A new efficient synthesis of bisphenol A diether bis-imidazoles and bis-benzimidazoles by bromoalkylation and imidazolylation or benzimidazolylation two-step reactions from commercial bisphenol A,imidazole,2-methylimi...A new efficient synthesis of bisphenol A diether bis-imidazoles and bis-benzimidazoles by bromoalkylation and imidazolylation or benzimidazolylation two-step reactions from commercial bisphenol A,imidazole,2-methylimidazole and benzimidazole is reported.展开更多
The repeat unit of Candida kefyr IFO 0586 strain was designed,and a protected pentasaccharide was synthesized by thirteen-step reactions.Trichloroacetoxy was used as leaving group at anomeric carbon.
A facile and efficient synthesis for a series of bis(N-imidazolylethyl)ethers from oligo-ethyleneglycols and imidazole has been studied.All these compounds obtained were characterized by MS,(HNMR)-H-1,and elemental an...A facile and efficient synthesis for a series of bis(N-imidazolylethyl)ethers from oligo-ethyleneglycols and imidazole has been studied.All these compounds obtained were characterized by MS,(HNMR)-H-1,and elemental analysis.展开更多
the acetate of a novel phenolic glycoside,1-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyloxy-3-hydroxy-5-methylbenzene anacardoside,from the fruits of Semecarpus anacardium,and its diastereomer were first s...the acetate of a novel phenolic glycoside,1-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyloxy-3-hydroxy-5-methylbenzene anacardoside,from the fruits of Semecarpus anacardium,and its diastereomer were first synthesized using Koenigs-Knorr method from D-glucose through six steps with total yields 33%and 16%respectively.展开更多
The condensation reaction between 5-amino-4, 6-dichloro-2-methylpyrimidine and 1-acetyl-2-imidazolin-2-one using POCl3 as solvent gave 4, 6-dichloro-2-methyl-5-(1-acetyl-tetra- hydro-imidazo-2-ylidene)-aminopyrimidine...The condensation reaction between 5-amino-4, 6-dichloro-2-methylpyrimidine and 1-acetyl-2-imidazolin-2-one using POCl3 as solvent gave 4, 6-dichloro-2-methyl-5-(1-acetyl-tetra- hydro-imidazo-2-ylidene)-aminopyrimidine predominantly and 4, 6-dichloro-2-methyl-5-{1-[1-(2- oxo-tetrahydro-imidazolyl)]-acetyene}-aminopyrimidine as by-product. No 4, 6-dichloro-2- methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyrimidine was found. The result indicated an esterifi- cation-addition-elimination mechanism.展开更多
In the presence of BF3.OEt2, 1-O-trimethylsilyi-2,3,4,6-tetra-O-benzyl-α-D-mannopyranose (1)reacted stereoselectively with a series of carboxylic acids to give the corresponding α-mannosyl carboxylates in good yield...In the presence of BF3.OEt2, 1-O-trimethylsilyi-2,3,4,6-tetra-O-benzyl-α-D-mannopyranose (1)reacted stereoselectively with a series of carboxylic acids to give the corresponding α-mannosyl carboxylates in good yields. The configuration of products was assigned mainly by 1H-NMR spectra (δH1 and 2J1.2).展开更多
基金the China Postdoctoral Science Foundationthe Special Funds of StateEducational Committee for Doctorate Scientific Researchthe National Natural ScienceFoundation of China.
文摘A new efficient synthesis of bisphenol A diether bis-imidazoles and bis-benzimidazoles by bromoalkylation and imidazolylation or benzimidazolylation two-step reactions from commercial bisphenol A,imidazole,2-methylimidazole and benzimidazole is reported.
基金financial support from the Union Laboratory of Asysmmetric SynthesisChengdu Institute of Organic Chemistry,Academia Sinicathe China Postdoctoral Science Foundation.
文摘The repeat unit of Candida kefyr IFO 0586 strain was designed,and a protected pentasaccharide was synthesized by thirteen-step reactions.Trichloroacetoxy was used as leaving group at anomeric carbon.
基金the China Postdoctoral Science Foundationthe Special Funds of State Educational Committee for Doctorate Scientific Researchthe National Natural ScienceFoundation of China.
文摘A facile and efficient synthesis for a series of bis(N-imidazolylethyl)ethers from oligo-ethyleneglycols and imidazole has been studied.All these compounds obtained were characterized by MS,(HNMR)-H-1,and elemental analysis.
基金supported by the Scientific Research Foundation for Returned Overseas Chinese Scholars,State Education Commission,China.
文摘the acetate of a novel phenolic glycoside,1-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyloxy-3-hydroxy-5-methylbenzene anacardoside,from the fruits of Semecarpus anacardium,and its diastereomer were first synthesized using Koenigs-Knorr method from D-glucose through six steps with total yields 33%and 16%respectively.
文摘The condensation reaction between 5-amino-4, 6-dichloro-2-methylpyrimidine and 1-acetyl-2-imidazolin-2-one using POCl3 as solvent gave 4, 6-dichloro-2-methyl-5-(1-acetyl-tetra- hydro-imidazo-2-ylidene)-aminopyrimidine predominantly and 4, 6-dichloro-2-methyl-5-{1-[1-(2- oxo-tetrahydro-imidazolyl)]-acetyene}-aminopyrimidine as by-product. No 4, 6-dichloro-2- methyl-5-(1-acetyl-2-imidazolin-2-yl)-aminopyrimidine was found. The result indicated an esterifi- cation-addition-elimination mechanism.
文摘In the presence of BF3.OEt2, 1-O-trimethylsilyi-2,3,4,6-tetra-O-benzyl-α-D-mannopyranose (1)reacted stereoselectively with a series of carboxylic acids to give the corresponding α-mannosyl carboxylates in good yields. The configuration of products was assigned mainly by 1H-NMR spectra (δH1 and 2J1.2).
