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Optimisation of mobile intelligent terminal data pre-processing methods for crowd sensing
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作者 min huang Yuefan Zeng +1 位作者 Lina Chen Bo Sun 《CAAI Transactions on Intelligence Technology》 2018年第2期101-113,共13页
Sensor data pre-processing is an essential phase of crowd sensing application. Existing studies do not effectively solve the problem, and there still exist various sensor data pre-processing optimisation problems at t... Sensor data pre-processing is an essential phase of crowd sensing application. Existing studies do not effectively solve the problem, and there still exist various sensor data pre-processing optimisation problems at the acquisition end in crowd-sensing process. This study presents an improved sliding average method to achieve data compression and reduce the time complexity by using a dynamic window with improved processing time. Through adopting locally sorting and gradient change of the filter window, an improved extremum median filtering method is proposed to relieve the time- consuming problem when denoising high pixel images. A transmission strategy for optimisation is also proposed, in which only the demarcation points of each group of data and the data points with large differences when comparing with the demarcation points are recorded. This strategy reduces the storage pressure and the amount of data transmission of mobile terminal and improves the efficiency of data transmission. The experimental results show that their methods have higher speed and lower cost, and thus they can run better in crowd-sensing environment. 展开更多
关键词 传感器 数据预处理 智能技术 发展现状
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MewCDNet: A Wavelet-Based Multi-Scale Interaction Network for Efficient Remote Sensing Building Change Detection
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作者 Jia Liu Hao Chen +5 位作者 Hang Gu Yushan Pan Haoran Chen Erlin Tian min huang Zuhe Li 《Computers, Materials & Continua》 2026年第1期687-710,共24页
Accurate and efficient detection of building changes in remote sensing imagery is crucial for urban planning,disaster emergency response,and resource management.However,existing methods face challenges such as spectra... Accurate and efficient detection of building changes in remote sensing imagery is crucial for urban planning,disaster emergency response,and resource management.However,existing methods face challenges such as spectral similarity between buildings and backgrounds,sensor variations,and insufficient computational efficiency.To address these challenges,this paper proposes a novel Multi-scale Efficient Wavelet-based Change Detection Network(MewCDNet),which integrates the advantages of Convolutional Neural Networks and Transformers,balances computational costs,and achieves high-performance building change detection.The network employs EfficientNet-B4 as the backbone for hierarchical feature extraction,integrates multi-level feature maps through a multi-scale fusion strategy,and incorporates two key modules:Cross-temporal Difference Detection(CTDD)and Cross-scale Wavelet Refinement(CSWR).CTDD adopts a dual-branch architecture that combines pixel-wise differencing with semanticaware Euclidean distance weighting to enhance the distinction between true changes and background noise.CSWR integrates Haar-based Discrete Wavelet Transform with multi-head cross-attention mechanisms,enabling cross-scale feature fusion while significantly improving edge localization and suppressing spurious changes.Extensive experiments on four benchmark datasets demonstrate MewCDNet’s superiority over comparison methods:achieving F1 scores of 91.54%on LEVIR,93.70%on WHUCD,and 64.96%on S2Looking for building change detection.Furthermore,MewCDNet exhibits optimal performance on the multi-class⋅SYSU dataset(F1:82.71%),highlighting its exceptional generalization capability. 展开更多
关键词 Remote sensing change detection deep learning wavelet transform MULTI-SCALE
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Self-assembly synthesis of SnNb2O6/amino-functionalized graphene nanocomposite as high-rate anode materials for sodium-ion batteries 被引量:6
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作者 min huang Ji-Xin Liu +2 位作者 Peng huang Hai Hu Chao Lai 《Rare Metals》 SCIE EI CAS CSCD 2021年第2期425-432,共8页
A two-dimensional(2 D)SnNb_(2)O_(6)/amino-functionalized graphene(En-RGO)nanocomposite with a representative 2 D-2 D architecture has been constructed by an easy self-assembly approach and firstly investigated as anod... A two-dimensional(2 D)SnNb_(2)O_(6)/amino-functionalized graphene(En-RGO)nanocomposite with a representative 2 D-2 D architecture has been constructed by an easy self-assembly approach and firstly investigated as anode materials for secondary sodium-ion batteries.The SnNb_(2)O_(6)nanosheets are evenly anchored with the aminofunctionalized graphene through electrostatic attractive interplay between the negatively charged SnNb_(2)O_(6)and positively charged En-RGO after modification.As a result,a remarkable reversible capacity of 300 mAh·g^(-1)was obtained at 50 mA·g^(-1),and significantly,the En-RGO electrode could also deliver ultra-long calendar life up to1900 cycles with a high reversible capacity of200 mAh·g^(-1)at current of 500 mA·g^(-1).Such excellent electrochemical characteristics can be mainly ascribed to its fast pseudo-capacitive energy storage mechanism,and the capacitive contribution can even reach up to 90%at1.2 mV·s^(-1). 展开更多
关键词 SnNb2O6 Amino-functionalized graphene Anode material Sodium-ion batteries
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Blockage of the habenular nucleus can eliminate dyspnea induced by electrostimulation of the insular cortex 被引量:3
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作者 mingxian Li Jinghua Wang +4 位作者 min huang Weihong Lin min Wang Lei Yu Shao Wang 《Neural Regeneration Research》 SCIE CAS CSCD 2010年第13期1025-1029,共5页
BACKGROUND: The insular cortex and habenular nucleus may be a regulatory center for obstructive sleep apnea syndrome, and dyspnea may be caused by insular cortex activity. The insular cortex is a cortical representat... BACKGROUND: The insular cortex and habenular nucleus may be a regulatory center for obstructive sleep apnea syndrome, and dyspnea may be caused by insular cortex activity. The insular cortex is a cortical representation of obstructive sleep apnea syndrome. The habenular nucleus is a station for descending insular cortex activity. OBJECTIVE: Through actively stimulating the rat insular cortex, to observe rat respiratory movement, myoelectric activities of genioglossus, arterial partial pressure of oxygen, partial pressure of carbon dioxide and acidity-alkalinity, and to verify a hypothesis that the insular cortex is a superior-position regulation center, and the habenular nucleus is an inferior-position nervous nuclei of the insular cortex in patients with obstructive sleep apnea syndrome. DESIGN, TIME AND SETTING: The randomized, controlled animal study was performed at the Laboratory of Electrophysiology, Department of Physiology, Norman Bathune College of Medicine, Jilin University, China from September 2004 to June 2008. MATERIALS: We used L-glutamic acid (Dingguo Biological Product Research Center, Beijing, China), lidocaine hydrochloride (Seventh Pharmacy Co., Ltd., Wuxi, China), electric stimulator (Nihon Kohden, Japan), and an AVL-OPTI blood gas analyzer (AVL Scientific Co., Roswell, GA, USA). METHODS: The insular cortex of healthy adult Wistar rats underwent electrostimulation and L-glutamic acid stimulation to record changes in the myoelectric activity of genioglossus and respiratory movement. Some rats were injected with lidocaine to block the habenular nucleus before electrostimulation or L-glutamic acid stimulation. L-glutamic acid and lidocaine were injected by microelectrodes embedded in nuclear groups. MAIN OUTCOME MEASURES: Myoelectric activities of genioglossus, arterial partial pressure of oxygen, partial pressure of carbon dioxide and acidity-alkalinity were measured following apnea in rats undergoing electrostimulation in the insular cortex and following blockade of the habenular nucleus. RESULTS: Following electrostimulation and L-glutamic acid stimulation, rats developed apnea or respiratory rhythm disorders. Simultaneously, the amplitude of myoelectric activity of the genioglossus was reduced (P 〈 0.01 ), and the electromyogram integral was decreased (P 〈 0.01). Arterial blood gas analysis showed arterial blood acidosis, a decrease in pH (P 〈 0.05), and an increase in the negative value of alkaline reserve (P 〈 0.01). Lidocaine in the habenular nuclear blocked respiratory and other index changes after insular cortex stimulation. CONCLUSION: Dyspnea induced by stimulating the insular cortex may require the habenular nucleus. Paralysis of the habenular nucleus can completely eliminate insular cortex stimulation-induced dyspnea. 展开更多
关键词 DYSPNEA habenular nucleus insular cortex GENIOGLOSSUS neuroelectrophysiology neural regeneration
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Physiological Processes Contributing to the Difference in Grain Amino Acid Content Between Two Hybrid Rice(Oryza sativa L.)Cultivars 被引量:3
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作者 min huang Hengdong Zhang +2 位作者 Chunrong Zhao Guanghui Chen Yingbin Zou 《Phyton-International Journal of Experimental Botany》 2019年第2期101-107,共7页
Improving grain amino acid content of rice(Oryza sativa L.)is essential for the health of consumers.This study was conducted to identify the physiological processes that contribute to the higher grain amino acid conte... Improving grain amino acid content of rice(Oryza sativa L.)is essential for the health of consumers.This study was conducted to identify the physiological processes that contribute to the higher grain amino acid content in hybrid rice cultivar Lingliangyou 268 compared to Luliangyou 996.The results showed that total amino acid content in grains was 9%higher in Lingliangyou 268 than in Luliangyou 996.There was no significant difference in grain nitrogen(N)content between Lingliangyou 268 and Luliangyou 996,while ratio of amino acid to N was 6%higher in Lingliangyou 268 compared to Luliangyou 996.A total of 16 differentially expressed proteins related to amino acid metabolism(e.g.,erythronate-4-phosphate dehydrogenase domain containing protein)were identified in grains between Lingliangyou 268 and Luliangyou 996.The identified proteins were involved in 10 molecular functions.Six of the 10 defined functions were related to binding(heterocyclic compound binding,nucleoside phosphate binding,nucleotide binding,organic cyclic compound binding,protein binding,and small molecule binding)and the other 4 defined functions were catalytic activity,enzyme regulator activity,hydrolase activity,and transferase activity.These results indicate that the higher grain amino acid content in Lingliangyou 268 compared to Luliangyou 996 is attributed to increased efficiency of converting N to amino acid that results from altered expression of proteins related to amino acid metabolism. 展开更多
关键词 Amino acid content grain quality protein expression protein function hybrid rice
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Role of 5-hydroxytryptamine expression in cerebellar Purkinje cells in obstructive sleep apnea syndrome 被引量:1
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作者 Liping Peng Jinghua Wang +8 位作者 Lihong Zhang Pan Liu min Wang min huang Shengnan Liu Pingping He Li Cui mingxian Li Shao Wang 《Neural Regeneration Research》 SCIE CAS CSCD 2012年第8期606-610,共5页
In the present study, electrical stimulation to the rat insular cortex induced apnea or respiratory disturbance, reduced amplitude of genioglossal electromyogram, and decreased electromyogram integrals. In addition, a... In the present study, electrical stimulation to the rat insular cortex induced apnea or respiratory disturbance, reduced amplitude of genioglossal electromyogram, and decreased electromyogram integrals. In addition, arterial blood gas analysis showed arterial blood acidosis, reduced pH values, increased alkali reserve negative values, decreased peripheral blood 5-hydroxytryptamine content, and increased 5-hydroxytryptamine expression in cerebellar Purkinje cells. Following lidocaine injection to block the habenular nucleus, abnormalities in breath, genioglossal electromyogram, and blood gas values disappeared, and peripheral blood 5-hydroxytryptamine content returned to levels prior to electric stimulation. However, 5-hydroxytryptamine expression in cerebellar Purkinje cells remained high. The results suggested that 5-hydroxytryptamine expression in Purkinje cells did not correlate with ventilation function involving insular cortex and habenular nucleus. 展开更多
关键词 sleep apnea OBSTRUCTIVE CEREBELLUM 5-HYDROXYTRYPTAMINE insular cortex habenular nucleus Purkinje cells
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5-hydroxytryptamine-mediated apnea caused by the habenular nucleus 被引量:1
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作者 min Wang Weihong Lin +4 位作者 Jinghua Wang min huang Chunyong Wang mingxian Li Shao Wang 《Neural Regeneration Research》 SCIE CAS CSCD 2011年第20期1554-1558,共5页
5-hydroxytryptamine contributes to the control of activities of the dilator muscle in the upper respiratory tract, and is derived from the raphe nuclei, in which the habenular nucleus exerts a sustaJned inhibitory eff... 5-hydroxytryptamine contributes to the control of activities of the dilator muscle in the upper respiratory tract, and is derived from the raphe nuclei, in which the habenular nucleus exerts a sustaJned inhibitory effect. In the present study, respiratory motion curve of the genJoglossus muscle and peripheral 5-hydroxytryptamine changes were observed following L-glutamate stimulation of the habenular nucleus of adult Wistar rats. Results showed that the rats had apnea and decreased plasma 5-hydroxytryptamine content after the neurons in habenular nucleus were excited. Genioglossus muscle electromyogram amplitude and integral were significantly reduced. The genioglossus myoelectric activity and respiratory motion curve were similar to obstructive sleep apnea syndrome, thus confirming that the habenular nucleus is the key nucleus involved in the pathogenesis of obstructive sleep apnea syndrome, and is the primary regulated center in the raphe nuclei. Stimulation of the habenular nucleus may suppress 5-hydroxytryptamine release and result in apnea, which is similar to obstructive sleep apnea syndrome. 展开更多
关键词 SLEEP APNEA habenular nucleus 5-HYDROXYTRYPTAMINE GENIOGLOSSUS neural electrophysiology neural regeneration
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Safety evaluation on the clinical application of Tenghuangjiangu tablet for osteoarthritis:a hospital registration study 被引量:2
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作者 min huang 《Traditional Medicine Research》 2017年第1期51-57,共7页
To evaluate the treatment safety of Tenghuangjiangu tablet on osteoarthritis,3365 osteoarthritis patients whose prescription included Tenghuangjiangu tablet from 15 hospitals were involved in the prospective and multi... To evaluate the treatment safety of Tenghuangjiangu tablet on osteoarthritis,3365 osteoarthritis patients whose prescription included Tenghuangjiangu tablet from 15 hospitals were involved in the prospective and multi-center clinical trial.Tenghuangjiangu tablet dosage was decided by instruction or doctors’experience.The course of treatment and observation was 4 weeks.The adverse drug reactions were observed in the treatment process.Results showed male and female patients were 1018(30.25%)and 2347(69.75%),respectively,and 528 patients had allergic history.The patients’average age was 58.30±8.99 years,and the average disease course was 33.29±37.40 months.The average score of WOMAC scale was 95.07±42.42,which indicated the light conditions.2275 patients were treated with combined drug regimen.There were two adverse drug reactions in this research.One reaction was skin rashes with itching and the interventions were stopped original drugs and give antianaphylactic treatment.The other reaction was stomach discomfort with disgusting and the intervention was stopped the original drugs temporarily,then continued to take two drugs after 3 days and the reaction didn’t appear.The accident rate of adverse drug reaction was 0.059%.The safety of Tenghuangjiangu tablet clinical application was good,and the mechanism of adverse drug reaction should be researched in-depth. 展开更多
关键词 Tenghuangjiangu tablet SAFETY OSTEOARTHRITIS
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Phytoremediation of Rare Tailings-Contaminated Soil 被引量:1
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作者 min huang Zhirong Liu Xiang Li 《Journal of Renewable Materials》 SCIE EI 2022年第12期3351-3372,共22页
In order to achieve the goal of circular economy and sustainable development of ecological environment,it is important to separate and recover associated elements from rare mineral resources.Compared with traditional ... In order to achieve the goal of circular economy and sustainable development of ecological environment,it is important to separate and recover associated elements from rare mineral resources.Compared with traditional physical and che-mical remediation methods of contaminated soil,phytoremediation is regarded as the most promising green in-situ restoration technology.The purpose of this review is to efctive alleviate the environmental problems caused by rare tailings contaminated soil through phytoremediation and realize the recovery of uranium-thorium,rare earth elements(REEs)and tantalum niobium.This review took rare tailings with uranium-thorium,REEs tantalum-niobium in China as the research object,then the background,significance,mechanisms and applcation strategies of phytoremediation were elaborated.In additon,the cases of spedies with tolerance to uranium thorium,tantalum niobium as well as REEs and their remediation mechanisms were summarized,respectively.Particularly,the typical plants represented by Bras-sica juncea,Sunflower,Phytolacca americana,Dicramopteris dichotoma,Salix SPP,etc,were very efctive in the reme-diation of rare tailings.The infuence factors of phytoremediation eficiency of tailings contaminated soil were discused.Two main factors were the mobility of heavy metals in soil(external cause)and the ennichment ability of species(inter-nal cause).Since the traditional phytoremediation also had some limitations in view of this,the work discussed some auxiliary methods(such as chelaing agents or microbial assisted restoration)to improve the effiency of phytoreme-diation.Finally,the future development of phytoremediation and potential applcation directions were explored. 展开更多
关键词 Rare tailings uranium-thorium rare earth elements tantalum niobium PHYTOREMEDIATION
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A novel strategy based on the dielectric barrier discharge plasma for rapid elimination of the carryover associated with mPESI-MS/MS system
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作者 Qian Liu Simin Zhang +6 位作者 Xiangyang Qu Yunhui Xing Zhenwei Xiao Shicheng Fan Janshon Zhu min huang Huichang Bi 《Journal of Pharmaceutical Analysis》 CSCD 2024年第11期1714-1716,共3页
In mass spectrometry(MS)analysis,carryover is a common and unavoidable problem.It causes over-estimation of analyte levels,which significantly influences accuracy and precision.Therefore,there are strict limits on car... In mass spectrometry(MS)analysis,carryover is a common and unavoidable problem.It causes over-estimation of analyte levels,which significantly influences accuracy and precision.Therefore,there are strict limits on carryover in MS-based assays.The conventional capillary-based electrospray ionization(ESI)restricts the use of MS for real-time monitoring,where a prompt response is crucial.Recently,we have developed a micro probe electrospray ionization(mPESI)coupled with MS(mPESI-MS)technology,enabling MS analysis within 40 s without a chromatographic column[1].However,the challenge of carryover arises when trying to make the micro probe reusable for resource-saving purposes.Considering that dielectric barrier discharge(DBD)plasma is effective in degrading contaminants in water and gas[2],we hypothesized the eventual use of the DBD plasma to“wash”the micro probe.Then,a DBD plasma wash tube(DBD-WT)was introduced for rapid carryover elimination in mPESI-MS analysis. 展开更多
关键词 ELIMINATION DIELECTRIC sized
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我国抗肿瘤药物研发现状与展望 被引量:3
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作者 黄敏 耿美玉 《中国科学基金》 北大核心 2025年第1期91-98,共8页
基于国家自然科学基金委员会第373期双清论坛“临床问题驱动的肿瘤研究新范式”会议内容,本文总结了我国抗肿瘤药物的研发现状,包括近十年来我国抗肿瘤新药研发取得的显著成果以及当前领域面临的挑战,并在此基础上展望了未来有望催生我... 基于国家自然科学基金委员会第373期双清论坛“临床问题驱动的肿瘤研究新范式”会议内容,本文总结了我国抗肿瘤药物的研发现状,包括近十年来我国抗肿瘤新药研发取得的显著成果以及当前领域面临的挑战,并在此基础上展望了未来有望催生我国抗肿瘤新药研发进一步取得原创突破的着力点和发展方向,以期对我国抗肿瘤药物研究起到指导作用。 展开更多
关键词 抗肿瘤药物 新药研发 分子靶向药物 免疫治疗 精准治疗 抗肿瘤靶点
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Polycystin-1 regulates tendon-derived mesenchymal stem cells fate and matrix organization in heterotopic ossification 被引量:1
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作者 Yi Li Xu Mei huang +8 位作者 Yang Zhang Xin Ying Su min huang Nan Yu Zou Yu Rui Jiao Yu Chen Sun Ling Liu Yong Hua Lei Chang Jun Li 《Bone Research》 2025年第1期183-196,共14页
Mechanical stress modulates bone formation and organization of the extracellular matrix(ECM),the interaction of which affects heterotopic ossification(HO).However,the mechanically sensitive cell populations in HO and ... Mechanical stress modulates bone formation and organization of the extracellular matrix(ECM),the interaction of which affects heterotopic ossification(HO).However,the mechanically sensitive cell populations in HO and the underlying mechanism remain elusive.Here,we show that the mechanical protein Polysyctin-1(PC1,Pkd1)regulates CTSK lineage tendon-derived mesenchymal stem cell(TDMSC)fate and ECM organization,thus affecting HO progression.First,we revealed that CTSK lineage TDMSCs are the major source of osteoblasts and fibroblasts in HO and are responsive to mechanical cues via single-cell RNA sequencing analysis and experiments with a lineage tracing mouse model.Moreover,we showed that PC1 mediates the mechanosignal transduction of CTSK lineage TDMSCs to regulate osteogenic and fibrogenic differentiation and alters the ECM architecture by facilitating TAZ nuclear translocation.Conditional gene depletion of Pkd1 or Taz in CTSK lineage cells and pharmaceutical intervention in the PC1-TAZ axis disrupt osteogenesis,fibrogenesis and ECM organization,and consequently attenuate HO progression.These findings suggest that mechanically sensitive CTSK-lineage TDMSCs contribute to heterotopic ossification through PC1-TAZ signaling axis mediated cell fate determination and ECM organization. 展开更多
关键词 OSSIFICATION HETEROTOPIC TENDON
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ILF3 inhibits p-AMPK expression to drive non-alcoholic fatty liver disease progression
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作者 Ting Zhan Jia-Xi Liu +9 位作者 min huang ming-Tao Chen Xiao-Rong Tian Xiu-Lin Yang Jie Tan Yan-Li Zou Zheng Han Wei Chen Xia Tian Xiao-Dong huang 《World Journal of Hepatology》 2025年第2期170-181,共12页
BACKGROUND Non-alcoholic fatty liver disease(NAFLD)is a disease of increasing global prevalence and an important risk factor for the development of insulin resistance,type 2 diabetes,non-alcoholic steatohepatitis and ... BACKGROUND Non-alcoholic fatty liver disease(NAFLD)is a disease of increasing global prevalence and an important risk factor for the development of insulin resistance,type 2 diabetes,non-alcoholic steatohepatitis and hepatocellular carcinoma,but the pathogenesis is not clear.The aim of this study was to explore the role of ILF3 in NAFLD.AIM To investigate the molecular processes through which ILF3 facilitates the advancement of NAFLD by inhibiting the expression of p-AMPK.This exploration seeks to provide new insights into the etiology of NAFLD and evaluate the potential of ILF3 as a diagnostic marker and potential treatment focus for future interventions.METHODS In vitro and in vivo experiments were conducted using HepG2 cells and NAFLD animal models.The effects of ILF3 knockdown on lipid synthesis and triglyceride(TG)secretion were examined by analyzing the expression levels of p-AMPK.Additionally,the roles of ILF3 and the AMPK signaling pathway were verified using techniques such as Western blotting,quantitative reverse transcription PCR,Oil Red O staining,and immunohistochemistry.RESULTS Investigations revealed an increase in ILF3 Levels within both HepG2 cells and animal models of NAFLD,concurrently with a decrease in p-AMPK expression.Knocking down ILF3 activated the AMPK pathway,reducing lipid production and TG secretion in hepatocytes,thereby mitigating the advancement of NAFLD.CONCLUSION ILF3 promotes the evolution of NAFLD by inhibiting the expression of p-AMPK.The knockdown of ILF3 activates the AMPK signaling pathway,alleviating the severity of NAFLD.These findings underscore the function of ILF3 in the pathogenesis of NAFLD and demonstrate its viability as a treatment focus and diagnostic indicator. 展开更多
关键词 Non-alcoholic fatty liver disease ILF3 AMPK pathway Lipid metabolism Therapeutic target Molecular mechanism
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NSUN2 Promotes Cardiac Hypertrophy by Activating LARP1–GATA4 Axis
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作者 Yingqi Liu Fan Wu +23 位作者 Kuiwu Liu Shuting Yu Changhao Wang Xin Li Zhiyong Sun Wanhong Li Yi Zhang Tiantian Ju Qian Liu min huang Zhongting Mei Zhezhe Qu Meixi Lu Xiaochen Pang Yingqiong Jia Jianhao Jiang Shunkang Dou Na Li Yaozhi Zhang Ying Li Chuanhao huang Yuechao Dong Baofeng Yang Weijie Du 《Engineering》 2025年第8期297-310,共14页
Pathological cardiac hypertrophy contributes to the development of heart failure(HF).NOL1/NOP2/Sun domain family member 2(NSUN2)is implicated in pathophysiological processes of many diseases.However,the function and o... Pathological cardiac hypertrophy contributes to the development of heart failure(HF).NOL1/NOP2/Sun domain family member 2(NSUN2)is implicated in pathophysiological processes of many diseases.However,the function and operation of NSUN2 in cardiac hypertrophy and HF remain unclear.Here,we observed a significant increase in the levels of NSUN2 expression in both human hearts with HF and in mouse hearts with hypertrophy induced by transverse aortic constriction(TAC)and angiotensin II(Ang II)treatment.Cardiomyocyte-specific knockout of NSUN2 attenuated the reduced cardiac ejection fraction(EF)and fractional shortening(FS)and the increased heart weight to tibial length(HW/TL)upon either TAC or Ang II infusion.Conversely,cardiac-specific overexpression of NSUN2 resulted in cardiac remodeling as indicated by a prominent increase in hypertrophic growth and cardiac fibrosis and a robust decline in cardiac EF and FS.Mechanistically,NSUN2 induces 5-methylcytosine(m5C)modification of La-related protein 1(LARP1)to enhance its messenger RNA(mRNA)stability,which is mediated by Y-box binding protein 1(YBX1).Increased LARP1 further interacts with GATA binding protein 4(GATA4)mRNA and prevents its degradation.LARP1 silencing partially attenuates TAC and NSUN2 induced cardiac hypertrophy and HF.Collectively,this study provides a new insight into the central role of NSUN2 in cardiac hypertrophy,indicating that NSUN2 may serve as a novel therapeutic target for HF. 展开更多
关键词 Cardiac hypertrophy 5-Methylcytosine NOL1/NOP2/Sun domain family member 2 Y-box binding protein 1 La-related protein 1 GATA binding protein 4
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The First Scientific Flight and Observations of the 50 mm Balloon-borne White-light Coronagraph
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作者 Kaifeng Kang min huang +13 位作者 Yang Liu Jun Lin Tengfei Song Xuefei Zhang Dayang Liu Tao Zhang Yan Li Jingxing Wang mingzhe Sun mingyu Zhao Guangqian Liu Xianyong Bai Lidong Xia Yu Liu 《Research in Astronomy and Astrophysics》 2025年第12期105-116,共12页
A 50 mm balloon-borne white-light coronagraph(BBWLC)to observe white-light solar corona over the altitude range from 1.08 R_(⊙)to 1.50 R_(⊙)has recently been indigenously developed by Yunnan Observatories in collabo... A 50 mm balloon-borne white-light coronagraph(BBWLC)to observe white-light solar corona over the altitude range from 1.08 R_(⊙)to 1.50 R_(⊙)has recently been indigenously developed by Yunnan Observatories in collaboration with Shandong University(in Weihai)and Changchun Institute of Optics,Fine Mechanics and Physics,which will significantly improve the ability of China to detect and measure the inner corona.On 2022 October 4,its first scientific flight took place at the Dachaidan area in Qinghai province of China.We briefly describe the BBWLC mission including its optical design,mechanical structure,pointing system,the first flight and results associated with the data processing approach.Preliminary analysis of the data shows that BBWLC imaged the K-corona with three streamer structures on the west limb of the Sun.To further confirm the coronal signals obtained by BBWLC,comparisons were made with observations of the K-coronagraph of the High Altitude Observatory and the Atmospheric Imaging Assembly on board the Solar Dynamics Observatory.We conclude that BBWLC eventually observed the white-light corona in its first scientific flight. 展开更多
关键词 Sun:activity Sun:filaments PROMINENCES Sun:coronal mass ejections(CMEs) Sun:flares Sun:magnetic fields
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Grain Photosynthesis and Filling Characteristics of Rice Varieties with Different Grain Weights
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作者 Jinge Li Chuyao Wang +2 位作者 Fangbo Cao min huang Jiana Chen 《Phyton-International Journal of Experimental Botany》 2025年第7期2155-2165,共11页
Grain filling is a critical determinant of yield and quality in rice.This study aims to clarify the association between grain photosynthesis and the filling rate of rice varieties with different grain weights,providin... Grain filling is a critical determinant of yield and quality in rice.This study aims to clarify the association between grain photosynthesis and the filling rate of rice varieties with different grain weights,providing a theoretical foundation for optimizing grain-filling processes.Two rice varieties with similar growth duration but different grain weights were selected:a large-grain variety,Lingliangyou 268(L268),and a small-grain variety,Ruiliangyou 1053(R1053).Differences in grain filling,grain photosynthetic rate,and grain chlorophyll content were systematically examined during the filling stage.Results showed significant differences in grain-filling,grain photosynthetic rate,and grain chlorophyll content between large-grain and small-grain rice varieties.The grain photosynthetic rate of L268 was a significantly higher than R1053.L268 also exhibited significantly higher initial grain filling rate,maximum grainfilling rate,and mean grain filling rate compared to R1053.Throughout the grain filling period,L268 showed higher grain chlorophyll content(including chlorophyll a,chlorophyll b,and total chlorophyll)than R1053.The increase in chlorophyll content,particularly total chlorophyll,enhanced the grain photosynthetic rate during the early and middle stages of grain filling significantly.These findings suggested that rice varieties with higher grain weights exhibited stronger panicle photosynthetic capacity due to their higher chlorophyll content.The enhanced grain photosynthetic rate contributed to improved grain filling and increased grain weight. 展开更多
关键词 Grain chlorophyll content grain filling grain weight photosynthetic capacity panicle photosynthesis rice panicle
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TGICP:A Text-Gated Interaction Network with Inter-Sample Commonality Perception for Multimodal Sentiment Analysis
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作者 Erlin Tian Shuai Zhao +3 位作者 min huang Yushan Pan Yihong Wang Zuhe Li 《Computers, Materials & Continua》 2025年第10期1427-1456,共30页
With the increasing importance of multimodal data in emotional expression on social media,mainstream methods for sentiment analysis have shifted from unimodal to multimodal approaches.However,the challenges of extract... With the increasing importance of multimodal data in emotional expression on social media,mainstream methods for sentiment analysis have shifted from unimodal to multimodal approaches.However,the challenges of extracting high-quality emotional features and achieving effective interaction between different modalities remain two major obstacles in multimodal sentiment analysis.To address these challenges,this paper proposes a Text-Gated Interaction Network with Inter-Sample Commonality Perception(TGICP).Specifically,we utilize a Inter-sample Commonality Perception(ICP)module to extract common features from similar samples within the same modality,and use these common features to enhance the original features of each modality,thereby obtaining a richer and more complete multimodal sentiment representation.Subsequently,in the cross-modal interaction stage,we design a Text-Gated Interaction(TGI)module,which is text-driven.By calculating the mutual information difference between the text modality and nonverbal modalities,the TGI module dynamically adjusts the influence of emotional information from the text modality on nonverbal modalities.This helps to reduce modality information asymmetry while enabling full cross-modal interaction.Experimental results show that the proposed model achieves outstanding performance on both the CMU-MOSI and CMU-MOSEI baseline multimodal sentiment analysis datasets,validating its effectiveness in emotion recognition tasks. 展开更多
关键词 Multi-modal sentiment analysis multi-modal fusion graph convolutional networks inter-sample commonality perception gated interaction
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Adherence to dietary guidelines and nutritional awareness among a population of Chinese university students:comparative analysis across sex,ethnicity,and BMI groups
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作者 Da Pan Dilinigeer Nuerxiati +18 位作者 Chenxin Shi Xiaoran Meng Yang Suo Yong Zhang Yuanyuan Wang Wei Xie min huang Wen Xu Jawhar Mamatjan Adila Abuduwupur Yajie Zhou Yanli Gao Shiyun Wan Ligang Yang Baofu Guo Shaokang Wang Guiju Sun Hui Xia Di Jin 《Food Science and Human Wellness》 2025年第11期4682-4692,共11页
University students,transitioning from adolescence to adulthood,are at a critical stage where dietary habits and health behaviors are established,influencing long-term health outcomes.This study aimed to assess the di... University students,transitioning from adolescence to adulthood,are at a critical stage where dietary habits and health behaviors are established,influencing long-term health outcomes.This study aimed to assess the dietary intake and nutritional awareness of a population of Chinese university students(n=833),comparing their consumption with national dietary guidelines and reference intakes,while exploring subgroup differences.Results indicated that males had significantly higher amounts of most food categories compared to females.Except for whole grains and legumes,ethnic minorities had lower compliance with the recommended intakes for several food categories compared to Han Chinese.Han males consumed more energy,protein,and fat than their ethnic minority counterparts.Obese participants showed higher protein and fat intake compared to those with normal body mass index(BMI).Additionally,BMI-related trends in macronutrient contributions showed that protein and fat contributed more to the total energy intake of individuals with higher BMI.Han individuals also had higher energy contributions from protein and fat and lower carbohydrate contributions compared to ethnic minorities.Nutrient intake was generally below recommended levels,with low proportions of participants meeting the recommended intake for vitamin A,C,calcium and dietary fiber.High proportions of participants exceeded the tolerable upper intake levels for iron and manganese.Nutritional awareness scores were also significantly higher among Han students,as well as those with higher BMIs and higher income levels.This study highlights significant disparities in dietary intake and nutritional awareness among Chinese university students,with variations across sex,ethnicity,BMI,and income categories. 展开更多
关键词 Chinese university students Dietary intake Nutritional awareness Chinese Dietary Guidelines Dietary reference intakes(DRIs)
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One new sap beetle species of Pocadius Erichson(Coleoptera:Nitidulidae:Nitidulinae)
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作者 Huan ZHANG Xiaoxiao CHEN +1 位作者 Josef JELÍNEK min huang 《Entomotaxonomia》 2025年第1期26-29,共4页
One new species,Pocadius spiralis sp.nov.,is described and illustrated from Sichuan,China.
关键词 POLYPHAGA Nitiduloidea morphology TAXONOMY
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New genera,species and records of the microleafhopper tribe Alebrini(Hemiptera:Cicadellidae:Typhlocybinae)from south China
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作者 Yixiao LUO Juxia KANG +1 位作者 Yalin ZHANG min huang 《Entomotaxonomia》 2025年第2期113-122,共10页
We report a genus with 2 species newly from China and describe 2 new genera and 3 new species of the tribe Alebrini(Hemiptera:Cicadellidae:Typhlocybinae)to science:the newly-recorded genus Orientalebra Dworakowska rec... We report a genus with 2 species newly from China and describe 2 new genera and 3 new species of the tribe Alebrini(Hemiptera:Cicadellidae:Typhlocybinae)to science:the newly-recorded genus Orientalebra Dworakowska rec.nov.with 2 new records species,O.gembata Dworakowska rec.nov.and O.drawidana Dworakowska rec.nov.,and a new species,O.brevicolumnaria Kang&Zhang sp.nov.;the new genus Brachyblastus Kang&Zhang gen.nov.with its type species B.rhombeus Kang&Zhang sp.nov.and the new genus Pedalobulus Kang&Zhang gen.nov.with its type species P.quinquegeminatus Kang&Zhang sp.nov.Detailed morphological illustrations and a key to males of new taxa are provided. 展开更多
关键词 AUCHENORRHYNCHA Membracoidea taxonomy
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