目的系统评价膳食补充剂在非小细胞肺癌(NSCLC)患者中的应用效果。方法检索PubMed、Embase、Cochrane Library和Web of Science数据库中关于NSCLC患者使用膳食补充剂的研究,检索时间从建库至2024年4月。将NSCLC患者分为试验组(使用膳食...目的系统评价膳食补充剂在非小细胞肺癌(NSCLC)患者中的应用效果。方法检索PubMed、Embase、Cochrane Library和Web of Science数据库中关于NSCLC患者使用膳食补充剂的研究,检索时间从建库至2024年4月。将NSCLC患者分为试验组(使用膳食补充剂)和对照组(未使用膳食补充剂),采用RevMan 5.2和Stata 15.0软件对两组患者的生存情况、不良反应发生情况、炎症反应指标、生理指标及营养摄入量进行Meta分析。结果试验组患者的无进展生存期(PFS)明显长于对照组,差异有统计学意义[加权均数差(WMD)=1.20,95%置信区间(CI):0.97~1.44,P﹤0.01];试验组患者的总生存率高于对照组,差异有统计学意义[风险比(HR)=1.27,95%CI:1.05~1.54,P=0.012)]。试验组患者2~3级食管炎发生率明显低于对照组,差异有统计学意义[比值比(OR)=0.17,95%CI:0.10~0.32,P﹤0.01]。试验组患者C反应蛋白(CRP)和白细胞介素-6(IL-6)水平均明显低于对照组,差异均有统计学意义[标准化均差(SMD)=-1.02,95%CI:-1.77~-0.27,P﹤0.01;WMD=-6.40,95%CI:-9.08~-3.72,P﹤0.01]。试验组患者体重减轻发生率明显低于对照组,差异有统计学意义(OR=0.11,95%CI:0.06~0.20,P﹤0.01);试验组患者体重变化优于对照组,差异有统计学意义(WMD=3.67,95%CI:0.38~6.96,P=0.029)。试验组患者能量和蛋白质摄入量均高于对照组,差异均有统计学意义(WMD=402.80,95%CI:249.01~556.59,P﹤0.01;WMD=18.00,95%CI:4.15~31.85,P=0.011)。结论使用膳食补充剂可改善NSCLC患者的生存情况,减少不良反应,降低炎症反应指标及体重减轻发生率,并增加能量和蛋白质的摄入量,有可能成为改善NSCLC患者预后的有效方法。展开更多
The effects of low-Co AB_5 type hydrogen storage alloys prepared by quenchingand annealing on the performances of MH-Ni batteries were investigated, and the characteristics ofthe low-Co AB_5 type hydrogen storage allo...The effects of low-Co AB_5 type hydrogen storage alloys prepared by quenchingand annealing on the performances of MH-Ni batteries were investigated, and the characteristics ofthe low-Co AB_5 type hydrogen storage alloys were compared with those of the high-Co AB_5 typehydrogen storage alloy as well. The results showed that the faster the cooling of the low-Cohydrogen storage alloy is, the better homogeneity of the chemical composition for the alloy and thelonger cycle life of the battery are, but the electrochemical discharge capacity and high-ratedischarge ability are reduced. The high-rate discharge ability and charge retention of MH-Nibatteries for the conventional as-cast annealed low-Co hydrogen storage alloy were superior to thosefor the rapidly quenched low-Co hydrogen storage alloy and the high-Co hydrogen storage alloy, buta little inferior in the cycle life.展开更多
The availability of elite germplasm resources with high yield and quality potentials is very important for development of cultivars in wheat. Thus, seeking such resources has been the continuous effort of breeder comm...The availability of elite germplasm resources with high yield and quality potentials is very important for development of cultivars in wheat. Thus, seeking such resources has been the continuous effort of breeder community. In this study, genetic analysis of a novel resource, Triticum spelta line CSCR6, from Australia was made by use of a recombination inbred line （RIL） population of 82 individuals from the cross between CSCR6 and another Australian hexaploid wheat cultivar, Lang. Data of a multiple environmental test was employed to genetically dissect quantitative trait loci （QTL） for agronomic traits such as plant height （PH）, spike length （SL）, spikelet per spike （SPI）, grain number per spike （GNS） and thousand grains weight （TGW） and for quality traits including grain protein content （GPC）, gluten content （GC）, grain hardness （GH）, falling number （FN） and sedimentation value （SV）. A 24 QTLs with additive effects were detected for all the investigated traits, and were located on chromosomes 1B, 1D, 2B, 3A, 3B, 3D, 4B, 5A, 5B, 7A, and 7B, respectively. Some QTLs located on 2B and 4B showed higher explanation of phenotypic variances and were not obviously interacted with environment. A QTL in the marker interval of wPT-5334-wPT-4918 （near the locus barc 0199） on 4B gave the highest contribution ratio of 30.76% on PH, while Qgpc-4B and Qgc-4B gave 13.07 and 14.70% contribution ratio on GPC and GC, respectively. Qph-2B, Qgns-2B, and Qgpc-2B showed 13.36, 10.00, and 10.79% contribution ratio on PH, GNS and GPC, respectively. Also, a QTL on 5A, Qsl- 5A, could explain 25.12% of phenotypic variance on SL. For most of agronomic and quality traits, CSCR6 alleles produced increase effects. The fact that a number of loci affecting the investigated traits were detected in T. spelta line CSCR6 revealed that it could offer a new opportunity for the manipulation of these traits in wheat breeding programs.展开更多
Using 18 indica rice varieties with different panicle weight, the photosynthetic characteristics and assimilate's accumulation and transformation in heavy panicle type of rice(HPT)were studied. The results showed ...Using 18 indica rice varieties with different panicle weight, the photosynthetic characteristics and assimilate's accumulation and transformation in heavy panicle type of rice(HPT)were studied. The results showed that the net photosynthetic rate of the flag leaf in HPT after heading was obviously higher than that in medium panicle type(MPT)and light panicle type(LPT). The reason for the high net photosynthetic rate in HPT was the increase of Rubisco activities and chlorophyll content, and keeping high assimilate ability to CO2 under high and low light intensity, high temperature and low CO2 content, and light midday depression and wide adaptability to environmental conditions. The high net photosynthetic rate of HPT might be also the results of its excellent stomatal characteristics and higher total quantity of stomatal opening degrees(stomatal density X stomatal opening degrees). There was a large amount of dry matter production after heading and obvious high assimilate's transformation to panicle in HPT.展开更多
The phytophagous insect, Epiblema strenuana, is an effective biocontrol agent against Ambrosia and Parthenium, and was introduced to China in 1990 to control Ambrosia artemisiifolia. After a small scale release in Hun...The phytophagous insect, Epiblema strenuana, is an effective biocontrol agent against Ambrosia and Parthenium, and was introduced to China in 1990 to control Ambrosia artemisiifolia. After a small scale release in Hunan Province, E. strenuana established and begun to spread. Host specificity and feeding studies in Hunan have indicated that there are four host plants in China, A. artemisiifolia, A. trifida, Xanthium sibiricum and Parthenium hysterophorus. These plants are all weeds that need to be controlled. However, there are still some different views among scientists about the merits of this release because of potential effects on non-target species such as Helianthus annuus, and uncertainty about climatic suitability. To address these concerns, the CLIMEX system was used to predict the possibility of establishment of E. strenuana with A. artemisiifolia, A. trifida, and P. hysterophorus at 85 meteorological locations. Also, the probability of E. strenuana co-establishing with A. artemisiifolia, A. trifida or P. hysterophorus was evaluated quantitatively by bioclimatic risk index (BCRI) transferred from ecoclimate index (EI). Moreover, the hypothetical adaptation of E. strenuana to H. annuus as a host, were evaluated by bioclimate matching. These results help to predict the potential spread of A. artemisiifolia, A. trifida, P. hysterophorus and evaluate the merits of further releases of E. strenuana in China.展开更多
文摘The effects of low-Co AB_5 type hydrogen storage alloys prepared by quenchingand annealing on the performances of MH-Ni batteries were investigated, and the characteristics ofthe low-Co AB_5 type hydrogen storage alloys were compared with those of the high-Co AB_5 typehydrogen storage alloy as well. The results showed that the faster the cooling of the low-Cohydrogen storage alloy is, the better homogeneity of the chemical composition for the alloy and thelonger cycle life of the battery are, but the electrochemical discharge capacity and high-ratedischarge ability are reduced. The high-rate discharge ability and charge retention of MH-Nibatteries for the conventional as-cast annealed low-Co hydrogen storage alloy were superior to thosefor the rapidly quenched low-Co hydrogen storage alloy and the high-Co hydrogen storage alloy, buta little inferior in the cycle life.
基金the Visiting Scientist Scholarship and Wheat Breeding Research Project of Hebei Province, China (06220114D)
文摘The availability of elite germplasm resources with high yield and quality potentials is very important for development of cultivars in wheat. Thus, seeking such resources has been the continuous effort of breeder community. In this study, genetic analysis of a novel resource, Triticum spelta line CSCR6, from Australia was made by use of a recombination inbred line （RIL） population of 82 individuals from the cross between CSCR6 and another Australian hexaploid wheat cultivar, Lang. Data of a multiple environmental test was employed to genetically dissect quantitative trait loci （QTL） for agronomic traits such as plant height （PH）, spike length （SL）, spikelet per spike （SPI）, grain number per spike （GNS） and thousand grains weight （TGW） and for quality traits including grain protein content （GPC）, gluten content （GC）, grain hardness （GH）, falling number （FN） and sedimentation value （SV）. A 24 QTLs with additive effects were detected for all the investigated traits, and were located on chromosomes 1B, 1D, 2B, 3A, 3B, 3D, 4B, 5A, 5B, 7A, and 7B, respectively. Some QTLs located on 2B and 4B showed higher explanation of phenotypic variances and were not obviously interacted with environment. A QTL in the marker interval of wPT-5334-wPT-4918 （near the locus barc 0199） on 4B gave the highest contribution ratio of 30.76% on PH, while Qgpc-4B and Qgc-4B gave 13.07 and 14.70% contribution ratio on GPC and GC, respectively. Qph-2B, Qgns-2B, and Qgpc-2B showed 13.36, 10.00, and 10.79% contribution ratio on PH, GNS and GPC, respectively. Also, a QTL on 5A, Qsl- 5A, could explain 25.12% of phenotypic variance on SL. For most of agronomic and quality traits, CSCR6 alleles produced increase effects. The fact that a number of loci affecting the investigated traits were detected in T. spelta line CSCR6 revealed that it could offer a new opportunity for the manipulation of these traits in wheat breeding programs.
文摘Using 18 indica rice varieties with different panicle weight, the photosynthetic characteristics and assimilate's accumulation and transformation in heavy panicle type of rice(HPT)were studied. The results showed that the net photosynthetic rate of the flag leaf in HPT after heading was obviously higher than that in medium panicle type(MPT)and light panicle type(LPT). The reason for the high net photosynthetic rate in HPT was the increase of Rubisco activities and chlorophyll content, and keeping high assimilate ability to CO2 under high and low light intensity, high temperature and low CO2 content, and light midday depression and wide adaptability to environmental conditions. The high net photosynthetic rate of HPT might be also the results of its excellent stomatal characteristics and higher total quantity of stomatal opening degrees(stomatal density X stomatal opening degrees). There was a large amount of dry matter production after heading and obvious high assimilate's transformation to panicle in HPT.
基金supported by National Natural Science Foundation of China(39770510)National 10th“Five-year Plan”Key Research Program(2001BA611B-06-1-5).
文摘The phytophagous insect, Epiblema strenuana, is an effective biocontrol agent against Ambrosia and Parthenium, and was introduced to China in 1990 to control Ambrosia artemisiifolia. After a small scale release in Hunan Province, E. strenuana established and begun to spread. Host specificity and feeding studies in Hunan have indicated that there are four host plants in China, A. artemisiifolia, A. trifida, Xanthium sibiricum and Parthenium hysterophorus. These plants are all weeds that need to be controlled. However, there are still some different views among scientists about the merits of this release because of potential effects on non-target species such as Helianthus annuus, and uncertainty about climatic suitability. To address these concerns, the CLIMEX system was used to predict the possibility of establishment of E. strenuana with A. artemisiifolia, A. trifida, and P. hysterophorus at 85 meteorological locations. Also, the probability of E. strenuana co-establishing with A. artemisiifolia, A. trifida or P. hysterophorus was evaluated quantitatively by bioclimatic risk index (BCRI) transferred from ecoclimate index (EI). Moreover, the hypothetical adaptation of E. strenuana to H. annuus as a host, were evaluated by bioclimate matching. These results help to predict the potential spread of A. artemisiifolia, A. trifida, P. hysterophorus and evaluate the merits of further releases of E. strenuana in China.
