This case reports a 63-year-old male patient who was admitted to the hospital due to the discovery of sigmoid colon protrusion during physical examination.EUS indicated submucosal lesions,and lymphangioma was initiall...This case reports a 63-year-old male patient who was admitted to the hospital due to the discovery of sigmoid colon protrusion during physical examination.EUS indicated submucosal lesions,and lymphangioma was initially considered.Colonoscopy revealed a 0-Is+Ⅱc type protrusion,with a smooth surface and visible dendritic vessels.The biopsy was tough.Auxiliary imaging showed no distant metastasis or obvious organ damage,and the laboratory test results were normal.The pathological confirmation after submucosal dissection was non-Hodgkin's small B-cell lymphoma(MALT lymphoma).Combining imaging,pathological and immunohistochemical analyses,this case emphasizes the precise sampling and classification strategy for submucosal masses in the digestive tract,suggesting that endoscopic biopsy is difficult to fully reflect submucosal infiltration and should be supplemented by EUS and large tissue sampling.In terms of treatment,based on the local lesion,pathological classification and the patient's overall condition,a strategy combining endoscopic dissection and subsequent chemotherapy is selected to achieve a balance between local control and systemic intervention.展开更多
文摘This case reports a 63-year-old male patient who was admitted to the hospital due to the discovery of sigmoid colon protrusion during physical examination.EUS indicated submucosal lesions,and lymphangioma was initially considered.Colonoscopy revealed a 0-Is+Ⅱc type protrusion,with a smooth surface and visible dendritic vessels.The biopsy was tough.Auxiliary imaging showed no distant metastasis or obvious organ damage,and the laboratory test results were normal.The pathological confirmation after submucosal dissection was non-Hodgkin's small B-cell lymphoma(MALT lymphoma).Combining imaging,pathological and immunohistochemical analyses,this case emphasizes the precise sampling and classification strategy for submucosal masses in the digestive tract,suggesting that endoscopic biopsy is difficult to fully reflect submucosal infiltration and should be supplemented by EUS and large tissue sampling.In terms of treatment,based on the local lesion,pathological classification and the patient's overall condition,a strategy combining endoscopic dissection and subsequent chemotherapy is selected to achieve a balance between local control and systemic intervention.