Some new 2-aryl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-ones have been prepared through cyclocondensation of 2-amino 1H-pyrrole-3-carboxamides with aromatic aldehydes followed by air oxidation in the presence of 3-me...Some new 2-aryl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-ones have been prepared through cyclocondensation of 2-amino 1H-pyrrole-3-carboxamides with aromatic aldehydes followed by air oxidation in the presence of 3-methyl-1-（4-sulfonic acid）butylimidazolium hydrogen sulfate[（CH;）;SO;HMIM][HSO;],a Br（?）nsted-acidic ionic liquid,as a green and reusable catalyst in solvent-free conditions.展开更多
A highly efficient synthesis of 2-aryl-quinazolin-4（3H）ones was performed by one-pot oxidative heterocyclization of 2- aminobenzamide with aldehydes in the presence of potassium permanganate in dimethylacetamide und...A highly efficient synthesis of 2-aryl-quinazolin-4（3H）ones was performed by one-pot oxidative heterocyclization of 2- aminobenzamide with aldehydes in the presence of potassium permanganate in dimethylacetamide under microwave irradiation.展开更多
A rapid and efficient method for the synthesis of isoxazolo[5,4-d]pyrimidin-4（5H）-ones has been developed through cyclocondensation of 5-aminoisoxazole-4-carboxamides with orthoesters under conventional heating and ...A rapid and efficient method for the synthesis of isoxazolo[5,4-d]pyrimidin-4（5H）-ones has been developed through cyclocondensation of 5-aminoisoxazole-4-carboxamides with orthoesters under conventional heating and solvent-free microwave irradiation with solid acid catalysis. In comparison, the reactions are faster and the yields are higher under microwave irradiation.展开更多
A new one-pot neat synthesis of some 5-aryl-2,4-dihydro-3H- 1,2,4-triazol-3-ones through cyclocondensation of ethyl carbazate with aryl nitriles catalyzed by DMAP as an efficient and basic nucleophilic catalyst is des...A new one-pot neat synthesis of some 5-aryl-2,4-dihydro-3H- 1,2,4-triazol-3-ones through cyclocondensation of ethyl carbazate with aryl nitriles catalyzed by DMAP as an efficient and basic nucleophilic catalyst is described.展开更多
A facile one-pot synthesis of new 3-arylthieno[2,3-d]pyrimidine-2,4（1H,3H）-diones via base-catalyzed cyclocondensation of ethyl 2-amino-4,5-dimethylthiophene-3-carboxylate with aryl isocyanates is described.
Microwave-assisted synthesis of new 2-arylpyrimido[4′,5′：4,5]thiazolo[3,2-α]benzimidazol-4（3H）-ones from 3-aminothia- zolo[3,2-α]benzimidazol-2-earboxamide and aroyl halides in solvent-free condition is describ...Microwave-assisted synthesis of new 2-arylpyrimido[4′,5′：4,5]thiazolo[3,2-α]benzimidazol-4（3H）-ones from 3-aminothia- zolo[3,2-α]benzimidazol-2-earboxamide and aroyl halides in solvent-free condition is described. In comparison with classical conditions the reactions are faster and the yields are higher under microwave irradiation.展开更多
Isatoic anhydride was reacted with several L-amino acids to give the corresponding （2S）-N-（o-aminobenzoyl）-2-alkylaminoacetic acids. The latter compounds were treated with phosphoryl chloride under reflux temperat...Isatoic anhydride was reacted with several L-amino acids to give the corresponding （2S）-N-（o-aminobenzoyl）-2-alkylaminoacetic acids. The latter compounds were treated with phosphoryl chloride under reflux temperature to afford the cyclized products, （3S）-3-alkyl-3,4-dihydro- 1 H- 1,4-benzodiazepin-2,5-diones. 2007 M. Bakavoli. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.展开更多
Heteropoly acid H3PW12040 （PW） has been used as an effective catalyst for the synthesis of thieno[2,3-d]pyrimidin-4（3H）-one derivatives. The present methodology offers several advantages, such as high yields, shor...Heteropoly acid H3PW12040 （PW） has been used as an effective catalyst for the synthesis of thieno[2,3-d]pyrimidin-4（3H）-one derivatives. The present methodology offers several advantages, such as high yields, short reaction times, mild reaction condition and a recyclable catalyst with a very easy work up.展开更多
文摘Some new 2-aryl-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-ones have been prepared through cyclocondensation of 2-amino 1H-pyrrole-3-carboxamides with aromatic aldehydes followed by air oxidation in the presence of 3-methyl-1-（4-sulfonic acid）butylimidazolium hydrogen sulfate[（CH;）;SO;HMIM][HSO;],a Br（?）nsted-acidic ionic liquid,as a green and reusable catalyst in solvent-free conditions.
文摘A highly efficient synthesis of 2-aryl-quinazolin-4（3H）ones was performed by one-pot oxidative heterocyclization of 2- aminobenzamide with aldehydes in the presence of potassium permanganate in dimethylacetamide under microwave irradiation.
文摘A rapid and efficient method for the synthesis of isoxazolo[5,4-d]pyrimidin-4（5H）-ones has been developed through cyclocondensation of 5-aminoisoxazole-4-carboxamides with orthoesters under conventional heating and solvent-free microwave irradiation with solid acid catalysis. In comparison, the reactions are faster and the yields are higher under microwave irradiation.
文摘A new one-pot neat synthesis of some 5-aryl-2,4-dihydro-3H- 1,2,4-triazol-3-ones through cyclocondensation of ethyl carbazate with aryl nitriles catalyzed by DMAP as an efficient and basic nucleophilic catalyst is described.
文摘A facile one-pot synthesis of new 3-arylthieno[2,3-d]pyrimidine-2,4（1H,3H）-diones via base-catalyzed cyclocondensation of ethyl 2-amino-4,5-dimethylthiophene-3-carboxylate with aryl isocyanates is described.
文摘Microwave-assisted synthesis of new 2-arylpyrimido[4′,5′：4,5]thiazolo[3,2-α]benzimidazol-4（3H）-ones from 3-aminothia- zolo[3,2-α]benzimidazol-2-earboxamide and aroyl halides in solvent-free condition is described. In comparison with classical conditions the reactions are faster and the yields are higher under microwave irradiation.
文摘Isatoic anhydride was reacted with several L-amino acids to give the corresponding （2S）-N-（o-aminobenzoyl）-2-alkylaminoacetic acids. The latter compounds were treated with phosphoryl chloride under reflux temperature to afford the cyclized products, （3S）-3-alkyl-3,4-dihydro- 1 H- 1,4-benzodiazepin-2,5-diones. 2007 M. Bakavoli. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
文摘Heteropoly acid H3PW12040 （PW） has been used as an effective catalyst for the synthesis of thieno[2,3-d]pyrimidin-4（3H）-one derivatives. The present methodology offers several advantages, such as high yields, short reaction times, mild reaction condition and a recyclable catalyst with a very easy work up.
