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Mapping Metabolic Dysfunction-associated Steatotic Liver Disease Models of Care across 17 Middle East and North Africa Countries:Insights into Guidelines,Infrastructure,and Referral Systems 被引量:1
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作者 Mohamed El-Kassas Khalid MAlNaamani +19 位作者 Rofida Khalifa Yusuf Yilmaz Asma Labidi Maen Almattooq Faisal MSanai Maisam WIAkroush Nabil Debzi mohammed amedhat Imam Waked Ali Tumi Mohamed Elbadry mohammed Omer mohammed Ala ISharara Ali El Houni Mohamed Alsenbesy Hisham El-Khayat Mina Tharwat Abdel-Naser Elzouki Khalid AAlswat Zobair MYounossi 《Journal of Clinical and Translational Hepatology》 2025年第10期791-808,共18页
Background and Aims:Metabolic dysfunction-associated steatotic liver disease(MASLD)represents an escalating healthcare burden across the Middle East and North Africa(MENA)region;however,system-level preparedness remai... Background and Aims:Metabolic dysfunction-associated steatotic liver disease(MASLD)represents an escalating healthcare burden across the Middle East and North Africa(MENA)region;however,system-level preparedness remains largely undefined.This study aimed to assess existing models of care,clinical infrastructure,policy frameworks,and provider perspectives across 17 MENA countries.Methods:A cross-sectional,mixed-methods survey was distributed to clinicians from MASLD-related specialties across the region.A total of 130 experts(87.2%response rate)from academic,public,and private sectors in 17 countries participated.The questionnaire addressed national policies,diagnostic and therapeutic practices,referral pathways,multidisciplinary team(MDT)integration,and patient/public engagement.Quantitative responses were analyzed descriptively,while qualitative inputs underwent thematic analysis.Results:Only 35.4%of respondents confirmed the presence of national clinical guidelines for MASLD,and 73.1%reported the absence of a national strategy.Structured referral pathways were reported by 39.2%of participants,and only 31.5%believed the current model adequately addresses MASLD.While 60%supported MDT approaches,implementation remained inconsistent.Limited access to transient elastography was reported by 26.2%of providers.Public education efforts were minimal:22.3%reported no available tools,and 87.7%indicated the absence of patient-reported outcomes data.Nearly half(47.7%)cited poor patient adherence,attributed to low awareness,financial barriers,and lack of follow-up.Conclusions:Significant policy,structural,and educational gaps persist in MASLD care across the MENA region.To address this rising burden,countries must adopt integrated national strategies,expand access to non-invasive diagnostic tests,institutionalize MDT care,and invest in both public and provider education as essential pillars of system-wide preparedness. 展开更多
关键词 Metabolic dysfunction-associated steatotic liver disease MASLD Middle East and North Africa region MENA Models of care MoCs Multidisciplinary care.
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