The Global Health Network Conference 2022 addressed the critical need for expanded health research capabilities in low-and middle-income countries and low-resource settings,particularly in light of global health threa...The Global Health Network Conference 2022 addressed the critical need for expanded health research capabilities in low-and middle-income countries and low-resource settings,particularly in light of global health threats such as pandemics and climate change.This deficit often results in insufficient research to inform effective health interventions.Held in Cape Town,South Africa,the conference brought together a diverse group of health researchers,practitioners,and policymakers from over 50 countries to explore how health research can be embedded into every healthcare setting.The conference emphasized fostering leadership,integrating research findings into policy and practice,enabling research in all healthcare settings,and engaging communities through the research process.This article collates and considers the key findings and recommendations from the eight sessions.These sessions were designed to follow the research cycle,from setting the question to taking the findings into practice,with a focus on capacity building,data-driven decision-making,and tackling gender and societal disparities.Our aim is that by reporting these outputs we can share valuable experience and insights that can help research teams in their studies and through doing so,spark a shift in global health research through this remarkable collaborative effort in knowledge and methods sharing that continues through the Global Health Network community.The recommendations derived from this conference align with the World Health Organization's strategies for reinforcing health research systems and showcase the importance of empowering low-and middle-income countries to conduct research that addresses their unique health challenges.By advancing global health research through collaboration,innovation,and community involvement,the conference laid the groundwork for a comprehensive framework that supports the Sustainable Development Goals and promotes equitable healthcare for all.展开更多
Current interest in deep,low-permeability formations(<10 md)demands accelerated development of high-temperature hydraulic fracturing technologies.Conventional guar systems break down above 300°F and require hi...Current interest in deep,low-permeability formations(<10 md)demands accelerated development of high-temperature hydraulic fracturing technologies.Conventional guar systems break down above 300°F and require higher polymer loadings to maintain thermal stability.However,higher polymer loadings generate more residue and damage to the proppant pack and the formation.To resolve these problems,a variety of high-temperature stabilizers are added to enhance the thermal stability of these fracturing fluids at temperatures above 300F.The focus of this work is to:(1)identify those additives that best enhance temperature stability of fracturing fluids and(2)study the rheological influence of incorporating these additives on the fracturing fluid systems.The experimental fracturing-fluid solutions were prepared at a total polymer concentration of 30 and 40 lb/1000 gal.Additives such as synthetic polymer,oxygen scavengers,crosslinkers,crosslinker delay additives,and pH buffers were examined in this work.Hydrated polymer solutions were crosslinked with a metallic crosslinker between 200 and 400°F.Viscosity measurements were carried out in a highpressure/high-temperature(HP/HT)rheometer to evaluate rheology and thermal stability.Results show that adding a synthetic polymer and a crosslinker with the slowest reaction rate improves the fracturing fluid thermal stability.Of the three other additives tested,oxygen scavengers showed the greatest enhancement to thermal stability while pH buffers showed the least.Through the addition of high-temperature stabilizing additives,the fracturing fluid in this work was able to maintain a stable performance at temperatures up to 400°F.Maintaining the thermal stability of fracturing fluids at a lower polymer loading remains a challenge in the industry.This work proposes techniques that can be used to enhance the thermal stability of fracturing fluids.Deeper knowledge about these different techniques will allow for better additive development and application in the field.展开更多
文摘The Global Health Network Conference 2022 addressed the critical need for expanded health research capabilities in low-and middle-income countries and low-resource settings,particularly in light of global health threats such as pandemics and climate change.This deficit often results in insufficient research to inform effective health interventions.Held in Cape Town,South Africa,the conference brought together a diverse group of health researchers,practitioners,and policymakers from over 50 countries to explore how health research can be embedded into every healthcare setting.The conference emphasized fostering leadership,integrating research findings into policy and practice,enabling research in all healthcare settings,and engaging communities through the research process.This article collates and considers the key findings and recommendations from the eight sessions.These sessions were designed to follow the research cycle,from setting the question to taking the findings into practice,with a focus on capacity building,data-driven decision-making,and tackling gender and societal disparities.Our aim is that by reporting these outputs we can share valuable experience and insights that can help research teams in their studies and through doing so,spark a shift in global health research through this remarkable collaborative effort in knowledge and methods sharing that continues through the Global Health Network community.The recommendations derived from this conference align with the World Health Organization's strategies for reinforcing health research systems and showcase the importance of empowering low-and middle-income countries to conduct research that addresses their unique health challenges.By advancing global health research through collaboration,innovation,and community involvement,the conference laid the groundwork for a comprehensive framework that supports the Sustainable Development Goals and promotes equitable healthcare for all.
基金The authors thank Gia Alexander for editorial assistance in preparing this paper.
文摘Current interest in deep,low-permeability formations(<10 md)demands accelerated development of high-temperature hydraulic fracturing technologies.Conventional guar systems break down above 300°F and require higher polymer loadings to maintain thermal stability.However,higher polymer loadings generate more residue and damage to the proppant pack and the formation.To resolve these problems,a variety of high-temperature stabilizers are added to enhance the thermal stability of these fracturing fluids at temperatures above 300F.The focus of this work is to:(1)identify those additives that best enhance temperature stability of fracturing fluids and(2)study the rheological influence of incorporating these additives on the fracturing fluid systems.The experimental fracturing-fluid solutions were prepared at a total polymer concentration of 30 and 40 lb/1000 gal.Additives such as synthetic polymer,oxygen scavengers,crosslinkers,crosslinker delay additives,and pH buffers were examined in this work.Hydrated polymer solutions were crosslinked with a metallic crosslinker between 200 and 400°F.Viscosity measurements were carried out in a highpressure/high-temperature(HP/HT)rheometer to evaluate rheology and thermal stability.Results show that adding a synthetic polymer and a crosslinker with the slowest reaction rate improves the fracturing fluid thermal stability.Of the three other additives tested,oxygen scavengers showed the greatest enhancement to thermal stability while pH buffers showed the least.Through the addition of high-temperature stabilizing additives,the fracturing fluid in this work was able to maintain a stable performance at temperatures up to 400°F.Maintaining the thermal stability of fracturing fluids at a lower polymer loading remains a challenge in the industry.This work proposes techniques that can be used to enhance the thermal stability of fracturing fluids.Deeper knowledge about these different techniques will allow for better additive development and application in the field.
