Objective:To explore the key points of holistic nursing for children with membranous nephropathy(MN)combined with cerebral venous thrombosis,providing a reference for similar cases.Methods:The course of illness data o...Objective:To explore the key points of holistic nursing for children with membranous nephropathy(MN)combined with cerebral venous thrombosis,providing a reference for similar cases.Methods:The course of illness data of an 8-year-old boy with MN in the recurrent phase complicated with cerebral venous sinus thrombosis(CVST)was retroactively analyzed.Systematic nursing was implemented based on evidence-based practices,including strict neurological monitoring,anticoagulation and thrombolysis medication nursing,fluid and electrolyte management,hypoalbuminemia and edema nursing,complication prevention,and mental health education.Results:After 16 days of continuous infusion of low molecular weight heparin and supportive treatment,the child’s symptoms,such as headache and vomiting,disappeared.The reexamination of MRV showed significant absorption of thrombosis,and there was no residual neurological deficit.During the 3-month follow-up,the anticoagulation compliance was good,and there was no recurrence.Conclusion:Early identification of hypercoagulability risk,strengthening dynamic evaluation of neurological signs and coagulation indicators,standardizing anticoagulation and thrombolysis nursing,and cooperating with continuous health management can significantly improve the prognosis of children with MN combined with CVST.展开更多
Head and neck squamous cell carcinoma(HNSCC),as the most common type(>90%)of head and neck cancer,includes various epithelial malignancies that arise in the nasal cavity,oral cavity,pharynx,and larynx.In 2020,appro...Head and neck squamous cell carcinoma(HNSCC),as the most common type(>90%)of head and neck cancer,includes various epithelial malignancies that arise in the nasal cavity,oral cavity,pharynx,and larynx.In 2020,approximately 878000 new cases and 444000 deaths linked to HNSCC occurred worldwide(Sung et al.,2021).Due to the associated frequent recurrence and metastasis.展开更多
High pressure and high temperature(HPHT)technology,as an extreme physical condition,plays an important role in regulating the properties of materials,having the advantages of enhancing doping efficiency,refining grain...High pressure and high temperature(HPHT)technology,as an extreme physical condition,plays an important role in regulating the properties of materials,having the advantages of enhancing doping efficiency,refining grain size,and manufacturing defects,therefore it is quite necessary to study the effectiveness on tuning thermoelectric properties.Elemental telluride,a potential candidate for thermoelectric materials,has the poor doping efficiency and high resistivity,which become an obstacle for practical applications.Here,we report the realization of a dual optimization of electrical behaviors and thermal conductivity through HPHT method combining with the introduction of black phosphorus.The results show the maximum zT of 0.65 and an average zT of 0.42(300 K–610 K),which are increased by 55%and 68%in the synthesis pressure regulation system,respectively.This study clarifies that the HPHT method has significant advantages in modulating the thermoelectric parameters,providing a reference for seeking high performance thermoelectric materials.展开更多
As a sister compound of PbTe, SnTe possesses the environmentally friendly elements. However, the pristine SnTe compounds suffer from the high carrier concentration, the large valence band offset between the L and Σpo...As a sister compound of PbTe, SnTe possesses the environmentally friendly elements. However, the pristine SnTe compounds suffer from the high carrier concentration, the large valence band offset between the L and Σpositions and high thermal conductivity. Using high-pressure and high-temperature technology, we synthesized the pristine SnTe samples at different pressures and systemically investigated their thermoelectric properties.High pressure induces rich microstructures, including the high-density dislocations and lattice distortions, which serve as the strong phonon scattering centers, thereby reducing the lattice thermal conductivity. For the electrical properties, pressure reduces the harmful high carrier concentration, due to the depression of Sn vacancies.Moreover, pressure induces the valence band convergence, reducing the energy separation between the L and Σpositions. The band convergence and suppressed carrier concentration increase the Seebeck coefficient. Thus, the power factors of pressure-sintered compounds do not deteriorate significantly under the condition of decreasing electrical conductivity. Ultimately, for a pristine SnTe compound synthesized at 5 GPa, a higher ZT value of 0.51 is achieved at 750 K, representing a 140% improvement compared to the value of 0.21 obtained using SPS. Therefore, the high-pressure and high-temperature technology is demonstrated as an effectively approach to optimize thermoelectric performance.展开更多
文摘Objective:To explore the key points of holistic nursing for children with membranous nephropathy(MN)combined with cerebral venous thrombosis,providing a reference for similar cases.Methods:The course of illness data of an 8-year-old boy with MN in the recurrent phase complicated with cerebral venous sinus thrombosis(CVST)was retroactively analyzed.Systematic nursing was implemented based on evidence-based practices,including strict neurological monitoring,anticoagulation and thrombolysis medication nursing,fluid and electrolyte management,hypoalbuminemia and edema nursing,complication prevention,and mental health education.Results:After 16 days of continuous infusion of low molecular weight heparin and supportive treatment,the child’s symptoms,such as headache and vomiting,disappeared.The reexamination of MRV showed significant absorption of thrombosis,and there was no residual neurological deficit.During the 3-month follow-up,the anticoagulation compliance was good,and there was no recurrence.Conclusion:Early identification of hypercoagulability risk,strengthening dynamic evaluation of neurological signs and coagulation indicators,standardizing anticoagulation and thrombolysis nursing,and cooperating with continuous health management can significantly improve the prognosis of children with MN combined with CVST.
基金This work was supported by the National Natural Science Foundation of China(No.U2004136)the Supporting Program for Central Plain Young Top Talents(No.ZYQR201912176),the Program for Innovative Talents of Science and Technology in Henan Province(No.18HASTIT048)+2 种基金the Program for Science and Technology Development in Henan Province(Nos.212102310150,202102310063,and SBGJ2018041)the Kaifeng Science and Technology Project(No.1908001)the Supporting Grant of Henan University(Nos.2018YLJC01,2019YLXKJC01,and 2020YLZDYJ14),China.
文摘Head and neck squamous cell carcinoma(HNSCC),as the most common type(>90%)of head and neck cancer,includes various epithelial malignancies that arise in the nasal cavity,oral cavity,pharynx,and larynx.In 2020,approximately 878000 new cases and 444000 deaths linked to HNSCC occurred worldwide(Sung et al.,2021).Due to the associated frequent recurrence and metastasis.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11804185,11974208,52172212,52102335,and 52002217)the Natural Science Foundation of Shandong Province,China(Grant Nos.ZR2020YQ05,ZR2019MA054,2019KJJ020,ZR2021YQ03,and 2022KJA043)。
文摘High pressure and high temperature(HPHT)technology,as an extreme physical condition,plays an important role in regulating the properties of materials,having the advantages of enhancing doping efficiency,refining grain size,and manufacturing defects,therefore it is quite necessary to study the effectiveness on tuning thermoelectric properties.Elemental telluride,a potential candidate for thermoelectric materials,has the poor doping efficiency and high resistivity,which become an obstacle for practical applications.Here,we report the realization of a dual optimization of electrical behaviors and thermal conductivity through HPHT method combining with the introduction of black phosphorus.The results show the maximum zT of 0.65 and an average zT of 0.42(300 K–610 K),which are increased by 55%and 68%in the synthesis pressure regulation system,respectively.This study clarifies that the HPHT method has significant advantages in modulating the thermoelectric parameters,providing a reference for seeking high performance thermoelectric materials.
基金supported by the National Natural Science Foundation of China (Grant Nos. 12374012, 11974208, 52172212, and 52002217)Shandong Provincial Natural Science Foundation (Grant Nos. ZR2023JQ001, ZR2020YQ05, and 2019KJJ020)financial support from the Program of Distinguished Expert of Taishan Scholar (Grant No. tstp20221124)。
文摘As a sister compound of PbTe, SnTe possesses the environmentally friendly elements. However, the pristine SnTe compounds suffer from the high carrier concentration, the large valence band offset between the L and Σpositions and high thermal conductivity. Using high-pressure and high-temperature technology, we synthesized the pristine SnTe samples at different pressures and systemically investigated their thermoelectric properties.High pressure induces rich microstructures, including the high-density dislocations and lattice distortions, which serve as the strong phonon scattering centers, thereby reducing the lattice thermal conductivity. For the electrical properties, pressure reduces the harmful high carrier concentration, due to the depression of Sn vacancies.Moreover, pressure induces the valence band convergence, reducing the energy separation between the L and Σpositions. The band convergence and suppressed carrier concentration increase the Seebeck coefficient. Thus, the power factors of pressure-sintered compounds do not deteriorate significantly under the condition of decreasing electrical conductivity. Ultimately, for a pristine SnTe compound synthesized at 5 GPa, a higher ZT value of 0.51 is achieved at 750 K, representing a 140% improvement compared to the value of 0.21 obtained using SPS. Therefore, the high-pressure and high-temperature technology is demonstrated as an effectively approach to optimize thermoelectric performance.
