Objective To compare the conjoint effect of enteral nutrition (EN) and parenteral nutrition (PN)with single EN or PN on immune function, nutritional status, complications and clinical outcomes of patientswith severe t...Objective To compare the conjoint effect of enteral nutrition (EN) and parenteral nutrition (PN)with single EN or PN on immune function, nutritional status, complications and clinical outcomes of patientswith severe traumatic brain injury (STBI).Methods A prospective randomized control trial was carried out from January 2009 to May 2012 inNeurological Intensive Care Unit (NICU). Patients of STBI who met the enrolment criteria (Glasgow ComaScale score 6~8; Nutritional Risk Screening ≥3) were randomly divided into 3 groups and were administratedEN, PN or EN＋PN treatments respectively. The indexes of nutritional status, immune function,complications and clinical outcomes were examined and compared statistically.展开更多
Meningioma is a common intracranial tumor in adults.Pediatric cases account for approximately 1.5% of all intracranial meningiomas,and very few cases show malignant histological features.Primary pediatric malignant me...Meningioma is a common intracranial tumor in adults.Pediatric cases account for approximately 1.5% of all intracranial meningiomas,and very few cases show malignant histological features.Primary pediatric malignant meningioma in the cerebellopontine angle is extremely uncommon.Herein,we report a 2-yearold girl with malignant meningioma in the cerebellopontine angle.The clinical features,diagnosis,and treatment protocol are discussed.展开更多
Objective To clarify the clinical features,therapeutic method and outcomes of the primary endodermal sinus tumors(ESTs)in the posterior cranial fossa.Methods The English literatures on EST in the posterior cranial fos...Objective To clarify the clinical features,therapeutic method and outcomes of the primary endodermal sinus tumors(ESTs)in the posterior cranial fossa.Methods The English literatures on EST in the posterior cranial fossa were retrieved from PubMed and reviewed.And a 4-year-old boy diagnosed with EST in our hospital was reported.The clinical manifestations,therapy,pathologic features,and prognosis of these cases were analyzed.Results Only seven cases of the ESTs in the posterior cranial fossa were enrolled in this review,including six cases searched from the PubMed and one case from our hospital.Six patients were boy and one patient’s gender was not available from the report.Ages ranged from 1 to 5 years(mean 3.14 years).The mean tumor size in our cohort was 4.4 cm.Six cases came from East Asia.Schiller-Duval bodies were found in all seven neoplasms.All tumors were positive for alpha-fetoprotein.The alpha-fetoprotein level in serum was increased to a very high level before therapy and depressed quickly after the effective chemotherapy.The mean follow-up time was 24.4 months(range 5-52 months).Six tumors were totally removed,and four of them recurred.Three cases died including one whose tumor was partially removed.Conclusions The serum alpha-fetoprotein level is well correlated with the severity of the tumor.A combination of operation and chemotherapy might be the effective management for EST in the posterior cranial fossa.The prognosis of extragonadal intracranial EST is poor.展开更多
INFLAMMATORY myofibroblastic tumor（IMT）,alsoknown as inflammatory pseudotumor or plasma cellgranulomas,is an uncommon fibro-inflammatorylesion which is composed of inflammatory cells andmyofibroblastic spindle cells...INFLAMMATORY myofibroblastic tumor（IMT）,alsoknown as inflammatory pseudotumor or plasma cellgranulomas,is an uncommon fibro-inflammatorylesion which is composed of inflammatory cells andmyofibroblastic spindle cells.1Its pathogenesis is still un-known.The tumor commonly occurs in the lung,upperrespiratory tract,live,orbit,abdominal membrane,retro-peritoneum,and genitourinary tract.2-4It rarely involvesthe central nerve system,5,展开更多
LIMAS and Tio1 proposed the term meningeal melanocytoma first time in 1972 to describe a primary melanotic tumor of the leptomeninges with prolonged clinical course and benign histology.Meningeal melanocytoma of the c...LIMAS and Tio1 proposed the term meningeal melanocytoma first time in 1972 to describe a primary melanotic tumor of the leptomeninges with prolonged clinical course and benign histology.Meningeal melanocytoma of the central nervous system is rare and benign primary meningeal melanocytoma (PMM) is more exceptional,and also less usual than the malignant types.2 This rare tumor falls under the subclassification of primary melanocytic lesions in the World Health Organization's classification of central nervous system tumors.3 PMM located in the foramen magnum region is an unusual cause of bulbus medullae and fourth ventricle compression.Here we report a 48-year-old man with a PMM which is located in the foramen magnum inducing supratentorial obstructive hydrocephalus.展开更多
Background: The information about paediatric meningiomas is poor. The purpose of this study was to review the clinical characteristic, treatment considerations and prognosis of paediatric meningiomas. Methods: We retr...Background: The information about paediatric meningiomas is poor. The purpose of this study was to review the clinical characteristic, treatment considerations and prognosis of paediatric meningiomas. Methods: We retrospectively reviewed a series of 32 paediatric patients with meningiomas who received surgical resection at the Affiliated Hospital of Qingdao University between January 2002 and December 2010. Results: The study group included 17 boys and 15 girls (range: 2–18 years, mean: 13.7 years). Thirteen patients were in the first decade of life and 19 patients were in the second decade. The most common symptoms were headache (33. 3%) and epilepsy (25%), followed by cranial nerve dysfunction: distortion of commissure, vision disorder, acoasma and unconsciousness. The size of lesions was ranged 35–65 mm (mean 42.3 mm). Of these 32 patients, 16 were revealed WHO class I meningiomas, 5 were WHO class II, and 11 manifested WHO class III. Nine of 32 patients met the criteria that had tumor recurrence within follow-up. Conclusions: Paediatric meningiomas usually have larger size, higher pathologic grade and unusual location. The influential factors for recurrence include lesion location, histological features and extent of removal. Complete tumor resection is the best choice to prevent recurrence and improve the prognosis.展开更多
基金Supported by the Natural Science Foundation of Shandong province(Y2008C35)Technology Supporting Program of Qingdao(12-1-3-5-(1)-nsh)
文摘Objective To compare the conjoint effect of enteral nutrition (EN) and parenteral nutrition (PN)with single EN or PN on immune function, nutritional status, complications and clinical outcomes of patientswith severe traumatic brain injury (STBI).Methods A prospective randomized control trial was carried out from January 2009 to May 2012 inNeurological Intensive Care Unit (NICU). Patients of STBI who met the enrolment criteria (Glasgow ComaScale score 6~8; Nutritional Risk Screening ≥3) were randomly divided into 3 groups and were administratedEN, PN or EN＋PN treatments respectively. The indexes of nutritional status, immune function,complications and clinical outcomes were examined and compared statistically.
文摘Meningioma is a common intracranial tumor in adults.Pediatric cases account for approximately 1.5% of all intracranial meningiomas,and very few cases show malignant histological features.Primary pediatric malignant meningioma in the cerebellopontine angle is extremely uncommon.Herein,we report a 2-yearold girl with malignant meningioma in the cerebellopontine angle.The clinical features,diagnosis,and treatment protocol are discussed.
文摘Objective To clarify the clinical features,therapeutic method and outcomes of the primary endodermal sinus tumors(ESTs)in the posterior cranial fossa.Methods The English literatures on EST in the posterior cranial fossa were retrieved from PubMed and reviewed.And a 4-year-old boy diagnosed with EST in our hospital was reported.The clinical manifestations,therapy,pathologic features,and prognosis of these cases were analyzed.Results Only seven cases of the ESTs in the posterior cranial fossa were enrolled in this review,including six cases searched from the PubMed and one case from our hospital.Six patients were boy and one patient’s gender was not available from the report.Ages ranged from 1 to 5 years(mean 3.14 years).The mean tumor size in our cohort was 4.4 cm.Six cases came from East Asia.Schiller-Duval bodies were found in all seven neoplasms.All tumors were positive for alpha-fetoprotein.The alpha-fetoprotein level in serum was increased to a very high level before therapy and depressed quickly after the effective chemotherapy.The mean follow-up time was 24.4 months(range 5-52 months).Six tumors were totally removed,and four of them recurred.Three cases died including one whose tumor was partially removed.Conclusions The serum alpha-fetoprotein level is well correlated with the severity of the tumor.A combination of operation and chemotherapy might be the effective management for EST in the posterior cranial fossa.The prognosis of extragonadal intracranial EST is poor.
文摘INFLAMMATORY myofibroblastic tumor（IMT）,alsoknown as inflammatory pseudotumor or plasma cellgranulomas,is an uncommon fibro-inflammatorylesion which is composed of inflammatory cells andmyofibroblastic spindle cells.1Its pathogenesis is still un-known.The tumor commonly occurs in the lung,upperrespiratory tract,live,orbit,abdominal membrane,retro-peritoneum,and genitourinary tract.2-4It rarely involvesthe central nerve system,5,
文摘LIMAS and Tio1 proposed the term meningeal melanocytoma first time in 1972 to describe a primary melanotic tumor of the leptomeninges with prolonged clinical course and benign histology.Meningeal melanocytoma of the central nervous system is rare and benign primary meningeal melanocytoma (PMM) is more exceptional,and also less usual than the malignant types.2 This rare tumor falls under the subclassification of primary melanocytic lesions in the World Health Organization's classification of central nervous system tumors.3 PMM located in the foramen magnum region is an unusual cause of bulbus medullae and fourth ventricle compression.Here we report a 48-year-old man with a PMM which is located in the foramen magnum inducing supratentorial obstructive hydrocephalus.
文摘Background: The information about paediatric meningiomas is poor. The purpose of this study was to review the clinical characteristic, treatment considerations and prognosis of paediatric meningiomas. Methods: We retrospectively reviewed a series of 32 paediatric patients with meningiomas who received surgical resection at the Affiliated Hospital of Qingdao University between January 2002 and December 2010. Results: The study group included 17 boys and 15 girls (range: 2–18 years, mean: 13.7 years). Thirteen patients were in the first decade of life and 19 patients were in the second decade. The most common symptoms were headache (33. 3%) and epilepsy (25%), followed by cranial nerve dysfunction: distortion of commissure, vision disorder, acoasma and unconsciousness. The size of lesions was ranged 35–65 mm (mean 42.3 mm). Of these 32 patients, 16 were revealed WHO class I meningiomas, 5 were WHO class II, and 11 manifested WHO class III. Nine of 32 patients met the criteria that had tumor recurrence within follow-up. Conclusions: Paediatric meningiomas usually have larger size, higher pathologic grade and unusual location. The influential factors for recurrence include lesion location, histological features and extent of removal. Complete tumor resection is the best choice to prevent recurrence and improve the prognosis.
