likely to be extremely poor and receive less medical and social care. Children living in orphanages tend to be neglected and ma...Background: Orphans are potentially at greater risk of malnutrition because they are more likely to be extremely poor and receive less medical and social care. Children living in orphanages tend to be neglected and may be malnourished and they’re at risk of losing their full potential, with consequences to the child, nation and worldwide. Despite the nutritional concerns raised globally and in neighboring countries among these children, there exists an inadequate body of information about orphans’ nutritional status and feeding practices in Tanzania. This study aimed to assess the nutritional status, feeding practices and factors contributing to malnutrition among children aged 6 - 59 months in Arusha region orphanages, Tanzania. Study Objective: To assess the nutritional status, feeding practices and factors contributing to undernutrition among children aged 6 - 59 months in Arusha region orphanages, Tanzania. Methodology: This was an institution-based cross-sectional study conducted in selected orphanage Centre in the Arusha region. A representative sample size of 216 children aged 6 - 59 months in Arusha orphanages was selected to participate in the study. Multistaging sampling was used to select the study participants. Interviewer-administered questionnaires and anthropometric measurements were used during data collection. The data collected were entered, processed, and analyzed;continuous variables were summarized by use of mean and Standard deviation, while categorical variables were summarized by use of frequency, percentages and figures. Multivariable logistic regression was used to estimate the Odds Ratio with 95% CI and measure the strength of association between the outcomes with respect to selected independent variables. Variables with a p-value of less than 0.05 were considered statistically significant. Results: A total of 216 children from the orphanage Centre were involved in this study. Prevalence of Stunting, underweight and wasting among orphan children were 23.60%, 15.30% and 9.30%. The proportions of MDD and MMF were 89% and 99%. Children being on medication for any kind of illness during the survey (AOR: 7.9;95% CI: 1.95, 31.78), unmarried caregivers (AOR: 1.9;95% CI: 1.32, 10.86), fever 2 weeks before the survey (AOR: 2.9;95% CI: 1.09, 9.24) and orphanage Centre with more than 30 children (AOR: 1.8;95% CI: 1.08, 6.86) were found to be associated with undernutrition. Conclusion: In Arusha orphanages, the prevalence of stunting, underweight, and wasting among children exceeded WHO standards. Despite adequate feeding practices, the child’s illness, the number of children in the orphanage, and the marital status of caregivers were factors influencing the nutritional status of the orphans.展开更多
文摘<strong>Background:</strong><span style="font-family:;" "=""><span style="font-family:Verdana;"> Hypertriglyceridemia in children means increased plasma fasting Triglyceride levels above the 95</span><sup><span style="font-family:Verdana;">th</span></sup><span style="font-family:Verdana;"> percentile for age and sex. For children aged 0 to 9 years, a triglyceride level greater than or equal to 100 mg/dl is considered above the 95</span><sup><span style="font-family:Verdana;">th</span></sup><span style="font-family:Verdana;"> percentile. Hypertriglyceridemia can be mild to borderline high, moderate to high, very high, severe and very severe (>2000 mg/dl).</span></span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">We present the case of a 1</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">month and </span><span style="font-family:Verdana;">3 </span><span style="font-family:Verdana;">week</span><span style="font-family:Verdana;">s </span><span style="font-family:Verdana;">old baby who presented with difficulty in breathing. </span><span style="font-family:Verdana;">It </span><span style="font-family:;" "=""><span style="font-family:Verdana;">was accidentally found to have strawberry yoghurt like blood during phlebotomy, of which upon investigation had very high triglyceride levels of >2000 mg/dl. </span><b><span style="font-family:Verdana;">Case Presentation:</span></b><span style="font-family:Verdana;"> 1 month and 3</span></span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">weeks old female baby, admitted as referral from nearby health centre presenting with difficulty in breath, her blood sample was incidentally found to appear as strawberry yoghurt like. Clinically the infant had features suggestive of respiratory distress, with no other systemic abnormalities noted. Chest X</span><span style="font-family:Verdana;">-</span><span style="font-family:Verdana;">ray that was done had features of pneumonia. The working diagnosis on admission was Pneumonia, Electrolyte imbalance. The strawberry yoghurt like blood raised suspicions of hypertriglyceridemia. Our triglyceride levels in the infant were very high at 136 mmol/l (12,046 mg/dl).</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">The patient was treated with IV antibiotics for pneumonia, electrolytes were corrected and Rosuvastatin was started. This patient improved remarkably and was discharged with Rosuvastatin. Lipid profile was followed up for 4 consecutive months in our outpatient clinic with a drastic drop in triglyceride and cho</span><span><span style="font-family:Verdana;">lesterol. </span><b><span style="font-family:Verdana;">Conclusion: </span></b><span style="font-family:Verdana;">We report a case of infantile hypertriglyceridemia </span></span><span style="font-family:Verdana;">found accidentally during phlebotomy. Despite limited resource to evaluate further on primary cause of this condition as well as family’s poor economic status to seek further medical evaluation outside the country, this case report raises awareness on how to deal with this condition in a low resource setting. It also highlights the role of statins in the treatment of hypertriglyceridemia.</span></span>
文摘Background: Orphans are potentially at greater risk of malnutrition because they are more likely to be extremely poor and receive less medical and social care. Children living in orphanages tend to be neglected and may be malnourished and they’re at risk of losing their full potential, with consequences to the child, nation and worldwide. Despite the nutritional concerns raised globally and in neighboring countries among these children, there exists an inadequate body of information about orphans’ nutritional status and feeding practices in Tanzania. This study aimed to assess the nutritional status, feeding practices and factors contributing to malnutrition among children aged 6 - 59 months in Arusha region orphanages, Tanzania. Study Objective: To assess the nutritional status, feeding practices and factors contributing to undernutrition among children aged 6 - 59 months in Arusha region orphanages, Tanzania. Methodology: This was an institution-based cross-sectional study conducted in selected orphanage Centre in the Arusha region. A representative sample size of 216 children aged 6 - 59 months in Arusha orphanages was selected to participate in the study. Multistaging sampling was used to select the study participants. Interviewer-administered questionnaires and anthropometric measurements were used during data collection. The data collected were entered, processed, and analyzed;continuous variables were summarized by use of mean and Standard deviation, while categorical variables were summarized by use of frequency, percentages and figures. Multivariable logistic regression was used to estimate the Odds Ratio with 95% CI and measure the strength of association between the outcomes with respect to selected independent variables. Variables with a p-value of less than 0.05 were considered statistically significant. Results: A total of 216 children from the orphanage Centre were involved in this study. Prevalence of Stunting, underweight and wasting among orphan children were 23.60%, 15.30% and 9.30%. The proportions of MDD and MMF were 89% and 99%. Children being on medication for any kind of illness during the survey (AOR: 7.9;95% CI: 1.95, 31.78), unmarried caregivers (AOR: 1.9;95% CI: 1.32, 10.86), fever 2 weeks before the survey (AOR: 2.9;95% CI: 1.09, 9.24) and orphanage Centre with more than 30 children (AOR: 1.8;95% CI: 1.08, 6.86) were found to be associated with undernutrition. Conclusion: In Arusha orphanages, the prevalence of stunting, underweight, and wasting among children exceeded WHO standards. Despite adequate feeding practices, the child’s illness, the number of children in the orphanage, and the marital status of caregivers were factors influencing the nutritional status of the orphans.
