Both batch-to-batch(B2 B)and roll-to-roll(R2 R)processes can be used for mass production of graphene films.Because of the simplicity of equipment,the B2 B process is more commonly used in laboratory research.In contra...Both batch-to-batch(B2 B)and roll-to-roll(R2 R)processes can be used for mass production of graphene films.Because of the simplicity of equipment,the B2 B process is more commonly used in laboratory research.In contrast,the R2 R process is more industrially preferred because it is easier to automate and more compatible with the subsequent transfer process.Up to now,the research on R2 R process has mainly focused on the design of the reactor or the loading configuration,but the in-depth understanding on the growth kinetics is lack.In this paper,we investigated the evolution of graphene growth and revealed that the graphene domain density grown by the R2 R process was larger than that by the B2 B process with the same reaction parameters,which was attributed to different reaction profiles between the two processes.Furthermore,the defective graphene could be healed with elongated reaction time.With the optimized R2 R process,graphene films with quality comparable to those grown by conventional B2 B process could be achieved.Our research will promote the development of the mass-production technique for graphene films.展开更多
Cancer drug resistance has become one of the main challenges for the failure of chemotherapy,greatly limiting the selection and use of anticancer drugs and dashing the hopes of cancer patients.The emergence of supramo...Cancer drug resistance has become one of the main challenges for the failure of chemotherapy,greatly limiting the selection and use of anticancer drugs and dashing the hopes of cancer patients.The emergence of supramolecular host-vip nanosystems has brought the field of supramolecular chemistry into the nanoworld,providing a potential solution to this challenge.Compared with conventional chemotherapeutic platforms,supramolecular host-vip nanosystems can reverse cancer drug resistance by increasing drug uptake,reducing drug efflux,activating drugs,and inhibiting DNA repair.Herein,we summarize the research progress of supramolecular host-vip nanosystems for overcoming cancer drug resistance and discuss the future research direction in this field.It is hoped that this review will provide more positive references for overcoming cancer drug resistance and promoting the development of supramolecular host-vip nanosystems.展开更多
基金supported by the National Natural Science Foundation of China(51772043,51802036)Shenzhen Science and Technology Program((2021)105)。
文摘Both batch-to-batch(B2 B)and roll-to-roll(R2 R)processes can be used for mass production of graphene films.Because of the simplicity of equipment,the B2 B process is more commonly used in laboratory research.In contrast,the R2 R process is more industrially preferred because it is easier to automate and more compatible with the subsequent transfer process.Up to now,the research on R2 R process has mainly focused on the design of the reactor or the loading configuration,but the in-depth understanding on the growth kinetics is lack.In this paper,we investigated the evolution of graphene growth and revealed that the graphene domain density grown by the R2 R process was larger than that by the B2 B process with the same reaction parameters,which was attributed to different reaction profiles between the two processes.Furthermore,the defective graphene could be healed with elongated reaction time.With the optimized R2 R process,graphene films with quality comparable to those grown by conventional B2 B process could be achieved.Our research will promote the development of the mass-production technique for graphene films.
基金We thank the National Natural Science Foundation of China(22101043)the Fundamental Research Funds for the Central Universities(N2205013,N232410019)+1 种基金the Open Fund of Guangdong Provincial Key Laboratory of Functional Supramolecular Coordination Materials and Applications(2022A07)Northeastern University for financial support.
文摘Cancer drug resistance has become one of the main challenges for the failure of chemotherapy,greatly limiting the selection and use of anticancer drugs and dashing the hopes of cancer patients.The emergence of supramolecular host-vip nanosystems has brought the field of supramolecular chemistry into the nanoworld,providing a potential solution to this challenge.Compared with conventional chemotherapeutic platforms,supramolecular host-vip nanosystems can reverse cancer drug resistance by increasing drug uptake,reducing drug efflux,activating drugs,and inhibiting DNA repair.Herein,we summarize the research progress of supramolecular host-vip nanosystems for overcoming cancer drug resistance and discuss the future research direction in this field.It is hoped that this review will provide more positive references for overcoming cancer drug resistance and promoting the development of supramolecular host-vip nanosystems.
