Designed and synthesized a new highly water soluble N,N^1-bis（2-（（5-（（dimethylamino）methyl）furan-2-yl）methylthio）ethyl）-perylene -3,4,9,10-tetracarboxylic diimide from 2-（（5-（（dimethylamino）methyl）fura...Designed and synthesized a new highly water soluble N,N^1-bis（2-（（5-（（dimethylamino）methyl）furan-2-yl）methylthio）ethyl）-perylene -3,4,9,10-tetracarboxylic diimide from 2-（（5-（（dimethylamino）methyl）furan-2-yl）methylthio）ethanamine and perylene-3,4,9,10- tetracarboxylic dianhydride.The compound was characterized by ~1H,^（13）C,2D NMR,mass and IR techniques.The compound is highly fluorescent with good solubility in water and other polar solvents.展开更多
Some new pyridazinone derivatives(3) were synthesized through addition of antipyrin to β- aroylacrylic acids (1) followed by cyclization of the adducts. Reactions of 3 with ethyl bromoacetate, benzenesulfonyl chlorid...Some new pyridazinone derivatives(3) were synthesized through addition of antipyrin to β- aroylacrylic acids (1) followed by cyclization of the adducts. Reactions of 3 with ethyl bromoacetate, benzenesulfonyl chloride, benzoyl chloride and POCl_3 give N-substituted products and monochlorosub- stituted pyridazines (4), respectively. The reactions of the latter with thiourea give unexpected dithio- derivatives(5), which react with phenylhydrazine to give pyrazolopyridazino pyridazine derivatives (6). Reactions of 2 with NH_2OH in ethanol and pyridine afford oxime and oxazinone derivatives 7 and 8, tespectively. The antibacterial activities of several compounds were screened.展开更多
文摘Designed and synthesized a new highly water soluble N,N^1-bis（2-（（5-（（dimethylamino）methyl）furan-2-yl）methylthio）ethyl）-perylene -3,4,9,10-tetracarboxylic diimide from 2-（（5-（（dimethylamino）methyl）furan-2-yl）methylthio）ethanamine and perylene-3,4,9,10- tetracarboxylic dianhydride.The compound was characterized by ~1H,^（13）C,2D NMR,mass and IR techniques.The compound is highly fluorescent with good solubility in water and other polar solvents.
文摘Some new pyridazinone derivatives(3) were synthesized through addition of antipyrin to β- aroylacrylic acids (1) followed by cyclization of the adducts. Reactions of 3 with ethyl bromoacetate, benzenesulfonyl chloride, benzoyl chloride and POCl_3 give N-substituted products and monochlorosub- stituted pyridazines (4), respectively. The reactions of the latter with thiourea give unexpected dithio- derivatives(5), which react with phenylhydrazine to give pyrazolopyridazino pyridazine derivatives (6). Reactions of 2 with NH_2OH in ethanol and pyridine afford oxime and oxazinone derivatives 7 and 8, tespectively. The antibacterial activities of several compounds were screened.
