The effect of depositional facies and diagenesis on the reservoir potential of the Sakesar limestone has been assessed through core plug porosity and permeability data,scanning electron microscope(SEM),and petrographi...The effect of depositional facies and diagenesis on the reservoir potential of the Sakesar limestone has been assessed through core plug porosity and permeability data,scanning electron microscope(SEM),and petrographic study in three stratigraphic sections(Karuli,Badshah Pur,and Sardhai)of Central Salt Range.Field observations reveal three lithofacies:thin-bedded limestone with shale intercalation,thick-bedded nodular limestone,and highly fractured limestone.Based on a petrographic study,six microfacies have been identified:bioclastic mudstone facies(SKF-1),Lockhartia-nummulitic wackestone facies(SKF-2),Assilina-Alveolina packstone facies(SKF-3),Lockhartia-nummulitic packstone facies(SKF-4),Alveolina grainstone facies(SKF-5),and nummulitic grainstone facies(SKF-6).The Sakesar limestone shows various diagenetic changes such as compaction,dissolution,dolomitization,cementation,and fracturing,resulting in different types of pores.Two reservoir zones are identified in the Sakesar limestone:a mud-dominated reservoir in an outer ramp setting with interparticle and micropores and a bioclastic grain-dominated facies in an inner ramp setting with intraskeletal and fracture porosity.The porosity and permeability of grain-dominated facies(8%-30%and 0.8-8 mD)are higher than mud-dominated facies(4%-15%and 0.5-4 mD)due to intraskeletal/intraparticle pores and dolomitization.展开更多
In the field of precision healthcare,where accurate decision-making is paramount,this study underscores the indispensability of eXplainable Artificial Intelligence(XAI)in the context of epilepsy management within the ...In the field of precision healthcare,where accurate decision-making is paramount,this study underscores the indispensability of eXplainable Artificial Intelligence(XAI)in the context of epilepsy management within the Internet of Medical Things(IoMT).The methodology entails meticulous preprocessing,involving the application of a band-pass filter and epoch segmentation to optimize the quality of Electroencephalograph(EEG)data.The subsequent extraction of statistical features facilitates the differentiation between seizure and non-seizure patterns.The classification phase integrates Support Vector Machine(SVM),K-Nearest Neighbor(KNN),and Random Forest classifiers.Notably,SVM attains an accuracy of 97.26%,excelling in the precision,recall,specificity,and F1 score for identifying seizures and non-seizure instances.Conversely,KNN achieves an accuracy of 72.69%,accompanied by certain trade-offs.The Random Forest classifierstands out with a remarkable accuracy of 99.89%,coupled with an exceptional precision(99.73%),recall(100%),specificity(99.80%),and F1 score(99.86%),surpassing both SVM and KNN performances.XAI techniques,namely Local Interpretable ModelAgnostic Explanations(LIME)and SHapley Additive exPlanation(SHAP),enhance the system’s transparency.This combination of machine learning and XAI not only improves the reliability and accuracy of the seizure detection system but also enhances trust and interpretability.Healthcare professionals can leverage the identified important features and their dependencies to gain deeper insights into the decision-making process,aiding in informed diagnosis and treatment decisions for patients with epilepsy.展开更多
Pediatric cardiomyopathies are clinically heterogeneous heart muscle disorders that are responsible for significant morbidity and mortality. Phenotypes include hypertrophic cardiomyopathy, dilated cardiomyopathy, rest...Pediatric cardiomyopathies are clinically heterogeneous heart muscle disorders that are responsible for significant morbidity and mortality. Phenotypes include hypertrophic cardiomyopathy, dilated cardiomyopathy, restrictive cardiomyopathy, left ventricular noncompaction and arrhythmogenic right ventricular cardiomyopathy. There is substantial evidence for a genetic contribution to pediatric cardiomyopathy. To date, more than 100 genes have been implicated in cardiomyopathy, but comprehensive genetic diagnosis has been problematic because of the large number of genes, the private nature of mutations, and difficulties in interpreting novel rare variants. This review will focus on current knowledge on the genetic etiologies of pediatric cardiomyopathy and their diagnostic relevance in clinical settings. Recent developments in sequencing technologies are greatly impacting the pace of gene discovery and clinical diagnosis. Understanding the genetic basis for pediatric cardiomyopathy and establishing genotypephenotype correlations may help delineate the molecular and cellular events necessary to identify potential novel therapeutic targets for heart muscle dysfunction in children.展开更多
We aimed to find the toxicological impacts of Cd, Pb and Zn in single dozes and in combinations on Purslane (Portulaca oleracea) seedling. The Pursolane seedlings? grown in pots in a green house were treated with diff...We aimed to find the toxicological impacts of Cd, Pb and Zn in single dozes and in combinations on Purslane (Portulaca oleracea) seedling. The Pursolane seedlings? grown in pots in a green house were treated with different soil treatments spiked (mg/kg) with Pb (300, 400 and 500), Cd (0.5, 1 and 1.5), and Zn (250, 500, 700) alone and then in specified combinations/concentrations i.e., Cd/Pb (0.5/300, 1/400, 1.5/500), Cd/Zn (0.5/250, 1/500, 1.5/700) and Pb/Zn (300/250, 400/500, 500/ 700). The results indicated that increasing concentrations of the studied HMs in seedlings tissues significantly (p P. oleracea seedling, compared to Pb and Zn. Roots of P. oleracea seedlings were more sensitive to the studied HMs in comparison with shoot. The uptake patterns showed antagonistic impacts on each other and were reflected in response to growth parameters. The combine toxicities of Cd, Pb and Zn (Cd/Pb, Cd/Zn and Pb/Zn) were more than the toxicity due to single dose of each element but less than their additive sums.展开更多
The present work has been accomplished to carry out a detailed study of the characteristics of the Early Jurassic Datta Formation of Trans-Indus Ranges, Pakistan. The discovery of Saib well-1 (Gas and condensate disco...The present work has been accomplished to carry out a detailed study of the characteristics of the Early Jurassic Datta Formation of Trans-Indus Ranges, Pakistan. The discovery of Saib well-1 (Gas and condensate discovery from Jurassic limestone) in the study basin takes an active interest in carrying out extensive exploration activities in the same basin. Jurassic rocks especially Datta Sandstone and Samana Suk Limestone are acting as good reservoirs. The study unit consists of variegated sandstone interbedded with siltstone, carbonaceous clay, and shale and coal stringer. For the current work, two stratigraphic sections (Pezu and Abbo Wanda) have been measured. To examine its sedimentology, depositional environment, diagenetic settings, and reservoir characteristics, a detailed study was conducted and various laboratory techniques have been utilized. About 95 rock samples from the bottom to the top of both sections were collected, and 50 rock samples have been selected for thin section analysis and were examined under a polarizing microscope to show their mineralogical composition, diagenesis, and their reservoir characteristics. XRD (X-ray diffraction), Cathodoluminescence (CL), SEM (Scanning electron microscope) with EDS (Energy-dispersive spectroscope), and Core plug porosity and permeability analysis have been used to interpret its chemical and mineralogical composition and its reservoir characteristics, respectively. Based on field observations and thin section analysis, four depositional facies and six lithofacies have been established. The sedimentary structures, depositional facies, and lithofacies indicate that Datta Formation was deposited in a deltaic environment. Compactions, cementation, fracturing and dissolution can greatly affect the quality of reservoir rock. Based on thin section and SEM analysis, large numbers of primary pores, fracture and secondary pores were observed and connectivity between the pores is good, and at some places, these pores were filled through the authigenic clay minerals like kaolinite, mixed layers illite/smectite and chlorite that influences the reservoir characteristics. Primary pores (thin section) and secondary pores (dissolution pores) and core plug porosity and permeability data (porosity 13.23%-26.89% and permeability 0.12 to 149 mD) shows that Datta Formation has a good reservoir quality.展开更多
This is a case report of a patient who presented to the Aga Khan University Hospital with generalized abdominal lymphadenopathy and high-grade fever.Due to ambiguous clinical findings,which were suggestive of either a...This is a case report of a patient who presented to the Aga Khan University Hospital with generalized abdominal lymphadenopathy and high-grade fever.Due to ambiguous clinical findings,which were suggestive of either abdominal tuberculosis,or a lymphoma,the patient was started on empirical anti-tuberculous treatment due to the endemicity of tuberculosis in this region.The blood culture reports,however,were reported to grow colonies of Salmonella paratyphi A;thus the diagnosis of the patient was changed to enteric fever,and the patient improved on the subsequently started therapy of ceftriaxone 2000 mg bid.To the best of our knowledge,this is the first reported case of a patient suffering from enteric fever whose primary clinical findings were abdominal lymphadenopathy and fever.展开更多
Persistent organic pollutants(POPs)persisting in the environment,which accumulate in human and animal tissue and bio-magnify in food-chains,would have significant impacts on human health and the environment.Thus,the p...Persistent organic pollutants(POPs)persisting in the environment,which accumulate in human and animal tissue and bio-magnify in food-chains,would have significant impacts on human health and the environment.Thus,the present study was designed to investigate the accumulation of organic pollutants in prawn from streams of Sialkot,Pakistan.Fresh water prawn Macrobrachium lamarrei was captured from streams of study area.Samples were prepared for extraction of selected organic pollutants and then analyzed through gas chromatograph-electron capture detector(GC-ECD).Results of current study showed that five pesticide residues,i.e.,B-HCH,Lindane,DDD,2,4-DDT and 4,4-DDT were detected in composite prawn sample.The rest of POPs residues were not found in prawn.The ratio of a-HCH/γ-HCH indicated an input of technical HCH and long range transport,while the ratio of DDT/(DDD+DDE)showed recent use of DDT to the study area.The high values of TEC-HQ and PEC-HQ of POPs in the studied prawn samples depicted risk posed to health.展开更多
Power Line Communications-Artificial Intelligence of Things(PLC-AIo T)combines the low cost and high coverage of PLC with the learning ability of Artificial Intelligence(AI)to provide data collection and transmission ...Power Line Communications-Artificial Intelligence of Things(PLC-AIo T)combines the low cost and high coverage of PLC with the learning ability of Artificial Intelligence(AI)to provide data collection and transmission capabilities for PLC-AIo T devices in smart parks.With the development of smart parks,their emerging services require secure and accurate time synchronization of PLC-AIo T devices.However,the impact of attackers on the accuracy of time synchronization cannot be ignored.To solve the aforementioned problems,we propose a tampering attack-aware Deep Q-Network(DQN)-based time synchronization algorithm.First,we construct an abnormal clock source detection model.Then,the abnormal clock source is detected and excluded by comparing the time synchronization information between the device and the gateway.Finally,the proposed algorithm realizes the joint guarantee of high accuracy and low delay for PLC-AIo T in smart parks by intelligently selecting the multi-clock source cooperation strategy and timing weights.Simulation results show that the proposed algorithm has better time synchronization delay and accuracy performance.展开更多
Plant quality can directly and indirectly affect the third trophic level. The predation by all the instars of green lacewing, Chrysoperla carnea （S.） （Neuroptera： Chrysopidae） on the cereal aphids, Rhopalosiphum ...Plant quality can directly and indirectly affect the third trophic level. The predation by all the instars of green lacewing, Chrysoperla carnea （S.） （Neuroptera： Chrysopidae） on the cereal aphids, Rhopalosiphum padi （L.）, and Sitobion avenae （F.） at varying nitrogen fertilizer levels was calculated under laboratory conditions. Wheat plants were grown on four nitrogen fertilizer levels and aphids were fed on these plants and subsequently offered as food to the C. carnea. Aphid densities of 10, 30, and 90 were offered to first, second, and third instar larvae of green lacewing. Increased nitrogen application improved nitrogen contents of the plants and also the body weight of cereal aphids feeding on them. Aphid consumption by green lacewings was reduced with the increase in nitrogen content in the host plants of aphids. Predation of both aphid species by first, second, and third instars larvae of C. carnea was highest on aphids reared on plants with the lowest rate of fertilization, suggesting a compensatory consumption to overcome reduced biomass （lower aphid size）. Total biomass devoured by C. carnea on all nitrogen fertilizer treatments was not statistically different. Additionally, the heavier host prey influenced by the plant nutrition had an effect on the life history characteristics of green lacewings. The larval duration, pupal weight, pupal duration, fecundity, and male and female longevity were significantly affected by the level of nitrogen fertilization to the aphid＇s host plants, except for pupal duration when fed on S. avenae. This study showed that quantity of prey supplied to the larvae affects the prey consumption and thereafter the life history characteristics of green lacewings.展开更多
Pre-harvest sprouting in wheat is the germination of seeds within the spikes when rains occur after or during grain ripening, which occurs commonly in the barani tract of Pakistan. Therefore, 10 cultivars and five adv...Pre-harvest sprouting in wheat is the germination of seeds within the spikes when rains occur after or during grain ripening, which occurs commonly in the barani tract of Pakistan. Therefore, 10 cultivars and five advanced lines of spring bread wheat were evaluated for pre-harvest sprouting resistance. After natural rainfall,seeds were immediately collected from the wet spikes and tested for germinating ability. Three different germination tests were applied to hand-threshed seed:(1) spikes threshed on the day of sampling and germination tested immediately,(2) spikes threshed on the day of sampling and germination tested 1 week later, and(3) spikes threshed 1 week after sampling and germination test immediately after threshing. Seeds and spikes kept for 1 week were place on blotting paper at room temperature.Cultivars BARS-09, 09 FJ17, Doukkala-12, NARC-09 and Ouassou-20 exhibited higher sprouting resistance while other genotypes were susceptible to pre-harvest sprouting in each of the three tests. A diallel crossing was conducted with six susceptible and two resistant genotypes to assess the genetic behavior of pre-harvest sprouting resistance.The combining ability(CA) demonstrated a higher proportion of additive genetic effects for sprouting resistance, because of higher variance of general and specific CA for both parameters under study. Doukkala-12 and BARS-09 showed increased pre-harvest sprouting resistance in their F1 descendants.展开更多
Availability of mobile laboratories can facilitate rapid on-spot detection of pathogens,monitor its presence in certain populations and inform health authorities to take immediate remedial measures.Currently available...Availability of mobile laboratories can facilitate rapid on-spot detection of pathogens,monitor its presence in certain populations and inform health authorities to take immediate remedial measures.Currently available biosafety and biosecurity guidelines and policies may not completely articulate the increased demand to manage mobile units in infectious disease outbreaks in remote parts of the country for rapid diagnosis,and also allows research and epidemiological study take place appropriately.The main objective of this study is to evaluate the current limitations and develop and implement biosafety and biosecurity guidelines as well as the protocols for operations,security,and response plan of mobile biosafety level 2 laboratories and their deployment.Keeping in view the sensitivity of it,a comprehensive plan was developed to address it in view of Global Health Security framework.Biosafety and biosecurity protocols were developed including Risk Assessment Tool(RAT)fitting the needs and strengthen the diagnostic and epidemiological capacity in the field covering remote parts of country to fill the gaps observed during the COVID-19 pandemic.Currently the biosafety and biosecurity best practices guidelines and biosecurity policy and regulations are directed mostly towards static laboratories.A biosafety and biosecurity manual developed to adopt and meet the requirements for MBSL 2.For acute health infectious threats including the COVID-19 outbreak and other epidemics,rapid diagnosis can curb and mitigate the problem before it gets out of its boundaries creating significant health risks for the public and economy.The deployment of mobile laboratories will certainly help in curbing these catastrophes.展开更多
The response surface technique was applied to produce synbiotic yogurt containing Lacticaseibacillus rhamnosusand aloe vera gel (AVG) with high functionality (antioxidant and antimicrobial characters), superior physic...The response surface technique was applied to produce synbiotic yogurt containing Lacticaseibacillus rhamnosusand aloe vera gel (AVG) with high functionality (antioxidant and antimicrobial characters), superior physicochemicalproperties, and desirable sensory attributes. The experiments were planned around a central composite design (CCD)with two independent variables: AVG concentration (0–5%, w/w) and storage time (1–28 days). The AVG concentrationand storage time significantly improved the viability of L. rhamnosus up to 7.9 cfu/g during the shelf life which isa practical limit for a probiotic. It enhanced the yogurt’s antioxidant and antipathogenic activity, proteolytic content,water-holding capacity, and sensory aspects. High concentrations of AVG reduced the yogurt’s desirable texturalaspects (hardness and gumminess) except for firmness and adhesiveness and to some degree the sensory propertiesas well. The results showed that adding 5% AVG to probiotic yogurt produced a functional food with 68% desirabilitythat retained its beneficial properties for at least 14 days under refrigerated storage.展开更多
基金funded by the National Key Research and Development Program of China(Nos.2022YFF0801202,2022YFF0801200)。
文摘The effect of depositional facies and diagenesis on the reservoir potential of the Sakesar limestone has been assessed through core plug porosity and permeability data,scanning electron microscope(SEM),and petrographic study in three stratigraphic sections(Karuli,Badshah Pur,and Sardhai)of Central Salt Range.Field observations reveal three lithofacies:thin-bedded limestone with shale intercalation,thick-bedded nodular limestone,and highly fractured limestone.Based on a petrographic study,six microfacies have been identified:bioclastic mudstone facies(SKF-1),Lockhartia-nummulitic wackestone facies(SKF-2),Assilina-Alveolina packstone facies(SKF-3),Lockhartia-nummulitic packstone facies(SKF-4),Alveolina grainstone facies(SKF-5),and nummulitic grainstone facies(SKF-6).The Sakesar limestone shows various diagenetic changes such as compaction,dissolution,dolomitization,cementation,and fracturing,resulting in different types of pores.Two reservoir zones are identified in the Sakesar limestone:a mud-dominated reservoir in an outer ramp setting with interparticle and micropores and a bioclastic grain-dominated facies in an inner ramp setting with intraskeletal and fracture porosity.The porosity and permeability of grain-dominated facies(8%-30%and 0.8-8 mD)are higher than mud-dominated facies(4%-15%and 0.5-4 mD)due to intraskeletal/intraparticle pores and dolomitization.
文摘In the field of precision healthcare,where accurate decision-making is paramount,this study underscores the indispensability of eXplainable Artificial Intelligence(XAI)in the context of epilepsy management within the Internet of Medical Things(IoMT).The methodology entails meticulous preprocessing,involving the application of a band-pass filter and epoch segmentation to optimize the quality of Electroencephalograph(EEG)data.The subsequent extraction of statistical features facilitates the differentiation between seizure and non-seizure patterns.The classification phase integrates Support Vector Machine(SVM),K-Nearest Neighbor(KNN),and Random Forest classifiers.Notably,SVM attains an accuracy of 97.26%,excelling in the precision,recall,specificity,and F1 score for identifying seizures and non-seizure instances.Conversely,KNN achieves an accuracy of 72.69%,accompanied by certain trade-offs.The Random Forest classifierstands out with a remarkable accuracy of 99.89%,coupled with an exceptional precision(99.73%),recall(100%),specificity(99.80%),and F1 score(99.86%),surpassing both SVM and KNN performances.XAI techniques,namely Local Interpretable ModelAgnostic Explanations(LIME)and SHapley Additive exPlanation(SHAP),enhance the system’s transparency.This combination of machine learning and XAI not only improves the reliability and accuracy of the seizure detection system but also enhances trust and interpretability.Healthcare professionals can leverage the identified important features and their dependencies to gain deeper insights into the decision-making process,aiding in informed diagnosis and treatment decisions for patients with epilepsy.
基金Supported by The Children’s Cardiomyopathy FoundationCincinnati Children’s Hospital’s Clinical and Translational Science Award,No.NIH-ULl RR026314(Ware SM)and AHA Postdoctoral Fellowship Award,No.12POST10370002(Tariq M)
文摘Pediatric cardiomyopathies are clinically heterogeneous heart muscle disorders that are responsible for significant morbidity and mortality. Phenotypes include hypertrophic cardiomyopathy, dilated cardiomyopathy, restrictive cardiomyopathy, left ventricular noncompaction and arrhythmogenic right ventricular cardiomyopathy. There is substantial evidence for a genetic contribution to pediatric cardiomyopathy. To date, more than 100 genes have been implicated in cardiomyopathy, but comprehensive genetic diagnosis has been problematic because of the large number of genes, the private nature of mutations, and difficulties in interpreting novel rare variants. This review will focus on current knowledge on the genetic etiologies of pediatric cardiomyopathy and their diagnostic relevance in clinical settings. Recent developments in sequencing technologies are greatly impacting the pace of gene discovery and clinical diagnosis. Understanding the genetic basis for pediatric cardiomyopathy and establishing genotypephenotype correlations may help delineate the molecular and cellular events necessary to identify potential novel therapeutic targets for heart muscle dysfunction in children.
文摘We aimed to find the toxicological impacts of Cd, Pb and Zn in single dozes and in combinations on Purslane (Portulaca oleracea) seedling. The Pursolane seedlings? grown in pots in a green house were treated with different soil treatments spiked (mg/kg) with Pb (300, 400 and 500), Cd (0.5, 1 and 1.5), and Zn (250, 500, 700) alone and then in specified combinations/concentrations i.e., Cd/Pb (0.5/300, 1/400, 1.5/500), Cd/Zn (0.5/250, 1/500, 1.5/700) and Pb/Zn (300/250, 400/500, 500/ 700). The results indicated that increasing concentrations of the studied HMs in seedlings tissues significantly (p P. oleracea seedling, compared to Pb and Zn. Roots of P. oleracea seedlings were more sensitive to the studied HMs in comparison with shoot. The uptake patterns showed antagonistic impacts on each other and were reflected in response to growth parameters. The combine toxicities of Cd, Pb and Zn (Cd/Pb, Cd/Zn and Pb/Zn) were more than the toxicity due to single dose of each element but less than their additive sums.
文摘The present work has been accomplished to carry out a detailed study of the characteristics of the Early Jurassic Datta Formation of Trans-Indus Ranges, Pakistan. The discovery of Saib well-1 (Gas and condensate discovery from Jurassic limestone) in the study basin takes an active interest in carrying out extensive exploration activities in the same basin. Jurassic rocks especially Datta Sandstone and Samana Suk Limestone are acting as good reservoirs. The study unit consists of variegated sandstone interbedded with siltstone, carbonaceous clay, and shale and coal stringer. For the current work, two stratigraphic sections (Pezu and Abbo Wanda) have been measured. To examine its sedimentology, depositional environment, diagenetic settings, and reservoir characteristics, a detailed study was conducted and various laboratory techniques have been utilized. About 95 rock samples from the bottom to the top of both sections were collected, and 50 rock samples have been selected for thin section analysis and were examined under a polarizing microscope to show their mineralogical composition, diagenesis, and their reservoir characteristics. XRD (X-ray diffraction), Cathodoluminescence (CL), SEM (Scanning electron microscope) with EDS (Energy-dispersive spectroscope), and Core plug porosity and permeability analysis have been used to interpret its chemical and mineralogical composition and its reservoir characteristics, respectively. Based on field observations and thin section analysis, four depositional facies and six lithofacies have been established. The sedimentary structures, depositional facies, and lithofacies indicate that Datta Formation was deposited in a deltaic environment. Compactions, cementation, fracturing and dissolution can greatly affect the quality of reservoir rock. Based on thin section and SEM analysis, large numbers of primary pores, fracture and secondary pores were observed and connectivity between the pores is good, and at some places, these pores were filled through the authigenic clay minerals like kaolinite, mixed layers illite/smectite and chlorite that influences the reservoir characteristics. Primary pores (thin section) and secondary pores (dissolution pores) and core plug porosity and permeability data (porosity 13.23%-26.89% and permeability 0.12 to 149 mD) shows that Datta Formation has a good reservoir quality.
文摘This is a case report of a patient who presented to the Aga Khan University Hospital with generalized abdominal lymphadenopathy and high-grade fever.Due to ambiguous clinical findings,which were suggestive of either abdominal tuberculosis,or a lymphoma,the patient was started on empirical anti-tuberculous treatment due to the endemicity of tuberculosis in this region.The blood culture reports,however,were reported to grow colonies of Salmonella paratyphi A;thus the diagnosis of the patient was changed to enteric fever,and the patient improved on the subsequently started therapy of ceftriaxone 2000 mg bid.To the best of our knowledge,this is the first reported case of a patient suffering from enteric fever whose primary clinical findings were abdominal lymphadenopathy and fever.
文摘Persistent organic pollutants(POPs)persisting in the environment,which accumulate in human and animal tissue and bio-magnify in food-chains,would have significant impacts on human health and the environment.Thus,the present study was designed to investigate the accumulation of organic pollutants in prawn from streams of Sialkot,Pakistan.Fresh water prawn Macrobrachium lamarrei was captured from streams of study area.Samples were prepared for extraction of selected organic pollutants and then analyzed through gas chromatograph-electron capture detector(GC-ECD).Results of current study showed that five pesticide residues,i.e.,B-HCH,Lindane,DDD,2,4-DDT and 4,4-DDT were detected in composite prawn sample.The rest of POPs residues were not found in prawn.The ratio of a-HCH/γ-HCH indicated an input of technical HCH and long range transport,while the ratio of DDT/(DDD+DDE)showed recent use of DDT to the study area.The high values of TEC-HQ and PEC-HQ of POPs in the studied prawn samples depicted risk posed to health.
基金supported by the Science and Technology Project of the State Grid Corporation of China under Grant Number 5400202199541A-0-5-ZN。
文摘Power Line Communications-Artificial Intelligence of Things(PLC-AIo T)combines the low cost and high coverage of PLC with the learning ability of Artificial Intelligence(AI)to provide data collection and transmission capabilities for PLC-AIo T devices in smart parks.With the development of smart parks,their emerging services require secure and accurate time synchronization of PLC-AIo T devices.However,the impact of attackers on the accuracy of time synchronization cannot be ignored.To solve the aforementioned problems,we propose a tampering attack-aware Deep Q-Network(DQN)-based time synchronization algorithm.First,we construct an abnormal clock source detection model.Then,the abnormal clock source is detected and excluded by comparing the time synchronization information between the device and the gateway.Finally,the proposed algorithm realizes the joint guarantee of high accuracy and low delay for PLC-AIo T in smart parks by intelligently selecting the multi-clock source cooperation strategy and timing weights.Simulation results show that the proposed algorithm has better time synchronization delay and accuracy performance.
文摘Plant quality can directly and indirectly affect the third trophic level. The predation by all the instars of green lacewing, Chrysoperla carnea （S.） （Neuroptera： Chrysopidae） on the cereal aphids, Rhopalosiphum padi （L.）, and Sitobion avenae （F.） at varying nitrogen fertilizer levels was calculated under laboratory conditions. Wheat plants were grown on four nitrogen fertilizer levels and aphids were fed on these plants and subsequently offered as food to the C. carnea. Aphid densities of 10, 30, and 90 were offered to first, second, and third instar larvae of green lacewing. Increased nitrogen application improved nitrogen contents of the plants and also the body weight of cereal aphids feeding on them. Aphid consumption by green lacewings was reduced with the increase in nitrogen content in the host plants of aphids. Predation of both aphid species by first, second, and third instars larvae of C. carnea was highest on aphids reared on plants with the lowest rate of fertilization, suggesting a compensatory consumption to overcome reduced biomass （lower aphid size）. Total biomass devoured by C. carnea on all nitrogen fertilizer treatments was not statistically different. Additionally, the heavier host prey influenced by the plant nutrition had an effect on the life history characteristics of green lacewings. The larval duration, pupal weight, pupal duration, fecundity, and male and female longevity were significantly affected by the level of nitrogen fertilization to the aphid＇s host plants, except for pupal duration when fed on S. avenae. This study showed that quantity of prey supplied to the larvae affects the prey consumption and thereafter the life history characteristics of green lacewings.
基金supported by Government of Punjab, PakistanHigher Education Commission of Pakistan
文摘Pre-harvest sprouting in wheat is the germination of seeds within the spikes when rains occur after or during grain ripening, which occurs commonly in the barani tract of Pakistan. Therefore, 10 cultivars and five advanced lines of spring bread wheat were evaluated for pre-harvest sprouting resistance. After natural rainfall,seeds were immediately collected from the wet spikes and tested for germinating ability. Three different germination tests were applied to hand-threshed seed:(1) spikes threshed on the day of sampling and germination tested immediately,(2) spikes threshed on the day of sampling and germination tested 1 week later, and(3) spikes threshed 1 week after sampling and germination test immediately after threshing. Seeds and spikes kept for 1 week were place on blotting paper at room temperature.Cultivars BARS-09, 09 FJ17, Doukkala-12, NARC-09 and Ouassou-20 exhibited higher sprouting resistance while other genotypes were susceptible to pre-harvest sprouting in each of the three tests. A diallel crossing was conducted with six susceptible and two resistant genotypes to assess the genetic behavior of pre-harvest sprouting resistance.The combining ability(CA) demonstrated a higher proportion of additive genetic effects for sprouting resistance, because of higher variance of general and specific CA for both parameters under study. Doukkala-12 and BARS-09 showed increased pre-harvest sprouting resistance in their F1 descendants.
文摘Availability of mobile laboratories can facilitate rapid on-spot detection of pathogens,monitor its presence in certain populations and inform health authorities to take immediate remedial measures.Currently available biosafety and biosecurity guidelines and policies may not completely articulate the increased demand to manage mobile units in infectious disease outbreaks in remote parts of the country for rapid diagnosis,and also allows research and epidemiological study take place appropriately.The main objective of this study is to evaluate the current limitations and develop and implement biosafety and biosecurity guidelines as well as the protocols for operations,security,and response plan of mobile biosafety level 2 laboratories and their deployment.Keeping in view the sensitivity of it,a comprehensive plan was developed to address it in view of Global Health Security framework.Biosafety and biosecurity protocols were developed including Risk Assessment Tool(RAT)fitting the needs and strengthen the diagnostic and epidemiological capacity in the field covering remote parts of country to fill the gaps observed during the COVID-19 pandemic.Currently the biosafety and biosecurity best practices guidelines and biosecurity policy and regulations are directed mostly towards static laboratories.A biosafety and biosecurity manual developed to adopt and meet the requirements for MBSL 2.For acute health infectious threats including the COVID-19 outbreak and other epidemics,rapid diagnosis can curb and mitigate the problem before it gets out of its boundaries creating significant health risks for the public and economy.The deployment of mobile laboratories will certainly help in curbing these catastrophes.
基金supported by a Higher Education Commission(HEC),Pakistan’s Technology Development Fund Grant no.040 to the corresponding author.
文摘The response surface technique was applied to produce synbiotic yogurt containing Lacticaseibacillus rhamnosusand aloe vera gel (AVG) with high functionality (antioxidant and antimicrobial characters), superior physicochemicalproperties, and desirable sensory attributes. The experiments were planned around a central composite design (CCD)with two independent variables: AVG concentration (0–5%, w/w) and storage time (1–28 days). The AVG concentrationand storage time significantly improved the viability of L. rhamnosus up to 7.9 cfu/g during the shelf life which isa practical limit for a probiotic. It enhanced the yogurt’s antioxidant and antipathogenic activity, proteolytic content,water-holding capacity, and sensory aspects. High concentrations of AVG reduced the yogurt’s desirable texturalaspects (hardness and gumminess) except for firmness and adhesiveness and to some degree the sensory propertiesas well. The results showed that adding 5% AVG to probiotic yogurt produced a functional food with 68% desirabilitythat retained its beneficial properties for at least 14 days under refrigerated storage.
