Background:“Yang Transforming Qi and Yin shaping”comes from“Plain Question Yin and Yang should be like the theory”.Chinese medicine believes that the imbalance of yin and yang is the cause of human diseases.One of...Background:“Yang Transforming Qi and Yin shaping”comes from“Plain Question Yin and Yang should be like the theory”.Chinese medicine believes that the imbalance of yin and yang is the cause of human diseases.One of the strengths of TCM in treating diseases is holistic regulation.The theory of“Yang transforming Qi,and Yin shaping”implies a strong holistic view.Chloasma,one of the common skin diseases,seriously affects the physical and mental health of patients due to its unclear etiology,difficult treatment and easy recurrence.The occurrence and development of chloasma are closely related to internal organs.This paper is based on the theory of internal meridian,“Yang transforming Qi,and Yin shaping”which attaches importance to the concept of“Yang Qi”,from a new understanding of the pathogenesis etiology of chloasma.Methods:The author believes that the incidence of the disease is the deficiency of Yang Qi,which can’t promote the movement of Qi and blood to nourish the face,resulting in tangible material condensation,so proposes that this disease needs to be promoted by Yang transforming Qi and warm to dissipate.Moxibustion belongs to the fire,and its warming effect can dissipate the tangible evil.Results:Combined with clinical practice and the theory of internal meridian,the author elaborated that moxibustion is one of the effective methods for treating chloasma,which provides a new way of thinking for the treatment of chloasma.Conclusion:“Yang Transforming Qi and Yin shaping”can be used to guide the treatment of chloasma.展开更多
针对多能源虚拟电厂(multi-energy virtual power plant,MEVPP)在可再生能源高渗透率下面临的源荷多重不确定性挑战,提出一种日前-实时两阶段风险规避随机优化经济调度模型,通过集成碳捕集、利用与封存-电转气系统来提升可再生能源消纳...针对多能源虚拟电厂(multi-energy virtual power plant,MEVPP)在可再生能源高渗透率下面临的源荷多重不确定性挑战,提出一种日前-实时两阶段风险规避随机优化经济调度模型,通过集成碳捕集、利用与封存-电转气系统来提升可再生能源消纳能力与碳减排效益。首先,将Copula函数与瓦瑟坦距离相结合,选取最优Copula函数并构建风光联合出力典型场景集;其次,设计两阶段随机优化调度模型,第一阶段以运行成本最小化为目标制定调度方案,第二阶段针对实时不确定性以平衡成本最小化为目标,通过备用调用、综合需求响应及储能协同平抑波动,重新调整调度计划;最后,结合条件风险价值理论量化风光出力和负荷等多重不确定性的风险成本,并采用Gurobi求解器对MEVPP优化模型进行求解。对MEVPP风险经济优化模型进行了仿真验证,结果表明,所设计策略在优化设备出力的同时,实现了风光100%全消纳,显著提升了调度方案的可执行性与风险适应性。展开更多
Wireless channel characteristics have significant impacts on channel modeling,estimation,and communication performance.While the channel sparsity is an important characteristic of wireless channels.Utilizing the spars...Wireless channel characteristics have significant impacts on channel modeling,estimation,and communication performance.While the channel sparsity is an important characteristic of wireless channels.Utilizing the sparse nature of wireless channels can reduce the complexity of channel modeling and estimation,and improve system design and performance analysis.Compared with the traditional sub6 GHz channel,millimeter wave(mmWave)channel has been considered to be more sparse in existing researches.However,most research only assume that the mmWave channel is sparse,without providing quantitative analysis and evaluation.Therefore,this paper evaluates the sparsity of mmWave channels based on mmWave channel measurements.A vector network analyzer(VNA)-based mmWave channel sounder is developed to measure the channel at 28 GHz,and multi-scenario channel measurements are conducted.The Gini index,Rician𝐾factor and rootmean-square(RMS)delay spread are used to measure channel sparsity.Then,the key factors affecting mmWave channel sparsity are explored.It is found that antenna steering direction and scattering environment will affect the sparsity of mmWave channel.In addition,the impact of channel sparsity on channel eigenvalue and capacity is evaluated and analyzed.展开更多
In this paper,a massive multiple input multiple output(MIMO)channel measurement campaign with two setups is conducted in an indoor lobby environment.In the first setup,two types of 256-element virtual uniform rectangu...In this paper,a massive multiple input multiple output(MIMO)channel measurement campaign with two setups is conducted in an indoor lobby environment.In the first setup,two types of 256-element virtual uniform rectangular arrays(URAs),i.e.,the 4×64 virtual URA and the 64×4 virtual URA are used.The carrier frequency is 11 GHz;in the second setup,measurements are performed at 4,6,11,13,15,18 GHz at two different user locations.The channel characterization is presented by investigating the typical channel parameters,including average power delay profile(APDP),K factor,root mean square(RMS)delay spread,and coherence bandwidth.Moreover,the channel characteristics in angular domain are investigated by applying the space-alternating generalized expectation-maximization(SAGE)algorithm.The extracted multipath components(MPCs)are preliminarily clustered by visual inspection,and related to the interacting objects(IOs)in physical environment.Multipath structures at multiple frequency bands are examined.Direction spread of departure is estimated to evaluate the directional dispersion at the base station(BS)side.The results in this paper can help to reveal the propagation mechanisms in massive MIMO channels,and provide a foundation for the design and application of the practical massive MIMO system.展开更多
Marine geological disasters occurred frequently in the deep-water slope area of the northern South China Sea,especially submarine landslides,which caused serious damage to marine facilities.The cyclic elastoplastic mo...Marine geological disasters occurred frequently in the deep-water slope area of the northern South China Sea,especially submarine landslides,which caused serious damage to marine facilities.The cyclic elastoplastic model that can describe the cyclic stress-strain response characteristic for soft clay,is embedded into the coupled Eulerian-Lagrangian(CEL)algorithm of ABAQUS by means of subroutine interface technology.On the basis of CEL technique and undrained cyclic elastoplastic model,a method for analyzing the dynamic instability process of marine slopes under the action of earthquake load is developed.The rationality for cyclic elastoplastic constitutive model is validated by comparing its calculated results with those of von Mises model built in Abaqus.The dynamic instability process of slopes under different conditions are analyzed.The results indicate that the deformation accumulation of soft clay have a significant effect on the dynamic instability process of submarine slopes under earthquake loading.The cumulative deformation is taken into our model and this makes the calculated final deformation of the slope under earthquake load larger than the results of conventional numerical method.When different contact conditions are used for analysis,the smaller the friction coefficient is,the larger the deformation of slopes will be.A numerical analysis method that can both reflect the dynamic properties of soft clay and display the dynamic instability process of submarine landslide is proposed,which could visually predict the topographies of the previous and post failure for submarine slope.展开更多
BACKGROUND Nonketotic hyperglycemia(NKH)is characterized by hyperglycemia with little or no ketoacidosis.Diverse neurological symptoms have been described in NKH patients,including choreoathetosis,hemiballismus,seizur...BACKGROUND Nonketotic hyperglycemia(NKH)is characterized by hyperglycemia with little or no ketoacidosis.Diverse neurological symptoms have been described in NKH patients,including choreoathetosis,hemiballismus,seizures,and coma in severe cases.Homonymous hemianopia,with or without occipital seizures,caused by hyperglycemia is less readily recognized.CASE SUMMARY We describe a 54-year-old man with NKH,who reported seeing round,colored flickering lights with right homonymous hemianopia.Cranial magnetic resonance imaging demonstrated abnormalities in the left occipital lobe,with decreased T2 signal of the white matter,restricted diffusion,and corresponding low signal intensity in the apparent diffusion coefficient map.He responded to rehydration and a low-dose insulin regimen,with improvements of his visual field defect.CONCLUSION Patients with NKH may present focal neurologic signs.Hyperglycemia should be taken into consideration when making an etiologic diagnosis of homonymous hemianopia.展开更多
BACKGROUND Congenital muscular dystrophy(CMD)is a clinically and genetically heterogeneous group of inherited muscle disorders.Mutations in the CRPPA gene(encoding CDPLribitol pyrophosphorylase A)are recognized as cau...BACKGROUND Congenital muscular dystrophy(CMD)is a clinically and genetically heterogeneous group of inherited muscle disorders.Mutations in the CRPPA gene(encoding CDPLribitol pyrophosphorylase A)are recognized as causative factors of dystroglycanopathies,a subtype of CMD with defects in glycosylation.CASE SUMMARY The present study examined a Chinese family,whose proband presented mainly with muscle weakness in both lower limbs but without brain and eye symptoms.In this family,a homozygous deletion,c.1114-1116del(p.V372del),was identified in exon 8 of CRPPA in the proband,while a heterozygous deletion was identified in the proband’s father and mother,who lacked symptoms.A mild dystroglycanopathy of CMD was diagnosed.CONCLUSION The findings of this study expanded the clinical and mutational spectrum of patients with CMD associated with CRPPA mutations.展开更多
基金Project of TCM&Combination of Traditional Chinese and Western Medicine of Tianjin Health(Commission:2021003,2021004).
文摘Background:“Yang Transforming Qi and Yin shaping”comes from“Plain Question Yin and Yang should be like the theory”.Chinese medicine believes that the imbalance of yin and yang is the cause of human diseases.One of the strengths of TCM in treating diseases is holistic regulation.The theory of“Yang transforming Qi,and Yin shaping”implies a strong holistic view.Chloasma,one of the common skin diseases,seriously affects the physical and mental health of patients due to its unclear etiology,difficult treatment and easy recurrence.The occurrence and development of chloasma are closely related to internal organs.This paper is based on the theory of internal meridian,“Yang transforming Qi,and Yin shaping”which attaches importance to the concept of“Yang Qi”,from a new understanding of the pathogenesis etiology of chloasma.Methods:The author believes that the incidence of the disease is the deficiency of Yang Qi,which can’t promote the movement of Qi and blood to nourish the face,resulting in tangible material condensation,so proposes that this disease needs to be promoted by Yang transforming Qi and warm to dissipate.Moxibustion belongs to the fire,and its warming effect can dissipate the tangible evil.Results:Combined with clinical practice and the theory of internal meridian,the author elaborated that moxibustion is one of the effective methods for treating chloasma,which provides a new way of thinking for the treatment of chloasma.Conclusion:“Yang Transforming Qi and Yin shaping”can be used to guide the treatment of chloasma.
文摘针对多能源虚拟电厂(multi-energy virtual power plant,MEVPP)在可再生能源高渗透率下面临的源荷多重不确定性挑战,提出一种日前-实时两阶段风险规避随机优化经济调度模型,通过集成碳捕集、利用与封存-电转气系统来提升可再生能源消纳能力与碳减排效益。首先,将Copula函数与瓦瑟坦距离相结合,选取最优Copula函数并构建风光联合出力典型场景集;其次,设计两阶段随机优化调度模型,第一阶段以运行成本最小化为目标制定调度方案,第二阶段针对实时不确定性以平衡成本最小化为目标,通过备用调用、综合需求响应及储能协同平抑波动,重新调整调度计划;最后,结合条件风险价值理论量化风光出力和负荷等多重不确定性的风险成本,并采用Gurobi求解器对MEVPP优化模型进行求解。对MEVPP风险经济优化模型进行了仿真验证,结果表明,所设计策略在优化设备出力的同时,实现了风光100%全消纳,显著提升了调度方案的可执行性与风险适应性。
基金supported by National Key R&D Program of China under Grant 2022YFF0608103the National Natural Science Foundation of China under Grant 61922012+1 种基金the Science and Technology Program of State Administration for Market Regulation under Grant 2021MK155the Fundamental Funds of National Institute of Metrology under Grant AKYZD2116-2.
文摘Wireless channel characteristics have significant impacts on channel modeling,estimation,and communication performance.While the channel sparsity is an important characteristic of wireless channels.Utilizing the sparse nature of wireless channels can reduce the complexity of channel modeling and estimation,and improve system design and performance analysis.Compared with the traditional sub6 GHz channel,millimeter wave(mmWave)channel has been considered to be more sparse in existing researches.However,most research only assume that the mmWave channel is sparse,without providing quantitative analysis and evaluation.Therefore,this paper evaluates the sparsity of mmWave channels based on mmWave channel measurements.A vector network analyzer(VNA)-based mmWave channel sounder is developed to measure the channel at 28 GHz,and multi-scenario channel measurements are conducted.The Gini index,Rician𝐾factor and rootmean-square(RMS)delay spread are used to measure channel sparsity.Then,the key factors affecting mmWave channel sparsity are explored.It is found that antenna steering direction and scattering environment will affect the sparsity of mmWave channel.In addition,the impact of channel sparsity on channel eigenvalue and capacity is evaluated and analyzed.
基金supported in part by the National Key Research and Development Program of China under Grant 2016YFE0200900 and 2018YFF0212103in part by NSFC under Grant 61725101, 61771037, 6181101396, and U1834210+4 种基金in part by the Beijing Natural Science Foundation under Grant 4182047 and L172020in part by the Fundamental research funds for the central universities under Grant 2017RC031 and Grant 2018JBM301in part by the Major projects of Beijing Municipal Science and Technology Commission under Grant Z181100003218010in part by the State Key Lab of Rail Traffic Control and Safety under Grant 2017JBM332, RCS2018ZZ007, and Grant RCS2018ZT014in part by the Teaching Reform Project under Grant 134496522
文摘In this paper,a massive multiple input multiple output(MIMO)channel measurement campaign with two setups is conducted in an indoor lobby environment.In the first setup,two types of 256-element virtual uniform rectangular arrays(URAs),i.e.,the 4×64 virtual URA and the 64×4 virtual URA are used.The carrier frequency is 11 GHz;in the second setup,measurements are performed at 4,6,11,13,15,18 GHz at two different user locations.The channel characterization is presented by investigating the typical channel parameters,including average power delay profile(APDP),K factor,root mean square(RMS)delay spread,and coherence bandwidth.Moreover,the channel characteristics in angular domain are investigated by applying the space-alternating generalized expectation-maximization(SAGE)algorithm.The extracted multipath components(MPCs)are preliminarily clustered by visual inspection,and related to the interacting objects(IOs)in physical environment.Multipath structures at multiple frequency bands are examined.Direction spread of departure is estimated to evaluate the directional dispersion at the base station(BS)side.The results in this paper can help to reveal the propagation mechanisms in massive MIMO channels,and provide a foundation for the design and application of the practical massive MIMO system.
基金This work was supported by the National Natural Science Foundation of China(NSFC)(No.51179174).
文摘Marine geological disasters occurred frequently in the deep-water slope area of the northern South China Sea,especially submarine landslides,which caused serious damage to marine facilities.The cyclic elastoplastic model that can describe the cyclic stress-strain response characteristic for soft clay,is embedded into the coupled Eulerian-Lagrangian(CEL)algorithm of ABAQUS by means of subroutine interface technology.On the basis of CEL technique and undrained cyclic elastoplastic model,a method for analyzing the dynamic instability process of marine slopes under the action of earthquake load is developed.The rationality for cyclic elastoplastic constitutive model is validated by comparing its calculated results with those of von Mises model built in Abaqus.The dynamic instability process of slopes under different conditions are analyzed.The results indicate that the deformation accumulation of soft clay have a significant effect on the dynamic instability process of submarine slopes under earthquake loading.The cumulative deformation is taken into our model and this makes the calculated final deformation of the slope under earthquake load larger than the results of conventional numerical method.When different contact conditions are used for analysis,the smaller the friction coefficient is,the larger the deformation of slopes will be.A numerical analysis method that can both reflect the dynamic properties of soft clay and display the dynamic instability process of submarine landslide is proposed,which could visually predict the topographies of the previous and post failure for submarine slope.
基金The fund of Department of Education Zhejiang Province Scientific Research Project,No.Y201839721Zhejiang Province Medical Science and Technology Project,No.2017174708,No.2020RC061,and No.2018273034+2 种基金the Zhejiang Provincial Natural Scientific Foundation of China,No.LGF20H090011 and No.LY18H090002Zhejiang public welfare Technology Application Research Project,No.LGF20H090011the Medical and Health Science and Technology Program of Zhejiang Province,No.2018273034.
文摘BACKGROUND Nonketotic hyperglycemia(NKH)is characterized by hyperglycemia with little or no ketoacidosis.Diverse neurological symptoms have been described in NKH patients,including choreoathetosis,hemiballismus,seizures,and coma in severe cases.Homonymous hemianopia,with or without occipital seizures,caused by hyperglycemia is less readily recognized.CASE SUMMARY We describe a 54-year-old man with NKH,who reported seeing round,colored flickering lights with right homonymous hemianopia.Cranial magnetic resonance imaging demonstrated abnormalities in the left occipital lobe,with decreased T2 signal of the white matter,restricted diffusion,and corresponding low signal intensity in the apparent diffusion coefficient map.He responded to rehydration and a low-dose insulin regimen,with improvements of his visual field defect.CONCLUSION Patients with NKH may present focal neurologic signs.Hyperglycemia should be taken into consideration when making an etiologic diagnosis of homonymous hemianopia.
基金the Medical and Health Science and Technology Program of Zhejiang Province,No.2018273034.
文摘BACKGROUND Congenital muscular dystrophy(CMD)is a clinically and genetically heterogeneous group of inherited muscle disorders.Mutations in the CRPPA gene(encoding CDPLribitol pyrophosphorylase A)are recognized as causative factors of dystroglycanopathies,a subtype of CMD with defects in glycosylation.CASE SUMMARY The present study examined a Chinese family,whose proband presented mainly with muscle weakness in both lower limbs but without brain and eye symptoms.In this family,a homozygous deletion,c.1114-1116del(p.V372del),was identified in exon 8 of CRPPA in the proband,while a heterozygous deletion was identified in the proband’s father and mother,who lacked symptoms.A mild dystroglycanopathy of CMD was diagnosed.CONCLUSION The findings of this study expanded the clinical and mutational spectrum of patients with CMD associated with CRPPA mutations.
