Multiple sclerosis(MS)is the most common inflammatory demyelinating brain disease.The occurrence of psychiatric disorders,especially for major depression,in the course of MS is high.Reports concerning bipolar disorder...Multiple sclerosis(MS)is the most common inflammatory demyelinating brain disease.The occurrence of psychiatric disorders,especially for major depression,in the course of MS is high.Reports concerning bipolar disorder(BD)remain rather scarce although early descriptions were found in the old neurological literature.The purpose of this article is to provide a critical review of the epidemiology,comorbidity,and treatment findings regarding BD preceding the onset of MS.展开更多
文摘Multiple sclerosis(MS)is the most common inflammatory demyelinating brain disease.The occurrence of psychiatric disorders,especially for major depression,in the course of MS is high.Reports concerning bipolar disorder(BD)remain rather scarce although early descriptions were found in the old neurological literature.The purpose of this article is to provide a critical review of the epidemiology,comorbidity,and treatment findings regarding BD preceding the onset of MS.