Aerosol particle pollution has become an increasing serious environmental problem,and urban vegetation plays a long-lasting and positive role in mitigating it.This study compared the particle capture abilities of tree...Aerosol particle pollution has become an increasing serious environmental problem,and urban vegetation plays a long-lasting and positive role in mitigating it.This study compared the particle capture abilities of trees,shrubs,and herbs,and examined the compositions and influence of aerosol particles accumulated on leaf functional traits.Retained particles primarily contained Ca^(2+),K^(+),SO_(4)^(2-),NO_(3)^(-)and NH_(4)^(+),indicating their anthropogenic origins.The leathery-leaved tree Osmanthus fragrans and the papery-leaved herb Alternanthera sessilis demonstrated the higher competence in particle accumulation than other plants,and leaf morphologic structures(e.g.,leaf grooves,trichomes,waxy layers,and stomata characteristics)were closely associated with particle capture by plant species.Particle retention negatively impacted stomata,impeding photosynthesis,and reducing transpiration.In response to particle accumulation,plants tended to decrease specific leaf area and adjust stomatal conductance.Both growth form and leaf texture significantly influenced the particle capture abilities of different plant species.The substantial contribution of plants,particularly herbs in the lower vegetation strata,to particle removal should not be overlooked.Vegetation with a tree-shrub-herb configuration excels at particle capture,offering potential advantages in mitigating particle pollution and enhancing ecological benefits.展开更多
Electroacupuncture at Shangjuxu (ST37) and Tianshu (ST25) can improve visceral hypersensitivity in rats. Colorectal distension was used to establish a rat model of chronic visceral hypersensitivity. Immunohistoche...Electroacupuncture at Shangjuxu (ST37) and Tianshu (ST25) can improve visceral hypersensitivity in rats. Colorectal distension was used to establish a rat model of chronic visceral hypersensitivity. Immunohistochemistry was used to detect P2X2 and P2X3 receptor expression in dorsal root ganglia from rats with chronic visceral hypersensitivity. Results demonstrated that abdominal withdrawal reflex scores obviously increased following establishment of the model, indicating visceral hypersensitivity. Simultaneously, P2X2 and P2X3 receptor expression increased in dorsal root ganglia. After bilateral electroacupuncture at Shangjuxu and Tianshu, abdominal withdrawal reflex scores and P2X2 and P2X3 receptor expression decreased in rats with visceral hypersensitivity. These results indicated that electroacupuncture treatment improved visceral hypersensitivity in rats with irritable bowel syndrome by reducing P2X2 and P2X3 receptor expression in dorsal root ganglia.展开更多
The convective heat transfer of supercritical-pressure RP-3(Rocket Propellant 3)aviation kerosene in a horizontal circular tube has been numerically studied,focusing mainly on the non-uniform heat transfer deteriorati...The convective heat transfer of supercritical-pressure RP-3(Rocket Propellant 3)aviation kerosene in a horizontal circular tube has been numerically studied,focusing mainly on the non-uniform heat transfer deterioration along the circumferential direction.The governing equations of mass,momentum and energy have been solved using the pressure-based segregated solver based on the finite volume method.The re-normalization group(RNG)k-εturbulence model with an enhanced wall treatment was selected.Considering the heat conduction in the solid wall,the mechanism of heat transfer deterioration and the buoyancy effect on deteriorated heat transfer were discussed.The evolution of secondary flow was analyzed.Effects of the outer-wall heat flux,mass flux,pressure and tube thermal conductivity on heat transfer were investigated.Moreover,the buoyancy criterion and the heat transfer correlation were obtained.Results indicate that the poor flow performance of near-wall fluid causes the pseudo-film boiling,further leads to the heat transfer deterioration.The strong buoyancy has an effect of enhancing the heat transfer at the bottom of tube,and weakening the heat transfer at the top of tube,which results in the non-uniform inner-wall temperature and heat flux distributions.Decreasing the ratio of outer-wall heat flux and mass flux,increasing the pressure could weaken the heat transfer difference along the circumferential direction,while the effect of thermal conductivity of tube on the circumferential parameters distributions is more complicated.When the buoyancy criterion of(Grq/Grth)max≤0.8 is satisfied,the effect of buoyancy could be ignored.The new correlations work well for non-uniform heat transfer predictions.展开更多
Since the advent of artificial intelligence(AI)technology,it has been constantly studied and has achieved rapid development.The AI assistant system is expected to improve the quality of automatic polyp detection and c...Since the advent of artificial intelligence(AI)technology,it has been constantly studied and has achieved rapid development.The AI assistant system is expected to improve the quality of automatic polyp detection and classification.It could also help prevent endoscopists from missing polyps and make an accurate optical diagnosis.These functions provided by AI could result in a higher adenoma detection rate and decrease the cost of polypectomy for hyperplastic polyps.In addition,AI has good performance in the staging,diagnosis,and segmentation of colorectal cancer.This article provides an overview of recent research focusing on the application of AI in colorectal polyps and cancer and highlights the advances achieved.展开更多
The phenomena associated with the entrainment of free-stream turbulence (FST) into boundary-layer flows are relevant for a number of subjects. It has been be- lieved that the continuous spectra of the Orr-Sommerfeld...The phenomena associated with the entrainment of free-stream turbulence (FST) into boundary-layer flows are relevant for a number of subjects. It has been be- lieved that the continuous spectra of the Orr-Sommerfeld (O-S)/Squire equations describe the entrainment process, and thus they are used to specify the inlet condition in simulation of bypass transition. However, Dong and Wu (Dong, M. and Wu, X. On continuous spectra of the Orr-Sommerfeld/Squire equations and entrainment of free-stream vortical disturbances. Journal of Fluid Mechanics, 732, 616-659 (2013)) pointed out that continuous spectra exhibit several non-physical features due to neglecting the non-parallelism. They further proposed a large-Reynolds-number asymptotic approach, and showed that the non-parallelism is a leading-order effect even for the short-wavelength disturbance, for which the response concentrates in the edge layer. In this paper, the asymptotic solution is verified numerically by studying its evolution in incompressible boundary layers. It is found that the numerical results can be accurately predicted by the asymptotic solution, implying that the latter is adequate for moderate Reynolds numbers. By introducing a series of such solutions as the inflow perturbations, the bypass transition is investigated via the direct numerical simulation (DNS). The transition processes, including the evolution of streaks, the amplification of secondary-instability modes, and the emergence of turbulent spots, agree with the experimental observations.展开更多
Circular RNA(circRNA)is a newly discovered non-coding RNA with special structure,which is widely expressed in eukaryotic organisms and mainly located in the cytoplasm.circRNAs participate in gene regulation by working...Circular RNA(circRNA)is a newly discovered non-coding RNA with special structure,which is widely expressed in eukaryotic organisms and mainly located in the cytoplasm.circRNAs participate in gene regulation by working as miRNA sponges that block the inhibitory effect of miRNA on its target genes.In addition,circRNAs can bind to RNA binding proteins to regulate gene expression.Based on characteristics of stability,expression specificity and participation in gene regulation,circRNAs are expected to be biomarkers for early diagnosis of cancer or potential targets for cancer therapy.With the help of bioinformatics analysis,circRNA microarray analysis and high-throughput sequencing technology,more circRNAs were discovered to participate in the progression of gastric cancer(GC)over the past three years.This article gives an overview of these recent research focusing on the roles of circRNAs in GC and highlights the advances.展开更多
Forward-/backward-facing steps in boundary-layer flows are often seen in engineering applications, and they have potential impacts on laminar-turbulent transition through scattering of the oncoming instability modes(e...Forward-/backward-facing steps in boundary-layer flows are often seen in engineering applications, and they have potential impacts on laminar-turbulent transition through scattering of the oncoming instability modes(e.g., Tollmien-Schlichting(T-S) waves). This issue is studied in the present paper by applying a local scattering framework, which is a rather generic mathematical framework on describing the mode scattering process. In this framework, a high-Reynolds-number triple-deck formalism is employed, and a transmission coefficient, defined as the ratio of the asymptotic amplitude of the instability mode downstream of the step to that upstream, is introduced. Through the systematical study, it has been found that both the forward-and backward-facing steps have a destabilizing effect on the oncoming T-S waves in subsonic boundary layers, this effect increases with the height of the step and/or the frequency of the T-S wave, and a backward-facing step(BFS) always has a greater impact than a forward-facing step(FFS). These facts agree with most of the previous investigations.However, one numerical study(WORNER, A., RIST, U., and WAGNER, S. Humps/steps influence on stability characteristics of two-dimensional laminar boundary layer. AIAA Journal, 41, 192–197(2003)), which was based on an ad-hoc configuration, showed an opposite impact of an FFS. Through the investigation on the specific configuration, it is revealed that the wrong conclusion was drawn by misinterpreting the numerical results.展开更多
Background:Understanding the mechanisms underlying community assembly is helpful for conservation and restoration of communities,particularly those that contain rare and endangered species like Taxus fuana,which are e...Background:Understanding the mechanisms underlying community assembly is helpful for conservation and restoration of communities,particularly those that contain rare and endangered species like Taxus fuana,which are endemic to the Western Himalayas.The niche(limiting similarity)vs.neutral(randomness)assembly of the T.fuana forest community in Gyirong County,Tibet,China,was investigated.The net relatedness index(NRI)was calculated using a phylogenetic tree.The phylogenetic characteristics of the community and its relationships with environment were analyzed.Results:The value of the mean NRI at the community level was less than-1.96,indicating that the phylogenetic structure was overdispersed;whereas majority of the NRIs at the tree,shrub,and herb layers were within-1.96 to1.96,indicating random dispersion.Environmental factors accounted for 44.38%,46.52%,24.04%,and 14.07%of the variation at the community level,tree,shrub,and herb layer,respectively.The phylogenetic structure at the community level and tree layer were significantly influenced by both topographic and soil factors,while shrub and herb layers tended to be affected by a single environmental factor.Conclusions:Community assembly of the T.fuana forest was simultaneously affected by niche and neutral processes,and their variations were closely related to the environment.Neutral process dominated community assembly in the shrub and herb layers.However,the interaction of limiting similarity and randomness played a dominant role at the community level and tree layer;and contributed to maintenance of biodiversity stability.The synergy of multiple environmental factors had a more obvious influence on community assembly than individual environmental factors,especially at the community level.These findings would help to understand the conservation of rare and endangered tree species,such as T.fuana,in the native community;and highlight the importance of random and non-random processes in assembly and biodiversity maintenance of alpine plant communities.展开更多
Label-free nanopore sensors have emerged as a new generation technology of DNA sequencing and have been widely used for single molecule analysis.Since the firstα-hemolysin biological nanopore,various types of nanopor...Label-free nanopore sensors have emerged as a new generation technology of DNA sequencing and have been widely used for single molecule analysis.Since the firstα-hemolysin biological nanopore,various types of nanopores made of different materials have been under extensive development.Noise represents a common challenge among all types of nanopore sensors.The nanopore noise can be decomposed into four components in the frequency domain(1/f noise,white noise,dielectric noise,and amplifier noise).In this work,we reviewed and summarized the physicalmodels,origins,and reduction methods for each of these noise components.For the first time,we quantitatively benchmarked the root mean square(RMS)noise levels for different types of nanopores,demonstrating a clear material-dependent RMS noise.We anticipate this review article will enhance the understanding of nanopore sensor noises and provide an informative tutorial for developing future nanopore sensors with a high signal-to-noise ratio.展开更多
The laminar-turbulent transition in boundary-layer flows is often affected by wall imperfections, because the latter may interact with either the freestream perturbations or the oncoming boundary-layer instability mod...The laminar-turbulent transition in boundary-layer flows is often affected by wall imperfections, because the latter may interact with either the freestream perturbations or the oncoming boundary-layer instability modes, leading to a modification of the accumulation of the normal modes. The present paper particularly focuses on the latter mechanism in a transonic boundary layer, namely, the effect of a two-dimensional(2 D) roughness element on the oncoming Tollmien-Schlichting(T-S) modes when they propagate through the region of the rapid mean-flow distortion induced by the roughness. The wave scattering is analyzed by adapting the local scattering theory developed for subsonic boundary layers(WU, X. S. and DONG, M. A local scattering theory for the effects of isolated roughness on boundary-layer instability and transition: transmission coefficient as an eigenvalue. Journal of Fluid Mechanics, 794, 68–108(2006)) to the transonic regime, and a transmission coefficient is introduced to characterize the effect of the roughness. In the sub-transonic regime, in which the Mach number is close to, but less than, 1, the scattering system reduces to an eigenvalue problem with the transmission coefficient being the eigenvalue;while in the super-transonic regime, in which the Mach number is slightly greater than 1, the scattering system becomes a high-dimensional group of linear equations with the transmission coefficient being solved afterward. In the largeReynolds-number asymptotic theory, the K′arm′an-Guderley parameter is introduced to quantify the effect of the Mach number. A systematical parametric study is carried out,and the dependence of the transmission coefficient on the roughness shape, the frequency of the oncoming mode, and the K′arm′an-Guderley parameter is provided.展开更多
基金supported by the National Natural Science Foundation of China(No.31700475).
文摘Aerosol particle pollution has become an increasing serious environmental problem,and urban vegetation plays a long-lasting and positive role in mitigating it.This study compared the particle capture abilities of trees,shrubs,and herbs,and examined the compositions and influence of aerosol particles accumulated on leaf functional traits.Retained particles primarily contained Ca^(2+),K^(+),SO_(4)^(2-),NO_(3)^(-)and NH_(4)^(+),indicating their anthropogenic origins.The leathery-leaved tree Osmanthus fragrans and the papery-leaved herb Alternanthera sessilis demonstrated the higher competence in particle accumulation than other plants,and leaf morphologic structures(e.g.,leaf grooves,trichomes,waxy layers,and stomata characteristics)were closely associated with particle capture by plant species.Particle retention negatively impacted stomata,impeding photosynthesis,and reducing transpiration.In response to particle accumulation,plants tended to decrease specific leaf area and adjust stomatal conductance.Both growth form and leaf texture significantly influenced the particle capture abilities of different plant species.The substantial contribution of plants,particularly herbs in the lower vegetation strata,to particle removal should not be overlooked.Vegetation with a tree-shrub-herb configuration excels at particle capture,offering potential advantages in mitigating particle pollution and enhancing ecological benefits.
基金funded by the National Natural Science Foundation of China,No.30973783the Shanghai Municipal Scientific Committee Project,No.11ZR1434300the Key Subject Program of State Administration of Traditional Chinese Medicine
文摘Electroacupuncture at Shangjuxu (ST37) and Tianshu (ST25) can improve visceral hypersensitivity in rats. Colorectal distension was used to establish a rat model of chronic visceral hypersensitivity. Immunohistochemistry was used to detect P2X2 and P2X3 receptor expression in dorsal root ganglia from rats with chronic visceral hypersensitivity. Results demonstrated that abdominal withdrawal reflex scores obviously increased following establishment of the model, indicating visceral hypersensitivity. Simultaneously, P2X2 and P2X3 receptor expression increased in dorsal root ganglia. After bilateral electroacupuncture at Shangjuxu and Tianshu, abdominal withdrawal reflex scores and P2X2 and P2X3 receptor expression decreased in rats with visceral hypersensitivity. These results indicated that electroacupuncture treatment improved visceral hypersensitivity in rats with irritable bowel syndrome by reducing P2X2 and P2X3 receptor expression in dorsal root ganglia.
基金support from the National Natural Science Foundation of China(No.51576027)。
文摘The convective heat transfer of supercritical-pressure RP-3(Rocket Propellant 3)aviation kerosene in a horizontal circular tube has been numerically studied,focusing mainly on the non-uniform heat transfer deterioration along the circumferential direction.The governing equations of mass,momentum and energy have been solved using the pressure-based segregated solver based on the finite volume method.The re-normalization group(RNG)k-εturbulence model with an enhanced wall treatment was selected.Considering the heat conduction in the solid wall,the mechanism of heat transfer deterioration and the buoyancy effect on deteriorated heat transfer were discussed.The evolution of secondary flow was analyzed.Effects of the outer-wall heat flux,mass flux,pressure and tube thermal conductivity on heat transfer were investigated.Moreover,the buoyancy criterion and the heat transfer correlation were obtained.Results indicate that the poor flow performance of near-wall fluid causes the pseudo-film boiling,further leads to the heat transfer deterioration.The strong buoyancy has an effect of enhancing the heat transfer at the bottom of tube,and weakening the heat transfer at the top of tube,which results in the non-uniform inner-wall temperature and heat flux distributions.Decreasing the ratio of outer-wall heat flux and mass flux,increasing the pressure could weaken the heat transfer difference along the circumferential direction,while the effect of thermal conductivity of tube on the circumferential parameters distributions is more complicated.When the buoyancy criterion of(Grq/Grth)max≤0.8 is satisfied,the effect of buoyancy could be ignored.The new correlations work well for non-uniform heat transfer predictions.
文摘Since the advent of artificial intelligence(AI)technology,it has been constantly studied and has achieved rapid development.The AI assistant system is expected to improve the quality of automatic polyp detection and classification.It could also help prevent endoscopists from missing polyps and make an accurate optical diagnosis.These functions provided by AI could result in a higher adenoma detection rate and decrease the cost of polypectomy for hyperplastic polyps.In addition,AI has good performance in the staging,diagnosis,and segmentation of colorectal cancer.This article provides an overview of recent research focusing on the application of AI in colorectal polyps and cancer and highlights the advances achieved.
基金Project supported by the National Natural Science Foundation of China(Nos.11472189 and11332007)
文摘The phenomena associated with the entrainment of free-stream turbulence (FST) into boundary-layer flows are relevant for a number of subjects. It has been be- lieved that the continuous spectra of the Orr-Sommerfeld (O-S)/Squire equations describe the entrainment process, and thus they are used to specify the inlet condition in simulation of bypass transition. However, Dong and Wu (Dong, M. and Wu, X. On continuous spectra of the Orr-Sommerfeld/Squire equations and entrainment of free-stream vortical disturbances. Journal of Fluid Mechanics, 732, 616-659 (2013)) pointed out that continuous spectra exhibit several non-physical features due to neglecting the non-parallelism. They further proposed a large-Reynolds-number asymptotic approach, and showed that the non-parallelism is a leading-order effect even for the short-wavelength disturbance, for which the response concentrates in the edge layer. In this paper, the asymptotic solution is verified numerically by studying its evolution in incompressible boundary layers. It is found that the numerical results can be accurately predicted by the asymptotic solution, implying that the latter is adequate for moderate Reynolds numbers. By introducing a series of such solutions as the inflow perturbations, the bypass transition is investigated via the direct numerical simulation (DNS). The transition processes, including the evolution of streaks, the amplification of secondary-instability modes, and the emergence of turbulent spots, agree with the experimental observations.
文摘Circular RNA(circRNA)is a newly discovered non-coding RNA with special structure,which is widely expressed in eukaryotic organisms and mainly located in the cytoplasm.circRNAs participate in gene regulation by working as miRNA sponges that block the inhibitory effect of miRNA on its target genes.In addition,circRNAs can bind to RNA binding proteins to regulate gene expression.Based on characteristics of stability,expression specificity and participation in gene regulation,circRNAs are expected to be biomarkers for early diagnosis of cancer or potential targets for cancer therapy.With the help of bioinformatics analysis,circRNA microarray analysis and high-throughput sequencing technology,more circRNAs were discovered to participate in the progression of gastric cancer(GC)over the past three years.This article gives an overview of these recent research focusing on the roles of circRNAs in GC and highlights the advances.
基金supported by the National Natural Science Foundation of China(Nos.11472189 and11772224)
文摘Forward-/backward-facing steps in boundary-layer flows are often seen in engineering applications, and they have potential impacts on laminar-turbulent transition through scattering of the oncoming instability modes(e.g., Tollmien-Schlichting(T-S) waves). This issue is studied in the present paper by applying a local scattering framework, which is a rather generic mathematical framework on describing the mode scattering process. In this framework, a high-Reynolds-number triple-deck formalism is employed, and a transmission coefficient, defined as the ratio of the asymptotic amplitude of the instability mode downstream of the step to that upstream, is introduced. Through the systematical study, it has been found that both the forward-and backward-facing steps have a destabilizing effect on the oncoming T-S waves in subsonic boundary layers, this effect increases with the height of the step and/or the frequency of the T-S wave, and a backward-facing step(BFS) always has a greater impact than a forward-facing step(FFS). These facts agree with most of the previous investigations.However, one numerical study(WORNER, A., RIST, U., and WAGNER, S. Humps/steps influence on stability characteristics of two-dimensional laminar boundary layer. AIAA Journal, 41, 192–197(2003)), which was based on an ad-hoc configuration, showed an opposite impact of an FFS. Through the investigation on the specific configuration, it is revealed that the wrong conclusion was drawn by misinterpreting the numerical results.
基金funded by the National Key Research and Development Program of China(Grant No.2016YFC0503100)the National Natural Science Foundation of China(Grant Nos.31670429 and 31400346).
文摘Background:Understanding the mechanisms underlying community assembly is helpful for conservation and restoration of communities,particularly those that contain rare and endangered species like Taxus fuana,which are endemic to the Western Himalayas.The niche(limiting similarity)vs.neutral(randomness)assembly of the T.fuana forest community in Gyirong County,Tibet,China,was investigated.The net relatedness index(NRI)was calculated using a phylogenetic tree.The phylogenetic characteristics of the community and its relationships with environment were analyzed.Results:The value of the mean NRI at the community level was less than-1.96,indicating that the phylogenetic structure was overdispersed;whereas majority of the NRIs at the tree,shrub,and herb layers were within-1.96 to1.96,indicating random dispersion.Environmental factors accounted for 44.38%,46.52%,24.04%,and 14.07%of the variation at the community level,tree,shrub,and herb layer,respectively.The phylogenetic structure at the community level and tree layer were significantly influenced by both topographic and soil factors,while shrub and herb layers tended to be affected by a single environmental factor.Conclusions:Community assembly of the T.fuana forest was simultaneously affected by niche and neutral processes,and their variations were closely related to the environment.Neutral process dominated community assembly in the shrub and herb layers.However,the interaction of limiting similarity and randomness played a dominant role at the community level and tree layer;and contributed to maintenance of biodiversity stability.The synergy of multiple environmental factors had a more obvious influence on community assembly than individual environmental factors,especially at the community level.These findings would help to understand the conservation of rare and endangered tree species,such as T.fuana,in the native community;and highlight the importance of random and non-random processes in assembly and biodiversity maintenance of alpine plant communities.
基金supported by the Natural Science Foundation of Beijing (7232321)the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine (ZYYCXTD-C-202005)the State Key Program of National Natural Science of China (81930110,82230118)。
基金the National Science Foundation under Grant No.1710831,1902503,and 1912410.Any opinions,findingsconclusions or recommendations expressed in this work are those of the authors and do not necessarily reflect the views of the National Science Foundation+2 种基金This project was also partially supported by National Key Research and Development Program of China(2016YFB0402700)National Key Scientific Instrument and Equipment Development Projects of China(51727901)China Postdoctoral Science Foundation(2017M620942).
文摘Label-free nanopore sensors have emerged as a new generation technology of DNA sequencing and have been widely used for single molecule analysis.Since the firstα-hemolysin biological nanopore,various types of nanopores made of different materials have been under extensive development.Noise represents a common challenge among all types of nanopore sensors.The nanopore noise can be decomposed into four components in the frequency domain(1/f noise,white noise,dielectric noise,and amplifier noise).In this work,we reviewed and summarized the physicalmodels,origins,and reduction methods for each of these noise components.For the first time,we quantitatively benchmarked the root mean square(RMS)noise levels for different types of nanopores,demonstrating a clear material-dependent RMS noise.We anticipate this review article will enhance the understanding of nanopore sensor noises and provide an informative tutorial for developing future nanopore sensors with a high signal-to-noise ratio.
基金Project supported by the National Natural Science Foundation of China(No.11772224)。
文摘The laminar-turbulent transition in boundary-layer flows is often affected by wall imperfections, because the latter may interact with either the freestream perturbations or the oncoming boundary-layer instability modes, leading to a modification of the accumulation of the normal modes. The present paper particularly focuses on the latter mechanism in a transonic boundary layer, namely, the effect of a two-dimensional(2 D) roughness element on the oncoming Tollmien-Schlichting(T-S) modes when they propagate through the region of the rapid mean-flow distortion induced by the roughness. The wave scattering is analyzed by adapting the local scattering theory developed for subsonic boundary layers(WU, X. S. and DONG, M. A local scattering theory for the effects of isolated roughness on boundary-layer instability and transition: transmission coefficient as an eigenvalue. Journal of Fluid Mechanics, 794, 68–108(2006)) to the transonic regime, and a transmission coefficient is introduced to characterize the effect of the roughness. In the sub-transonic regime, in which the Mach number is close to, but less than, 1, the scattering system reduces to an eigenvalue problem with the transmission coefficient being the eigenvalue;while in the super-transonic regime, in which the Mach number is slightly greater than 1, the scattering system becomes a high-dimensional group of linear equations with the transmission coefficient being solved afterward. In the largeReynolds-number asymptotic theory, the K′arm′an-Guderley parameter is introduced to quantify the effect of the Mach number. A systematical parametric study is carried out,and the dependence of the transmission coefficient on the roughness shape, the frequency of the oncoming mode, and the K′arm′an-Guderley parameter is provided.