Objective: To compare the long term efficacy of transobturator Tape (TOT) with tension free vaginal tape (TVT) at 24 months postoperatively. Patients & Methods: 160 women with stress urinary incontinence (SUI) wer...Objective: To compare the long term efficacy of transobturator Tape (TOT) with tension free vaginal tape (TVT) at 24 months postoperatively. Patients & Methods: 160 women with stress urinary incontinence (SUI) were randomly allocated to either TVT or TOT procedures and reviewed at 24 months after surgery. The primary outcomes were objective cure (a negative cough stress test, and a negative 1-hour pad test), and subjective cure (defined as “very much better” or “much better” improvement in the Patient Global Impression of Improvement scale). The secondary outcomes included incontinence related quality of life (using Urogenital Distress Inventory Questionnaire, and Incontinence Impact Questionnaire), and complications. Results: No statistical difference was reported in objective and subjective cure rates between both groups. Objective cure rate was 85.6% and 81.6% in the TOT and TVT groups respectively (P = 0.55). Subjective cure rate in the TOT and TVT groups were 87% and 83% respectively (P = 0.68). There were no significant differences in postoperative complications and incontinence related quality of life. However, the operating time was significantly shorter in the TOT group compared with the TVT group (22.6 ± 3.9, 27.1 ± 3;respectively, P < 0.001). Conclusion: TOT and TVT procedures were equally efficient and safe for treatment of SUI, with maintenance of high objective and subjective cure rates for 24 months. Longer follow-up is needed to confirm these results.展开更多
Purpose The present work deals with the natural radioactivity levels of basement rocks from Gabel Abu El-Hassan in the North Eastern Desert of Egypt.Methods The activity concentrations of 226Ra,232Th and 40K in rock s...Purpose The present work deals with the natural radioactivity levels of basement rocks from Gabel Abu El-Hassan in the North Eastern Desert of Egypt.Methods The activity concentrations of 226Ra,232Th and 40K in rock samples were measured using a gamma-ray spectrometry with an HPGe detector.Landsat Enhanced Thematic Mapper Plus(ETM+)data were processed and interpreted to create rock forming radioactive map.Results and conclusion The activity concentrations of 226Ra,232Th and 40K varied from 28.2±9.4 to 259.6±38.6 Bq/kg,37.9±9.9 to 297.4±54.6 Bq/kg and 487.0±73.4 to 5514.6±786.0 Bq/kg,respectively.The radiological hazard indices(gamma index),the annual effective dose rate and excess life-time cancer risk were estimated to assess the radiological hazards due to the use of rock samples as building material.Remote sensing data were also used to integrate between radioactive analysis and Landsat-7(ETM+)data processing to detect radioactive anomalies and to identify the uraniferous alteration zones in Abu El-Hassan area.展开更多
Background The lifetime occurrence of urinary stones is approximately 1%–15%,and the peak age of occurrence is 30 years.Approximately one fifths of urinary tract stones are found in the ureter,of which two thirds are...Background The lifetime occurrence of urinary stones is approximately 1%–15%,and the peak age of occurrence is 30 years.Approximately one fifths of urinary tract stones are found in the ureter,of which two thirds are in the distal ureter.Many drugs,including phosphodiesterase-5 inhibitors(PDE5Is)andα-blockers,are used to relax the smooth muscles in medical expulsive therapy(MET).We aimed to compare the combination of tadalafil and tamsulosin versus tadalafil alone as MET for stones in the L1/3 ureter of 10 mm or less.Materials and methods A total of 150 patients with L1/3 ureteric stones measuring 10 mm or less were enrolled in the study and randomly assigned to one of 3 equal groups using a computer-generated random number.Patients in group A prescribed tadalafil 10 mg/d.However,those in group B were prescribed tamsulosin 0.4 mg and tadalafil 10 mg/d,whereas those in group C received a placebo once daily.Stone expulsion rate and pain recurrence were evaluated after 14 days.Results The stone expulsion rate was significantly higher in the tadalafil and tamsulosin groups and the tamsulosin group than in the placebo group in the current study by 68%in the combination group,64%in the tadalafil alone group,and 42%in the placebo group(p=0.019).In the current study,a combination was associated with lower pain recurrence than tadalafil alone or placebo,with means of 1.06,1.9,2.98(with a p value of 0.001).Stone size was not effective in any group.Conclusions The combination of PDE5Is andα-blockers effectively increases the expulsion of lower ureteric stones(5–10 mm),but with the same effect as PDE5Is alone,with the advantage of decreasing pain recurrence.Stone size did not affect the expulsion rate in patients who received MET for stones less than 1 cm in size.展开更多
文摘Objective: To compare the long term efficacy of transobturator Tape (TOT) with tension free vaginal tape (TVT) at 24 months postoperatively. Patients & Methods: 160 women with stress urinary incontinence (SUI) were randomly allocated to either TVT or TOT procedures and reviewed at 24 months after surgery. The primary outcomes were objective cure (a negative cough stress test, and a negative 1-hour pad test), and subjective cure (defined as “very much better” or “much better” improvement in the Patient Global Impression of Improvement scale). The secondary outcomes included incontinence related quality of life (using Urogenital Distress Inventory Questionnaire, and Incontinence Impact Questionnaire), and complications. Results: No statistical difference was reported in objective and subjective cure rates between both groups. Objective cure rate was 85.6% and 81.6% in the TOT and TVT groups respectively (P = 0.55). Subjective cure rate in the TOT and TVT groups were 87% and 83% respectively (P = 0.68). There were no significant differences in postoperative complications and incontinence related quality of life. However, the operating time was significantly shorter in the TOT group compared with the TVT group (22.6 ± 3.9, 27.1 ± 3;respectively, P < 0.001). Conclusion: TOT and TVT procedures were equally efficient and safe for treatment of SUI, with maintenance of high objective and subjective cure rates for 24 months. Longer follow-up is needed to confirm these results.
文摘Purpose The present work deals with the natural radioactivity levels of basement rocks from Gabel Abu El-Hassan in the North Eastern Desert of Egypt.Methods The activity concentrations of 226Ra,232Th and 40K in rock samples were measured using a gamma-ray spectrometry with an HPGe detector.Landsat Enhanced Thematic Mapper Plus(ETM+)data were processed and interpreted to create rock forming radioactive map.Results and conclusion The activity concentrations of 226Ra,232Th and 40K varied from 28.2±9.4 to 259.6±38.6 Bq/kg,37.9±9.9 to 297.4±54.6 Bq/kg and 487.0±73.4 to 5514.6±786.0 Bq/kg,respectively.The radiological hazard indices(gamma index),the annual effective dose rate and excess life-time cancer risk were estimated to assess the radiological hazards due to the use of rock samples as building material.Remote sensing data were also used to integrate between radioactive analysis and Landsat-7(ETM+)data processing to detect radioactive anomalies and to identify the uraniferous alteration zones in Abu El-Hassan area.
文摘Background The lifetime occurrence of urinary stones is approximately 1%–15%,and the peak age of occurrence is 30 years.Approximately one fifths of urinary tract stones are found in the ureter,of which two thirds are in the distal ureter.Many drugs,including phosphodiesterase-5 inhibitors(PDE5Is)andα-blockers,are used to relax the smooth muscles in medical expulsive therapy(MET).We aimed to compare the combination of tadalafil and tamsulosin versus tadalafil alone as MET for stones in the L1/3 ureter of 10 mm or less.Materials and methods A total of 150 patients with L1/3 ureteric stones measuring 10 mm or less were enrolled in the study and randomly assigned to one of 3 equal groups using a computer-generated random number.Patients in group A prescribed tadalafil 10 mg/d.However,those in group B were prescribed tamsulosin 0.4 mg and tadalafil 10 mg/d,whereas those in group C received a placebo once daily.Stone expulsion rate and pain recurrence were evaluated after 14 days.Results The stone expulsion rate was significantly higher in the tadalafil and tamsulosin groups and the tamsulosin group than in the placebo group in the current study by 68%in the combination group,64%in the tadalafil alone group,and 42%in the placebo group(p=0.019).In the current study,a combination was associated with lower pain recurrence than tadalafil alone or placebo,with means of 1.06,1.9,2.98(with a p value of 0.001).Stone size was not effective in any group.Conclusions The combination of PDE5Is andα-blockers effectively increases the expulsion of lower ureteric stones(5–10 mm),but with the same effect as PDE5Is alone,with the advantage of decreasing pain recurrence.Stone size did not affect the expulsion rate in patients who received MET for stones less than 1 cm in size.
