OBJECTIVE:This study aims to explore the value of magnetic resonance native T1 mapping technology in diagnosing fulminant myocarditis(FM),as there is currently a lack of reliable imaging features for identifying this ...OBJECTIVE:This study aims to explore the value of magnetic resonance native T1 mapping technology in diagnosing fulminant myocarditis(FM),as there is currently a lack of reliable imaging features for identifying this condition in clinical practice.METHODS:A total of 112 patients clinically diagnosed with myocarditis and who underwent cardiac MRI scans from June 2019 to June 2022 were included in the study.The patients were divided into two groups based on the diagnostic criteria of FM:the FM group(n=38)and the non‑FM group(n=74).In addition,a control group(n=38)consisting of healthy volunteers matching the age and gender of the study group was also collected.Cardiac magnetic resonance(CMR)results and relevant clinical data were collected from patients.Analysis of variance and rank sum tests were used to examine the correlation between different groups.The results showed a statistically significant difference(P<0.001)in the native T1 mapping values between the two groups.The receiver operating characteristic curve analysis indicated good diagnostic efficacy(area under the curve=0.872),with a cutoff value>1315.0 ms.The sensitivity and specificity were 81.6%and 87.8%,respectively.There was no statistically significant difference in EDV,end‑diastolic volume index,end‑systolic volume(ESV),stroke volume,stroke volume index,cardiac output,cardiac index,and left ventricular mass(LVM)index between the two groups.However,there was a statistically significant difference in ESV index and LVM(P<0.001).CONCLUSION:The utilization of native T1 mapping in CMR imaging can be a valuable tool for differentiating between FM and non‑FM.This technology can also aid in the early clinical diagnosis of FM,providing important insights for medical professionals.展开更多
基金supported by grants from the Fujian Provincial Health Science and Technology Plan Project(2023QNB004)Xiamen Natural Science Foundation Project(3502Z202373114)+2 种基金Xiamen Medical and Health Guidance Project(3502Z20224ZD1194)Xiamen Natural Science Foundation Project(3502Z202372090)the Youth Research Fund Project of Xiang’an Hospital of Xiamen University(XM02060001).
文摘OBJECTIVE:This study aims to explore the value of magnetic resonance native T1 mapping technology in diagnosing fulminant myocarditis(FM),as there is currently a lack of reliable imaging features for identifying this condition in clinical practice.METHODS:A total of 112 patients clinically diagnosed with myocarditis and who underwent cardiac MRI scans from June 2019 to June 2022 were included in the study.The patients were divided into two groups based on the diagnostic criteria of FM:the FM group(n=38)and the non‑FM group(n=74).In addition,a control group(n=38)consisting of healthy volunteers matching the age and gender of the study group was also collected.Cardiac magnetic resonance(CMR)results and relevant clinical data were collected from patients.Analysis of variance and rank sum tests were used to examine the correlation between different groups.The results showed a statistically significant difference(P<0.001)in the native T1 mapping values between the two groups.The receiver operating characteristic curve analysis indicated good diagnostic efficacy(area under the curve=0.872),with a cutoff value>1315.0 ms.The sensitivity and specificity were 81.6%and 87.8%,respectively.There was no statistically significant difference in EDV,end‑diastolic volume index,end‑systolic volume(ESV),stroke volume,stroke volume index,cardiac output,cardiac index,and left ventricular mass(LVM)index between the two groups.However,there was a statistically significant difference in ESV index and LVM(P<0.001).CONCLUSION:The utilization of native T1 mapping in CMR imaging can be a valuable tool for differentiating between FM and non‑FM.This technology can also aid in the early clinical diagnosis of FM,providing important insights for medical professionals.
