Vitamin C (ascorbic acid) plays an important role in maintaining skin health, and topical vitamin C supplementation can counteract oxidative stress induced by UVA, due to excellent reducibility. To clarify the efficac...Vitamin C (ascorbic acid) plays an important role in maintaining skin health, and topical vitamin C supplementation can counteract oxidative stress induced by UVA, due to excellent reducibility. To clarify the efficacy of vitamin C on the skin in the carrier of lotion, we studied its permeability, irritation and anti-aging effect in vitro and in vivo, using Franz cell system, cell model and clinical test. The permeability test showed that vitamin C with 10%, 15%, 20% and 25% mass ratio could effectively penetrate skin. The 20% of vitamin C lotion (VCL-20%) had the highest efficiency of transdermal penetration and the diffusion percentage reached 84.707% after 24 h. Besides, the permeation quantity of VCL-20% was 1.43 times that of the control group. Irritation test showed that the cytotoxicity of vitamin C lotion was low. And no allergic reaction happened in the occlusive patch test. Compared with the control group, using vitamin C lotion for 28 days could significantly improve subjects’ skin gloss of 10.53% and improve skin color, enhance facial skin elasticity and tightness of 9.20% and reduce wrinkle area of 12.27% (p < 0.05).展开更多
In this paper, we introduce 3-Horn-Lie bialgebras whose compatibility conditions between the multiplication and comultiplication are given by local cocycle conditions. We study a twisted 3-ary version of the Yang-Baxt...In this paper, we introduce 3-Horn-Lie bialgebras whose compatibility conditions between the multiplication and comultiplication are given by local cocycle conditions. We study a twisted 3-ary version of the Yang-Baxter Equation, called the 3-Lie classical Hom- Yang-Baxter Equation （3-Lie CHYBE）, which is a general form of 3-Lie classical Yang-Baxter Equation and prove that the bialgebras induced by the solutions of 3-Lie CHYBE induce the coboundary local cocycle 3-Horn-Lie bialgebras.展开更多
文摘Vitamin C (ascorbic acid) plays an important role in maintaining skin health, and topical vitamin C supplementation can counteract oxidative stress induced by UVA, due to excellent reducibility. To clarify the efficacy of vitamin C on the skin in the carrier of lotion, we studied its permeability, irritation and anti-aging effect in vitro and in vivo, using Franz cell system, cell model and clinical test. The permeability test showed that vitamin C with 10%, 15%, 20% and 25% mass ratio could effectively penetrate skin. The 20% of vitamin C lotion (VCL-20%) had the highest efficiency of transdermal penetration and the diffusion percentage reached 84.707% after 24 h. Besides, the permeation quantity of VCL-20% was 1.43 times that of the control group. Irritation test showed that the cytotoxicity of vitamin C lotion was low. And no allergic reaction happened in the occlusive patch test. Compared with the control group, using vitamin C lotion for 28 days could significantly improve subjects’ skin gloss of 10.53% and improve skin color, enhance facial skin elasticity and tightness of 9.20% and reduce wrinkle area of 12.27% (p < 0.05).
基金Supported by the National Natural Science Foundation of China(Grant No.11047030)the Science and Technology Program of Henan Province(Grant No.152300410061)
文摘In this paper, we introduce 3-Horn-Lie bialgebras whose compatibility conditions between the multiplication and comultiplication are given by local cocycle conditions. We study a twisted 3-ary version of the Yang-Baxter Equation, called the 3-Lie classical Hom- Yang-Baxter Equation （3-Lie CHYBE）, which is a general form of 3-Lie classical Yang-Baxter Equation and prove that the bialgebras induced by the solutions of 3-Lie CHYBE induce the coboundary local cocycle 3-Horn-Lie bialgebras.
