AIM To evaluate the National Cancer Institute(NCI)Colorectal Cancer(CRC)Risk Assessment Tool as a predictor for the presence of adenomatous polyps(AP) found during screening or surveillance colonoscopy.METHODS This is...AIM To evaluate the National Cancer Institute(NCI)Colorectal Cancer(CRC)Risk Assessment Tool as a predictor for the presence of adenomatous polyps(AP) found during screening or surveillance colonoscopy.METHODS This is a retrospective single center observational study.We collected data of adenomatous polyps in each colonoscopy and then evaluated the lifetime CRC risk.We calculated the AP prevalence across risk score quintiles,odds ratios of the prevalence of AP across risk score quintiles,area under curves(AUCs)and Youden’s indexes to assess the optimal risk score cut off value for AP prevalence status.RESULTS The prevalence of AP gradually increased throughout the five risk score quintiles:i.e.,27.63%in the first and 51.35%in the fifth quintile.The odd ratios of AP prevalence in the fifth quintile compared to the first and second quintile were 2.76[confidence interval(CI):1.71-4.47]and 2.09(CI:1.32-3.30).The AUC for all patients was 0.62(CI:0.58-0.66).Youden’s Index indicated the optimal risk score cutoff value discriminating AP prevalence status was 3.60.CONCLUSION Patients with the higher NCI risk score have higher risk of AP and subsequent CRC;therefore,measures to increase the effectiveness of CRC detection in these patients include longer withdrawal time,early surveillance colonoscopy,and choosing flexible colonoscopy over other CRC screening modalities.展开更多
The soil steam injection method is one of the most effective disinfection methods,and the determination of the steam pipe structure parameters is very important.The steam capillary diameter(SCD)affects the steam flow ...The soil steam injection method is one of the most effective disinfection methods,and the determination of the steam pipe structure parameters is very important.The steam capillary diameter(SCD)affects the steam flow field in each pipe,which in turn affects the steam changes in the soil flow range and soil temperature(ST).Larger SCD would make lower ST in clay loam,silt loam,and sandy clay loam.The effectiveness of an SCD of 10 mm was verified by a mobile disinfection test at walking speeds of 10 cm/min and 30 cm/min under soil water content(SWC)of 15%and 35%,respectively.The results showed that when the walking speed was 10 cm/min,the initial SWC was proportional to the ST.However,when the walking speed was 30 cm/min,the law was exactly the opposite;that is,the initial water content is inversely proportional to the ST.The research can provide a theoretical research foundation for increasing soil temperature for efficient soil steam disinfection.展开更多
文摘AIM To evaluate the National Cancer Institute(NCI)Colorectal Cancer(CRC)Risk Assessment Tool as a predictor for the presence of adenomatous polyps(AP) found during screening or surveillance colonoscopy.METHODS This is a retrospective single center observational study.We collected data of adenomatous polyps in each colonoscopy and then evaluated the lifetime CRC risk.We calculated the AP prevalence across risk score quintiles,odds ratios of the prevalence of AP across risk score quintiles,area under curves(AUCs)and Youden’s indexes to assess the optimal risk score cut off value for AP prevalence status.RESULTS The prevalence of AP gradually increased throughout the five risk score quintiles:i.e.,27.63%in the first and 51.35%in the fifth quintile.The odd ratios of AP prevalence in the fifth quintile compared to the first and second quintile were 2.76[confidence interval(CI):1.71-4.47]and 2.09(CI:1.32-3.30).The AUC for all patients was 0.62(CI:0.58-0.66).Youden’s Index indicated the optimal risk score cutoff value discriminating AP prevalence status was 3.60.CONCLUSION Patients with the higher NCI risk score have higher risk of AP and subsequent CRC;therefore,measures to increase the effectiveness of CRC detection in these patients include longer withdrawal time,early surveillance colonoscopy,and choosing flexible colonoscopy over other CRC screening modalities.
基金The authors acknowledge that this work was financially supported by Jiangsu Province Science and Technology Support Plan Funded Project(Grant No.CX(16)1002)the Graduate Student Scientific Research Innovation Projects in Jiangsu Province(Grant No.KYCX17_0648).
文摘The soil steam injection method is one of the most effective disinfection methods,and the determination of the steam pipe structure parameters is very important.The steam capillary diameter(SCD)affects the steam flow field in each pipe,which in turn affects the steam changes in the soil flow range and soil temperature(ST).Larger SCD would make lower ST in clay loam,silt loam,and sandy clay loam.The effectiveness of an SCD of 10 mm was verified by a mobile disinfection test at walking speeds of 10 cm/min and 30 cm/min under soil water content(SWC)of 15%and 35%,respectively.The results showed that when the walking speed was 10 cm/min,the initial SWC was proportional to the ST.However,when the walking speed was 30 cm/min,the law was exactly the opposite;that is,the initial water content is inversely proportional to the ST.The research can provide a theoretical research foundation for increasing soil temperature for efficient soil steam disinfection.
