Introduction: The purpose of this retrospective study is to identify medical conditions impacting neurodevelopmental outcomes of extremely low birth weight and very low birth weight preterm infants at three years of a...Introduction: The purpose of this retrospective study is to identify medical conditions impacting neurodevelopmental outcomes of extremely low birth weight and very low birth weight preterm infants at three years of age. Methods: Infants born in Banner Diamond Children’s University Medical Center, receiving services in the Newborn Intensive Care Unit, and attending Neonatal Developmental Follow-Up Clinic were identified. Participants received developmental assessment and follow-up from August 2012 through December 2018. Relevant clinical conditions during initial hospital stay and up to three years of age were obtained by reviewing medical and developmental records. Bayley Scales of Infant Toddler Development (Bayley III) was used to evaluate skill development at 6, 9, 12, 18, 24, 30, 36 months. Results: Data analysis did not reveal significant p-values;it did demonstrate that some predictor variables impact neurodevelopmental outcomes in cognitive, language and motor skill development. Conclusion: This retrospective study reports significant association between birth weight and low cognitive scores. Correlations were also found between gestational age and Total Language, and the longer an infant stayed in the NICU, the poorer the Total Language Scaled Scores at 8 to 12 months, 15 to 18 months, and 24 to 36 months. Birth weight was found to be the greatest predictor of poor motor scores.展开更多
Several methods have been described in the literature to both evaluate and document progression in keratoconus,but there is no consistent or clear definition of ectasia progression.The authors describe how modern corn...Several methods have been described in the literature to both evaluate and document progression in keratoconus,but there is no consistent or clear definition of ectasia progression.The authors describe how modern corneal tomography,including both anterior and posterior elevation and pachymetric data can be used to screen for ectatic progression,and how software programs such as the Enhanced Reference Surface and the Belin-Ambrosio Enhanced Ectasia Display(BAD)can be employed to detect earlier changes.Additionally,in order to describe specific quantitative values that can be used as progression determinants,the normal noise measurement of the three parameters(corneal thickness at the thinnest point,anterior and posterior radius of curvature(ARC,PRC)taken from the 3.0 mm optical zone centered on the thinnest point),was assessed.These values were obtained by imaging five normal patients using three different technicians on three separate days.The 95%and 80%one-sided confidence intervals for all three parameters were surprisingly small(7.88/4.03μm for corneal thickness,0.024/0.012 mm for ARC,and 0.083/0.042 mm for PRC),suggesting that they may perform well as progression determinants.展开更多
文摘Introduction: The purpose of this retrospective study is to identify medical conditions impacting neurodevelopmental outcomes of extremely low birth weight and very low birth weight preterm infants at three years of age. Methods: Infants born in Banner Diamond Children’s University Medical Center, receiving services in the Newborn Intensive Care Unit, and attending Neonatal Developmental Follow-Up Clinic were identified. Participants received developmental assessment and follow-up from August 2012 through December 2018. Relevant clinical conditions during initial hospital stay and up to three years of age were obtained by reviewing medical and developmental records. Bayley Scales of Infant Toddler Development (Bayley III) was used to evaluate skill development at 6, 9, 12, 18, 24, 30, 36 months. Results: Data analysis did not reveal significant p-values;it did demonstrate that some predictor variables impact neurodevelopmental outcomes in cognitive, language and motor skill development. Conclusion: This retrospective study reports significant association between birth weight and low cognitive scores. Correlations were also found between gestational age and Total Language, and the longer an infant stayed in the NICU, the poorer the Total Language Scaled Scores at 8 to 12 months, 15 to 18 months, and 24 to 36 months. Birth weight was found to be the greatest predictor of poor motor scores.
文摘Several methods have been described in the literature to both evaluate and document progression in keratoconus,but there is no consistent or clear definition of ectasia progression.The authors describe how modern corneal tomography,including both anterior and posterior elevation and pachymetric data can be used to screen for ectatic progression,and how software programs such as the Enhanced Reference Surface and the Belin-Ambrosio Enhanced Ectasia Display(BAD)can be employed to detect earlier changes.Additionally,in order to describe specific quantitative values that can be used as progression determinants,the normal noise measurement of the three parameters(corneal thickness at the thinnest point,anterior and posterior radius of curvature(ARC,PRC)taken from the 3.0 mm optical zone centered on the thinnest point),was assessed.These values were obtained by imaging five normal patients using three different technicians on three separate days.The 95%and 80%one-sided confidence intervals for all three parameters were surprisingly small(7.88/4.03μm for corneal thickness,0.024/0.012 mm for ARC,and 0.083/0.042 mm for PRC),suggesting that they may perform well as progression determinants.
