Laser-plasma accelerated(LPA)proton bunches are now applied for research fields ranging from ultra-high-dose-rate radiobiology to material science.Yet,the capabilities to characterize the spectrally and angularly broa...Laser-plasma accelerated(LPA)proton bunches are now applied for research fields ranging from ultra-high-dose-rate radiobiology to material science.Yet,the capabilities to characterize the spectrally and angularly broad LPA bunches lag behind the rapidly evolving applications.The OCTOPOD translates the angularly resolved spectral characterization of LPA proton bunches into the spatially resolved detection of the volumetric dose distribution deposited in a liquid scintillator.Up to 24 multi-pinhole arrays record projections of the scintillation light distribution and allow for tomographic reconstruction of the volumetric dose deposition pattern,from which proton spectra may be retrieved.Applying the OCTOPOD at a cyclotron,we show the reliable retrieval of various spatial dose deposition patterns and detector sensitivity over a broad dose range.Moreover,the OCTOPOD was installed at an LPA proton source,providing real-time data on proton acceleration performance and attesting the system optimal performance in the harsh laser-plasma environment.展开更多
Laser plasma accelerators(LPAs)enable the generation of intense and short proton bunches on a micrometre scale,thus offering new experimental capabilities to research fields such as ultra-high dose rate radiobiology o...Laser plasma accelerators(LPAs)enable the generation of intense and short proton bunches on a micrometre scale,thus offering new experimental capabilities to research fields such as ultra-high dose rate radiobiology or material analysis.Being spectrally broadband,laser-accelerated proton bunches allow for tailored volumetric dose deposition in a sample via single bunches to excite or probe specific sample properties.The rising number of such experiments indicates a need for diagnostics providing spatially resolved characterization of dose distributions with volumes of approximately 1 cm^(3) for single proton bunches to allow for fast online feedback.Here we present the scintillator-based miniSCIDOM detector for online single-bunch tomographic reconstruction of dose distributions in volumes of up to approximately 1 cm^(3).The detector achieves a spatial resolution below 500μm and a sensitivity of 100 mGy.The detector performance is tested at a proton therapy cyclotron and an LPA proton source.The experiments’primary focus is the characterization of the scintillator’s ionization quenching behaviour.展开更多
基金the DRACO laser team and UPTD team for excellent experiment supportpartially supported by H2020 Laserlab Europe V(PRISES,contract No.871124)+2 种基金by the European Union’s Horizon 2020 Research and Innovation Programme Impulse(grant agreement No.871161)the support of the Weizmann-Helmholtz Laboratory for Laser Matter Interaction(WHELMI)The experimental part of the University Proton Therapy Dresden(UPTD)facility has received funding from the European Union’s Horizon 2020 Research and Innovation Program(grant agreement No.730983(INSPIRE))
文摘Laser-plasma accelerated(LPA)proton bunches are now applied for research fields ranging from ultra-high-dose-rate radiobiology to material science.Yet,the capabilities to characterize the spectrally and angularly broad LPA bunches lag behind the rapidly evolving applications.The OCTOPOD translates the angularly resolved spectral characterization of LPA proton bunches into the spatially resolved detection of the volumetric dose distribution deposited in a liquid scintillator.Up to 24 multi-pinhole arrays record projections of the scintillation light distribution and allow for tomographic reconstruction of the volumetric dose deposition pattern,from which proton spectra may be retrieved.Applying the OCTOPOD at a cyclotron,we show the reliable retrieval of various spatial dose deposition patterns and detector sensitivity over a broad dose range.Moreover,the OCTOPOD was installed at an LPA proton source,providing real-time data on proton acceleration performance and attesting the system optimal performance in the harsh laser-plasma environment.
基金partially supported by H2020 Laserlab Europe V (PRISES, Contract No. 871124)the European Union’s Horizon 2020 Research and Innovation Programme Impulse (Grant agreement No. 871161)the support of the Weizmann-Helmholtz Laboratory for Laser Matter Interaction (WHELMI)
文摘Laser plasma accelerators(LPAs)enable the generation of intense and short proton bunches on a micrometre scale,thus offering new experimental capabilities to research fields such as ultra-high dose rate radiobiology or material analysis.Being spectrally broadband,laser-accelerated proton bunches allow for tailored volumetric dose deposition in a sample via single bunches to excite or probe specific sample properties.The rising number of such experiments indicates a need for diagnostics providing spatially resolved characterization of dose distributions with volumes of approximately 1 cm^(3) for single proton bunches to allow for fast online feedback.Here we present the scintillator-based miniSCIDOM detector for online single-bunch tomographic reconstruction of dose distributions in volumes of up to approximately 1 cm^(3).The detector achieves a spatial resolution below 500μm and a sensitivity of 100 mGy.The detector performance is tested at a proton therapy cyclotron and an LPA proton source.The experiments’primary focus is the characterization of the scintillator’s ionization quenching behaviour.
