Orthostatic hypertension(OHT)is a condition characterized by an increase in blood pressure after assuming the standing position.[1]Nowadays no consensus definition exists,thus OHT prevalence varies among studies(4%-20...Orthostatic hypertension(OHT)is a condition characterized by an increase in blood pressure after assuming the standing position.[1]Nowadays no consensus definition exists,thus OHT prevalence varies among studies(4%-20.3%).展开更多
Orthostatic hypotension (OH)is a common condition in older persons.According to the 2011criteria,OH is defined by a sustained reduction of systolic blood pressure of 20 mmHg or a 10mmHg-fall of diastolic blood pressur...Orthostatic hypotension (OH)is a common condition in older persons.According to the 2011criteria,OH is defined by a sustained reduction of systolic blood pressure of 20 mmHg or a 10mmHg-fall of diastolic blood pressure,[1] Its prevalence increases with age and according to a recent systematic review the pooled prevalence in community dwelling older people is 22.2%.[2]Although OH is largely explained by concurrent clinical conditions (in particular, hypertension,diabetes,malnutrition,vascular encephalopa- thy,anemia,Parkinson's disease)[3],aging per se determines a series of physiological dysfunctions potentially representing its biological substratum (e.g.,reduction in barore- flex-mediated cardiovascular function,altered salt and water balance at renal level,impaired cardiac diastolic filling).It is also noteworthy that age-related changes in pharmacokinetic and pharmacodynamic mechanisms of drugs (especially in the context of polypharmacy)also increase the risk of OH.展开更多
INTRODUCTION The United Nations(UN)Decade of Healthy Ageing(2021–2030),coordinated by the World Health Organization(WHO),1 is a global collaborative initiative aimed at improving the lives of older people,their famil...INTRODUCTION The United Nations(UN)Decade of Healthy Ageing(2021–2030),coordinated by the World Health Organization(WHO),1 is a global collaborative initiative aimed at improving the lives of older people,their families and the communities.23 The Action Areas 3(ie,‘deliver person-centred,integrated care and primary health services responsive to older people’)and 4(ie,‘provide access to long-term care(LTC)for older people who need it’)of the Decade’s work programme focus on reorienting health and care systems to promote‘ageing in place’and the delivery of personalised interventions in a seamless continuum of care.展开更多
Objective Several research gaps affect the improvement of care for healthy ageing.Their identification is crucial to developing a specific research prioritisation agenda supporting progress at the micro(clinical),meso...Objective Several research gaps affect the improvement of care for healthy ageing.Their identification is crucial to developing a specific research prioritisation agenda supporting progress at the micro(clinical),meso(service delivery)and macro(system)levels.To achieve this,a scoping review was carried out to describe the most significant gaps impeding the improvement of care for healthy ageing.Design A scoping review of the literature was conducted according to the Joanna Briggs Institute methodology.The selected articles were analysed to identify topics or areas essential for improving care for healthy ageing but requiring further support from research.Eligibility criteria Every type of scientific article,except for randomised controlled trials,was considered of potential interest without restrictions on publication date,type of publication and methodology.Information sources A systematic search(last search:6 December 2023)was conducted using PubMed,MEDLINE and Scopus.Results Overall,1558 articles were retrieved from the literature.Of these,310 were finally retained for this work.A total of 1195 research gaps were identified(average:3.85 per article)and clustered into the 13 primary areas:ageing,care approach,caregivers,health economics,health,interventions,policies,research,settings,training,technology,specific populations and understanding the older person.In particular,research for improving the person-centred approach(n=38),better considering cultural diversities(n=27),implementing integrated care(n=25)and ensuring access to care(n=25)were the most prevalent priorities reported in the literature.Conclusions A wide range of factors spanning multiple disciplines,from clinical to policy levels,require special consideration,exploration and resolution.The findings of this scoping review represent an essential step in identifying gaps for developing a research prioritisation agenda to improve care for healthy ageing.展开更多
文摘Orthostatic hypertension(OHT)is a condition characterized by an increase in blood pressure after assuming the standing position.[1]Nowadays no consensus definition exists,thus OHT prevalence varies among studies(4%-20.3%).
文摘Orthostatic hypotension (OH)is a common condition in older persons.According to the 2011criteria,OH is defined by a sustained reduction of systolic blood pressure of 20 mmHg or a 10mmHg-fall of diastolic blood pressure,[1] Its prevalence increases with age and according to a recent systematic review the pooled prevalence in community dwelling older people is 22.2%.[2]Although OH is largely explained by concurrent clinical conditions (in particular, hypertension,diabetes,malnutrition,vascular encephalopa- thy,anemia,Parkinson's disease)[3],aging per se determines a series of physiological dysfunctions potentially representing its biological substratum (e.g.,reduction in barore- flex-mediated cardiovascular function,altered salt and water balance at renal level,impaired cardiac diastolic filling).It is also noteworthy that age-related changes in pharmacokinetic and pharmacodynamic mechanisms of drugs (especially in the context of polypharmacy)also increase the risk of OH.
文摘INTRODUCTION The United Nations(UN)Decade of Healthy Ageing(2021–2030),coordinated by the World Health Organization(WHO),1 is a global collaborative initiative aimed at improving the lives of older people,their families and the communities.23 The Action Areas 3(ie,‘deliver person-centred,integrated care and primary health services responsive to older people’)and 4(ie,‘provide access to long-term care(LTC)for older people who need it’)of the Decade’s work programme focus on reorienting health and care systems to promote‘ageing in place’and the delivery of personalised interventions in a seamless continuum of care.
文摘Objective Several research gaps affect the improvement of care for healthy ageing.Their identification is crucial to developing a specific research prioritisation agenda supporting progress at the micro(clinical),meso(service delivery)and macro(system)levels.To achieve this,a scoping review was carried out to describe the most significant gaps impeding the improvement of care for healthy ageing.Design A scoping review of the literature was conducted according to the Joanna Briggs Institute methodology.The selected articles were analysed to identify topics or areas essential for improving care for healthy ageing but requiring further support from research.Eligibility criteria Every type of scientific article,except for randomised controlled trials,was considered of potential interest without restrictions on publication date,type of publication and methodology.Information sources A systematic search(last search:6 December 2023)was conducted using PubMed,MEDLINE and Scopus.Results Overall,1558 articles were retrieved from the literature.Of these,310 were finally retained for this work.A total of 1195 research gaps were identified(average:3.85 per article)and clustered into the 13 primary areas:ageing,care approach,caregivers,health economics,health,interventions,policies,research,settings,training,technology,specific populations and understanding the older person.In particular,research for improving the person-centred approach(n=38),better considering cultural diversities(n=27),implementing integrated care(n=25)and ensuring access to care(n=25)were the most prevalent priorities reported in the literature.Conclusions A wide range of factors spanning multiple disciplines,from clinical to policy levels,require special consideration,exploration and resolution.The findings of this scoping review represent an essential step in identifying gaps for developing a research prioritisation agenda to improve care for healthy ageing.
