Drosophila melanogaster has been a popular model organism in the study of sleep and circadian rhythm.The Drosophila activity monitoring(DAM)system is one of the many tools developed for investigating sleep behavior in...Drosophila melanogaster has been a popular model organism in the study of sleep and circadian rhythm.The Drosophila activity monitoring(DAM)system is one of the many tools developed for investigating sleep behavior in fruit flies and has been acknowledged by researchers around the world for its simplicity and cost-effectiveness.Based on the simple activity data collected by the DAM system,a wide range of parameters can be generated for sleep and circadian studies.However,current programs that analyze DAM data cover a limited number of metrics and fail to provide individual data for the user to plot graphs and conduct analysis using other software.Therefore,we have developed SleepyFlyR,an R package that:(1)is simple and easy to use with a user-friendly user interface script;(2)provides a comprehensive analysis of sleep and activity parameters;(3)generates double-plotted graphs for sleep and activity patterns;(4)offers visualization of sleep and activity profiles across multiple days or within a single day;(5)calculates the changes of sleep and activity parameters between baseline and experiment;(6)stores both summary data and individual data in files with unique title.展开更多
The influence of Al3Zr particles on the hot compression behavior and processing map(PM)of Al-Cu-Li based alloys under isothermal plane-strain compression in the temperature range of 400-500℃and at the strain rates of...The influence of Al3Zr particles on the hot compression behavior and processing map(PM)of Al-Cu-Li based alloys under isothermal plane-strain compression in the temperature range of 400-500℃and at the strain rates of 0.01-10 s^-1 was investigated.The corresponding microstructure was analyzed using optical microscopy(OM),electron back-scattered diffraction(EBSD)and transmission electron microscope(TEM).The results showed that dynamic recovery(DRV)played a greater role than dynamic recrystallization(DRX)in dynamic softening.At low temperatures,the Al3Zr particles were the significant barriers to inhibit DRV and DRX grain growth.When the temperature reached 500℃,the Al3Zr particles readily spread along grain boundaries just like a necklace due to the dissolution of Al3Zr particles and rapid diffusion of Zr through grain boundary,resulting in generating the macroscopic cracks and forming an instability domain at 490-500℃,0.01 s^-1 in the PM.展开更多
基金the National Natural Science Foundation of China(No.81970999)the Shanghai Rising Star Project(No.19QA1404900)。
文摘Drosophila melanogaster has been a popular model organism in the study of sleep and circadian rhythm.The Drosophila activity monitoring(DAM)system is one of the many tools developed for investigating sleep behavior in fruit flies and has been acknowledged by researchers around the world for its simplicity and cost-effectiveness.Based on the simple activity data collected by the DAM system,a wide range of parameters can be generated for sleep and circadian studies.However,current programs that analyze DAM data cover a limited number of metrics and fail to provide individual data for the user to plot graphs and conduct analysis using other software.Therefore,we have developed SleepyFlyR,an R package that:(1)is simple and easy to use with a user-friendly user interface script;(2)provides a comprehensive analysis of sleep and activity parameters;(3)generates double-plotted graphs for sleep and activity patterns;(4)offers visualization of sleep and activity profiles across multiple days or within a single day;(5)calculates the changes of sleep and activity parameters between baseline and experiment;(6)stores both summary data and individual data in files with unique title.
基金Project(11727802)supported by the National Natural Science Foundation of ChinaProjects(2018CDJSK04XK09,106112017CDJQJ328840)supported by the Fundamental Research Funds for the Central Universities,China。
文摘The influence of Al3Zr particles on the hot compression behavior and processing map(PM)of Al-Cu-Li based alloys under isothermal plane-strain compression in the temperature range of 400-500℃and at the strain rates of 0.01-10 s^-1 was investigated.The corresponding microstructure was analyzed using optical microscopy(OM),electron back-scattered diffraction(EBSD)and transmission electron microscope(TEM).The results showed that dynamic recovery(DRV)played a greater role than dynamic recrystallization(DRX)in dynamic softening.At low temperatures,the Al3Zr particles were the significant barriers to inhibit DRV and DRX grain growth.When the temperature reached 500℃,the Al3Zr particles readily spread along grain boundaries just like a necklace due to the dissolution of Al3Zr particles and rapid diffusion of Zr through grain boundary,resulting in generating the macroscopic cracks and forming an instability domain at 490-500℃,0.01 s^-1 in the PM.
