Objectives: To examine the cross-sectional associations of the separate subscales of the Perceived Stress Scale (PSS) and tests measuring cognitive domains in older adults. Methods: 897 adults over the age of 70 free ...Objectives: To examine the cross-sectional associations of the separate subscales of the Perceived Stress Scale (PSS) and tests measuring cognitive domains in older adults. Methods: 897 adults over the age of 70 free of amnestic mild cognitive impairment and dementia and enrolled in the Einstein Aging Study made up the study sample. The PSS-14 was used to measure stress. Three cognitive domains (language, episodic memory, and frontal-executive) had previously been found using principle component analysis. Linear regression analyses were used to determine the relationship between the PSS subscales and cognitive domain function. Results: The study sample had a mean age of 79.1 years and 62.8% were female. Bivariate correlations show that the PSS-14 positively worded subscale of the PSS (PSS-PW) was significantly associated with all three cognitive domains (language: r = -0.15, p < 0.001;episodic memory: r = -0.16, p < 0.001;frontal-executive: r = -0.21, p <0.001) while the negatively worded subscale of the PSS (PSS-NW) was not significantly associated with any cognitive domain. In linear regression analyses adjusted for age, white race, gender, years of education, and depressive symptoms, the PSS-PW remained significantly associated with each of the cognitive domains. The PSS-NW was not associated with any cognitive domains in any model. The PSS-14 was significantly associated with language and episodic memory, but not the frontal-executive domain. Conclusion: Worse PSS-PW scores are associated with reduced cognitive function in the executive, memory, and language domains in nondemented older adults. The PSS-PW subscale correlated better with cognitive function than the overall PSS-14. Future research should evaluate the temporality of the association and if stress reduction therapies improve cognitive performance.展开更多
Dose modest alcohol consumption(MAC)help the health care?There is a mainstream that MAC may not aggravate or even reduce cardiovascular disease and all-cause mortality(1,2).Light(≤3 drink/week)or moderate(>3 to≤1...Dose modest alcohol consumption(MAC)help the health care?There is a mainstream that MAC may not aggravate or even reduce cardiovascular disease and all-cause mortality(1,2).Light(≤3 drink/week)or moderate(>3 to≤14 drinks/week for men or>3 to≤7 drinks/week for women)alcohol consumption were reducing risk of mortality for all causes and cardiovascular disease(2).In 2018,combined analysis of 599,912 current drinkers in 83 prospective studies of high income countries,showed alcohol consumption was positive and curvilinear association with all-cause mortality and roughly linearly associated with a cardiovascular disease other than myocardial infarction(1).They recommend the threshold for lowest risk of all-cause mortality was 100 g/week.展开更多
文摘Objectives: To examine the cross-sectional associations of the separate subscales of the Perceived Stress Scale (PSS) and tests measuring cognitive domains in older adults. Methods: 897 adults over the age of 70 free of amnestic mild cognitive impairment and dementia and enrolled in the Einstein Aging Study made up the study sample. The PSS-14 was used to measure stress. Three cognitive domains (language, episodic memory, and frontal-executive) had previously been found using principle component analysis. Linear regression analyses were used to determine the relationship between the PSS subscales and cognitive domain function. Results: The study sample had a mean age of 79.1 years and 62.8% were female. Bivariate correlations show that the PSS-14 positively worded subscale of the PSS (PSS-PW) was significantly associated with all three cognitive domains (language: r = -0.15, p < 0.001;episodic memory: r = -0.16, p < 0.001;frontal-executive: r = -0.21, p <0.001) while the negatively worded subscale of the PSS (PSS-NW) was not significantly associated with any cognitive domain. In linear regression analyses adjusted for age, white race, gender, years of education, and depressive symptoms, the PSS-PW remained significantly associated with each of the cognitive domains. The PSS-NW was not associated with any cognitive domains in any model. The PSS-14 was significantly associated with language and episodic memory, but not the frontal-executive domain. Conclusion: Worse PSS-PW scores are associated with reduced cognitive function in the executive, memory, and language domains in nondemented older adults. The PSS-PW subscale correlated better with cognitive function than the overall PSS-14. Future research should evaluate the temporality of the association and if stress reduction therapies improve cognitive performance.
文摘Dose modest alcohol consumption(MAC)help the health care?There is a mainstream that MAC may not aggravate or even reduce cardiovascular disease and all-cause mortality(1,2).Light(≤3 drink/week)or moderate(>3 to≤14 drinks/week for men or>3 to≤7 drinks/week for women)alcohol consumption were reducing risk of mortality for all causes and cardiovascular disease(2).In 2018,combined analysis of 599,912 current drinkers in 83 prospective studies of high income countries,showed alcohol consumption was positive and curvilinear association with all-cause mortality and roughly linearly associated with a cardiovascular disease other than myocardial infarction(1).They recommend the threshold for lowest risk of all-cause mortality was 100 g/week.
