Efficient photocatalytic reduction of CO_(2)is crucial to decrease the atmospheric concentration of CO_(2).Pairing this process with H_(2)O_(2)production is of considerable importance for simultaneously producing valu...Efficient photocatalytic reduction of CO_(2)is crucial to decrease the atmospheric concentration of CO_(2).Pairing this process with H_(2)O_(2)production is of considerable importance for simultaneously producing value-added chemicals.However,the photocatalysts reported for such a process suffer from a high recombination rate of the surface/bulk charges,as well as inefficient enrichment and activation toward CO_(2)and O_(2),resulting in low conversion efficiency even in the presence of organic sacrificial agents and expensive metal co-catalysts.Herein,two 1,3,5-triphenylbenzene-based organic polymers with high ionic density and porosity are prepared through a facile Sonogashira polymerization.The ionic imidazolium sites embedded in the polymeric skeleton provide the two polymers(iCMP-1 and iCMP-2)with adsorptive selectivity for CO_(2)/N_(2) up to 98-102 at 273 K,facilitating the enrichment of CO_(2)and O_(2)molecules around the catalytic centers,thus boosting their catalytic conversion directly from air under solar light(100 mW cm^(-2)).Benefiting from the improved charge separation and broad light absorption,along with high CO_(2)and O_(2)uptake,iCMP-2 can deliver excellent CO and H_(2)O_(2)yields(611.8 and 810.6μmol h^(-1)g^(-1),respectively)under an atmosphere composed of water vapor and air without any co-catalysts.展开更多
Exploration of efficient and stable photocatalysts to mimic natural leaves for the conversion of atmospheric CO_(2)into hydrocarbons utilizing solar light is very important but remains a major challenge.Herein,we repo...Exploration of efficient and stable photocatalysts to mimic natural leaves for the conversion of atmospheric CO_(2)into hydrocarbons utilizing solar light is very important but remains a major challenge.Herein,we report the design of four novel metal-salen-incorporated conjugated microporous polymers as robust artificial leaves for photoreduction of atmospheric CO_(2)with gaseous water.Owing to the rich nitrogen and oxygen moieties in the polymeric frameworks,they show a maximum CO_(2)adsorption capacity of 46.1 cm3 g^(−1)and adsorption selectivity for CO_(2)/N_(2)of up to 82 at 273 K.Under air atmosphere and simulated solar light(100mWcm^(−2)),TEPT-Zn shows an excellent CO yield of 304.96μmol h^(−1)g^(−1)with a selectivity of approximately 100%,which represents one of the best results in terms of organic photocatalysts for gas-phase CO_(2)photoreduction so far.Furthermore,only small degradation in the CO yield is observed even after 120-h continuous illumination.More importantly,a good CO yield of 152.52μmol g^(−1)was achieved by directly exposing the photocatalytic reaction of TEPT-Zn in an outdoor environment for 3 h(25-28℃,52.3±7.9mWcm^(−2)).This work provides an avenue for the continued development of advanced polymers toward gas-phase photoconversion of CO_(2)from air.展开更多
A total of 43 prolonged coma patients with diffuse axonal injury received the somatosensory evoked potential examination one month after injury in the First Affiliated Hospital, School of Medicine, Zhejiang University...A total of 43 prolonged coma patients with diffuse axonal injury received the somatosensory evoked potential examination one month after injury in the First Affiliated Hospital, School of Medicine, Zhejiang University in China. Somatosensory evoked potentials were graded as normal, abnormal or absent （grades I-III） according to N20 amplitude and central conduction time. The outcome in patients with grade III somatosensory evoked potential was in each case unfavorable. The prognostic accuracy of grade III somatosensory evoked potential for unfavorable and non-awakening outcome was 100% and 80%, respectively. The prognostic accuracy of grade I somatosensory evoked potential for favorable and wakening outcome was 86% and 100%, respectively. These results suggest that somatosensory evoked potential grade is closely correlated with coma severity and degree of recovery. Somatosensory evoked potential is a valuable diagnostic tool to assess prognosis in prolonged coma patients with diffuse axonal injury.展开更多
The present study established a rat cortical neuronal model of in vitro mechanical injury.At 30 minutes after injury,the survival rate of the injured cortical neurons was decreased compared with normal neurons,and was...The present study established a rat cortical neuronal model of in vitro mechanical injury.At 30 minutes after injury,the survival rate of the injured cortical neurons was decreased compared with normal neurons,and was gradually decreased with aggravated degree of injury.Reverse transcription-polymerase chain reaction results showed that at 1 hour after injury,there was increased expression of metabotropic glutamate receptor la in cortical neurons.Immunohistochemical staining results showed that at 30 minutes after injury,the number of metabotropic glutamate receptor 1a-positive cells increased compared with normal neurons.At 12 hours after injury,lactate dehydrogenase activity in the(RS)-l-aminoindan-1,5-dicarboxylic acid(AIDA)-treated injury neurons was si[jnificantly decreased than that in the pure injury group.At 1 hour after injury,intracellular free Ca"+concentration was markedly decreased in the AIDA-treated injury neurons than that in the pure injury neurons.These findings suggest that after mechanical injury to cortical neurons,metabotropic glutamate receptor la expression increased.The resulting increase in intracellular free Ca2+concentration was blocked by AIDA,indicating that AIDA exhibits neuroprotective effects after mechanical injury.展开更多
The diffuse brain injury model was conducted in Sprague-Dawley rats, according to Marmarou's free-fall attack. The water content in brain tissue, expression of metabotropic glutamate receptor la mRNA and protein w...The diffuse brain injury model was conducted in Sprague-Dawley rats, according to Marmarou's free-fall attack. The water content in brain tissue, expression of metabotropic glutamate receptor la mRNA and protein were significantly increased after injury, reached a peak at 24 hours, and then gradually decreased. After treatment with the competitive antagonist of metabotropic glutamate receptor la, (RS)-l-aminoindan-1,5-dicarboxylic acid, the water content of brain tissues decreased between 12-72 hours after injury, and neurological behaviors improved at 2 weeks. These experimental findings suggest that the 1-aminoindan-1, 5-dicarboxylic acid may result in marked neuroprotection against diffuse brain injury.展开更多
基金supported by the Excellent Youth Foundation of Jiangxi Scientific Committee(no.20232ACB213012)National Science Foundation of Jiangxi Province of China(no.20242BAB25236)+2 种基金Jiangxi Talent Program(no.DHSQT32022005)Beijing Institute of Technology Research Fund Program for Young Scholars(XSQD-202215006)National Natural Science Foundation of China(no.22202008 and 22202039).
文摘Efficient photocatalytic reduction of CO_(2)is crucial to decrease the atmospheric concentration of CO_(2).Pairing this process with H_(2)O_(2)production is of considerable importance for simultaneously producing value-added chemicals.However,the photocatalysts reported for such a process suffer from a high recombination rate of the surface/bulk charges,as well as inefficient enrichment and activation toward CO_(2)and O_(2),resulting in low conversion efficiency even in the presence of organic sacrificial agents and expensive metal co-catalysts.Herein,two 1,3,5-triphenylbenzene-based organic polymers with high ionic density and porosity are prepared through a facile Sonogashira polymerization.The ionic imidazolium sites embedded in the polymeric skeleton provide the two polymers(iCMP-1 and iCMP-2)with adsorptive selectivity for CO_(2)/N_(2) up to 98-102 at 273 K,facilitating the enrichment of CO_(2)and O_(2)molecules around the catalytic centers,thus boosting their catalytic conversion directly from air under solar light(100 mW cm^(-2)).Benefiting from the improved charge separation and broad light absorption,along with high CO_(2)and O_(2)uptake,iCMP-2 can deliver excellent CO and H_(2)O_(2)yields(611.8 and 810.6μmol h^(-1)g^(-1),respectively)under an atmosphere composed of water vapor and air without any co-catalysts.
基金Research Foundation for Advanced Talents of East China University of Technology,Grant/Award Number:DHBK201927Excellent Youth Foundation of Jiangxi Scientific Committee,Grant/Award Number:20232ACB213012+2 种基金National Science Foundation for Young Scientists of China,Grant/Award Number:21905122National Science Foundation for Young Scientists,Grant/Award Number:21905147Jiangxi Talent Program,Grant/Award Number:DHSQT32022005.
文摘Exploration of efficient and stable photocatalysts to mimic natural leaves for the conversion of atmospheric CO_(2)into hydrocarbons utilizing solar light is very important but remains a major challenge.Herein,we report the design of four novel metal-salen-incorporated conjugated microporous polymers as robust artificial leaves for photoreduction of atmospheric CO_(2)with gaseous water.Owing to the rich nitrogen and oxygen moieties in the polymeric frameworks,they show a maximum CO_(2)adsorption capacity of 46.1 cm3 g^(−1)and adsorption selectivity for CO_(2)/N_(2)of up to 82 at 273 K.Under air atmosphere and simulated solar light(100mWcm^(−2)),TEPT-Zn shows an excellent CO yield of 304.96μmol h^(−1)g^(−1)with a selectivity of approximately 100%,which represents one of the best results in terms of organic photocatalysts for gas-phase CO_(2)photoreduction so far.Furthermore,only small degradation in the CO yield is observed even after 120-h continuous illumination.More importantly,a good CO yield of 152.52μmol g^(−1)was achieved by directly exposing the photocatalytic reaction of TEPT-Zn in an outdoor environment for 3 h(25-28℃,52.3±7.9mWcm^(−2)).This work provides an avenue for the continued development of advanced polymers toward gas-phase photoconversion of CO_(2)from air.
基金funded by Zhejiang Medicines &Health Sciences Research Fund (Class A) in 2009, No.2009A086
文摘A total of 43 prolonged coma patients with diffuse axonal injury received the somatosensory evoked potential examination one month after injury in the First Affiliated Hospital, School of Medicine, Zhejiang University in China. Somatosensory evoked potentials were graded as normal, abnormal or absent （grades I-III） according to N20 amplitude and central conduction time. The outcome in patients with grade III somatosensory evoked potential was in each case unfavorable. The prognostic accuracy of grade III somatosensory evoked potential for unfavorable and non-awakening outcome was 100% and 80%, respectively. The prognostic accuracy of grade I somatosensory evoked potential for favorable and wakening outcome was 86% and 100%, respectively. These results suggest that somatosensory evoked potential grade is closely correlated with coma severity and degree of recovery. Somatosensory evoked potential is a valuable diagnostic tool to assess prognosis in prolonged coma patients with diffuse axonal injury.
文摘The present study established a rat cortical neuronal model of in vitro mechanical injury.At 30 minutes after injury,the survival rate of the injured cortical neurons was decreased compared with normal neurons,and was gradually decreased with aggravated degree of injury.Reverse transcription-polymerase chain reaction results showed that at 1 hour after injury,there was increased expression of metabotropic glutamate receptor la in cortical neurons.Immunohistochemical staining results showed that at 30 minutes after injury,the number of metabotropic glutamate receptor 1a-positive cells increased compared with normal neurons.At 12 hours after injury,lactate dehydrogenase activity in the(RS)-l-aminoindan-1,5-dicarboxylic acid(AIDA)-treated injury neurons was si[jnificantly decreased than that in the pure injury group.At 1 hour after injury,intracellular free Ca"+concentration was markedly decreased in the AIDA-treated injury neurons than that in the pure injury neurons.These findings suggest that after mechanical injury to cortical neurons,metabotropic glutamate receptor la expression increased.The resulting increase in intracellular free Ca2+concentration was blocked by AIDA,indicating that AIDA exhibits neuroprotective effects after mechanical injury.
文摘The diffuse brain injury model was conducted in Sprague-Dawley rats, according to Marmarou's free-fall attack. The water content in brain tissue, expression of metabotropic glutamate receptor la mRNA and protein were significantly increased after injury, reached a peak at 24 hours, and then gradually decreased. After treatment with the competitive antagonist of metabotropic glutamate receptor la, (RS)-l-aminoindan-1,5-dicarboxylic acid, the water content of brain tissues decreased between 12-72 hours after injury, and neurological behaviors improved at 2 weeks. These experimental findings suggest that the 1-aminoindan-1, 5-dicarboxylic acid may result in marked neuroprotection against diffuse brain injury.
