Cardiac arrest(CA)is a critical condition in the field of cardiovascular medicine.Despite successful resuscitation,patients continue to have a high mortality rate,largely due to post CA syndrome(PCAS).However,the inju...Cardiac arrest(CA)is a critical condition in the field of cardiovascular medicine.Despite successful resuscitation,patients continue to have a high mortality rate,largely due to post CA syndrome(PCAS).However,the injury and pathophysiological mechanisms underlying PCAS remain unclear.Experimental animal models are valuable tools for exploring the etiology,pathogenesis,and potential interventions for CA and PCAS.Current CA animal models include electrical induction of ventricular fibrillation(VF),myocardial infarction,high potassium,asphyxia,and hemorrhagic shock.Although these models do not fully replicate the complexity of clinical CA,the mechanistic insights they provide remain highly relevant,including post-CA brain injury(PCABI),post-CA myocardial dysfunction(PAMD),systemic ischaemia/reperfusion injury(IRI),and the persistent precipitating pathology.Summarizing the methods of establishing CA models,the challenges encountered in the modeling process,and the mechanisms of PCAS can provide a foundation for developing standardized CA modeling protocols.展开更多
本文通过高频超声检查分析了肩袖病变与肱二头肌长头肌腱(long head of the biceps brachii tendon,LHBT)病变的临床特点及相关性。文中对32例肩关节镜手术患者的术前肩关节超声检查结果与肩关节镜手术结果进行了一致性检验。按照不同...本文通过高频超声检查分析了肩袖病变与肱二头肌长头肌腱(long head of the biceps brachii tendon,LHBT)病变的临床特点及相关性。文中对32例肩关节镜手术患者的术前肩关节超声检查结果与肩关节镜手术结果进行了一致性检验。按照不同肩袖病变类型对患者进行分组,对组间LHBT病变类型的差异进行了比对分析,并对LHBT病变类型及病变总发生率与肩袖撕裂部位、范围大小均进行了相关性分析。结果证实术前肩关节超声检查结果与关节镜手术结果的诊断一致性中等偏高。LHBT病变类型在不同肩袖撕裂类型中总的差异不显著,而LHBT半脱位在不同肩袖撕裂部位的组间差异较为显著。LHBT病变类型与肩袖撕裂范围大小之间无明显相关性。随着肩袖撕裂范围的增大,LHBT病变发生率升高,二者呈正相关。由本文结果可知,LHBT病变与肩袖病变存在一定相关性,肩袖损伤的早期诊断与修复可防止LHBT病变进一步恶化。展开更多
基金supported by the National Key Research and Development Program(2021YFC3002205)the Postgraduate Research and Innovation Program of Tianjin Municipal Education Commission(2022BKY113),China.
文摘Cardiac arrest(CA)is a critical condition in the field of cardiovascular medicine.Despite successful resuscitation,patients continue to have a high mortality rate,largely due to post CA syndrome(PCAS).However,the injury and pathophysiological mechanisms underlying PCAS remain unclear.Experimental animal models are valuable tools for exploring the etiology,pathogenesis,and potential interventions for CA and PCAS.Current CA animal models include electrical induction of ventricular fibrillation(VF),myocardial infarction,high potassium,asphyxia,and hemorrhagic shock.Although these models do not fully replicate the complexity of clinical CA,the mechanistic insights they provide remain highly relevant,including post-CA brain injury(PCABI),post-CA myocardial dysfunction(PAMD),systemic ischaemia/reperfusion injury(IRI),and the persistent precipitating pathology.Summarizing the methods of establishing CA models,the challenges encountered in the modeling process,and the mechanisms of PCAS can provide a foundation for developing standardized CA modeling protocols.
文摘本文通过高频超声检查分析了肩袖病变与肱二头肌长头肌腱(long head of the biceps brachii tendon,LHBT)病变的临床特点及相关性。文中对32例肩关节镜手术患者的术前肩关节超声检查结果与肩关节镜手术结果进行了一致性检验。按照不同肩袖病变类型对患者进行分组,对组间LHBT病变类型的差异进行了比对分析,并对LHBT病变类型及病变总发生率与肩袖撕裂部位、范围大小均进行了相关性分析。结果证实术前肩关节超声检查结果与关节镜手术结果的诊断一致性中等偏高。LHBT病变类型在不同肩袖撕裂类型中总的差异不显著,而LHBT半脱位在不同肩袖撕裂部位的组间差异较为显著。LHBT病变类型与肩袖撕裂范围大小之间无明显相关性。随着肩袖撕裂范围的增大,LHBT病变发生率升高,二者呈正相关。由本文结果可知,LHBT病变与肩袖病变存在一定相关性,肩袖损伤的早期诊断与修复可防止LHBT病变进一步恶化。
