The Pissy granite quarry of Ouagadougou in Burkina Faso exists since 2006, and it is a source of financial incomes for many poor families working there. The Problem-In-Context framework (PiC), lead the current study t...The Pissy granite quarry of Ouagadougou in Burkina Faso exists since 2006, and it is a source of financial incomes for many poor families working there. The Problem-In-Context framework (PiC), lead the current study to understand better the quarry exploitation and structuration. Different motivations guide the quarry actors. Through those motivations, different solutions were suggested, mainly the shutdown of the quarry as the best way to decrease the impacts of the quarry exploitation on the environment, particularly regarding the air pollution and the loss of biodiversity in the area. The Pissy granite quarry is not recognized by the country’s legislation and this study is presenting the site organization. They are three main actors on the site and the tertiary actors are the ones having more incomes comparing to the primary and secondary actors of the chain. There is a need to evaluate the shell life of the quarry if the shutdown is not the final option chosen by the country. This evaluation should be a way to restructure the field and to have more incomes from it. Many standards exist in the country to guide the quarries and mines exploitation but they do not have impact on the Pissy granite quarry because of its non-reorganization.展开更多
Objective: To assess the antioxidant and anti-inflammatory activities as well as to determine the flavonoids and phenolic acids content of active fractions.Methods: Two medicinal plant samples were extracted successiv...Objective: To assess the antioxidant and anti-inflammatory activities as well as to determine the flavonoids and phenolic acids content of active fractions.Methods: Two medicinal plant samples were extracted successively in Soxhlet apparatus with n-hexane, dichloromethane, acetonitrile, ethyl acetate, methanol and n-butanol. Five methods were used to evaluate the antioxidant activity. Anti-inflammatory activity was done through the inhibition of the cyclooxygenase enzymes(COX-1 and COX-2).Polyphenolic compounds were analyzed by using a spectrophotometrical and high performance liquid chromatography-mass spectrometry(HPLC-MS) methods.Results: The data showed that the stem leaves extracts of Commiphora africana and Loeseneriella africana possessed significant in vitro antioxidant and anti-inflammatory activities. Polar extracts had radical scavenging effects and they reduced iron(III). The prostaglandin production was significantly stopped by acetonitrile and methanol extracts.These biological activities were supported by some bioactive compounds quantified by using the HPLC-MS. p-Coumaric acid, ferulic acid, isoquercitrin, quercitrin, quercetin,rutin, kaempferol and apigenin were the most metabolites quantified.Conclusions: The present study may explain the effectiveness of plants in traditional medicine of Burkina Faso, singularly Commiphora africana and Loeseneriella africana.The next investigation was to sub-fractionate the methanol fraction in order to isolate new antioxidant and/or anti-inflammatory compounds.展开更多
文摘The Pissy granite quarry of Ouagadougou in Burkina Faso exists since 2006, and it is a source of financial incomes for many poor families working there. The Problem-In-Context framework (PiC), lead the current study to understand better the quarry exploitation and structuration. Different motivations guide the quarry actors. Through those motivations, different solutions were suggested, mainly the shutdown of the quarry as the best way to decrease the impacts of the quarry exploitation on the environment, particularly regarding the air pollution and the loss of biodiversity in the area. The Pissy granite quarry is not recognized by the country’s legislation and this study is presenting the site organization. They are three main actors on the site and the tertiary actors are the ones having more incomes comparing to the primary and secondary actors of the chain. There is a need to evaluate the shell life of the quarry if the shutdown is not the final option chosen by the country. This evaluation should be a way to restructure the field and to have more incomes from it. Many standards exist in the country to guide the quarries and mines exploitation but they do not have impact on the Pissy granite quarry because of its non-reorganization.
基金Supported by International Foundation for Sciences(Grant No.AF/20286)
文摘Objective: To assess the antioxidant and anti-inflammatory activities as well as to determine the flavonoids and phenolic acids content of active fractions.Methods: Two medicinal plant samples were extracted successively in Soxhlet apparatus with n-hexane, dichloromethane, acetonitrile, ethyl acetate, methanol and n-butanol. Five methods were used to evaluate the antioxidant activity. Anti-inflammatory activity was done through the inhibition of the cyclooxygenase enzymes(COX-1 and COX-2).Polyphenolic compounds were analyzed by using a spectrophotometrical and high performance liquid chromatography-mass spectrometry(HPLC-MS) methods.Results: The data showed that the stem leaves extracts of Commiphora africana and Loeseneriella africana possessed significant in vitro antioxidant and anti-inflammatory activities. Polar extracts had radical scavenging effects and they reduced iron(III). The prostaglandin production was significantly stopped by acetonitrile and methanol extracts.These biological activities were supported by some bioactive compounds quantified by using the HPLC-MS. p-Coumaric acid, ferulic acid, isoquercitrin, quercitrin, quercetin,rutin, kaempferol and apigenin were the most metabolites quantified.Conclusions: The present study may explain the effectiveness of plants in traditional medicine of Burkina Faso, singularly Commiphora africana and Loeseneriella africana.The next investigation was to sub-fractionate the methanol fraction in order to isolate new antioxidant and/or anti-inflammatory compounds.
