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中国人群孕前队列研究先兆子痫:原理、研究方法和基线结果(英文) 被引量:3
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作者 文师吾 谭红专 +2 位作者 谢日华 Graeme N. Smith mark walker 《中南大学学报(医学版)》 CAS CSCD 北大核心 2012年第11期1081-1087,共7页
目的:目前尚不清楚先兆子痫是由孕前因素还是妊娠因素所引起。本研究通过在中国湖南地区建立孕前队列以阐明先兆子痫的病因。方法:本研究拟在湖南浏阳地区招募5000对半年内有怀孕打算的未孕夫妇,并追踪研究对象的怀孕、分娩及产后情况... 目的:目前尚不清楚先兆子痫是由孕前因素还是妊娠因素所引起。本研究通过在中国湖南地区建立孕前队列以阐明先兆子痫的病因。方法:本研究拟在湖南浏阳地区招募5000对半年内有怀孕打算的未孕夫妇,并追踪研究对象的怀孕、分娩及产后情况。结果:目前本孕前队列共招募了1915对未孕夫妇。与孕前相比较,产妇的收缩压和舒张压在孕中早期有所下降,然而在孕后期有所上升。结论:孕前队列的建立将对孕期先兆子痫及产后心血管疾病的预防发挥重要的理论和实际意义。 展开更多
关键词 孕前队列 先兆子痫 中国
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1995至2002年美国产妇试产及与试产相关的新生儿患病率和病死率趋势(英文) 被引量:2
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作者 文师吾 郭燕芳 +2 位作者 谢日华 Jessica Dy mark walker 《中南大学学报(医学版)》 CAS CSCD 北大核心 2012年第11期1088-1096,共9页
目的:目前剖宫产后未经试产的重复剖宫产率不断上升。本研究拟探讨美国产妇试产率的下降与新生儿出生结局之间的关系。方法:采用1995至2002年间美国出生登记资料进行分析。选取既往剖宫产术分娩过一次单胎的产妇作为研究对象。通过多元l... 目的:目前剖宫产后未经试产的重复剖宫产率不断上升。本研究拟探讨美国产妇试产率的下降与新生儿出生结局之间的关系。方法:采用1995至2002年间美国出生登记资料进行分析。选取既往剖宫产术分娩过一次单胎的产妇作为研究对象。通过多元logistic回归估算试产率高和低的两个时段中,新生儿不良出生结局与试产之间的调整OR值。结果:本研究共选取了1833407名研究对象。美国既往剖宫产产妇再次分娩时的试产率从1995年的38.5%降低至2002年的15.0%。在此期间产妇的基线资料没有发生具有统计学意义的改变。既往剖宫产产妇再次分娩时未经试产会增加新生儿发生窒息死亡和患病的风险。通过分析试产率最低的2002年的数据,发现该风险在低危产妇中仍然存在。结论:美国产妇剖宫产后再次分娩时试产率下降导致了新生儿不良结局的发生率上升。 展开更多
关键词 试产 选择性剖宫产 长期趋势 新生儿病死率 新生儿患病率
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Association between change of health care providers and pregnancy exposure to FDA category C, D and X drugs
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作者 Yang Jianzhou Xie Rihua +4 位作者 Daniel Krewski Wang Yongjin mark walker Cao Wenjun Shi Wu Wen 《Chinese Medical Journal》 SCIE CAS CSCD 2014年第4期702-706,共5页
Background Changing health care providers frequently breaks the continuity of care,which is associated with many health care problems.The purpose of this study was to examine the association between a change of health... Background Changing health care providers frequently breaks the continuity of care,which is associated with many health care problems.The purpose of this study was to examine the association between a change of health care providers and pregnancy exposure to FDA category C,D and X drugs.Methods A 50% random sample of women who gave a birth in Saskatchewan between January 1,1997 and December 31,2000 were chosen for this study.The association between the number of changes in health care providers and with pregnancy exposure to category C,D,and X drugs for those women with and without chronic diseases were evaluated using multiple logistical regression,with adjusted odds ratios (ORs) and its 95% confidence intervals (C/s) as the association measures.Results A total of 18 568 women were included in this study.Rates of FDA C,D,and X drug uses were 14.35%,17.07%,21.72%,and 31.14%,in women with no change of provider,1-2 changes,3-5 changes,and more than 5 changes of health care providers.An association between the number of changes of health care providers and pregnancy exposure to FDA C,D,and X drugs existed in women without chronic diseases but not in women with chronic disease.Conclusion Change of health care providers is associated with pregnancy exposure to FDA category C,D and X drugs in women without chronic diseases. 展开更多
关键词 change health care providers prescription drugs FDA pregnancy risk classification PREGNANCY
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Advancing pediatric care before birth
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作者 Kun Sun mark walker +3 位作者 Yongjun Zhang Tao Duan Luming Sun Jun Zhang 《Frontiers of Medicine》 SCIE CSCD 2023年第2期352-354,共3页
The concept of perinatology was first brought up by Dr.Erich Saling in the 1970s[1].It bridges between prenatal and postnatal periods and commonly covers from 28 weeks of gestation to 28 days postpartum.The formation ... The concept of perinatology was first brought up by Dr.Erich Saling in the 1970s[1].It bridges between prenatal and postnatal periods and commonly covers from 28 weeks of gestation to 28 days postpartum.The formation of perinatology has led to close collaboration between obstetricians and neonatologists for the wellbeing of the mother and newborn.Despite the close ties,the role of a neonatologist tends to be passive until a baby is born. 展开更多
关键词 MOTHER PEDIATRIC BRIDGES
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