Held on 8 May 2025,the 10th UN Multi-stakeholder Forum on Science,Technology and Innovation for the Sustainable Development Goals side event,titled"One Health for All:Synergistic Solutions Advancing SDG3 through ...Held on 8 May 2025,the 10th UN Multi-stakeholder Forum on Science,Technology and Innovation for the Sustainable Development Goals side event,titled"One Health for All:Synergistic Solutions Advancing SDG3 through Sustainable Science&Inclusive Innovation",convened global experts to explore integrated strategies for advancing human,animal,and environmental health within the 2030 Agenda.The event highlighted innovations like artificial intelligence(AI)-driven surveillance and low-carbon diagnostics,emphasizing equity and Sustainable Development Goals(SDGs)acceleration.One milestone was the launch of an expert consensus promoting the global One Health index(GOHI),a roadmap to align research and experimental development(R&D)with SDG3 targets.Discussions centered on three key issues covering:the One Health approach for SDGs,the role of GOHI as a scientific tool addressing data fragmentation and capacity disparities,and GOHI's potential to enhance cross-sectoral governance,exemplified by case studies from Japan,Cambodia,and Singapore.A consensus emerged to promote GOHI at the sub-national level,recognizing its value as a comprehensive,structured framework offering practical tools,data transformation capabilities,economic analysis,and global knowledge sharing,despite implementation challenges.Six actionable recommendations were proposed,focusing on strengthening institutional coordination,bridging data gaps,integrating GOHI into governance,piloting localized interventions,mobilizing funding,and building capacity through global partnerships.The event marked a significant step forward,positioning the One Health framework,facilitated by tools like GOHI,as essential for achieving the SDGs and ensuring a healthier,more sustainable future for all.展开更多
Background:Emerging infectious diseases(EIDs)pose significant public health challenges due to increasing interactions between humans,animals,and the environment.The One Health framework,an interdisciplinary and collab...Background:Emerging infectious diseases(EIDs)pose significant public health challenges due to increasing interactions between humans,animals,and the environment.The One Health framework,an interdisciplinary and collaborative approach,plays a critical role in the risk assessment of EIDs.The study aims to systematically review the risk assessment of EIDs in China under the One Health framework,covering policy support,monitoring and assessment systems,and implementation methods.Methods:Relevant literature and official documents between 1997 and 2024 were retrieved from Web of Science,PubMed,Scopus,China National Knowledge Infrastructure,Wan Fang,China Science and Technology Journal Database,and government websites.Data were synthesized to analyze progress,challenges,and gaps.Results:There were 43 academic studies and 31 official documents included in this review.The study found that risk assessment systems existed across human,animal,and environmental health sectors in China,and the government was advancing intelligent monitoring and fostering inter-departmental cooperation.However,several challenges remain in risk assessment of EIDs,including inadequate monitoring systems for unknown EIDs,limited capacity building for risk assessment in ecosystems and environmental systems,insufficiently detailed risk assessment guidance at the county level,and barriers to cross-sectoral information sharing at the international and county levels.Conclusion:The findings highlighted the need to enhance risk assessment of EIDs at the local level,expand the scope of disease surveillance including aquatic and wild animals,and strengthen inter-departmental data sharing to improve early warning capabilities under the One Health framework.展开更多
Background:Understanding the global burden of enteric infections is crucial for prioritizing control strategies for foodborne and waterborne diseases.This study aimed to assess the global burden of enteric infections ...Background:Understanding the global burden of enteric infections is crucial for prioritizing control strategies for foodborne and waterborne diseases.This study aimed to assess the global burden of enteric infections in 2021 and identify risk factors from One Health aspects.Methods:Leveraging the Global Burden of Disease(GBD)2021 database,the incidence,disability-adjusted life years(DALYs),and deaths of enteric infections and the subtypes were estimated,including diarrheal diseases,typhoid and paratyphoid fever,invasive non-typhoidal Salmonella(iNTS)infections,and other intestinal infectious diseases.The estimates were quantified by absolute number,age-standardized incidence rate(ASIR),agestandardized mortality rate(ASMR)and age-standardized DALY rate with 95%uncertainty intervals(UIs).Thirteen pathogens and three risk factors associated with diarrheal diseases were analyzed.Results:In 2021,the global age-standardized DALY rate of enteric infections was 1020.15 per 100,000 popultion(95%UI:822.70-1259.39 per 100,000 population)with an estimated annual percentage change(EAPC)of-4.11%(95%confidence interval:-4.31%to-3.90%)in 1990-2021.A larger burden was observed in regions with lower socio-demographic index(SDI)levels.Diarrheal disease was the most serious subtype with Western Sub-Saharan Africa exhibiting the highest age-standardized DALY rate(2769.81 per 100,000 population,95%UI:1976.80-3674.41 per 100,000 population).Children under 5 and adults over 65 years suffered more from diarrheal diseases with the former experiencing the highest global age-standardized DALY rate(9382.46 per 100,000 population,95%UI:6771.76-13,075.12 per 100,000 population).Rotavirus remained the leading cause of diarrheal diseases despite a cross-year decline in the observed age-standardized DALY rate.Unsafe water,sanitation,and handwashing contributed most to the disease burden.Conclusion:The reduced burden of enteric infections suggested the effectiveness of previous control strategies;however,more efforts should be made in vulnerable regions and populations through a One Health approach.展开更多
Background:In the 21st century,as globalization accelerates and global public health crises occur,the One Health approach,guided by the holistic thinking of human-animal-environment and emphasizing interdisciplinary c...Background:In the 21st century,as globalization accelerates and global public health crises occur,the One Health approach,guided by the holistic thinking of human-animal-environment and emphasizing interdisciplinary collaboration to address global health issues,has been strongly advocated by the international community.An immediate requirement exists for the creation of an assessment tool to foster One Health initiatives on both global and national scales.Methods:Built upon extensive expert consultations and dialogues,this follow-up study enhances the 2022 global One Health index(GOHI)indicator system.The GOHI framework is enriched by covering three indices,e.g.external drivers index(EDI),intrinsic drivers index(IDI),and core drivers index(CDI).The comprehensive indicator system incorporates 13 key indicators,50 indicators,and 170 sub I-indicators,utilizing a fuzzy analytic hierarchy process to ascertain the weight for each indicator.Weighted and summed,the EDI,IDI,and CDI scores contribute to the computation of the overall GOHI 2022 score.By comparing the ranking and the overall scores among the seven regions and across 160 countries/territories,we have not only derived an overall profile of the GOHI 2022 scores,but also assessed the GOHI framework.We also compared rankings of indicators and sub Iindicators to provide greater clarity on the strengths and weaknesses of each region within the One Health domains.Results:The GOHI 2022 performance reveals significant disparities between countries/territories ranged from 39.03 to 70.61.The global average score of the GOHI 2022 is 54.82.The average score for EDI,IDI,and CDI are 46.57,58.01,and 57.25,respectively.In terms of global rankings,countries from North America,Europe and Central Asia,East Asia and Pacific present higher scores.In terms of One Health domains of CDI,the lowest scores are observed in antimicrobial resistance(median:43.09),followed by food security(median:53.78),governance(median:54.77),climate change(median:64.12)and zoonotic diseases(median:69.23).Globally,the scores of GOHI vary spatially,with the highest score in North America while lowest in sub-Saharan Africa.In addition,evidence shows associations between the socio-demographic profile of countries/territories and their GOHI performance in certain One Health scenarios.Conclusion:The objective of GOHI is to guide impactful strategies for enhancing capacity building in One Health.With advanced technology and an annually updated database,intensifying efforts to refine GOHI's data-mining methodologies become imperative.The goal is to offer profound insights into disparities and progressions in practical One Health implementation,particularly in anticipation of future pandemics.展开更多
Background:One Health is an integrated concept of health that aims to optimize the health of humans,animals,plants,and the environment.Identifying research gaps and specific expertise areas is important for understand...Background:One Health is an integrated concept of health that aims to optimize the health of humans,animals,plants,and the environment.Identifying research gaps and specific expertise areas is important for understanding the role of One Health in practice.This information on One Health could be used to promote collaboration and research,inspire innovative ideas,and accelerate the translation of evidence-based practices into policies.Methods:We searched the Scopus database for publications related to One Health between 2012 and 2021 to extract bibliometric information and investigate the possibility of establishing a dedicated expertise database.We matched scholarly information using SciVal to exclude duplicate information and identify scholars’affiliations,countries,and academic profiles.Individual academic contributions to One Health were evaluated according to their citations,publication impact,publication type,and author contributions.Results:A total of 8,313 publications on One Health over a ten-year period were identified,with the number of publications increasing over time.The largest number of publications came from the United States and the United Kingdom.These countries also had the highest number of experts and a high level of international collaboration.We identified 500 scholars from 53 countries and 313 affiliations with a median Hirsch Index of 20 who could be included in a One Health expert database.These scientists had a median of six publications on One Health,with topics mostly focusing on dengue and antimicrobial resistance.Conclusion:A One Health information database could be used as a third-party reference for scholars,a source to track the ongoing academic progress,and support for active scholars in this field of research.展开更多
Following publication of the original article[1],it was found the number of countries with identified One Health publications was incorrectly shown in Table 2,Supplementary data-Multimedia component 3(Table-S2),corres...Following publication of the original article[1],it was found the number of countries with identified One Health publications was incorrectly shown in Table 2,Supplementary data-Multimedia component 3(Table-S2),corresponding text and Fig.3,which should be corrected to 178.The number of countries with 500 One Health experts identified should be corrected to 53 in the abstract.展开更多
Emerging infectious diseases(EIDs)pose a significant threat to public health.Effective surveillance and early warning systems that monitor EIDs in a timely manner are crucial for their control.Given that more than hal...Emerging infectious diseases(EIDs)pose a significant threat to public health.Effective surveillance and early warning systems that monitor EIDs in a timely manner are crucial for their control.Given that more than half of EIDs are zoonotic,traditional integrated surveillance systems remain inadequate.Despite recent advances in integrated systems in China,there are few systemic reviews on the integrated surveillance and early warning system of EIDs at community level,particularly under the One Health framework.Here,this systematic review summarizes the current status of surveillance advances in China,including the multi-trigger integrated monitor system.It also highlights the mechanisms for embedding the One Health approach into local policy and practice,while identifying challenges and opportunities for improvement.Additionally,guidelines and recommendations are proposed to optimize the integration of multi-sectoral,multi-level and interdisciplinary cooperation at the human-animal-environment interface.展开更多
Background Food systems instantiate the complex interdependencies across humans,physical environments,and other organisms.Applying One Health approaches for agri-food system transformation,which adopts integrated and ...Background Food systems instantiate the complex interdependencies across humans,physical environments,and other organisms.Applying One Health approaches for agri-food system transformation,which adopts integrated and unifying approaches to optimize the overall health of humans,animals,plants,and environments,is crucial to enhance the sustainability of food systems.This study develops a potential assessment tool,named the global One Health index-Food Security(GOHI-FS),aiming to evaluate food security performance across countries/territories from One Health perspective and identify relevant gaps that need to be improved for sustainable food systems.Methods We comprehensively reviewed existing frameworks and elements of food security.The indicator framework of GOHI-FS was conceptualized following the structure-process-outcome model and confirmed by expert advisory.Publicly available data in 2020 was collected for each indicator.The weighting strategy was determined by the Fuzzy Analytical Hierarchy Process.The data for each indicator was normalized and aggregated by weighted arithmetic mean.Linear regressions were performed to evaluate the associations of GOHI-FS with health and social-economic indicators.Results The GOHI-FS includes 5 first-level indicators,19 second-level indicators and 45 third-level indicators.There were 146 countries/territories enrolled for evaluation.The highest average score of first-level indicators was Nutrition(69.8)and the lowest was Government Support and Response(31.3).There was regional heterogeneity of GOHI-FS scores.Higher median scores with interquartile range(IQR)were shown in North America(median:76.1,IQR:75.5-76.7),followed by Europe and Central Asia(median:66.9,IQR:60.1-74.3),East Asia and the Pacific(median:60.6,IQR:55.5-68.7),Latin America and the Caribbean(median:60.2,IQR:57.8-65.0),Middle East and North Africa(median:56.6,IQR:52.0-62.8),South Asia(median:51.1,IQR:46.7-53.8),and sub-Saharan Africa(median:41.4,IQR:37.2-46.5).We also found significant associations between GOHI-FS and GDP per capita,socio-demographic index,health expenditure and life expectancy.Conclusions GOHI-FS is a potential assessment tool to understand the gaps in food security across countries/territories under the One Health concept.The pilot findings suggest notable gaps for sub-Saharan Africa in numerous aspects.Broad actions are needed globally to promote government support and response for food security.展开更多
Background Rare infectious diseases of poverty(rIDPs)involve more than hundreds of tropical diseases,which domi-nantly affect people living in impoverished and marginalized regions and fail to be prioritized in the gl...Background Rare infectious diseases of poverty(rIDPs)involve more than hundreds of tropical diseases,which domi-nantly affect people living in impoverished and marginalized regions and fail to be prioritized in the global health agenda.The neglect of rIDPs could impede the progress toward sustainable development.This study aimed to esti-mate the disease burden of rIDPs in 2021,which would be pivotal for setting intervention priorities and mobilizing resources globally.Methods Leveraging data from the Global Burden of Disease Study 2021,the study reported both numbers and age-standardized rates of prevalence,mortality,disability-adjusted life-years(DALYs),years lived with disability,and years of life lost of rIDPs with corresponding 95%uncertainty intervals(Uls)at global,regional,and national levels.The temporal trends between 1990 and 2021 were assessed by the joinpoint regression analysis.A Bayesian age-period-cohort model was used to project the disease burden for 2050.Results In 2021,there were 103.76 million(95%Ul:102.13,105.44 million)global population suffered from rIDPs with an age-standardized DALY rate of 58.44 per 100,000 population(95%Ul:42.92,77.26 per 100,000 population).From 1990 to 2021,the age-standardized DALY rates showed an average annual percentage change of-0.16%(95%confidence interval:-0.22,-0.11%).Higher age-standardized DALY rates were dominated in sub-Saharan Africa(126.35 per 100,000 population,95%Ul:91.04,161.73 per 100,000 population),South Asia(80.80 per 100,000 popula-tion,95%Ul:57.31,114.10 per 100,000 population),and countries with a low socio-demographic index.There was age heterogeneity in the DALY rates of rIDPs,with the population aged under 15 years being the most predominant.Females aged 15-49 years had four-times higher age-standardized DALY rates of rIDPs than males in the same age.The projections indicated a slight reduction in the disease burden of rIDPs by 2050.Conclusions There has been a slight reduction in the disease burden of rIDPs over the past three decades.Given that rIDPs mainly affect populations in impoverished regions,targeted health strategies and resource allocation are in great demand for these populations to further control rIDPs and end poverty in all its forms everywhere.展开更多
文摘Held on 8 May 2025,the 10th UN Multi-stakeholder Forum on Science,Technology and Innovation for the Sustainable Development Goals side event,titled"One Health for All:Synergistic Solutions Advancing SDG3 through Sustainable Science&Inclusive Innovation",convened global experts to explore integrated strategies for advancing human,animal,and environmental health within the 2030 Agenda.The event highlighted innovations like artificial intelligence(AI)-driven surveillance and low-carbon diagnostics,emphasizing equity and Sustainable Development Goals(SDGs)acceleration.One milestone was the launch of an expert consensus promoting the global One Health index(GOHI),a roadmap to align research and experimental development(R&D)with SDG3 targets.Discussions centered on three key issues covering:the One Health approach for SDGs,the role of GOHI as a scientific tool addressing data fragmentation and capacity disparities,and GOHI's potential to enhance cross-sectoral governance,exemplified by case studies from Japan,Cambodia,and Singapore.A consensus emerged to promote GOHI at the sub-national level,recognizing its value as a comprehensive,structured framework offering practical tools,data transformation capabilities,economic analysis,and global knowledge sharing,despite implementation challenges.Six actionable recommendations were proposed,focusing on strengthening institutional coordination,bridging data gaps,integrating GOHI into governance,piloting localized interventions,mobilizing funding,and building capacity through global partnerships.The event marked a significant step forward,positioning the One Health framework,facilitated by tools like GOHI,as essential for achieving the SDGs and ensuring a healthier,more sustainable future for all.
基金supported by the International Joint Laboratory on Tropical Diseases Control in Greater Mekong Subregion[grant number 21410750200]National Natural Science Foundation of China[grant number 82304102]+1 种基金Natural Science Foundation of Shanghai[grant number 23ZR1436200]Shanghai Science and Technology Development Foundation[grant number 22YF1421100,23YF1421200].
文摘Background:Emerging infectious diseases(EIDs)pose significant public health challenges due to increasing interactions between humans,animals,and the environment.The One Health framework,an interdisciplinary and collaborative approach,plays a critical role in the risk assessment of EIDs.The study aims to systematically review the risk assessment of EIDs in China under the One Health framework,covering policy support,monitoring and assessment systems,and implementation methods.Methods:Relevant literature and official documents between 1997 and 2024 were retrieved from Web of Science,PubMed,Scopus,China National Knowledge Infrastructure,Wan Fang,China Science and Technology Journal Database,and government websites.Data were synthesized to analyze progress,challenges,and gaps.Results:There were 43 academic studies and 31 official documents included in this review.The study found that risk assessment systems existed across human,animal,and environmental health sectors in China,and the government was advancing intelligent monitoring and fostering inter-departmental cooperation.However,several challenges remain in risk assessment of EIDs,including inadequate monitoring systems for unknown EIDs,limited capacity building for risk assessment in ecosystems and environmental systems,insufficiently detailed risk assessment guidance at the county level,and barriers to cross-sectoral information sharing at the international and county levels.Conclusion:The findings highlighted the need to enhance risk assessment of EIDs at the local level,expand the scope of disease surveillance including aquatic and wild animals,and strengthen inter-departmental data sharing to improve early warning capabilities under the One Health framework.
基金supported by Bill&Melinda Gates Foundation[grant number OPP1152504]International Joint Laboratory on Tropical Diseases Control in Greater Mekong Subregion[grant number 21410750200]+3 种基金National Natural Science Foundation of China[grant number 82304102]Natural Science Foundation of Shanghai[grant number 23ZR1436200]Shanghai Science and Technology Development Foundation[grant number 22YF1421100]Shanghai Science and Technology Development Foundation[grant number 23YF1421200].
文摘Background:Understanding the global burden of enteric infections is crucial for prioritizing control strategies for foodborne and waterborne diseases.This study aimed to assess the global burden of enteric infections in 2021 and identify risk factors from One Health aspects.Methods:Leveraging the Global Burden of Disease(GBD)2021 database,the incidence,disability-adjusted life years(DALYs),and deaths of enteric infections and the subtypes were estimated,including diarrheal diseases,typhoid and paratyphoid fever,invasive non-typhoidal Salmonella(iNTS)infections,and other intestinal infectious diseases.The estimates were quantified by absolute number,age-standardized incidence rate(ASIR),agestandardized mortality rate(ASMR)and age-standardized DALY rate with 95%uncertainty intervals(UIs).Thirteen pathogens and three risk factors associated with diarrheal diseases were analyzed.Results:In 2021,the global age-standardized DALY rate of enteric infections was 1020.15 per 100,000 popultion(95%UI:822.70-1259.39 per 100,000 population)with an estimated annual percentage change(EAPC)of-4.11%(95%confidence interval:-4.31%to-3.90%)in 1990-2021.A larger burden was observed in regions with lower socio-demographic index(SDI)levels.Diarrheal disease was the most serious subtype with Western Sub-Saharan Africa exhibiting the highest age-standardized DALY rate(2769.81 per 100,000 population,95%UI:1976.80-3674.41 per 100,000 population).Children under 5 and adults over 65 years suffered more from diarrheal diseases with the former experiencing the highest global age-standardized DALY rate(9382.46 per 100,000 population,95%UI:6771.76-13,075.12 per 100,000 population).Rotavirus remained the leading cause of diarrheal diseases despite a cross-year decline in the observed age-standardized DALY rate.Unsafe water,sanitation,and handwashing contributed most to the disease burden.Conclusion:The reduced burden of enteric infections suggested the effectiveness of previous control strategies;however,more efforts should be made in vulnerable regions and populations through a One Health approach.
基金supported by China Medical Board[No.20–365]Bill&Melinda Gates Foundation[No.INV-046218]the National Natural Science Foundation of China[No.72204160].
文摘Background:In the 21st century,as globalization accelerates and global public health crises occur,the One Health approach,guided by the holistic thinking of human-animal-environment and emphasizing interdisciplinary collaboration to address global health issues,has been strongly advocated by the international community.An immediate requirement exists for the creation of an assessment tool to foster One Health initiatives on both global and national scales.Methods:Built upon extensive expert consultations and dialogues,this follow-up study enhances the 2022 global One Health index(GOHI)indicator system.The GOHI framework is enriched by covering three indices,e.g.external drivers index(EDI),intrinsic drivers index(IDI),and core drivers index(CDI).The comprehensive indicator system incorporates 13 key indicators,50 indicators,and 170 sub I-indicators,utilizing a fuzzy analytic hierarchy process to ascertain the weight for each indicator.Weighted and summed,the EDI,IDI,and CDI scores contribute to the computation of the overall GOHI 2022 score.By comparing the ranking and the overall scores among the seven regions and across 160 countries/territories,we have not only derived an overall profile of the GOHI 2022 scores,but also assessed the GOHI framework.We also compared rankings of indicators and sub Iindicators to provide greater clarity on the strengths and weaknesses of each region within the One Health domains.Results:The GOHI 2022 performance reveals significant disparities between countries/territories ranged from 39.03 to 70.61.The global average score of the GOHI 2022 is 54.82.The average score for EDI,IDI,and CDI are 46.57,58.01,and 57.25,respectively.In terms of global rankings,countries from North America,Europe and Central Asia,East Asia and Pacific present higher scores.In terms of One Health domains of CDI,the lowest scores are observed in antimicrobial resistance(median:43.09),followed by food security(median:53.78),governance(median:54.77),climate change(median:64.12)and zoonotic diseases(median:69.23).Globally,the scores of GOHI vary spatially,with the highest score in North America while lowest in sub-Saharan Africa.In addition,evidence shows associations between the socio-demographic profile of countries/territories and their GOHI performance in certain One Health scenarios.Conclusion:The objective of GOHI is to guide impactful strategies for enhancing capacity building in One Health.With advanced technology and an annually updated database,intensifying efforts to refine GOHI's data-mining methodologies become imperative.The goal is to offer profound insights into disparities and progressions in practical One Health implementation,particularly in anticipation of future pandemics.
基金supported by Bill&Melinda Gates Foundation(No.INV-046218).
文摘Background:One Health is an integrated concept of health that aims to optimize the health of humans,animals,plants,and the environment.Identifying research gaps and specific expertise areas is important for understanding the role of One Health in practice.This information on One Health could be used to promote collaboration and research,inspire innovative ideas,and accelerate the translation of evidence-based practices into policies.Methods:We searched the Scopus database for publications related to One Health between 2012 and 2021 to extract bibliometric information and investigate the possibility of establishing a dedicated expertise database.We matched scholarly information using SciVal to exclude duplicate information and identify scholars’affiliations,countries,and academic profiles.Individual academic contributions to One Health were evaluated according to their citations,publication impact,publication type,and author contributions.Results:A total of 8,313 publications on One Health over a ten-year period were identified,with the number of publications increasing over time.The largest number of publications came from the United States and the United Kingdom.These countries also had the highest number of experts and a high level of international collaboration.We identified 500 scholars from 53 countries and 313 affiliations with a median Hirsch Index of 20 who could be included in a One Health expert database.These scientists had a median of six publications on One Health,with topics mostly focusing on dengue and antimicrobial resistance.Conclusion:A One Health information database could be used as a third-party reference for scholars,a source to track the ongoing academic progress,and support for active scholars in this field of research.
文摘Following publication of the original article[1],it was found the number of countries with identified One Health publications was incorrectly shown in Table 2,Supplementary data-Multimedia component 3(Table-S2),corresponding text and Fig.3,which should be corrected to 178.The number of countries with 500 One Health experts identified should be corrected to 53 in the abstract.
基金supported by the Hainan Province Science and Technology Special Fund(grant number ZDYF2022SHFZ321)National Natural Science Foundation of China(grant numbers 22104090,82102184)+2 种基金the Natural Science Foundation of Shanghai(grant numbers 22ZR1436200,23ZR1436800)Shanghai Municipal Health Commission of China(grant number 2024QN083)Shanghai Jiao Tong University School of Medicine(grant number WK2406).
文摘Emerging infectious diseases(EIDs)pose a significant threat to public health.Effective surveillance and early warning systems that monitor EIDs in a timely manner are crucial for their control.Given that more than half of EIDs are zoonotic,traditional integrated surveillance systems remain inadequate.Despite recent advances in integrated systems in China,there are few systemic reviews on the integrated surveillance and early warning system of EIDs at community level,particularly under the One Health framework.Here,this systematic review summarizes the current status of surveillance advances in China,including the multi-trigger integrated monitor system.It also highlights the mechanisms for embedding the One Health approach into local policy and practice,while identifying challenges and opportunities for improvement.Additionally,guidelines and recommendations are proposed to optimize the integration of multi-sectoral,multi-level and interdisciplinary cooperation at the human-animal-environment interface.
文摘Background Food systems instantiate the complex interdependencies across humans,physical environments,and other organisms.Applying One Health approaches for agri-food system transformation,which adopts integrated and unifying approaches to optimize the overall health of humans,animals,plants,and environments,is crucial to enhance the sustainability of food systems.This study develops a potential assessment tool,named the global One Health index-Food Security(GOHI-FS),aiming to evaluate food security performance across countries/territories from One Health perspective and identify relevant gaps that need to be improved for sustainable food systems.Methods We comprehensively reviewed existing frameworks and elements of food security.The indicator framework of GOHI-FS was conceptualized following the structure-process-outcome model and confirmed by expert advisory.Publicly available data in 2020 was collected for each indicator.The weighting strategy was determined by the Fuzzy Analytical Hierarchy Process.The data for each indicator was normalized and aggregated by weighted arithmetic mean.Linear regressions were performed to evaluate the associations of GOHI-FS with health and social-economic indicators.Results The GOHI-FS includes 5 first-level indicators,19 second-level indicators and 45 third-level indicators.There were 146 countries/territories enrolled for evaluation.The highest average score of first-level indicators was Nutrition(69.8)and the lowest was Government Support and Response(31.3).There was regional heterogeneity of GOHI-FS scores.Higher median scores with interquartile range(IQR)were shown in North America(median:76.1,IQR:75.5-76.7),followed by Europe and Central Asia(median:66.9,IQR:60.1-74.3),East Asia and the Pacific(median:60.6,IQR:55.5-68.7),Latin America and the Caribbean(median:60.2,IQR:57.8-65.0),Middle East and North Africa(median:56.6,IQR:52.0-62.8),South Asia(median:51.1,IQR:46.7-53.8),and sub-Saharan Africa(median:41.4,IQR:37.2-46.5).We also found significant associations between GOHI-FS and GDP per capita,socio-demographic index,health expenditure and life expectancy.Conclusions GOHI-FS is a potential assessment tool to understand the gaps in food security across countries/territories under the One Health concept.The pilot findings suggest notable gaps for sub-Saharan Africa in numerous aspects.Broad actions are needed globally to promote government support and response for food security.
基金supported by International Joint Laboratory on Tropical Diseases Control in Greater Mekong Subregion(21410750200)National Natural Science Foundation of China(82304102)+2 种基金Natural Science Foundation of Shanghai(23ZR1436200)Shanghai Science and Technology Development Foundation(22YF1421100,23YF1421200)the Bill&Melinda Gates Foundation.The Funders had no role in the study design or in the collection,analysis,and interpretation of the data,writing of the report,or decision to submit the article for publication.
文摘Background Rare infectious diseases of poverty(rIDPs)involve more than hundreds of tropical diseases,which domi-nantly affect people living in impoverished and marginalized regions and fail to be prioritized in the global health agenda.The neglect of rIDPs could impede the progress toward sustainable development.This study aimed to esti-mate the disease burden of rIDPs in 2021,which would be pivotal for setting intervention priorities and mobilizing resources globally.Methods Leveraging data from the Global Burden of Disease Study 2021,the study reported both numbers and age-standardized rates of prevalence,mortality,disability-adjusted life-years(DALYs),years lived with disability,and years of life lost of rIDPs with corresponding 95%uncertainty intervals(Uls)at global,regional,and national levels.The temporal trends between 1990 and 2021 were assessed by the joinpoint regression analysis.A Bayesian age-period-cohort model was used to project the disease burden for 2050.Results In 2021,there were 103.76 million(95%Ul:102.13,105.44 million)global population suffered from rIDPs with an age-standardized DALY rate of 58.44 per 100,000 population(95%Ul:42.92,77.26 per 100,000 population).From 1990 to 2021,the age-standardized DALY rates showed an average annual percentage change of-0.16%(95%confidence interval:-0.22,-0.11%).Higher age-standardized DALY rates were dominated in sub-Saharan Africa(126.35 per 100,000 population,95%Ul:91.04,161.73 per 100,000 population),South Asia(80.80 per 100,000 popula-tion,95%Ul:57.31,114.10 per 100,000 population),and countries with a low socio-demographic index.There was age heterogeneity in the DALY rates of rIDPs,with the population aged under 15 years being the most predominant.Females aged 15-49 years had four-times higher age-standardized DALY rates of rIDPs than males in the same age.The projections indicated a slight reduction in the disease burden of rIDPs by 2050.Conclusions There has been a slight reduction in the disease burden of rIDPs over the past three decades.Given that rIDPs mainly affect populations in impoverished regions,targeted health strategies and resource allocation are in great demand for these populations to further control rIDPs and end poverty in all its forms everywhere.
