Malaria is much more common in pregnant women, especially during the third trimester of pregnancy, causing congenital infestation. Acute and severe complications are noted, including malignant malaria access and mater...Malaria is much more common in pregnant women, especially during the third trimester of pregnancy, causing congenital infestation. Acute and severe complications are noted, including malignant malaria access and maternal and fetal mortality. Method: This was a three-month descriptive and analytical multicenter study, running from 1st January to 31st March 2015, conducted in 16 maternity hospitals at different levels of the health system pyramid. Results: Out of a total of 1772 mothers recruited for this study, 276 cases were tested positive (umbilical cordon and newborn’s heel). Among them, we reported 130 cases tested positive at newborn’s heel with congenital infestation confirmed by sampling on day 0, with a frequency of 7.3%. The average age of the mothers was 26 ± 14 years. With a predominance in the 20 - 35 age group (4.7%). Among mothers who were not exposed to preventive intermittent sulfadoxine pyrimethamine (IPT/SP) in malaria prevention, 6.1% of newborns tested positive. Of these, mothers who had less than 4 prenatal visits during pregnancy had a congenital malaria rate of 7.3%. Conclusion: Congenital malaria infestation exists in newborns despite adequate measures used in pregnant women (SP, antimalarial drugs). In Guinea, It is often found in newborns of mothers who suffer from malaria during pregnancy and whose prenatal cares are not regular.展开更多
Objective: This study was conducted to evaluate the role of colposcopy in the screening of cervical cancer at the UTH in Conakry. Material and Methods: We conducted a descriptive study on over a period of 18 months of...Objective: This study was conducted to evaluate the role of colposcopy in the screening of cervical cancer at the UTH in Conakry. Material and Methods: We conducted a descriptive study on over a period of 18 months of from the 1 July 2004 to December 31, 2005 in the CHU of Conakry Any women aged from 25 to 65 years old who has agreed to the screening of cervical cancer by colposcopy was included. Statistical tests of sensitivity, specificity, and predictive values positive and negative were computed directly and compare among all participants. Results: During the study period, we included a total of 9339 women. For all precancerous and cancerous lesions, sensitivity and specificity were 93% and 64% respectively. With a positive predictive value of 46% and the negative predictive value of 90%, low and high grade precancerous lesions were found with: a sensitivity of 91%, the specificity of 64%. The positive predictive value of 37%, and the negative predictive value of 91% were estimed. Intra epithelial lesions (LIEBG) low-grade squamous sensitivity was 94%, specificity of 62%, the positive predictive value of 31%, the negative predictive value of 95%. For lesions intra epithelial highgrade squamous (LIEHG), the sensitivity was 85%, 10%, the positive predictive value of 74% specificity, negative predictive value of 95%. Conclusion: Colposcopy is a reference method of detection of precancerous lesions of the cervix to promote cancer.展开更多
文摘Malaria is much more common in pregnant women, especially during the third trimester of pregnancy, causing congenital infestation. Acute and severe complications are noted, including malignant malaria access and maternal and fetal mortality. Method: This was a three-month descriptive and analytical multicenter study, running from 1st January to 31st March 2015, conducted in 16 maternity hospitals at different levels of the health system pyramid. Results: Out of a total of 1772 mothers recruited for this study, 276 cases were tested positive (umbilical cordon and newborn’s heel). Among them, we reported 130 cases tested positive at newborn’s heel with congenital infestation confirmed by sampling on day 0, with a frequency of 7.3%. The average age of the mothers was 26 ± 14 years. With a predominance in the 20 - 35 age group (4.7%). Among mothers who were not exposed to preventive intermittent sulfadoxine pyrimethamine (IPT/SP) in malaria prevention, 6.1% of newborns tested positive. Of these, mothers who had less than 4 prenatal visits during pregnancy had a congenital malaria rate of 7.3%. Conclusion: Congenital malaria infestation exists in newborns despite adequate measures used in pregnant women (SP, antimalarial drugs). In Guinea, It is often found in newborns of mothers who suffer from malaria during pregnancy and whose prenatal cares are not regular.
文摘Objective: This study was conducted to evaluate the role of colposcopy in the screening of cervical cancer at the UTH in Conakry. Material and Methods: We conducted a descriptive study on over a period of 18 months of from the 1 July 2004 to December 31, 2005 in the CHU of Conakry Any women aged from 25 to 65 years old who has agreed to the screening of cervical cancer by colposcopy was included. Statistical tests of sensitivity, specificity, and predictive values positive and negative were computed directly and compare among all participants. Results: During the study period, we included a total of 9339 women. For all precancerous and cancerous lesions, sensitivity and specificity were 93% and 64% respectively. With a positive predictive value of 46% and the negative predictive value of 90%, low and high grade precancerous lesions were found with: a sensitivity of 91%, the specificity of 64%. The positive predictive value of 37%, and the negative predictive value of 91% were estimed. Intra epithelial lesions (LIEBG) low-grade squamous sensitivity was 94%, specificity of 62%, the positive predictive value of 31%, the negative predictive value of 95%. For lesions intra epithelial highgrade squamous (LIEHG), the sensitivity was 85%, 10%, the positive predictive value of 74% specificity, negative predictive value of 95%. Conclusion: Colposcopy is a reference method of detection of precancerous lesions of the cervix to promote cancer.
