Using the determinant quantum Monte Carlo method,we explore a rich phase diagram featuring strain-induced metal-insulator and magnetic phase transitions in an interacting two-dimensional Dirac fermion system.Asymmetri...Using the determinant quantum Monte Carlo method,we explore a rich phase diagram featuring strain-induced metal-insulator and magnetic phase transitions in an interacting two-dimensional Dirac fermion system.Asymmetric strain applied along the zigzag crystal direction drives the semimetallic regime into a band-insulating phase,or it breaks the antiferromagnetic order of the Mott insulator,inducing a nonmagnetic insulating phase under strong correlations.The critical strain required for band gap opening or for a transport phase transition is significantly reduced in the presence of Coulomb repulsion,while increasing interaction strength makes it more difficult for strain to induce a nonmagnetic phase transition.In addition,we measure in detail the band gap modulation by strain and identify a doping effect whereby doping inhibits band gap opening.Our results provide an effective way to tune the transport gap,which could help extend the applications of graphene,whose zero band gap currently limits its use.展开更多
目的探讨阿托伐他汀对高血压脑出血(hypertensive intracerebral hemorrhage,HCH)患者白介素-33(IL-33)水平的影响。方法80例HCH患者随机平分为对照组、观察组,对照组用常规方法治疗,观察组用常规方法联合口服阿托伐他汀治疗。疗程结束...目的探讨阿托伐他汀对高血压脑出血(hypertensive intracerebral hemorrhage,HCH)患者白介素-33(IL-33)水平的影响。方法80例HCH患者随机平分为对照组、观察组,对照组用常规方法治疗,观察组用常规方法联合口服阿托伐他汀治疗。疗程结束时对比两组总有效率、脑水肿绝对体积和相对体积、美国国立卫生院卒中量表(national institutes of health stroke scale,NIHSS)、格拉斯哥昏迷指数(glasgow coma index,GCS)评分,神经元特异性烯醇化酶(neuron specific enolase,NSE)、中枢神经特异蛋白(central nervous system specific protein,S100β)、白介素-33(interleukin-33,IL-33)、白介素-1β(interleukin-1β,IL-1β)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)和C反应蛋白(C-reactive protein,CRP)水平。结果治疗后,观察组总有效率95%高于对照组78%(χ^(2)=5.168,P<0.05)。治疗前两组脑水肿的绝对、相对体积接近,对比差异无统计学意义(t=0.181、0.797,P>0.05);治疗后两组脑水肿的绝对、相对体积均低于治疗前(t=15.323、15.034、24.425、13.038,P<0.05),治疗后观察组脑水肿的绝对、相对体积均少于对照组(t=3.171、13.265,P<0.05)。治疗前两组NIHSS、GCS评分对比差异无统计学意义(t=0.778、0.967,P>0.05);治疗后两组NIHSS评分低于治疗前,GCS评分高于治疗前(t=27.370、23.857、7.101、4.443,P<0.05);治疗后观察组NIHSS评分少于对照组,GCS评分高于对照组(t=7.247、2.713,P<0.05)。治疗前两组NSE、S100β水平对比无统计学差异(t=0.425、0.349,P>0.05);治疗后两组NSE、S100β水平低于治疗前(t=6.065、4.436、20.109、7.030,P<0.05);治疗后观察组NSE、S100β水平少于对照组(t=2.278、12.818,P<0.05)。治疗前两组IL-33、IL-1β、TNF-α和CRP水平对比无统计学差异(t=0.043、1.265、0.708、0.157,P>0.05);治疗后两组IL-33、IL-1β、TNF-α和CRP水平低于治疗前(t=5.120、2.119、11.610、4.207、8.378、3.604、7.552、5.420,P<0.05);治疗后观察组IL-33、IL-1β、TNF-α和CRP水平少于对照组(t=3.703、3.336、2.389、5.087,P<0.05)。两组不良反应发生率对比,差异无统计学意义(χ^(2)=0.312,P>0.05)。结论阿托伐他汀治疗HCH患者疗效显著,显著促进水肿的吸收,减缓功能缺损,缓解意识障碍,降低NSE、S100β炎症因子水平,提高IL-33水平。展开更多
Background:Although fear of cancer recurrence(FCR)is the most important factor affecting the life quality of young breast cancer patients,and it may be affected by the patient’s personality,marital relationship and c...Background:Although fear of cancer recurrence(FCR)is the most important factor affecting the life quality of young breast cancer patients,and it may be affected by the patient’s personality,marital relationship and communication,there is a lack of research on the relationship between adult attachment,self-disclosure and FCR in patients.This study investigated the current situation of FCR in young breast cancer patients,its correlation with adult attachment and self-disclosure and its influencing factors,in order to predict the impact of adult attachment and self-disclosure of patients to spouse on FCR.Methods:A survey was conducted on 126 breast cancer patients at our hospital using the General Information Questionnaire(GIQ),Fear of Progression Questionnaire-Short Form(FoP-Q-SF),Experiences in Close Relationships inventory(ECR),and Distress Disclosure Index(DDI).The study analyzed the status of FCR among young breast cancer patients and its correlation with adult attachment and self-disclosure,along with its influencing factors.Results:Among the 126 young breast cancer patients,50 had a FoP-Q-SF score<34(normal group),while 76 had a FoP-Q-SF score≥34(FCR positive group),with an FCR incidence rate of 60.32%.Univariate analysis showed statistically significant differences between the two groups in terms of FoP-Q-SF score,ECR score,attachment anxiety score,attachment avoidance score,DDI score,age,educational level,employment status,per capita monthly income,and treatment method(p<0.05).Correlation analysis revealed that FoP-Q-SF scores were positively correlated with attachment anxiety score,attachment avoidance score,ECR scores and negatively correlated with DDI scores(p<0.05).Linear regression analysis indicated that age,per capita monthly income,treatment method,attachment anxiety,attachment avoidance and self-disclosure level were negative predictors of FoP-Q-SF scores in young breast cancer patients(p<0.05).Conclusion:The incidence rate of FCR among young breast cancer patients is high.There is a positive correlation between adult attachment and the level of FCR,and a negative correlation between the level of self-disclosure and FCR.Patients with lower per capita monthly income,more complex treatment methods,higher level of attachment anxiety,higher level of attachment avoidance and lower DDI scores had higher FoP-Q-SF scores.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.12474218)the Beijing Natural Science Foundation(Grant No.1242022)the Guangxi Key Laboratory of Precision Navigation Technology and Application,Guilin University of Electronic Technology(Grant No.DH202322)。
文摘Using the determinant quantum Monte Carlo method,we explore a rich phase diagram featuring strain-induced metal-insulator and magnetic phase transitions in an interacting two-dimensional Dirac fermion system.Asymmetric strain applied along the zigzag crystal direction drives the semimetallic regime into a band-insulating phase,or it breaks the antiferromagnetic order of the Mott insulator,inducing a nonmagnetic insulating phase under strong correlations.The critical strain required for band gap opening or for a transport phase transition is significantly reduced in the presence of Coulomb repulsion,while increasing interaction strength makes it more difficult for strain to induce a nonmagnetic phase transition.In addition,we measure in detail the band gap modulation by strain and identify a doping effect whereby doping inhibits band gap opening.Our results provide an effective way to tune the transport gap,which could help extend the applications of graphene,whose zero band gap currently limits its use.
文摘目的探讨阿托伐他汀对高血压脑出血(hypertensive intracerebral hemorrhage,HCH)患者白介素-33(IL-33)水平的影响。方法80例HCH患者随机平分为对照组、观察组,对照组用常规方法治疗,观察组用常规方法联合口服阿托伐他汀治疗。疗程结束时对比两组总有效率、脑水肿绝对体积和相对体积、美国国立卫生院卒中量表(national institutes of health stroke scale,NIHSS)、格拉斯哥昏迷指数(glasgow coma index,GCS)评分,神经元特异性烯醇化酶(neuron specific enolase,NSE)、中枢神经特异蛋白(central nervous system specific protein,S100β)、白介素-33(interleukin-33,IL-33)、白介素-1β(interleukin-1β,IL-1β)、肿瘤坏死因子-α(tumor necrosis factor-α,TNF-α)和C反应蛋白(C-reactive protein,CRP)水平。结果治疗后,观察组总有效率95%高于对照组78%(χ^(2)=5.168,P<0.05)。治疗前两组脑水肿的绝对、相对体积接近,对比差异无统计学意义(t=0.181、0.797,P>0.05);治疗后两组脑水肿的绝对、相对体积均低于治疗前(t=15.323、15.034、24.425、13.038,P<0.05),治疗后观察组脑水肿的绝对、相对体积均少于对照组(t=3.171、13.265,P<0.05)。治疗前两组NIHSS、GCS评分对比差异无统计学意义(t=0.778、0.967,P>0.05);治疗后两组NIHSS评分低于治疗前,GCS评分高于治疗前(t=27.370、23.857、7.101、4.443,P<0.05);治疗后观察组NIHSS评分少于对照组,GCS评分高于对照组(t=7.247、2.713,P<0.05)。治疗前两组NSE、S100β水平对比无统计学差异(t=0.425、0.349,P>0.05);治疗后两组NSE、S100β水平低于治疗前(t=6.065、4.436、20.109、7.030,P<0.05);治疗后观察组NSE、S100β水平少于对照组(t=2.278、12.818,P<0.05)。治疗前两组IL-33、IL-1β、TNF-α和CRP水平对比无统计学差异(t=0.043、1.265、0.708、0.157,P>0.05);治疗后两组IL-33、IL-1β、TNF-α和CRP水平低于治疗前(t=5.120、2.119、11.610、4.207、8.378、3.604、7.552、5.420,P<0.05);治疗后观察组IL-33、IL-1β、TNF-α和CRP水平少于对照组(t=3.703、3.336、2.389、5.087,P<0.05)。两组不良反应发生率对比,差异无统计学意义(χ^(2)=0.312,P>0.05)。结论阿托伐他汀治疗HCH患者疗效显著,显著促进水肿的吸收,减缓功能缺损,缓解意识障碍,降低NSE、S100β炎症因子水平,提高IL-33水平。
文摘Background:Although fear of cancer recurrence(FCR)is the most important factor affecting the life quality of young breast cancer patients,and it may be affected by the patient’s personality,marital relationship and communication,there is a lack of research on the relationship between adult attachment,self-disclosure and FCR in patients.This study investigated the current situation of FCR in young breast cancer patients,its correlation with adult attachment and self-disclosure and its influencing factors,in order to predict the impact of adult attachment and self-disclosure of patients to spouse on FCR.Methods:A survey was conducted on 126 breast cancer patients at our hospital using the General Information Questionnaire(GIQ),Fear of Progression Questionnaire-Short Form(FoP-Q-SF),Experiences in Close Relationships inventory(ECR),and Distress Disclosure Index(DDI).The study analyzed the status of FCR among young breast cancer patients and its correlation with adult attachment and self-disclosure,along with its influencing factors.Results:Among the 126 young breast cancer patients,50 had a FoP-Q-SF score<34(normal group),while 76 had a FoP-Q-SF score≥34(FCR positive group),with an FCR incidence rate of 60.32%.Univariate analysis showed statistically significant differences between the two groups in terms of FoP-Q-SF score,ECR score,attachment anxiety score,attachment avoidance score,DDI score,age,educational level,employment status,per capita monthly income,and treatment method(p<0.05).Correlation analysis revealed that FoP-Q-SF scores were positively correlated with attachment anxiety score,attachment avoidance score,ECR scores and negatively correlated with DDI scores(p<0.05).Linear regression analysis indicated that age,per capita monthly income,treatment method,attachment anxiety,attachment avoidance and self-disclosure level were negative predictors of FoP-Q-SF scores in young breast cancer patients(p<0.05).Conclusion:The incidence rate of FCR among young breast cancer patients is high.There is a positive correlation between adult attachment and the level of FCR,and a negative correlation between the level of self-disclosure and FCR.Patients with lower per capita monthly income,more complex treatment methods,higher level of attachment anxiety,higher level of attachment avoidance and lower DDI scores had higher FoP-Q-SF scores.
