AIM To analyse clinical and long-term oncologic results after laparoscopic complete mesocolic excision(CME)for colonic cancer over a 10-year period.METHODS Consecutive patients who received laparoscopic CME at our hos...AIM To analyse clinical and long-term oncologic results after laparoscopic complete mesocolic excision(CME)for colonic cancer over a 10-year period.METHODS Consecutive patients who received laparoscopic CME at our hospital from 2007 to 2017 were prospectively registered and retrospectively analysed.In total,341 patients were included with tumour-nodal-metastasis(TNM)stages 0-Ⅲ.RESULTS The mean age of the patients was 71.9 years.The median length of stay was 5 d.The mean lymph node harvest was 17.8.The mortality rate was 1.2%.Fifteen patients were reoperated on for anastomotic leaks.The local recurrence rate was 2.3%.Five-year TTR and cancer-specific survival CSS were 83.1%and 90.3%.The location of the tumour was not a significant variable for survival in unadjusted and adjusted survival analysis.TNM stage and anastomotic leaks were significant variables with respect to survival.CONCLUSION Laparoscopic CME results in acceptable complication rates and long-term oncologic results.It is important to avoid anastomotic leaks because of their negative effect on survival.展开更多
文摘AIM To analyse clinical and long-term oncologic results after laparoscopic complete mesocolic excision(CME)for colonic cancer over a 10-year period.METHODS Consecutive patients who received laparoscopic CME at our hospital from 2007 to 2017 were prospectively registered and retrospectively analysed.In total,341 patients were included with tumour-nodal-metastasis(TNM)stages 0-Ⅲ.RESULTS The mean age of the patients was 71.9 years.The median length of stay was 5 d.The mean lymph node harvest was 17.8.The mortality rate was 1.2%.Fifteen patients were reoperated on for anastomotic leaks.The local recurrence rate was 2.3%.Five-year TTR and cancer-specific survival CSS were 83.1%and 90.3%.The location of the tumour was not a significant variable for survival in unadjusted and adjusted survival analysis.TNM stage and anastomotic leaks were significant variables with respect to survival.CONCLUSION Laparoscopic CME results in acceptable complication rates and long-term oncologic results.It is important to avoid anastomotic leaks because of their negative effect on survival.