Dear Editor,Approximately 4%–10%of upper gastrointestinal(GI)tumors harbor mesenchymal–epithelial transforming factor(MET)amplification,while 50%of individuals with advanced gastric cancer(GC)exhibit MET protein ove...Dear Editor,Approximately 4%–10%of upper gastrointestinal(GI)tumors harbor mesenchymal–epithelial transforming factor(MET)amplification,while 50%of individuals with advanced gastric cancer(GC)exhibit MET protein overexpression[1].Activated MET signaling promotes cancer cell proliferation,survival,and invasion,correlating with poor prognosis in GI malignancies.展开更多
Two-dimensional(2D)semiconductors are emerging as promising candidates for the next-generation nanoelectronics.As a type of unique channel materials,2D semiconducting transition metal dichalcogenides(TMDCs),such as Mo...Two-dimensional(2D)semiconductors are emerging as promising candidates for the next-generation nanoelectronics.As a type of unique channel materials,2D semiconducting transition metal dichalcogenides(TMDCs),such as MoS2 and WS2,exhibit great potential for the state-of-the-art fieldeffect transistors owing to their atomically thin thicknesses,dangling-band free surfaces,and abundant band structures.Even so,the device performances of 2D semiconducting TMDCs are still failing to reach the theoretical values so far,which is attributed to the intrinsic defects,excessive doping,and daunting contacts between electrodes and channels.In this article,we review the up-to-date three strategies for improving the device performances of 2D semiconducting TMDCs:(i)the controllable synthesis of wafer-scale 2D semiconducting TMDCs single crystals to reduce the evolution of grain boundaries,(ii)the ingenious doping of 2D semiconducting TMDCs to modulate the band structures and suppress the impurity scatterings,and(iii)the optimization design of interfacial contacts between electrodes and channels to reduce the Schottky barrier heights and contact resistances.In the end,the challenges regarding the improvement of device performances of 2D semiconducting TMDCs are highlighted,and the further research directions are also proposed.We believe that this review is comprehensive and insightful for downscaling the electronic devices and extending the Moore’s law.展开更多
CONSPECTUS:Among two-dimensional(2D)layered materials,metallic transition metal dichalcogenides(MTMDCs)are emerging as promising candidates in many application aspects(e.g.,electronics,spintronics,and energy related f...CONSPECTUS:Among two-dimensional(2D)layered materials,metallic transition metal dichalcogenides(MTMDCs)are emerging as promising candidates in many application aspects(e.g.,electronics,spintronics,and energy related fields,etc.)in view of their ultrahigh electronic conductivities,newfangled room-temperature ferromagnetism(e.g.,VSe_(2),VTe_(2)),and excellent catalytic activities.Specially,2D TaX_(2) and VX_(2)(X=S,Se,Te)materials stand in a vital place on account of their exotic physical and chemical properties.Notably,the controlled synthesis of such materials is the premise for exploring the aforementioned properties and applications.Among the reported preparation methods,chemical vapor deposition(CVD)is proven to be a promising approach in view of its scalability,simple operation,low cost,etc.This method has been employed to synthesize various 2D layered materials and heterostructures in a well-controlled fashion.Nevertheless,in view of the complicated growth mechanism and process,the CVD growth of ultrathin TaX_(2) and VX_(2) nanosheets/films remains extremely challenging.In addition,the application explorations of 2D TaX_(2) and VX_(2) in the energy related fields and electronic devices are still in the primary stage.In this Account,we review the up-to-date advances regarding the CVD syntheses of 2D TaX_(2) and VX_(2)(e.g.,TaS_(2),TaSe_(2),VS_(2),VSe_(2),and VTe_(2),etc.)and air-stable MTMDCs(e.g.,PtSe2,NiTe2),as well as their multifunctional applications in the energy related fields and electronic devices.First,the CVD growth of TaX_(2) and VX_(2) nanosheets/films with tunable thicknesses/domain sizes and the MTMDCs/semiconducting TMDCs vertical heterostructures are systematically summarized.Second,the application explorations of CVD-synthesized 2D TaX_(2) and VX_(2) as high-performance electrode materials in electrocatalytic hydrogen evolution reaction(HER)and electronic devices are introduced,respectively.Third,the CVD syntheses of 2D MTMDCs with robust environmental stability and novel physical properties(e.g.,semimetal−semiconductor transition,magnetism)are discussed.In the end,the challenges regarding the preparations and multifunctional applications of 2D MTMDCs are highlighted,and the future research directions are also proposed.We believe that this Account is comprehensive and insightful for the CVD syntheses of high-quality 2D MTMDCs materials toward versatile applications.展开更多
基金supported by the Sichuan Science and Technology Program(Grant No.23ZDYF2874)the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(Grant No.ZYJC21043).
文摘Dear Editor,Approximately 4%–10%of upper gastrointestinal(GI)tumors harbor mesenchymal–epithelial transforming factor(MET)amplification,while 50%of individuals with advanced gastric cancer(GC)exhibit MET protein overexpression[1].Activated MET signaling promotes cancer cell proliferation,survival,and invasion,correlating with poor prognosis in GI malignancies.
基金supported by the National Key R&D Program of China(Grant Nos.2018YFA0703700 and 2021YFA1200800)the National Natural Science Foundation of China(Grant Nos.91964203 and 92164103)+1 种基金the Beijing National Laboratory for Molecular Sciences(Grant No.BNLMS202001)the Fundamental Research Funds for the Central Universities(Grant No.2042021kf0029).
文摘Two-dimensional(2D)semiconductors are emerging as promising candidates for the next-generation nanoelectronics.As a type of unique channel materials,2D semiconducting transition metal dichalcogenides(TMDCs),such as MoS2 and WS2,exhibit great potential for the state-of-the-art fieldeffect transistors owing to their atomically thin thicknesses,dangling-band free surfaces,and abundant band structures.Even so,the device performances of 2D semiconducting TMDCs are still failing to reach the theoretical values so far,which is attributed to the intrinsic defects,excessive doping,and daunting contacts between electrodes and channels.In this article,we review the up-to-date three strategies for improving the device performances of 2D semiconducting TMDCs:(i)the controllable synthesis of wafer-scale 2D semiconducting TMDCs single crystals to reduce the evolution of grain boundaries,(ii)the ingenious doping of 2D semiconducting TMDCs to modulate the band structures and suppress the impurity scatterings,and(iii)the optimization design of interfacial contacts between electrodes and channels to reduce the Schottky barrier heights and contact resistances.In the end,the challenges regarding the improvement of device performances of 2D semiconducting TMDCs are highlighted,and the further research directions are also proposed.We believe that this review is comprehensive and insightful for downscaling the electronic devices and extending the Moore’s law.
基金supported by the National Key Research and Development Program of China(No.2018YFA0703700)National Natural Science Foundation of China(Nos.51991340,51991344,51925201,and 52021006)+3 种基金Beijing Natural Science Foundation(No.2192021)Beijing National Laboratory for Molecular Sciences(No.BNLMS202001)the Fundamental Research Funds for the Central Universities(No.2042021kf0029)the Open Research Fund Program of the State Key Laboratory of Low Dimensional Quantum Physics(No.KF202011).
文摘CONSPECTUS:Among two-dimensional(2D)layered materials,metallic transition metal dichalcogenides(MTMDCs)are emerging as promising candidates in many application aspects(e.g.,electronics,spintronics,and energy related fields,etc.)in view of their ultrahigh electronic conductivities,newfangled room-temperature ferromagnetism(e.g.,VSe_(2),VTe_(2)),and excellent catalytic activities.Specially,2D TaX_(2) and VX_(2)(X=S,Se,Te)materials stand in a vital place on account of their exotic physical and chemical properties.Notably,the controlled synthesis of such materials is the premise for exploring the aforementioned properties and applications.Among the reported preparation methods,chemical vapor deposition(CVD)is proven to be a promising approach in view of its scalability,simple operation,low cost,etc.This method has been employed to synthesize various 2D layered materials and heterostructures in a well-controlled fashion.Nevertheless,in view of the complicated growth mechanism and process,the CVD growth of ultrathin TaX_(2) and VX_(2) nanosheets/films remains extremely challenging.In addition,the application explorations of 2D TaX_(2) and VX_(2) in the energy related fields and electronic devices are still in the primary stage.In this Account,we review the up-to-date advances regarding the CVD syntheses of 2D TaX_(2) and VX_(2)(e.g.,TaS_(2),TaSe_(2),VS_(2),VSe_(2),and VTe_(2),etc.)and air-stable MTMDCs(e.g.,PtSe2,NiTe2),as well as their multifunctional applications in the energy related fields and electronic devices.First,the CVD growth of TaX_(2) and VX_(2) nanosheets/films with tunable thicknesses/domain sizes and the MTMDCs/semiconducting TMDCs vertical heterostructures are systematically summarized.Second,the application explorations of CVD-synthesized 2D TaX_(2) and VX_(2) as high-performance electrode materials in electrocatalytic hydrogen evolution reaction(HER)and electronic devices are introduced,respectively.Third,the CVD syntheses of 2D MTMDCs with robust environmental stability and novel physical properties(e.g.,semimetal−semiconductor transition,magnetism)are discussed.In the end,the challenges regarding the preparations and multifunctional applications of 2D MTMDCs are highlighted,and the future research directions are also proposed.We believe that this Account is comprehensive and insightful for the CVD syntheses of high-quality 2D MTMDCs materials toward versatile applications.
