Dementia is a neurological disorder that affects the brain and its functioning,and women experience its effects more than men do.Preventive care often requires non-invasive and rapid tests,yet conventional diagnostic ...Dementia is a neurological disorder that affects the brain and its functioning,and women experience its effects more than men do.Preventive care often requires non-invasive and rapid tests,yet conventional diagnostic techniques are time-consuming and invasive.One of the most effective ways to diagnose dementia is by analyzing a patient’s speech,which is cheap and does not require surgery.This research aims to determine the effectiveness of deep learning(DL)and machine learning(ML)structures in diagnosing dementia based on women’s speech patterns.The study analyzes data drawn from the Pitt Corpus,which contains 298 dementia files and 238 control files from the Dementia Bank database.Deep learning models and SVM classifiers were used to analyze the available audio samples in the dataset.Our methodology used two methods:a DL-ML model and a single DL model for the classification of diabetics and a single DL model.The deep learning model achieved an astronomic level of accuracy of 99.99%with an F1 score of 0.9998,Precision of 0.9997,and recall of 0.9998.The proposed DL-ML fusion model was equally impressive,with an accuracy of 99.99%,F1 score of 0.9995,Precision of 0.9998,and recall of 0.9997.Also,the study reveals how to apply deep learning and machine learning models for dementia detection from speech with high accuracy and low computational complexity.This research work,therefore,concludes by showing the possibility of using speech-based dementia detection as a possibly helpful early diagnosis mode.For even further enhanced model performance and better generalization,future studies may explore real-time applications and the inclusion of other components of speech.展开更多
Glaucoma disease causes irreversible damage to the optical nerve and it has the potential to cause permanent loss of vision.Glaucoma ranks as the second most prevalent cause of permanent blindness.Traditional glaucoma...Glaucoma disease causes irreversible damage to the optical nerve and it has the potential to cause permanent loss of vision.Glaucoma ranks as the second most prevalent cause of permanent blindness.Traditional glaucoma diagnosis requires a highly experienced specialist,costly equipment,and a lengthy wait time.For automatic glaucoma detection,state-of-the-art glaucoma detection methods include a segmentation-based method to calculate the cup-to-disc ratio.Other methods include multi-label segmentation networks and learning-based methods and rely on hand-crafted features.Localizing the optic disc(OD)is one of the key features in retinal images for detecting retinal diseases,especially for glaucoma disease detection.The approach presented in this study is based on deep classifiers for OD segmentation and glaucoma detection.First,the optic disc detection process is based on object detection using a Mask Region-Based Convolutional Neural Network(Mask-RCNN).The OD detection task was validated using the Dice score,intersection over union,and accuracy metrics.The OD region is then fed into the second stage for glaucoma detection.Therefore,considering only the OD area for glaucoma detection will reduce the number of classification artifacts by limiting the assessment to the optic disc area.For this task,VGG-16(Visual Geometry Group),Resnet-18(Residual Network),and Inception-v3 were pre-trained and fine-tuned.We also used the Support Vector Machine Classifier.The feature-based method uses region content features obtained by Histogram of Oriented Gradients(HOG)and Gabor Filters.The final decision is based on weighted fusion.A comparison of the obtained results from all classification approaches is provided.Classification metrics including accuracy and ROC curve are compared for each classification method.The novelty of this research project is the integration of automatic OD detection and glaucoma diagnosis in a global method.Moreover,the fusion-based decision system uses the glaucoma detection result obtained using several convolutional deep neural networks and the support vector machine classifier.These classification methods contribute to producing robust classification results.This method was evaluated using well-known retinal images available for research work and a combined dataset including retinal images with and without pathology.The performance of the models was tested on two public datasets and a combined dataset and was compared to similar research.The research findings show the potential of this methodology in the early detection of glaucoma,which will reduce diagnosis time and increase detection efficiency.The glaucoma assessment achieves about 98%accuracy in the classification rate,which is close to and even higher than that of state-of-the-art methods.The designed detection model may be used in telemedicine,healthcare,and computer-aided diagnosis systems.展开更多
基金funded by the Deanship of Scientific Research at Princess Nourah bint Abdulrahman University,through the Research Groups Program Grant No.(RGP-1444-0057).
文摘Dementia is a neurological disorder that affects the brain and its functioning,and women experience its effects more than men do.Preventive care often requires non-invasive and rapid tests,yet conventional diagnostic techniques are time-consuming and invasive.One of the most effective ways to diagnose dementia is by analyzing a patient’s speech,which is cheap and does not require surgery.This research aims to determine the effectiveness of deep learning(DL)and machine learning(ML)structures in diagnosing dementia based on women’s speech patterns.The study analyzes data drawn from the Pitt Corpus,which contains 298 dementia files and 238 control files from the Dementia Bank database.Deep learning models and SVM classifiers were used to analyze the available audio samples in the dataset.Our methodology used two methods:a DL-ML model and a single DL model for the classification of diabetics and a single DL model.The deep learning model achieved an astronomic level of accuracy of 99.99%with an F1 score of 0.9998,Precision of 0.9997,and recall of 0.9998.The proposed DL-ML fusion model was equally impressive,with an accuracy of 99.99%,F1 score of 0.9995,Precision of 0.9998,and recall of 0.9997.Also,the study reveals how to apply deep learning and machine learning models for dementia detection from speech with high accuracy and low computational complexity.This research work,therefore,concludes by showing the possibility of using speech-based dementia detection as a possibly helpful early diagnosis mode.For even further enhanced model performance and better generalization,future studies may explore real-time applications and the inclusion of other components of speech.
基金Deanship of Scientific Research,Princess Nourah bint Abdulrahman University,through the Program of Research Project Funding after Publication,Grant No(43-PRFA-P-31).
文摘Glaucoma disease causes irreversible damage to the optical nerve and it has the potential to cause permanent loss of vision.Glaucoma ranks as the second most prevalent cause of permanent blindness.Traditional glaucoma diagnosis requires a highly experienced specialist,costly equipment,and a lengthy wait time.For automatic glaucoma detection,state-of-the-art glaucoma detection methods include a segmentation-based method to calculate the cup-to-disc ratio.Other methods include multi-label segmentation networks and learning-based methods and rely on hand-crafted features.Localizing the optic disc(OD)is one of the key features in retinal images for detecting retinal diseases,especially for glaucoma disease detection.The approach presented in this study is based on deep classifiers for OD segmentation and glaucoma detection.First,the optic disc detection process is based on object detection using a Mask Region-Based Convolutional Neural Network(Mask-RCNN).The OD detection task was validated using the Dice score,intersection over union,and accuracy metrics.The OD region is then fed into the second stage for glaucoma detection.Therefore,considering only the OD area for glaucoma detection will reduce the number of classification artifacts by limiting the assessment to the optic disc area.For this task,VGG-16(Visual Geometry Group),Resnet-18(Residual Network),and Inception-v3 were pre-trained and fine-tuned.We also used the Support Vector Machine Classifier.The feature-based method uses region content features obtained by Histogram of Oriented Gradients(HOG)and Gabor Filters.The final decision is based on weighted fusion.A comparison of the obtained results from all classification approaches is provided.Classification metrics including accuracy and ROC curve are compared for each classification method.The novelty of this research project is the integration of automatic OD detection and glaucoma diagnosis in a global method.Moreover,the fusion-based decision system uses the glaucoma detection result obtained using several convolutional deep neural networks and the support vector machine classifier.These classification methods contribute to producing robust classification results.This method was evaluated using well-known retinal images available for research work and a combined dataset including retinal images with and without pathology.The performance of the models was tested on two public datasets and a combined dataset and was compared to similar research.The research findings show the potential of this methodology in the early detection of glaucoma,which will reduce diagnosis time and increase detection efficiency.The glaucoma assessment achieves about 98%accuracy in the classification rate,which is close to and even higher than that of state-of-the-art methods.The designed detection model may be used in telemedicine,healthcare,and computer-aided diagnosis systems.
