Background: Mosquito bite reaction is a common skin disease. Topical steroids and oral antihistamines are the conventional treatment. However, the side effects from prolonged use of topical steroids are the limitation...Background: Mosquito bite reaction is a common skin disease. Topical steroids and oral antihistamines are the conventional treatment. However, the side effects from prolonged use of topical steroids are the limitation of the treatment. Recently, herbal extracts are emerging interest for an alternative anti-inflammatory dermatoses therapy. Objective: To assess the effectiveness of herbal extracted gel containing, Perilla frutescens, Portulaca oleracea, Ipomoea pescaprae, Aloe vera, Centella asiatica and Broussonetia papyrifera in comparing with 1% hydrocortisone (HC) gel. Material and Methods: An experimental study was conducted on 50 mosquito bite hypersensitive volunteers (15 - 19 years old) with double-blinded split randomized control method. After the volunteers were exposed for one bite on their arms by a non-infectious mosquito, Aedes albopictus, the drugs were applied twice daily. The diameter of lesion, pruritus analog score, erythema and melanin index were measured at 2, 6, 24 hours and 2, 3, 4 weeks. The volunteers “self-satisfaction” and side effects were recorded. Results: The mean age was 17.42 ± 1.14 years old. The diameter of lesion, pruritus analog score, erythema and melanin index were decreased on both sides at each visit with significant difference (p < 0.05). There was no significant difference between two agents of all parameters and the satisfaction of the volunteers (p > 0.05). The post-inflammatory hyperpigmentation rate of 1% HC and herbal gel was 64% and 54% respectively without significant difference (p = 0.267). Conclusion: The herbal gel was as effective as 1% HC for the treatment of acute and late reaction of mosquito bite reaction in adolescent. It may be used as the alternative treatment for mosquito bite reaction.展开更多
Atopic dermatitis is a chronic, relapsing and extremely pruritic eczematous disease which commonly affects children. The standard management consists of a combination of anti-inflammatory drugs in adjunctive with skin...Atopic dermatitis is a chronic, relapsing and extremely pruritic eczematous disease which commonly affects children. The standard management consists of a combination of anti-inflammatory drugs in adjunctive with skin care management particular moisturizer application. A concern for the side effects associated with long term use of corticosteroids has also been considered. There has been an emerging interest in moisturizer containing non-steroidal anti-inflammatory agents such as herbal extracts, vitamins, mineral and lipids. The in vitro and the in vivo studies of each agent were reviewed. The clinical study on the efficacy of moisturizers containing these agents were also demonstrated including the author's studies and clinicalexperience. These moisturizers might be considered as an alternative treatment in acute flare of mild to moderate atopic dermatitis.展开更多
Background: Ultraviolet radiation (UVR) causes harm to the eye and skin in human. There are many ways to protect one from UVR. Umbrella is widely used due to its convenience as well as its ability to protect one from ...Background: Ultraviolet radiation (UVR) causes harm to the eye and skin in human. There are many ways to protect one from UVR. Umbrella is widely used due to its convenience as well as its ability to protect one from rain. However, there are limited numbers of studies on UVR protection of different types of umbrellas. Objective of study: To determine UVR protection efficacy of different umbrella designs. Methods: The experimental study was performed on five sunny days. Six manikins were placed in an open area, five of which were equipped with five different types of black canopy umbrellas. One manikin was placed without an umbrella as a control sample. Polysulfone film badges were attached in six different areas in each manikin for measuring the UVR from 10 am - 3 pm Results: All types of umbrellas provides 64.5% - 92.3% UVR photo protection efficacy. An umbrella with UV-filter coating on the inner surface provides maximum UVR photo protection efficacy. However, UVR proto protection efficacies of an umbrella with UV-filter coating on the inner surface and one with UV-filter coating on the outer surface and one without UV-filter coating are not statistically significant (p-value = 0.37). Umbrellas with a diameter of 122 cm and 152 cm provide comparable UVR photo protection efficacy while an umbrella with a diameter of 112 cm provides the least UVR photo protection efficacy. However, UVR photo protection efficacies of umbrellas with different diameter are not statistically significant (p-value = 0.36). The area of the body that received the most UVR photo protection is the forehead which is statistically significant when compared with other areas of the body (p-value < 0.001). The areas of the body that received the least UVR photo protection are the left ear and the back of the neck, which are statistically significant when compared with other areas of the body (p-value < 0.001). Conclusion: All types of umbrellas provide UVR photo protection efficacy. The study shows that umbrellas with different canvas material including both the UV-filter coating and different diameter of umbrellas could effectively protect the user from UVR without significant group difference in this study.展开更多
文摘Background: Mosquito bite reaction is a common skin disease. Topical steroids and oral antihistamines are the conventional treatment. However, the side effects from prolonged use of topical steroids are the limitation of the treatment. Recently, herbal extracts are emerging interest for an alternative anti-inflammatory dermatoses therapy. Objective: To assess the effectiveness of herbal extracted gel containing, Perilla frutescens, Portulaca oleracea, Ipomoea pescaprae, Aloe vera, Centella asiatica and Broussonetia papyrifera in comparing with 1% hydrocortisone (HC) gel. Material and Methods: An experimental study was conducted on 50 mosquito bite hypersensitive volunteers (15 - 19 years old) with double-blinded split randomized control method. After the volunteers were exposed for one bite on their arms by a non-infectious mosquito, Aedes albopictus, the drugs were applied twice daily. The diameter of lesion, pruritus analog score, erythema and melanin index were measured at 2, 6, 24 hours and 2, 3, 4 weeks. The volunteers “self-satisfaction” and side effects were recorded. Results: The mean age was 17.42 ± 1.14 years old. The diameter of lesion, pruritus analog score, erythema and melanin index were decreased on both sides at each visit with significant difference (p < 0.05). There was no significant difference between two agents of all parameters and the satisfaction of the volunteers (p > 0.05). The post-inflammatory hyperpigmentation rate of 1% HC and herbal gel was 64% and 54% respectively without significant difference (p = 0.267). Conclusion: The herbal gel was as effective as 1% HC for the treatment of acute and late reaction of mosquito bite reaction in adolescent. It may be used as the alternative treatment for mosquito bite reaction.
文摘Atopic dermatitis is a chronic, relapsing and extremely pruritic eczematous disease which commonly affects children. The standard management consists of a combination of anti-inflammatory drugs in adjunctive with skin care management particular moisturizer application. A concern for the side effects associated with long term use of corticosteroids has also been considered. There has been an emerging interest in moisturizer containing non-steroidal anti-inflammatory agents such as herbal extracts, vitamins, mineral and lipids. The in vitro and the in vivo studies of each agent were reviewed. The clinical study on the efficacy of moisturizers containing these agents were also demonstrated including the author's studies and clinicalexperience. These moisturizers might be considered as an alternative treatment in acute flare of mild to moderate atopic dermatitis.
文摘Background: Ultraviolet radiation (UVR) causes harm to the eye and skin in human. There are many ways to protect one from UVR. Umbrella is widely used due to its convenience as well as its ability to protect one from rain. However, there are limited numbers of studies on UVR protection of different types of umbrellas. Objective of study: To determine UVR protection efficacy of different umbrella designs. Methods: The experimental study was performed on five sunny days. Six manikins were placed in an open area, five of which were equipped with five different types of black canopy umbrellas. One manikin was placed without an umbrella as a control sample. Polysulfone film badges were attached in six different areas in each manikin for measuring the UVR from 10 am - 3 pm Results: All types of umbrellas provides 64.5% - 92.3% UVR photo protection efficacy. An umbrella with UV-filter coating on the inner surface provides maximum UVR photo protection efficacy. However, UVR proto protection efficacies of an umbrella with UV-filter coating on the inner surface and one with UV-filter coating on the outer surface and one without UV-filter coating are not statistically significant (p-value = 0.37). Umbrellas with a diameter of 122 cm and 152 cm provide comparable UVR photo protection efficacy while an umbrella with a diameter of 112 cm provides the least UVR photo protection efficacy. However, UVR photo protection efficacies of umbrellas with different diameter are not statistically significant (p-value = 0.36). The area of the body that received the most UVR photo protection is the forehead which is statistically significant when compared with other areas of the body (p-value < 0.001). The areas of the body that received the least UVR photo protection are the left ear and the back of the neck, which are statistically significant when compared with other areas of the body (p-value < 0.001). Conclusion: All types of umbrellas provide UVR photo protection efficacy. The study shows that umbrellas with different canvas material including both the UV-filter coating and different diameter of umbrellas could effectively protect the user from UVR without significant group difference in this study.
