Photonic integrated circuits(PICs)represent a promising technology for the muchneeded medical devices of today.Their primary advantage lies in their ability to integrate multiple functions onto a single chip,thereby r...Photonic integrated circuits(PICs)represent a promising technology for the muchneeded medical devices of today.Their primary advantage lies in their ability to integrate multiple functions onto a single chip,thereby reducing the complexity,size,maintenance requirements,and costs.When applied to optical coherence tomography(OCT),the leading tool for state-of-the-art ophthalmic diagnosis,PICs have the potential to increase accessibility,especially in scenarios,where size,weight,or costs are limiting factors.In this paper,we present a PIC-based CMOS-compatible spectrometer for spectral domain OCT with an unprecedented level of integration.To achieve this,we co-integrated a 512-channel arrayed waveguide grating with electronics.We successfully addressed the challenge of establishing a connection from the optical waveguides to the photodiodes monolithically co-integrated on the chip with minimal losses achieving a coupling efficiency of 70%.With this fully integrated PIC-based spectrometer interfaced to a spectral domain OCT system,we reached a sensitivity of 92dB at an imaging speed of 55kHz,with a 6dB signal roll-off occurring at 2mm.We successfully applied this innovative technology to obtain 3D in vivo tomograms of zebrafish larvae and human skin.This ground-breaking fully integrated spectrometer represents a significant step towards a miniaturised,cost-effective,and maintenance-free OCT system.展开更多
基金carried out in the framework of the project COHESION,No.848588funded by the Austrian Research Promotion Agency(FFG)support for the research of this work from funding from the European Union’s Horizon 2020 research and innovation program HandheldOCT(H2020,ICT 871312).
文摘Photonic integrated circuits(PICs)represent a promising technology for the muchneeded medical devices of today.Their primary advantage lies in their ability to integrate multiple functions onto a single chip,thereby reducing the complexity,size,maintenance requirements,and costs.When applied to optical coherence tomography(OCT),the leading tool for state-of-the-art ophthalmic diagnosis,PICs have the potential to increase accessibility,especially in scenarios,where size,weight,or costs are limiting factors.In this paper,we present a PIC-based CMOS-compatible spectrometer for spectral domain OCT with an unprecedented level of integration.To achieve this,we co-integrated a 512-channel arrayed waveguide grating with electronics.We successfully addressed the challenge of establishing a connection from the optical waveguides to the photodiodes monolithically co-integrated on the chip with minimal losses achieving a coupling efficiency of 70%.With this fully integrated PIC-based spectrometer interfaced to a spectral domain OCT system,we reached a sensitivity of 92dB at an imaging speed of 55kHz,with a 6dB signal roll-off occurring at 2mm.We successfully applied this innovative technology to obtain 3D in vivo tomograms of zebrafish larvae and human skin.This ground-breaking fully integrated spectrometer represents a significant step towards a miniaturised,cost-effective,and maintenance-free OCT system.
