Purpose:Non-operative management(NOM)has been validated for blunt liver and splenic injuries.Literature on continuous intra-abdominal pressure(IAP)monitoring as a part of NOM remains to be equivocal.The study aimed to...Purpose:Non-operative management(NOM)has been validated for blunt liver and splenic injuries.Literature on continuous intra-abdominal pressure(IAP)monitoring as a part of NOM remains to be equivocal.The study aimed to find any correlation between clinical parameters and IAP,and their effect on the NOM of patients with blunt liver and splenic injury.Method:A prospective cross-sectional study conducted at a level I trauma center from October 2018 to January 2020 including 174 patients who underwent NOM following blunt liver and splenic injuries.Hemodynamically unstable patients or those on ventilators were excluded,as well as patients who suffered significant head,spinal cord,and/or bladder injuries.The study predominantly included males(83.9%)with a mean age of 32.5 years.IAP was monitored continuously and the relation of IAP with various parameters,interventions,and outcomes were measured.Data were summarized as frequency(percentage)or mean±SD or median(Q1,Q3)as indicated.χ2 or Fisher's exact test was used for categorical variables,while for continuous variables parametric(independent t-test)or nonparametric tests(Wilcoxon rank sum test)were used as appropriate.Clinical and laboratory correlates of IAP<12 with p<0.200 in the univariable logistic regression analysis were included in the multivariable analysis.A p<0.05 was used to indicate statistical significance.Results:Intra-abdominal hypertension(IAH)was seen in 19.0%of the study population.IAH was strongly associated with a high injury severity score(p<0.001),and other physiological parameters like respiratory rate(p<0.001),change in abdominal girth(AG)(p<0.001),and serum creatinine(p<0.001).IAH along with the number of solid organs involved,respiratory rate,change in AG,and serum creatinine was associated with the intervention,either operative or non-operative(p=0.001,p=0.002,p<0.001,p<0.001,p=0.013,respectively).On multivariable analysis,IAP(p=0.006)and the mean change of AG(p=0.004)were significantly associated with the need for intervention.Conclusion:As a part of NOM,IAP should be monitored as a continuous vital.However,the decision for any intervention,either operative or non-operative cannot be guided by IAP values alone.展开更多
文摘Purpose:Non-operative management(NOM)has been validated for blunt liver and splenic injuries.Literature on continuous intra-abdominal pressure(IAP)monitoring as a part of NOM remains to be equivocal.The study aimed to find any correlation between clinical parameters and IAP,and their effect on the NOM of patients with blunt liver and splenic injury.Method:A prospective cross-sectional study conducted at a level I trauma center from October 2018 to January 2020 including 174 patients who underwent NOM following blunt liver and splenic injuries.Hemodynamically unstable patients or those on ventilators were excluded,as well as patients who suffered significant head,spinal cord,and/or bladder injuries.The study predominantly included males(83.9%)with a mean age of 32.5 years.IAP was monitored continuously and the relation of IAP with various parameters,interventions,and outcomes were measured.Data were summarized as frequency(percentage)or mean±SD or median(Q1,Q3)as indicated.χ2 or Fisher's exact test was used for categorical variables,while for continuous variables parametric(independent t-test)or nonparametric tests(Wilcoxon rank sum test)were used as appropriate.Clinical and laboratory correlates of IAP<12 with p<0.200 in the univariable logistic regression analysis were included in the multivariable analysis.A p<0.05 was used to indicate statistical significance.Results:Intra-abdominal hypertension(IAH)was seen in 19.0%of the study population.IAH was strongly associated with a high injury severity score(p<0.001),and other physiological parameters like respiratory rate(p<0.001),change in abdominal girth(AG)(p<0.001),and serum creatinine(p<0.001).IAH along with the number of solid organs involved,respiratory rate,change in AG,and serum creatinine was associated with the intervention,either operative or non-operative(p=0.001,p=0.002,p<0.001,p<0.001,p=0.013,respectively).On multivariable analysis,IAP(p=0.006)and the mean change of AG(p=0.004)were significantly associated with the need for intervention.Conclusion:As a part of NOM,IAP should be monitored as a continuous vital.However,the decision for any intervention,either operative or non-operative cannot be guided by IAP values alone.
