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改良带角膜缘干细胞的游离结膜瓣移植术治疗翼状胬肉 被引量:7
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作者 范可顺 邵新香 +1 位作者 司明宇 张莹 《国际眼科杂志》 CAS 北大核心 2022年第3期517-520,共4页
目的:探讨改良带角膜缘干细胞的游离结膜瓣移植术治疗翼状胬肉的临床疗效及对泪膜功能的影响。方法:病例对照研究。将我院2017-03/2021-03收治的60例60眼翼状胬肉患者,按随机数字表法分为对照组和观察组,各30例30眼,对照组给予翼状胬肉... 目的:探讨改良带角膜缘干细胞的游离结膜瓣移植术治疗翼状胬肉的临床疗效及对泪膜功能的影响。方法:病例对照研究。将我院2017-03/2021-03收治的60例60眼翼状胬肉患者,按随机数字表法分为对照组和观察组,各30例30眼,对照组给予翼状胬肉切除联合羊膜移植术治疗,观察组给予翼状胬肉切除联合改良带角膜缘干细胞的游离结膜瓣移植术治疗,治疗周期均为21d。比较两组患者临床疗效、手术时间、角膜创面修复时间,术前和术后1、3mo的干眼评分、泪膜破裂时间值和基础泪液分泌试验值以及不良反应发生情况。结果:观察组临床治疗总有效率高于对照组(χ^(2)=5.963,P=0.015),观察组手术时间长于对照组(t=-2.643,P<0.05),角膜创面修复时间短于对照组(t=2.182,P<0.05)。两组患者在术后1、3mo,干眼评分与术前比较均下降(均P<0.05),且观察组与对照组比较有差异(t=2.082、3.956,均P<0.05)。术后1、3mo泪膜破裂时间与术前比较均升高(均P<0.05),且观察组与对照组比较有差异(t=4.245、2.070,均P<0.05);术后1、3mo基础泪液分泌试验值与术前比较均升高(均P<0.05),且观察组与对照组比较有差异(t=2.076、2.223,均P<0.05)。两组患者的并发症发生率比较差异无统计学意义(P=0.572)。结论:改良带角膜缘干细胞的游离结膜瓣移植术可有效改善翼状胬肉患者临床症状,改善泪膜功能,利于术后角膜创面修复,不良反应发生率较低。 展开更多
关键词 翼状胬肉 角膜缘干细胞 羊膜 泪膜 移植
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伴有面转代偿头位的先天性下直肌麻痹临床特征与手术治疗(英文)
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作者 司明宇 邵新香 范可顺 《国际眼科杂志》 CAS 北大核心 2019年第4期538-546,共9页
目的:描述伴有面转代偿头位的先天性单纯下直肌麻痹患者的临床表现,并分析其手术治疗效果。方法:回顾性分析2014-05/2018-07伴有明显面转代偿头位的先天性下直肌麻痹患者,手术前后患者面转程度的变化借助骨科量角器来检查,垂直、水平斜... 目的:描述伴有面转代偿头位的先天性单纯下直肌麻痹患者的临床表现,并分析其手术治疗效果。方法:回顾性分析2014-05/2018-07伴有明显面转代偿头位的先天性下直肌麻痹患者,手术前后患者面转程度的变化借助骨科量角器来检查,垂直、水平斜视度变化通过三棱镜交替遮盖试验来测量,旋转斜视度变化通过眼底对眼球客观旋转状态评估。下直肌缩短术是主要治疗方案。结果:在15例研究对象中,有13例行下直肌缩短术或者联合上直肌后徙术术后疗效好,下直肌运动不足明显改善,眼球运动协调,以面转为主的代偿头位消失,垂直、水平、旋转斜视得到矫正;并得出:每缩短1 mm下直肌可矫正1.54±0.93°内旋斜视。而行下斜肌断腱术治疗的垂直斜视度小的患者,面转改善不理想,仍遗留眼球运动不协调。结论:先天性单纯的下直肌麻痹以面转代偿头位为主,下直肌缩短术治疗效果好,轻度的过矫及欠矫不影响手术疗效。 展开更多
关键词 先天性下直肌麻痹 面转 代偿头位 下直肌缩短术
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Mindfulness-based online intervention on mental health and quality of life among COVID-19 patients in China: an intervention design 被引量:2
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作者 ming-yu si Wei-Jun Xiao +11 位作者 Chen Pan Hao Wang Yi-Man Huang Jun Lian Winnie W.S.Mak Zhi-Wei Leng Xiao-You Su Qiu-PingTang Yu Jiang Lu-Zhao Feng Wei-Zhong Yang Chen Wang 《Infectious Diseases of Poverty》 SCIE 2021年第3期62-71,共10页
Background:COVID-19 can lead to increased psychological symptoms such as post-traumatic stress disorder(PTSD),depression,and anxiety among patients with COVID-19.Based on the previous mindfulness-based interventions p... Background:COVID-19 can lead to increased psychological symptoms such as post-traumatic stress disorder(PTSD),depression,and anxiety among patients with COVID-19.Based on the previous mindfulness-based interventions proved to be effective,this protocol reports a design of a randomized controlled trial aiming to explore the efficacy and possible mechanism of a mindful living with challenge(MLWC)intervention developed for COVID-19 survivors in alleviating their psychological problems caused by both the disease and the pandemic.Methods:In April 2021,more than 1600 eligible participants from Hubei Province of China will be assigned 1:1 to an online MLWC intervention group or a waitlist control group.All participants will be asked to complete online questionnaires at baseline,post-program,and 3-month follow-up.The differences of mental health status(e.g.PTSD)and physical symptoms including fatigue and sleeplessness between the COVID-19 survivors who receiving the online MLWC intervention and the control group will be assessed.In addition,the possible mediators and moderators of the link between the MLWC intervention and target outcomes will be evaluated by related verified scales,such as the Five Facets Mindfulness Questionnaire.Data will be analyzed based on an intention-to-t「eat approach,and SPSS software will be used to perform statistical analysis.Discussion:The efficacy and potential mechanism of MLWC intervention in improving the quality of life and psychological status of COVID-19 survivors in China are expected to be reported.Findings from this study will shed light on a novel and feasible model in improving the psychological well-being of people during such public health emergencies.Trial registration Chinese ClinicalTrial Registry(ChiCTR),ChiCTR2000037524;Registered on August 29,2020,http://www.chictr.org.cn/showproj.aspx?proj=60034. 展开更多
关键词 COVID-19 Internet Mindfulness-based intervention Mental health Randomized controlled trial China
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Psychological impact of COVID-19 on medical care workers in China 被引量:5
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作者 ming-yu si Xiao-You Su +9 位作者 Yu Jiang Wen-Jun Wang Xiao-Fen Gu Li Ma Jing Li Shao-Kai Zhang Ze-Fang Ren Ran Ren Yuan-Li Liu You-Lin Qiao 《Infectious Diseases of Poverty》 SCIE 2020年第4期163-163,共1页
Background Medical care workers experienced unprecedented levels of workload and pressure since the outbreak of coronavirus disease 2019(COVID-19).Little is known about its exact impact on medical care workers and rel... Background Medical care workers experienced unprecedented levels of workload and pressure since the outbreak of coronavirus disease 2019(COVID-19).Little is known about its exact impact on medical care workers and related factors in China.This study aims to identify the psychological impact of COVID-19 on medical care workers in China.Methods From February 23 to March 5,2020,a cross-sectional survey was conducted among 863 medical care workers from seven provinces in China using standard questionnaires measuring adverse psychological outcomes including Impact of Event Scale-6(IES-6),Depression,Anxiety and Stress Scale(DASS)and related psychosocial factors like perceived threat,social support and coping strategies.Exploratory Factor analysis was performed to identify the dimensions of perceived threat by study participants.Multivariate regression was used to examine the determinants of adverse psychological outcomes.Results Posttraumatic stress(PTS)were prevalent in this sample of health care professionals,and 40.2%indicated positive screens for significant posttraumatic stress disorder symptoms.The proportion of having mild to extremely severe symptoms of depression,anxiety and stress were 13.6,13.9 and 8.6%,respectively.Perceived threat and passive coping strategies were positively correlated to PTS and DASS scores,while perceived social support and active coping strategies were negatively correlated to DASS scores.Nurses were more likely to be anxious than others among medical care workers during the COVID-19 epidemic.Conclusions Adverse psychological symptoms were prevalent among medical care workers in China during the COVID-19 epidemic.Screening for adverse psychological outcomes and developing corresponding preventive measures would be beneficial in decreasing negative psychological outcomes. 展开更多
关键词 COVID-19 Medical care worker China PSYCHOLOGICAL Posttraumatic stress disorder DEPRESSION ANXIETY STRESS
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