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双季戊四醇镧类稀土金属醇盐的制备及其在聚氯乙烯热稳定剂中的应用
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作者 陈明光 曹鸿璋 +2 位作者 田林峰 李德刚 罗果萍 《高分子材料科学与工程》 北大核心 2025年第4期77-87,共11页
采用双季戊四醇、马来酸和醋酸镧为原料,合成了2种稀土热稳定剂,即双季戊四醇镧金属醇盐(Di-PE-La)和马来酸双季戊四醇酯镧金属盐(DMPE-La)。一方面,考察了其对PVC热稳定性能的影响,结果显示,与Di-PE-La相比,DMPE-La单独使用时具有更好... 采用双季戊四醇、马来酸和醋酸镧为原料,合成了2种稀土热稳定剂,即双季戊四醇镧金属醇盐(Di-PE-La)和马来酸双季戊四醇酯镧金属盐(DMPE-La)。一方面,考察了其对PVC热稳定性能的影响,结果显示,与Di-PE-La相比,DMPE-La单独使用时具有更好的初期着色性能和长期热稳定性能,且能在保持拉伸强度的同时提高样片的断裂伸长率。另一方面,理论计算和热稳定作用机理研究表明,2种稀土热稳定剂都可以取代PVC链上不稳定的氯原子来改善PVC的初期着色性,并能吸收HCl来改善PVC的长期热稳定性,2种稀土热稳定剂中的羟基还能络合ZnCl_(2),避免ZnCl_(2)的游离和催化PVC降解。 展开更多
关键词 双季戊四醇 稀土金属醇盐 聚氯乙烯 热稳定剂 热稳定机理
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Novel optimization techniques for underwater wireless optical communication links:using Monte Carlo simulation
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作者 Intesar Ramley Hamdah MAlzayed +2 位作者 Yas Al-Hadeethi Abeer ZBarasheed mingguang chen 《Defence Technology(防务技术)》 2025年第8期386-411,共26页
The Underwater Communication Link(UCL)is a crucial component of Underwater Wireless Optical Communication(UWOC)systems,requiring optimised design to mitigate the high power attenuation inherent in seawater.To ensure t... The Underwater Communication Link(UCL)is a crucial component of Underwater Wireless Optical Communication(UWOC)systems,requiring optimised design to mitigate the high power attenuation inherent in seawater.To ensure the reliability of an optimal UCL design,it is essential to account for the three primary scattering regimes:forward scattering(FSC),backward scattering(BSC),and isotropic scattering(ISC)in seawater channels.This study introduces a new photon-tracking model based on a discrete equation,facilitating Monte Carlo Simulation(MCS)to evaluate how different scattering regimes influence received photon distribution.Three distinct Scattering Regime Contribution Weight(SRCW)probability sets were employed,each representing different UCL operational configurations dominated by specific scattering regimes.The proposed modeling approach enables a comprehensive assessment of the temporal characteristics of received optical pulses,channel loss,and time spread-ultimately defining the optimal UCL design parameters.The key findings of this study include:(1)Enhancing the FSC regime dominance leads to a quasi-light waveguide effect over link spans and small Fields of View(FOV)<25°,significantly improving channel performance in Harbor seawater compared to Coastal seawater.(2)A well-designed UCL with a small FOV(<25°)can minimise channel loss and time spread,ensuring high capacity and efficient performance in both Coastal and Harbor seawaters.(3)When BSC and ISC contributions exceed FSC dominance,the received optical pulse undergoes significant temporal broadening,particularly for larger FOV angles(>25°)and extended link spans.(4)The developed novel MCS-based discrete equation provides a simple yet robust model for simulating photon propagation in both homogeneous and inhomogeneous underwater channels.These insights contribute to developing more efficient and reliable UCL designs with military standards by enhancing UWOC system performance over a longer linkspan for a given limited optical power across various underwater environments. 展开更多
关键词 Channel gain/loss Channel impulse response(CIR) Central limit theorem(CLT) Channel time spread Field of view(FOV) Monte Carlo simulation(MCS) Underwater wireless optical communication(UWOC)
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牡蛎肽通过NF-κB/iNOS信号通路改善肝纤维化 被引量:4
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作者 邓凯翔 彭经宙 +6 位作者 张美泉 林慧娟 王小华 何道兴 朱俊明 陈明光 黄津 《Journal of Chinese Pharmaceutical Sciences》 CAS CSCD 2023年第6期435-445,共11页
本文研究探讨牡蛎肽(OP)改善肝纤维化的机制可能是通过NF-κB/iNOS信号通路。将50只雄性SD大鼠采用随机数字表法随机分为5组:对照组、模型组、低剂量(0.5 g/kg) OP组、中剂量(1.0 g/kg) OP组、高剂量(2.0 g/kg) OP组,每组10只。皮下注射... 本文研究探讨牡蛎肽(OP)改善肝纤维化的机制可能是通过NF-κB/iNOS信号通路。将50只雄性SD大鼠采用随机数字表法随机分为5组:对照组、模型组、低剂量(0.5 g/kg) OP组、中剂量(1.0 g/kg) OP组、高剂量(2.0 g/kg) OP组,每组10只。皮下注射50%四氯化碳(CCl4)建立肝纤维化大鼠模型6周。结果发现,OP治疗组中,CCl4诱导的肝纤维化大鼠肝脏中Ⅰ型胶原、Ⅲ型胶原和TGF-β1表达水平均显著低于模型组(P<0.05)。OP可以下调大鼠的肝组织NF-κB和iNOS的表达,可能是通过介导NF-κB/iNOS信号通路改善大鼠肝纤维化。 展开更多
关键词 肝纤维化 牡蛎肽 核因子-ΚB 诱导型一氧化氮合酶
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Highly antibacterial rGO/Cu2O nanocomposite from a biomass precursor:Synthesis,performance,and mechanism 被引量:4
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作者 mingguang chen Zhi Li Long chen 《Nano Materials Science》 CAS 2020年第2期172-179,共8页
Reduced graphene oxide(rGO)has been widely used to fabricate electronics,sensors,photodetectors,and in other applications.However,the antibacterial performance of pristine rGO is relatively weak.The application of rGO... Reduced graphene oxide(rGO)has been widely used to fabricate electronics,sensors,photodetectors,and in other applications.However,the antibacterial performance of pristine rGO is relatively weak.The application of rGO in biomedical devices,smart food packaging,and water desalination membranes requires further improvement of rGO’s antibacterial abilities.Copper(I)oxide(Cu2O)is an effective antibacterial agent,which denatures protein and enhances the permeability of cell membranes.In this work,we report a simple method of synthesizing a highly antibacterial rGO/Cu2O nanocomposite from cellulose acetate,a derivative of abundant natural cellulose.The synthesized rGO/Cu2O nanocomposite was thoroughly characterized by Raman spectroscopy,X-ray powder diffraction(XRD),X-ray photoelectron spectroscopy(XPS),atomic force microscopy(AFM),scanning electron microscopy(SEM),high-resolution transmission electron microscopy(HRTEM),and scanning transmission electron microscopy(STEM).Then,the antibacterial abilities of rGO/Cu2O nanocomposite were evaluated and a bactericidal mechanism was revealed from the molecular biology perspective.Results indicate that our synthesized rGO/Cu2O nanocomposite owns strong antibacterial activity,mainly stemming from the uniformly incorporated Cu2O nanocrystals with a lateral size of 5–40 nm. 展开更多
关键词 Cellulose acetate rGO/Cu2O nanocomposite ANTIBACTERIAL
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Effects of Activating Blood Circulation to Resolve Blood Stasis and Glucosamine Capsules Therapy on the Expression of Matrix Metalloproteinase in Post-traumatic Knee Osteoarthritis
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作者 mingguang chen Shiqiang chen +5 位作者 Ning YANG Jin YANG Yingang LI Xiaoxia CAO Chunfeng CHANG Xuelan WU 《Medicinal Plant》 CAS 2019年第3期77-81,86,共6页
[Objectives] To observe the clinical effects of activating blood circulation to resolve blood stasis and glucosamine hydrochloride capsules therapy on post-traumatic knee osteoarthritis treatment,to measure the expres... [Objectives] To observe the clinical effects of activating blood circulation to resolve blood stasis and glucosamine hydrochloride capsules therapy on post-traumatic knee osteoarthritis treatment,to measure the expression of matrix metalloproteinase in post-traumatic knee osteoarthritis patients before and after treatment,and to explore its relevant molecular mechanisms. [Methods]A total of 60 patients with posttraumatic knee osteoarthritis in early stage in Affiliated Hospital of Shannxi University of Chinese Medicine from January 2015 to December2017 were selected and randomly divided into the control group( n = 30) and the observation group( n = 30). The control group was given oral administration of glucosamine hydrochloride capsules for 6 courses of the treatment. The observation group was using the activating blood circulation to resolve blood stasis therapy for 6 courses of treatment. The recovery of traumatic knee osteoarthritis and the symptom of traditional Chinese medicine( TCM) in 2 groups was compared before and after treatment. The symptoms and the quantitative assessment rating scale of knee osteoarthritis,the pain index of knee and the TCM symptom scores were recorded in both groups. And the synovial fluid and serum of patients were collected to detect the expression of matrix metalloproteinase. [Results]The symptoms and the quantitative assessment rating scale of knee osteoarthritis,the pain index of knee and TCM symptom scores of the 2 groups in the 1 st week,the 12 th week and the 24 th week after the treatment were significantly lower than those before the treatment,and the difference was statistically significant( P < 0. 05). Two therapeutic methods had certain therapeutic effects on the recovery from traumatic knee osteoarthritis,and could significantly improve the TCM syndrome. There were better therapeutic effects on oral decoction of traditional Chinese medicine than oral glycosaminoglycans hydrochloride capsules on treating traumatic knee osteogenesis( P < 0. 05). The expression level of MMP3 was decreased significantly in both groups( P <0. 001),while the expression level of MMP13 had no significant change in both groups( P >0. 05). The expression level of MMP1 was decreased significantly in the observation group( P < 0. 001),but there was no significant change in the control group after treatment( P >0. 05). [Conclusions]Two treatment methods have been effective in this clinical study. We found that the expression level of MMP3 was decreased significantly after treatment in 2 therapies,which can be clinically applied. 展开更多
关键词 Activating BLOOD CIRCULATION to RESOLVE BLOOD stasis GLUCOSAMINE hydrochloride Osteoarthritis Knee joint MATRIX metalloproteinases-1 MATRIX metalloproteinases-3 MATRIX metalloproteinases-13 Therapeutic effects
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