High-voltage LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811)cathodes are critical for enhancing the energy density of lithium-ion batteries(LIBs).The development of binders compatible with high-voltage NCM811 cathode material...High-voltage LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811)cathodes are critical for enhancing the energy density of lithium-ion batteries(LIBs).The development of binders compatible with high-voltage NCM811 cathode materials is crucial to enhance the electrochemical performance of LIBs.However,the traditional fluoropolymer binder,poly(vinylidene difluoride)(PVDF),can potentially leach components or break down into poly(fluoroalkyl substances)(PFAS)chemicals,thereby contributing to PFAS contamination.A novel fluorine-free polymer,polysulfone-polyamide-polyimide(SPIO),was designed and synthesized as a binder for NCM811 cathodes.The SPIO binder exhibits exceptional mechanical properties and superior electrochemical characteristics.The cathode film fabricated with SPIO demonstrated a remarkable delamination force of 8 N(390 N·m^(-1)),indicating robust adhesion.The Li‖NCM811 cell incorporating the SPIO binder retained 80%of its initial capacity after 300 cycles at a current density of 0.2 C.In comparison,the control cells assem bled with the PVDF binder retained only 52%of their capacities under the same cycling conditions.Furthermore,the SPIO binder exhibited improved compatibility with the electrolyte.Transmission electron microscopy analysis of the cathode films after 100 cycles revealed the formation of a unifo rm,dense,and continuous chemical-electrochemical interface(CEI)by the SPIO binder on the surface of the NCM811 particles,which significantly contributed to the enhancement of the electrochemical performance.These results highlight the potential of SPIO as an advanced binder material for high-perfo rmance lithium-ion batteries.展开更多
Battery models are of great importance to develop portable computing systems,for whether the design of low power hardware architecture or the design of battery-aware scheduling policies.In this paper,we present a phys...Battery models are of great importance to develop portable computing systems,for whether the design of low power hardware architecture or the design of battery-aware scheduling policies.In this paper,we present a physically justified iterative computing method to illustrate the discharge,recovery and charge process of Li/Li-ion batteries.The discharge and recovery processes correspond well to an existing accurate analytical battery model:R-V-W's analytical model,and thus interpret this model algorithmically.Our method can also extend R-V-W's model easily to accommodate the charge process.The work will help the system designers to grasp the characteristics of R-V-W's battery model and also,enable to predict the battery behavior in the charge process in a uniform way as the discharge process and the recovery process.Experiments are performed to show the ac-curacy of the extended model by comparing the predicted charge times with those derived from the DUALFOIL simulations.Various profiles with different combinations of battery modes were tested.The experimental results show that the extended battery model preserves high accuracy in predicting the charge behavior.展开更多
Objective:To provide basic information and theories for prehypertension early intervention,a systematic analysis of the epidemic status and risk factors among young and middle-aged was carried out here.Methods:This st...Objective:To provide basic information and theories for prehypertension early intervention,a systematic analysis of the epidemic status and risk factors among young and middle-aged was carried out here.Methods:This study relied on the data bank of a health check-up population of a class a tertiary general hospital in Guangdong province in 2015.Total 9540 young and middle-aged adults were enrolled,and 733 people were included to find out the effect with lifestyle in these crowd.Principal Components Analysis(PCA)of Factor(FA)was used to identify dietary patterns.The logistic regression model was used to find the risk factors of prehypertension.Results:Among 9540 young and middle-aged cases,the incidence of prehypertension was 36.6%.Moreover,the average age,proportion of male gender,overweight,FBG(fasting blood glucose),dyslipidemia,and hyperuricemia were significantly higher in the prehypertension group than in the optimal BP group.Multivariate logistic regression analysis indicated that age,total cholesterol,triglycerides,uric acid,body mass index and HR(heart rate)were risk factors,and female was a protective factor for prehypertension.Among 733 cases,the incidence of prehypertension was 35.1%.The proportion of smoking,drinking,physical workers,moderate and severe physical activity,and the intake of meat,dietary energy were significantly higher in the prehypertension group than in the optimal BP group.Dietary patterns included“meat model”,“spice model”,“main vegeTables model”and“high protein model”.Multivariate logistic regression analysis indicated that age,drinking were risk factors for prehypertension,while dietary milk intake,dietary magnesium intake were protective factors.Conclusions:Prehypertension is highly prevalent in Guangzhou.However,education about effective lifestyle modifications as an alcohol limit,increasing the intake of dairy products,and magnesium may intervene in the development of prehypertension.But how to develop targeted interventions for such groups need to be further explored.The present study would lay the theoretical foundation and basic data for the next step.展开更多
We present a new design strategy to synthesize ladder-type thienoacenaphthopyrazine(TAP)-based monomers through two different coupling reactions from starting material 5,6-dibromoacenaphthylene-1,2-dione.By bringing v...We present a new design strategy to synthesize ladder-type thienoacenaphthopyrazine(TAP)-based monomers through two different coupling reactions from starting material 5,6-dibromoacenaphthylene-1,2-dione.By bringing varous electron-deficient groups together(such as five-membered aromatic rings,pyrazine,fluorine,and thiadiazols),this new family of molecules exhibits good stability in ambient conditions and easily tunes the electronic,photophysical and film-forming properties of polymers.The unique molecular shape with its extendedπ-conjugated backbone perpendicular to the polymer chain,offers a remarkable platform for the development of a semiconducting polymer with rare geometry.The planar and enlarged conjugated backbone enables TAP-based copolymers PTAP1 and PTAP2 to exhibit distinguishing solubility properties that are different from small-molecule-based polymers,indicating the advantages of novel ladder-type monomers.Their insolubility in chloroform supports orthogonal solvent processing to fabricate layer-by-layer organic solar cells(LBL-OSCs).Owing to its shorterπ–πstacking distance,higher hole mobility,and more favorable phase separation caused bymultifluorine substitution,polymer PTAP1-based LBL-OSC exhibits the highest efficiency of 17.14%by using Y6-BO as the electron acceptor while the efficiency for the PTAP2-based device is 14.20%.This high efficiency indicates the tremendous potential of these novel building units.展开更多
Photodynamic therapy(PDT)has emerged as a prominent modality in the therapeutic armamentarium against malignant tumors,particularly those originating from the cutaneous and mucosal tissues(1).The principle of PDT invo...Photodynamic therapy(PDT)has emerged as a prominent modality in the therapeutic armamentarium against malignant tumors,particularly those originating from the cutaneous and mucosal tissues(1).The principle of PDT involves the administration of a photosensitizing agent that selectively accumulates within neoplastic cells(2).Upon exposure to laser light of specific wavelengths,the photosensitizer becomes activated,triggering the generation of reactive oxygen species(ROS)such as oxygen radicals(3).This process culminates in cellular damage and subsequent tumor destruction.PDT holds promise as a localized therapeutic option for unresectable or recurrent cholangiocarcinomas(4).展开更多
TANGQIAO is a township of Zhangjiagang City, Jiangsu Province. Ordinary in other ways, this town is unusual for the number of weiqi (go) players it boasts—8,000 of its population of 28,000. Almost every family has mo...TANGQIAO is a township of Zhangjiagang City, Jiangsu Province. Ordinary in other ways, this town is unusual for the number of weiqi (go) players it boasts—8,000 of its population of 28,000. Almost every family has more than one weiqi enthusiast. In recent years, the township’s players have earned themselves uncountable championships and runner-up placements at provincial-and national-level weiqi competitions. Thus, the State Physical Culture and Sports Commission awarded Zhangjiagang City the title "National Home of Weiqi" in July, 1990. In May of 1991, the Jiangsu Physical Culture展开更多
基金supported by the Shenzhen Science and Technology Program(No.JCYJ20220818100407016)the National Natural Science Foundation of China(No.22275059)+1 种基金Guangdong Special Support Program(No.2021TX06L775)high-level special funds(No.G03050K002)。
文摘High-voltage LiNi_(0.8)Co_(0.1)Mn_(0.1)O_(2)(NCM811)cathodes are critical for enhancing the energy density of lithium-ion batteries(LIBs).The development of binders compatible with high-voltage NCM811 cathode materials is crucial to enhance the electrochemical performance of LIBs.However,the traditional fluoropolymer binder,poly(vinylidene difluoride)(PVDF),can potentially leach components or break down into poly(fluoroalkyl substances)(PFAS)chemicals,thereby contributing to PFAS contamination.A novel fluorine-free polymer,polysulfone-polyamide-polyimide(SPIO),was designed and synthesized as a binder for NCM811 cathodes.The SPIO binder exhibits exceptional mechanical properties and superior electrochemical characteristics.The cathode film fabricated with SPIO demonstrated a remarkable delamination force of 8 N(390 N·m^(-1)),indicating robust adhesion.The Li‖NCM811 cell incorporating the SPIO binder retained 80%of its initial capacity after 300 cycles at a current density of 0.2 C.In comparison,the control cells assem bled with the PVDF binder retained only 52%of their capacities under the same cycling conditions.Furthermore,the SPIO binder exhibited improved compatibility with the electrolyte.Transmission electron microscopy analysis of the cathode films after 100 cycles revealed the formation of a unifo rm,dense,and continuous chemical-electrochemical interface(CEI)by the SPIO binder on the surface of the NCM811 particles,which significantly contributed to the enhancement of the electrochemical performance.These results highlight the potential of SPIO as an advanced binder material for high-perfo rmance lithium-ion batteries.
基金Project partly supported by the Key Program of the National NaturalScience Foundation of China (No. 60533040)the National Natural Science Funds for Distinguished Young Scholar (No. 60525202)+1 种基金the Program for New Century Excellent Talents in University (No. NCET-04-0545)the Key Scientific and Technological Project of Hangzhou Technology Bureau (No. 20062412B01),China
文摘Battery models are of great importance to develop portable computing systems,for whether the design of low power hardware architecture or the design of battery-aware scheduling policies.In this paper,we present a physically justified iterative computing method to illustrate the discharge,recovery and charge process of Li/Li-ion batteries.The discharge and recovery processes correspond well to an existing accurate analytical battery model:R-V-W's analytical model,and thus interpret this model algorithmically.Our method can also extend R-V-W's model easily to accommodate the charge process.The work will help the system designers to grasp the characteristics of R-V-W's battery model and also,enable to predict the battery behavior in the charge process in a uniform way as the discharge process and the recovery process.Experiments are performed to show the ac-curacy of the extended model by comparing the predicted charge times with those derived from the DUALFOIL simulations.Various profiles with different combinations of battery modes were tested.The experimental results show that the extended battery model preserves high accuracy in predicting the charge behavior.
基金The study was carried out as a collaborative study supported by First Affiliated Hospital of Guangdong Pharmaceutical University.The authors express their sincere gratitude to all the staffs in this survey for their important contribution.Funding sources:The authors gratefully acknowledge financial support from Natural Science Foundation of Guangdong Province(No.2016A030313808).
文摘Objective:To provide basic information and theories for prehypertension early intervention,a systematic analysis of the epidemic status and risk factors among young and middle-aged was carried out here.Methods:This study relied on the data bank of a health check-up population of a class a tertiary general hospital in Guangdong province in 2015.Total 9540 young and middle-aged adults were enrolled,and 733 people were included to find out the effect with lifestyle in these crowd.Principal Components Analysis(PCA)of Factor(FA)was used to identify dietary patterns.The logistic regression model was used to find the risk factors of prehypertension.Results:Among 9540 young and middle-aged cases,the incidence of prehypertension was 36.6%.Moreover,the average age,proportion of male gender,overweight,FBG(fasting blood glucose),dyslipidemia,and hyperuricemia were significantly higher in the prehypertension group than in the optimal BP group.Multivariate logistic regression analysis indicated that age,total cholesterol,triglycerides,uric acid,body mass index and HR(heart rate)were risk factors,and female was a protective factor for prehypertension.Among 733 cases,the incidence of prehypertension was 35.1%.The proportion of smoking,drinking,physical workers,moderate and severe physical activity,and the intake of meat,dietary energy were significantly higher in the prehypertension group than in the optimal BP group.Dietary patterns included“meat model”,“spice model”,“main vegeTables model”and“high protein model”.Multivariate logistic regression analysis indicated that age,drinking were risk factors for prehypertension,while dietary milk intake,dietary magnesium intake were protective factors.Conclusions:Prehypertension is highly prevalent in Guangzhou.However,education about effective lifestyle modifications as an alcohol limit,increasing the intake of dairy products,and magnesium may intervene in the development of prehypertension.But how to develop targeted interventions for such groups need to be further explored.The present study would lay the theoretical foundation and basic data for the next step.
基金This work was supported by the National Natural Science Foundation of China(grant no.22179076)the Fund for Zhujiang Young Scholar(grant no.18220203)+1 种基金the Natural Science Foundation of Guangdong Province(grant no.2022A1515011803)the Department of Education of Guangdong Province(grant nos.2021KCXTD032 and 2019KCXTD007).
文摘We present a new design strategy to synthesize ladder-type thienoacenaphthopyrazine(TAP)-based monomers through two different coupling reactions from starting material 5,6-dibromoacenaphthylene-1,2-dione.By bringing varous electron-deficient groups together(such as five-membered aromatic rings,pyrazine,fluorine,and thiadiazols),this new family of molecules exhibits good stability in ambient conditions and easily tunes the electronic,photophysical and film-forming properties of polymers.The unique molecular shape with its extendedπ-conjugated backbone perpendicular to the polymer chain,offers a remarkable platform for the development of a semiconducting polymer with rare geometry.The planar and enlarged conjugated backbone enables TAP-based copolymers PTAP1 and PTAP2 to exhibit distinguishing solubility properties that are different from small-molecule-based polymers,indicating the advantages of novel ladder-type monomers.Their insolubility in chloroform supports orthogonal solvent processing to fabricate layer-by-layer organic solar cells(LBL-OSCs).Owing to its shorterπ–πstacking distance,higher hole mobility,and more favorable phase separation caused bymultifluorine substitution,polymer PTAP1-based LBL-OSC exhibits the highest efficiency of 17.14%by using Y6-BO as the electron acceptor while the efficiency for the PTAP2-based device is 14.20%.This high efficiency indicates the tremendous potential of these novel building units.
基金supported by the Natural Science Foundation of Hunan Province(2024JJ4095)Scientific Research Project of Hunan Provincial Health Commission(202204010011 and B202303027830)Project Program of National Clinical Research Center for Geriatric Disorders(2022LNJJ19).
文摘Photodynamic therapy(PDT)has emerged as a prominent modality in the therapeutic armamentarium against malignant tumors,particularly those originating from the cutaneous and mucosal tissues(1).The principle of PDT involves the administration of a photosensitizing agent that selectively accumulates within neoplastic cells(2).Upon exposure to laser light of specific wavelengths,the photosensitizer becomes activated,triggering the generation of reactive oxygen species(ROS)such as oxygen radicals(3).This process culminates in cellular damage and subsequent tumor destruction.PDT holds promise as a localized therapeutic option for unresectable or recurrent cholangiocarcinomas(4).
文摘TANGQIAO is a township of Zhangjiagang City, Jiangsu Province. Ordinary in other ways, this town is unusual for the number of weiqi (go) players it boasts—8,000 of its population of 28,000. Almost every family has more than one weiqi enthusiast. In recent years, the township’s players have earned themselves uncountable championships and runner-up placements at provincial-and national-level weiqi competitions. Thus, the State Physical Culture and Sports Commission awarded Zhangjiagang City the title "National Home of Weiqi" in July, 1990. In May of 1991, the Jiangsu Physical Culture
