在当下集成电路(integrated circuit, IC)设计规模不断增大的背景下,芯片验证工作所占比重随之日益增加。该研究提出了一种基于C语言源程序实现复杂系统级芯片(system on chip, SOC)系统级验证的方法,其主要思想是以数字信号处理器(digi...在当下集成电路(integrated circuit, IC)设计规模不断增大的背景下,芯片验证工作所占比重随之日益增加。该研究提出了一种基于C语言源程序实现复杂系统级芯片(system on chip, SOC)系统级验证的方法,其主要思想是以数字信号处理器(digital signal processor, DSP)内核为运算核心,结合图像处理、点云生成算法等算法运算,通过增强型直接内存存取器(enhanced direct memory access, EDMA)进行数据搬移,最后将运算后的数据与通过MATLAB搭建的算法模型运算得到的数据进行对比,根据对比的结果判断在该算法运行过程中覆盖到的指令下,EDMA数据搬移及DSP内核运算是否存在错误,从而实现对SOC芯片的系统级验证功能。与传统的模块级验证相比,实验结果表明该方法可以对EDMA模块的功能验证以及全芯片环境进行查漏补缺,达到更加全面的验证效果。展开更多
OBJECTIVE:To observe the effect of soothing-liver and nourishing-heart acupuncture on selective serotonin reuptake inhibitor(SSRIs) treatment effect onset in patients with depressive disorder and related indicators of...OBJECTIVE:To observe the effect of soothing-liver and nourishing-heart acupuncture on selective serotonin reuptake inhibitor(SSRIs) treatment effect onset in patients with depressive disorder and related indicators of neuroimmunology.METHODS:Overall,126 patients with depressive disorder were randomly divided into a medicine and acupuncture-medicine group using a random number table.Patients were treated for 6 consecutive weeks.The two groups were evaluated by the Montgomery-Asberg Depression Rating Scale(MADRS) and Side Effects Rating Scale(SERS) to assess the effect of the soothing-liver and nourishing-heart acupuncture method on early onset of SSRI treatment effect.Changes in serum 5-hydroxytryptamine(5-HT) and inflammatory cytokines before and after treatment were recorded and compared between the medicine group and the acupuncture-medicine group.RESULTS:The acupuncture-medicine group had significantly lower MADRS scores at weeks 1,2,4,and 6 after treatment compared with the medicine group(P < 0.01).The acupuncture group had significantly lower SERS scores at weeks 1,2,4,and 6 after treatment compared with the medicine group(P < 0.01).At 6 weeks after treatment,serum 5-HT in the acupuncture-medicine group was significantly higher compared with the medicine group(P <0.01).lnterleukin-6(IL-6) in the acupuncture-medicine group was significantly lower than that in the medicine group(P < 0.01),whereas there was no significant difference in IL-1(3 between the groups(P > 0.05).Anti-inflammatory cytokines IL-4 and IL-10 were significantly higher in the acupuncture-medicine group compared with the medicine group(P < 0.01,P < 0.05,respectively).CONCLUSION:The soothing-liver and nourishing-heart acupuncture method can effectively accelerate the onset of SSRI effects when treating depressive disorder and can significantly reduce the adverse reactions of SSRIs.Moreover,acupuncture can enhance serum 5-HT and regulate the balance of pro-inflammatory cytokines and anti-inflammatory cytokines.展开更多
文摘在当下集成电路(integrated circuit, IC)设计规模不断增大的背景下,芯片验证工作所占比重随之日益增加。该研究提出了一种基于C语言源程序实现复杂系统级芯片(system on chip, SOC)系统级验证的方法,其主要思想是以数字信号处理器(digital signal processor, DSP)内核为运算核心,结合图像处理、点云生成算法等算法运算,通过增强型直接内存存取器(enhanced direct memory access, EDMA)进行数据搬移,最后将运算后的数据与通过MATLAB搭建的算法模型运算得到的数据进行对比,根据对比的结果判断在该算法运行过程中覆盖到的指令下,EDMA数据搬移及DSP内核运算是否存在错误,从而实现对SOC芯片的系统级验证功能。与传统的模块级验证相比,实验结果表明该方法可以对EDMA模块的功能验证以及全芯片环境进行查漏补缺,达到更加全面的验证效果。
基金Supported by 2013 Traditional Chinese Medicine Scientific Research Fund of Zhejiang Province(Study on Enhancing Clinical Effect and Neuroimmunology Mechanism with Acupuncture Combined with SSRIs Treating Depressive Disorder,No.2013ZB107)2014 Traditional Chinese Medicine Scientific Research Fund of Zhejiang Province(the Effect of Acupuncture of Soothing-Liver and Nourishing-Heart Method on Early Onset of SSRIs Treating Depressive Disorder and Blood Monoamine Neurotransmitters Related,No.2014ZB090)
文摘OBJECTIVE:To observe the effect of soothing-liver and nourishing-heart acupuncture on selective serotonin reuptake inhibitor(SSRIs) treatment effect onset in patients with depressive disorder and related indicators of neuroimmunology.METHODS:Overall,126 patients with depressive disorder were randomly divided into a medicine and acupuncture-medicine group using a random number table.Patients were treated for 6 consecutive weeks.The two groups were evaluated by the Montgomery-Asberg Depression Rating Scale(MADRS) and Side Effects Rating Scale(SERS) to assess the effect of the soothing-liver and nourishing-heart acupuncture method on early onset of SSRI treatment effect.Changes in serum 5-hydroxytryptamine(5-HT) and inflammatory cytokines before and after treatment were recorded and compared between the medicine group and the acupuncture-medicine group.RESULTS:The acupuncture-medicine group had significantly lower MADRS scores at weeks 1,2,4,and 6 after treatment compared with the medicine group(P < 0.01).The acupuncture group had significantly lower SERS scores at weeks 1,2,4,and 6 after treatment compared with the medicine group(P < 0.01).At 6 weeks after treatment,serum 5-HT in the acupuncture-medicine group was significantly higher compared with the medicine group(P <0.01).lnterleukin-6(IL-6) in the acupuncture-medicine group was significantly lower than that in the medicine group(P < 0.01),whereas there was no significant difference in IL-1(3 between the groups(P > 0.05).Anti-inflammatory cytokines IL-4 and IL-10 were significantly higher in the acupuncture-medicine group compared with the medicine group(P < 0.01,P < 0.05,respectively).CONCLUSION:The soothing-liver and nourishing-heart acupuncture method can effectively accelerate the onset of SSRI effects when treating depressive disorder and can significantly reduce the adverse reactions of SSRIs.Moreover,acupuncture can enhance serum 5-HT and regulate the balance of pro-inflammatory cytokines and anti-inflammatory cytokines.
