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Electrocardiograms changes in children with functional gastrointestinal disorders on low dose amitriptyline
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作者 Ashish Chogle miguel saps 《World Journal of Gastroenterology》 SCIE CAS 2014年第32期11321-11325,共5页
AIM: To study the effects of low dose amitriptyline on cardiac conduction in children.
关键词 AMITRIPTYLINE ELECTROCARDIOGRAM CHILDREN Abdominal pain related-functional gastrointestinal disorders
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X-ray detection of ingested non-metallic foreign bodies
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作者 miguel saps John M Rosen Jacob Ecanow 《World Journal of Clinical Pediatrics》 2014年第2期14-18,共5页
AIM: To determine the utility of X-ray in identifying non-metallic foreign body(FB) and assess inter-radiologist agreement in identifying non-metal FB. METHODS: Focus groups of nurses, fellows, and attending physician... AIM: To determine the utility of X-ray in identifying non-metallic foreign body(FB) and assess inter-radiologist agreement in identifying non-metal FB. METHODS: Focus groups of nurses, fellows, and attending physicians were conducted to determine commonly ingested objects suitable for inclusion. Twelve potentially ingested objects(clay, plastic bead, crayon, plastic ring, plastic army figure, glass bead, paperclip, drywall anchor, eraser, Lego?, plastic triangle toy, and barrette) were embedded in a gelatin slab placed on top of a water-equivalent phantom to simulate density of a child's abdomen. The items were selected due to wide availability and appropriate size for accidental pediatric ingestion. Plain radiography of the embedded FBs was obtained. Five experienced radiologists blinded to number and types of objects were asked to identify the FBs. The radiologist was first asked to count thenumber of items that were visible then to identify the shape of each item and describe it to a study investigator who recorded all responses. Overall inter-rater reliability was analyzed using percent agreement and κ coefficient. We calculated P value to assess the probability of error involved in accepting the κ value.RESULTS: Fourteen objects were radiographed including 12 original objects and 2 duplicates. The model's validity was supported by clear identification of a radiolucent paperclip as a positive control, and lack of identification of plastic beads(negative control) despite repeated inclusion. Each radiologist identified 7-9 of the 14 objects(mean 8, 67%). Six unique objects(50%) were identified by all radiologists and four unique objects(33%) were not identified by any radiologist(plastic bead, LegoTM, plastic triangle toy, and barrette). Identification of objects that were not present, false-positives, occurred 1-2 times per radiologist(mean 1.4). An additional 17% of unique objects were identified by less than half of the radiologists. Agreement between radiologists was considered almost perfect(kappa 0.86 ± 0.08, P < 0.0001).CONCLUSION: We demonstrate potential non-identification of commonly ingested non-metal FBs in children. A registry for radiographic visibility of ingested objects should be created to improve clinical decision-making. 展开更多
关键词 FOREIGN BODIES X-rays PEDIATRICS RADIOGRAPHIC PHANTOM DIAGNOSTIC imaging
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儿童功能性胃肠病罗马Ⅳ标准 被引量:148
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作者 Marc A.Benninga Samuel Nurko +14 位作者 Christophe Faure Paul E.Hyman Ian St.James Roberts Neil L.Schechter Jeffrey S.Hyams Carlo Di Lorenzo miguel saps Robert J.Shulman Annamaria Staiano Miranda van Tilburg 耿岚岚(译) 刘明南 龙高 龚四堂(审校) 江米足 《中华儿科杂志》 CAS CSCD 北大核心 2017年第1期4-14,共11页
罗马标准是目前关于功能性胃肠病(FGID)分类最全面且不断更新的标准。罗马Ⅰ、Ⅱ标准分别于1994年、1999年发布。罗马Ⅱ标准开始单列儿童FGID分类。2006年,根据年龄不同,婴幼儿(0~36个月)和儿童(>36个月)FGID的罗马Ⅲ诊断标准发布,... 罗马标准是目前关于功能性胃肠病(FGID)分类最全面且不断更新的标准。罗马Ⅰ、Ⅱ标准分别于1994年、1999年发布。罗马Ⅱ标准开始单列儿童FGID分类。2006年,根据年龄不同,婴幼儿(0~36个月)和儿童(>36个月)FGID的罗马Ⅲ诊断标准发布,但相关的流行病学、病理生理学、诊断检查、治疗策略以及预后等资料都很少。过去10年,不同年龄儿童各种FGID的研究已经有了新的进展。FGID罗马专家委员会对相关的诊断标准进行了修订,并于2016年正式在Gastroenterology上发表儿童FGID罗马Ⅳ标准,其中新生儿、婴幼儿部分Benninga MA和Nurko S为并列第一作者,儿童、青少年部分Hyams JS和Lorenzo CD为并列第一作者。既往诊断FGID要先排除器质性病变的观念已得到更新,目前诊断主要基于以症状为基础的循证依据。在儿童、青少年罗马Ⅳ诊断标准中,已删除“没有器质性疾病的证据”的条件,而代之以“经过适当的医疗评估,患儿的症状不能归因于其他的疾病”。这种变化允许临床医生可有选择性地进行或不必进行临床检验也能诊断FGID。婴儿肠绞痛分为临床诊断标准和临床研究标准,功能性恶心和功能性呕吐已被分开描述。罗马Ⅲ诊断标准中的“腹痛相关的功能性胃肠病”被改称为“功能性腹痛疾病”,对不符合肠易激综合征、功能性消化不良或腹型偏头痛等疾病诊断标准的功能性腹痛疾病统称为“非特异性功能性腹痛”。现就儿童罗马Ⅳ诊断标准主要内容进行介绍和解读。 展开更多
关键词 功能性胃肠病 罗马标准 儿童 FGID 罗马Ⅱ标准 病理生理学 诊断标准 流行病学
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