Tissue-resident type 2 innate lymphoid cells(ILC2s)help orchestrate local inflammation.As early responding cells to danger signals and tissue damage,they produce key cytokines that directly influence the breadth and d...Tissue-resident type 2 innate lymphoid cells(ILC2s)help orchestrate local inflammation.As early responding cells to danger signals and tissue damage,they produce key cytokines that directly influence the breadth and depth of the immune response,including surveillance during tumor development and progression.Like T cells,ILC2s express immune checkpoint molecules on their surface that regulate their effector function.In lung cancer,Ciancaglini et al.展开更多
文摘Tissue-resident type 2 innate lymphoid cells(ILC2s)help orchestrate local inflammation.As early responding cells to danger signals and tissue damage,they produce key cytokines that directly influence the breadth and depth of the immune response,including surveillance during tumor development and progression.Like T cells,ILC2s express immune checkpoint molecules on their surface that regulate their effector function.In lung cancer,Ciancaglini et al.