PURPOSE: This study was designed to look for significant correlations between location of early colorectal cancer, distance from muscularis mucosae to muscularis propria, and the frequency of lymph node metastasis. ME...PURPOSE: This study was designed to look for significant correlations between location of early colorectal cancer, distance from muscularis mucosae to muscularis propria, and the frequency of lymph node metastasis. METHODS: A total of 166 early colorectal cancers, including 67 surgically resected lesions, were evaluated. The cancers were divided into two groups: metastatic and nonmetastatic. Cancer lesions were further subtyped at the fold-top or fold-bottom. Macroscopic classifications and histology were performed. Absolute invasive depth and distance from muscularis mucosae to muscularis propria was measured. Multivariate analysis was used to assess relationships among the variables. RESULTS: The percentage of polypoid cancer lesions at fold-bottom was higher than at fold-top (74.5 vs. 51.8 percent), whereas flat-type cancer lesions at fold-bottom occurred less often than at fold-top (8.2 vs. 30.4 percent). Logistic regression showed that deep absolute invasive depth, lymphatic and vessel invasion,and cancer location (at fold-bottom) were the significant risk factors for early colorectal cancers leading to lymph-node metastasis. The distance from muscularis mucosae to muscularis propria with lymph node metastasis (1,396.7 ±728.4 μm) was shorter than without lymph node metastasis (3,533.9 ±2,507.8 μm; P < 0.01). Multivariate analysis showed that distance from muscularis mucosae to muscularis propria was a statistically significant factor for early colorectal cancers leading to lymph node metastasis (P = 0.0054). CONCLUSIONS:We conclude that early colorectal cancers at the fold-top or with a long distance from muscularis mucosae to muscularis propria have less tendency to metastasize to lymph nodes. Clinically, these results provide evidence of a new indicator of endoscopic mucosal resection for early colorectal cancers at the fold-top.展开更多
During the upward period of solar cycle 23, the imaging riometer at Zhongshan, Antarctica (geomag. lat. 74.5°S) was used to study the solar proton events and the X-ray solar flares which are associated with the a...During the upward period of solar cycle 23, the imaging riometer at Zhongshan, Antarctica (geomag. lat. 74.5°S) was used to study the solar proton events and the X-ray solar flares which are associated with the absorption events. In our study, the relationship between the absorption intensity and X-ray flux is found in a power form which is consistent with the theoretical result. The imaging riometer absorption data at Ny-Alesund, Svalbard reconfirm the above relationship. We also argue that only M-class flares can generate a significant daytime absorption.展开更多
Vacuum-UV Photoelectron Spectroscopy (UPS) has attracted increasing attention since it was demonstrated to be a useful method for obtaining detailed information on electron structure of molecules, and valence-band and...Vacuum-UV Photoelectron Spectroscopy (UPS) has attracted increasing attention since it was demonstrated to be a useful method for obtaining detailed information on electron structure of molecules, and valence-band and conduction-band of solid and crystal. A lot of investigations on both gas and solid by UPS have been reported, but only few of them on polymers. We have reported the characterization of vinyl polymers using UPS. The object of the present report is展开更多
文摘PURPOSE: This study was designed to look for significant correlations between location of early colorectal cancer, distance from muscularis mucosae to muscularis propria, and the frequency of lymph node metastasis. METHODS: A total of 166 early colorectal cancers, including 67 surgically resected lesions, were evaluated. The cancers were divided into two groups: metastatic and nonmetastatic. Cancer lesions were further subtyped at the fold-top or fold-bottom. Macroscopic classifications and histology were performed. Absolute invasive depth and distance from muscularis mucosae to muscularis propria was measured. Multivariate analysis was used to assess relationships among the variables. RESULTS: The percentage of polypoid cancer lesions at fold-bottom was higher than at fold-top (74.5 vs. 51.8 percent), whereas flat-type cancer lesions at fold-bottom occurred less often than at fold-top (8.2 vs. 30.4 percent). Logistic regression showed that deep absolute invasive depth, lymphatic and vessel invasion,and cancer location (at fold-bottom) were the significant risk factors for early colorectal cancers leading to lymph-node metastasis. The distance from muscularis mucosae to muscularis propria with lymph node metastasis (1,396.7 ±728.4 μm) was shorter than without lymph node metastasis (3,533.9 ±2,507.8 μm; P < 0.01). Multivariate analysis showed that distance from muscularis mucosae to muscularis propria was a statistically significant factor for early colorectal cancers leading to lymph node metastasis (P = 0.0054). CONCLUSIONS:We conclude that early colorectal cancers at the fold-top or with a long distance from muscularis mucosae to muscularis propria have less tendency to metastasize to lymph nodes. Clinically, these results provide evidence of a new indicator of endoscopic mucosal resection for early colorectal cancers at the fold-top.
基金the National Natural Science Foundation ofChina (Grant No. 49639160), the major project of Chinese Academy of Sciences (Grant No. KJ951-1-305) and the Oceanic Youth Foundation of State Oceanic Administration (Grant No. 98605).
文摘During the upward period of solar cycle 23, the imaging riometer at Zhongshan, Antarctica (geomag. lat. 74.5°S) was used to study the solar proton events and the X-ray solar flares which are associated with the absorption events. In our study, the relationship between the absorption intensity and X-ray flux is found in a power form which is consistent with the theoretical result. The imaging riometer absorption data at Ny-Alesund, Svalbard reconfirm the above relationship. We also argue that only M-class flares can generate a significant daytime absorption.
文摘Vacuum-UV Photoelectron Spectroscopy (UPS) has attracted increasing attention since it was demonstrated to be a useful method for obtaining detailed information on electron structure of molecules, and valence-band and conduction-band of solid and crystal. A lot of investigations on both gas and solid by UPS have been reported, but only few of them on polymers. We have reported the characterization of vinyl polymers using UPS. The object of the present report is
