A synthesis method for nanosized forsterite(Mg_(2)SiO_(4))doped with varying concentrations of Ni and Co has been developed to support studies of carbonation-based extraction and separation of Ni and Co from mafic and...A synthesis method for nanosized forsterite(Mg_(2)SiO_(4))doped with varying concentrations of Ni and Co has been developed to support studies of carbonation-based extraction and separation of Ni and Co from mafic and ultramafic rocks.The protocol expands upon an existing sol-gel/surfactant method and is demonstrated for doping levels of 5%and 25%of Ni or Co.Variables such as metal reagents,surfactant ratios,and calcination procedures were optimized to achieve high specific surface areas and small particle sizes while minimizing secondary phase formation.Particle sizes ranged from 29 to 83 nm,and specific surface areas were between 11 and 32 m^(2) g^(−1).Metal oxide impurities were minimal,appearing only in undoped and 25%Ni-doped samples at 0.6 wt%or less.Ni and Co were only detected in the+Ⅱ oxidation state and partitioned predominantly in the M1 cation site of the forsterite crystal structure.Doped nanosized forsterites prepared with this method will enable in situ experiments that can track,at the molecular scale,the fate of Ni and Co during carbonation reactions and thus provide a knowledge base for improving metal extraction and separation technologies.展开更多
Point-of-care(POC)detection of herbicides is of great importance due to their impact on the environment and potential risks to human health.Here,we design a single-atomic site catalyst(SASC)with excellent peroxidase-l...Point-of-care(POC)detection of herbicides is of great importance due to their impact on the environment and potential risks to human health.Here,we design a single-atomic site catalyst(SASC)with excellent peroxidase-like(POD-like)catalytic activity,which enhances the detection performance of corresponding lateral flow immunoassay(LFIA).The iron single-atomic site catalyst(Fe-SASC)is synthesized from hemin-doped ZIF-8,creating active sites that mimic the Fe active center coordination environment of natural enzyme and their functions.Due to its atomically dispersed iron active sites that result in maximum utilization of active metal atoms,the Fe-SASC exhibits superior POD-like activity,which has great potential to replace its natural counterparts.Also,the catalytic mechanism of Fe-SASC is systematically investigated.Utilizing its outstanding catalytic activity,the Fe-SASC is used as label to construct LFIA(Fe-SASC-LFIA)for herbicide detection.The 2,4-dichlorophenoxyacetic acid(2,4-D)is selected as a target here,since it is a commonly used herbicide as well as a biomarker for herbicide exposure evaluation.A linear detection range of 1-250 ng/mL with a low limit of detection(LOD)of 0.82 ng/mL has been achieved.Meanwhile,excellent specificity and selectivity towards 2,4-D have been obtained.The outstanding detection performance of the Fe-SASC-LFIA has also been demonstrated in the detection of human urine samples,indicating the practicability of this POC detection platform for analyzing the 2,4-D exposure level of a person.We believe this proposed Fe-SASC-LFIA has potential as a portable,rapid,and high-sensitive POC detection strategy for pesticide exposure evaluation.展开更多
基金supported by the U.S.Department of Energy,Office of Science,Office of Basic Energy Sciences,Chemical and Materials Sciences to Advance Clean Energy Technologies and Low-Carbon Manufacturing(FWP 80281)Pacific Northwest National Laboratory(PNNL)is operated for the DOE by Battelle Memorial Institute under contract DE-AC05-76RL01830+1 种基金A portion of this research was performed on a project award(10.46936/lser.proj.2023.60770/60008927)from the Environmental Molecular Sciences Laboratory,a DOE Office of Science User Facility sponsored by the Biological and Environmental Research program under Contract No.DE-AC05-76RL01830supported by the Science Undergraduate Laboratory Internships program(SULI)of the U.S.Department of Energy,Office of Science,Office of Workforce Development for Teachers and Scientists(WDTS).
文摘A synthesis method for nanosized forsterite(Mg_(2)SiO_(4))doped with varying concentrations of Ni and Co has been developed to support studies of carbonation-based extraction and separation of Ni and Co from mafic and ultramafic rocks.The protocol expands upon an existing sol-gel/surfactant method and is demonstrated for doping levels of 5%and 25%of Ni or Co.Variables such as metal reagents,surfactant ratios,and calcination procedures were optimized to achieve high specific surface areas and small particle sizes while minimizing secondary phase formation.Particle sizes ranged from 29 to 83 nm,and specific surface areas were between 11 and 32 m^(2) g^(−1).Metal oxide impurities were minimal,appearing only in undoped and 25%Ni-doped samples at 0.6 wt%or less.Ni and Co were only detected in the+Ⅱ oxidation state and partitioned predominantly in the M1 cation site of the forsterite crystal structure.Doped nanosized forsterites prepared with this method will enable in situ experiments that can track,at the molecular scale,the fate of Ni and Co during carbonation reactions and thus provide a knowledge base for improving metal extraction and separation technologies.
基金support from the National Institute of Environmental Health Sciences of the US National Institutes of Health(Award Number 1R43ES031885-01)。
文摘Point-of-care(POC)detection of herbicides is of great importance due to their impact on the environment and potential risks to human health.Here,we design a single-atomic site catalyst(SASC)with excellent peroxidase-like(POD-like)catalytic activity,which enhances the detection performance of corresponding lateral flow immunoassay(LFIA).The iron single-atomic site catalyst(Fe-SASC)is synthesized from hemin-doped ZIF-8,creating active sites that mimic the Fe active center coordination environment of natural enzyme and their functions.Due to its atomically dispersed iron active sites that result in maximum utilization of active metal atoms,the Fe-SASC exhibits superior POD-like activity,which has great potential to replace its natural counterparts.Also,the catalytic mechanism of Fe-SASC is systematically investigated.Utilizing its outstanding catalytic activity,the Fe-SASC is used as label to construct LFIA(Fe-SASC-LFIA)for herbicide detection.The 2,4-dichlorophenoxyacetic acid(2,4-D)is selected as a target here,since it is a commonly used herbicide as well as a biomarker for herbicide exposure evaluation.A linear detection range of 1-250 ng/mL with a low limit of detection(LOD)of 0.82 ng/mL has been achieved.Meanwhile,excellent specificity and selectivity towards 2,4-D have been obtained.The outstanding detection performance of the Fe-SASC-LFIA has also been demonstrated in the detection of human urine samples,indicating the practicability of this POC detection platform for analyzing the 2,4-D exposure level of a person.We believe this proposed Fe-SASC-LFIA has potential as a portable,rapid,and high-sensitive POC detection strategy for pesticide exposure evaluation.
